tetrahydrodiferuloylmethane, 36062-04-1

Articles:

PubMed:	Differential cellular uptake and metabolism of curcuminoids in monocytes/macrophages: regulatory effects on lipid accumulation.
PubMed:	Tetrahydrocurcumin induces G2/M cell cycle arrest and apoptosis involving p38 MAPK activation in human breast cancer cells.
PubMed:	A high-throughput quantification method of curcuminoids and curcumin metabolites in human plasma via high-performance liquid chromatography/tandem mass spectrometry.
PubMed:	Comparative absorption of curcumin formulations.
PubMed:	Curcuma longa extract associated with white pepper lessens high fat diet-induced inflammation in subcutaneous adipose tissue.
PubMed:	Chemopreventative effects of tetrahydrocurcumin on human diseases.
PubMed:	Development of a liquid chromatographic method for the simultaneous quantification of curcumin, β-arteether, tetrahydrocurcumin and dihydroartemisinin. Application to lipid-based formulations.
PubMed:	Structure-activity relationship analysis of curcumin analogues on anti-influenza virus activity.
PubMed:	Turmeric curcumin inhibits entry of all hepatitis C virus genotypes into human liver cells.
PubMed:	Microbial transformation of curcumin to its derivatives with a novel Pichia kudriavzevii ZJPH0802 strain.
PubMed:	Novel racemic tetrahydrocurcuminoid dihydropyrimidinone analogues as potent acetylcholinesterase inhibitors.
PubMed:	Synthesis of amino acid conjugates of tetrahydrocurcumin and evaluation of their antibacterial and anti-mutagenic properties.
PubMed:	Curcumin and aging.
PubMed:	Development, characterization and permeability assessment based on caco-2 monolayers of self-microemulsifying floating tablets of tetrahydrocurcumin.
PubMed:	Highly stabilized curcumin nanoparticles tested in an in vitro blood-brain barrier model and in Alzheimer's disease Tg2576 mice.
PubMed:	Synthesis of quinoline derivatives of tetrahydrocurcumin and zingerone and evaluation of their antioxidant and antibacterial attributes.
PubMed:	Infusion pharmacokinetics of Lipocurc™ (liposomal curcumin) and its metabolite tetrahydrocurcumin in Beagle dogs.
PubMed:	Tissue distribution of (Lipocurc™) liposomal curcumin and tetrahydrocurcumin following two- and eight-hour infusions in Beagle dogs.
PubMed:	Inhibition of Ca(2+) release-activated Ca(2+) channel (CRAC) by curcumin and caffeic acid phenethyl ester (CAPE) via electrophilic addition to a cysteine residue of Orai1.
PubMed:	Antioxidant combinations protect oral fibroblasts against metal-induced toxicity.
PubMed:	Formation of tetrahydrocurcumin by reduction of curcumin with cultured plant cells of Marchantia polymorpha.
PubMed:	Tetrahydrocurcumin ameliorates homocysteinylated cytochrome-c mediated autophagy in hyperhomocysteinemia mice after cerebral ischemia.
PubMed:	Tetrahydrocurcumin extends life span and inhibits the oxidative stress response by regulating the FOXO forkhead transcription factor.
PubMed:	Tetrahydrocurcumin alleviates hypertension, aortic stiffening and oxidative stress in rats with nitric oxide deficiency.
PubMed:	Regulatory effects of curcumin on lipid accumulation in monocytes/macrophages.
PubMed:	Enhancement of curcumin oral absorption and pharmacokinetics of curcuminoids and curcumin metabolites in mice.
PubMed:	Molecular docking studies of curcumin analogs with phospholipase A2.
PubMed:	Tetrahydrocurcumin, a major metabolite of curcumin, induced autophagic cell death through coordinative modulation of PI3K/Akt-mTOR and MAPK signaling pathways in human leukemia HL-60 cells.
PubMed:	Tetrahydrocurcumin is more effective than curcumin in preventing azoxymethane-induced colon carcinogenesis.
PubMed:	Optimized turmeric extract reduces β-Amyloid and phosphorylated Tau protein burden in Alzheimer's transgenic mice.
PubMed:	Microbial conversion of curcumin into colorless hydroderivatives by the endophytic fungus Diaporthe sp. associated with Curcuma longa.
PubMed:	Discovery of the curcumin metabolic pathway involving a unique enzyme in an intestinal microorganism.
PubMed:	Bioactive antioxidant mixtures promote proliferation and migration on human oral fibroblasts.
PubMed:	Antioxidant and vascular protective effects of curcumin and tetrahydrocurcumin in rats with L-NAME-induced hypertension.
PubMed:	In vitro inhibitory effect of tetrahydrocurcuminoids on Fusarium proliferatum growth and fumonisin B₁ biosynthesis.
PubMed:	Controlled release of oral tetrahydrocurcumin from a novel self-emulsifying floating drug delivery system (SEFDDS).
PubMed:	Revisiting dietary antioxidants, neurodegeneration and dementia.
PubMed:	Tetrahydrocurcumin confers protection against amyloid β-induced toxicity.
PubMed:	Tetrahydrocurcuminoid cream plus targeted narrowband UVB phototherapy for vitiligo: a preliminary randomized controlled study.
PubMed:	A liquid chromatography-tandem mass spectrometric method for quantification of curcuminoids in cell medium and mouse plasma.
PubMed:	Antihyperlipidemic effect of chlorogenic acid and tetrahydrocurcumin in rats subjected to diabetogenic agents.
PubMed:	Antioxidants counteract nicotine and promote migration via RacGTP in oral fibroblast cells.
PubMed:	Curcuminoids activate p38 MAP kinases and promote UVB-dependent signalling in keratinocytes.
PubMed:	Monoacetylcurcumin strongly regulates inflammatory responses through inhibition of NF-kappaB activation.
PubMed:	Combined treatment of tetrahydrocurcumin and chlorogenic acid exerts potential antihyperglycemic effect on streptozotocin-nicotinamide-induced diabetic rats.
PubMed:	Comparative and combined effect of chlorogenic acid and tetrahydrocurcumin on antioxidant disparities in chemical induced experimental diabetes.
PubMed:	Assessing the neuroprotective effect of antioxidant food factors by application of lipid-derived dopamine modification adducts.
PubMed:	Optimized turmeric extracts have potent anti-amyloidogenic effects.
PubMed:	Cardioprotective effect of tetrahydrocurcumin and rutin on lipid peroxides and antioxidants in experimentally induced myocardial infarction in rats.
PubMed:	Dimethoxycurcumin, a Synthetic Curcumin Analogue, Induces Heme Oxygenase-1 Expression through Nrf2 Activation in RAW264.7 Macrophages.
PubMed:	Curcumin is a potent DNA hypomethylation agent.
PubMed:	Modulation of macrophage functions by compounds isolated from Zingiber officinale.
PubMed:	Natural derivatives of curcumin attenuate the Wnt/beta-catenin pathway through down-regulation of the transcriptional coactivator p300.
PubMed:	Tetrahydrocurcumin inhibits HT1080 cell migration and invasion via downregulation of MMPs and uPA.
PubMed:	Comparative anti-inflammatory activities of curcumin and tetrahydrocurcumin based on the phenolic O-H bond dissociation enthalpy, ionization potential and quantum chemical descriptor.
PubMed:	Dimethoxycurcumin, a synthetic curcumin analogue with higher metabolic stability, inhibits NO production, inducible NO synthase expression and NF-kappaB activation in RAW264.7 macrophages activated with LPS.
PubMed:	Curcumin structure-function, bioavailability, and efficacy in models of neuroinflammation and Alzheimer's disease.
PubMed:	Inhibition of monoamine oxidase-B by the polyphenolic compound, curcumin and its metabolite tetrahydrocurcumin, in a model of Parkinson's disease induced by MPTP neurodegeneration in mice.
PubMed:	Anti-cancer and anti-angiogenic effects of curcumin and tetrahydrocurcumin on implanted hepatocellular carcinoma in nude mice.
PubMed:	Effect of tetrahydrocurcumin on insulin receptor status in type 2 diabetic rats: studies on insulin binding to erythrocytes.
PubMed:	Comparative radical-scavenging activity of curcumin and tetrahydrocurcumin with thiols as measured by the induction period method.
PubMed:	Influence of tetrahydrocurcumin on tail tendon collagen contents and its properties in rats with streptozotocin-nicotinamide-induced type 2 diabetes.
PubMed:	Curcumin attenuates dimethylnitrosamine-induced liver injury in rats through Nrf2-mediated induction of heme oxygenase-1.
PubMed:	Antihyperlipidemic effect of curcumin and tetrahydrocurcumin in experimental type 2 diabetic rats.
PubMed:	Influence of tetrahydrocurcumin on hepatic and renal functional markers and protein levels in experimental type 2 diabetic rats.
PubMed:	Influence of tetrahydrocurcumin on erythrocyte membrane bound enzymes and antioxidant status in experimental type 2 diabetic rats.
PubMed:	Tetrahydrocurcumin prevents brain lipid peroxidation in streptozotocin-induced diabetic rats.
PubMed:	The study of human skin irritation of a novel herbal skin care product and ingredients by human single closed patch testing.
PubMed:	Roles of heme oxygenase-1 in curcumin-induced growth inhibition in rat smooth muscle cells.
PubMed:	Nephroprotective and hepatoprotective effects of curcuminoids.
PubMed:	Curcumin, demethoxycurcumin, bisdemethoxycurcumin, tetrahydrocurcumin and turmerones differentially regulate anti-inflammatory and anti-proliferative responses through a ROS-independent mechanism.
PubMed:	The effects of tetrahydrocurcumin and green tea polyphenol on the survival of male C57BL/6 mice.
PubMed:	Comparative cytotoxicity and ROS generation by curcumin and tetrahydrocurcumin following visible-light irradiation or treatment with horseradish peroxidase.
PubMed:	Effect of tetrahydrocurcumin on plasma antioxidants in streptozotocin-nicotinamide experimental diabetes.
PubMed:	What really declines with age? The Hayflick Lecture for 2006 35th American Aging Association.
PubMed:	Changes in glycoprotein components in streptozotocin--nicotinamide induced type 2 diabetes: influence of tetrahydrocurcumin from Curcuma longa.
PubMed:	Comparative antioxidant activities of curcumin and its demethoxy and hydrogenated derivatives.
PubMed:	Curcumin induces pro-apoptotic endoplasmic reticulum stress in human leukemia HL-60 cells.
PubMed:	Tetrahydrocurcumin: effect on chloroquine-mediated oxidative damage in rat kidney.
PubMed:	Comparison of systemic availability of curcumin with that of curcumin formulated with phosphatidylcholine.
PubMed:	Modulation of function of three ABC drug transporters, P-glycoprotein (ABCB1), mitoxantrone resistance protein (ABCG2) and multidrug resistance protein 1 (ABCC1) by tetrahydrocurcumin, a major metabolite of curcumin.
PubMed:	Effect of tetrahydrocurcumin on lipid peroxidation and lipids in streptozotocin-nicotinamide-induced diabetic rats.
PubMed:	Antioxidant effect of tetrahydrocurcumin in streptozotocin-nicotinamide induced diabetic rats.
PubMed:	Curcumin is an inhibitor of p300 histone acetylatransferase.
PubMed:	Effect of tetrahydrocurcumin on blood glucose, plasma insulin and hepatic key enzymes in streptozotocin induced diabetic rats.
PubMed:	Validated LC/MS/MS assay for curcumin and tetrahydrocurcumin in rat plasma and application to pharmacokinetic study of phospholipid complex of curcumin.
PubMed:	Effect of tetrahydrocurcumin on erythromycin estolate-induced lipid peroxidation in rats.
PubMed:	Elucidation of anti-allergic activities of curcumin-related compounds with a special reference to their anti-oxidative activities.
PubMed:	Tetrahydrocurcumin in plasma and urine: quantitation by high performance liquid chromatography.
PubMed:	Protective role of antioxidative food factors in oxidative stress caused by hyperglycemia.
PubMed:	Relationship between intracellular ROS production and membrane mobility in curcumin- and tetrahydrocurcumin-treated human gingival fibroblasts and human submandibular gland carcinoma cells.
PubMed:	Protective role of tetrahydrocurcumin (THC) an active principle of turmeric on chloroquine induced hepatotoxicity in rats.
PubMed:	Suppression of protein kinase C and nuclear oncogene expression as possible action mechanisms of cancer chemoprevention by Curcumin.
PubMed:	Hydrogen-bonding and C-H...pi interactions in 1,7-bis(4-hydroxy-3-methoxyphenyl)heptane-3,5-dione (tetrahydrocurcumin).
PubMed:	Interventions in aging and age-associated pathologies by means of nutritional approaches.
PubMed:	Modulation of arachidonic acid metabolism by curcumin and related beta-diketone derivatives: effects on cytosolic phospholipase A(2), cyclooxygenases and 5-lipoxygenase.
PubMed:	Protective role of tetrahydrocurcumin against erythromycin estolate-induced hepatotoxicity.
PubMed:	Involvement of multidrug resistance-associated proteins in regulating cellular levels of (-)-epigallocatechin-3-gallate and its methyl metabolites.
PubMed:	Contact allergy to tetrahydrocurcumin.
PubMed:	Studies on the role of some synthetic curcuminoid derivatives in the inhibition of tumour specific angiogenesis.
PubMed:	The protective effects of tetrahydrocurcumin on oxidative stress in cholesterol-fed rabbits.
PubMed:	Metabolism of the cancer chemopreventive agent curcumin in human and rat intestine.
PubMed:	Curcumin and especially tetrahydrocurcumin ameliorate oxidative stress-induced renal injury in mice.
PubMed:	Mechanisms of cancer chemoprevention by curcumin.
PubMed:	Recent studies on the biofunctions and biotransformations of curcumin.
PubMed:	Characterization of metabolites of the chemopreventive agent curcumin in human and rat hepatocytes and in the rat in vivo, and evaluation of their ability to inhibit phorbol ester-induced prostaglandin E2 production.
PubMed:	Comparative studies on the suppression of nitric oxide synthase by curcumin and its hydrogenated metabolites through down-regulation of IkappaB kinase and NFkappaB activation in macrophages.
PubMed:	Inhibition of radiation-induced lipid peroxidation by tetrahydrocurcumin: possible mechanisms by pulse radiolysis.
PubMed:	Chemoprevention by curcumin during the promotion stage of tumorigenesis of mammary gland in rats irradiated with gamma-rays.
PubMed:	Biotransformation of curcumin through reduction and glucuronidation in mice.
PubMed:	Inhibitory effects of curcumin and tetrahydrocurcuminoids on the tumor promoter-induced reactive oxygen species generation in leukocytes in vitro and in vivo.
PubMed:	Chemopreventive effects of carotenoids and curcumins on mouse colon carcinogenesis after 1,2-dimethylhydrazine initiation.
PubMed:	Involvement of the beta-diketone moiety in the antioxidative mechanism of tetrahydrocurcumin.
PubMed:	Effects of curcumin, demethoxycurcumin, bisdemethoxycurcumin and tetrahydrocurcumin on 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion.
PubMed:	The metabolism and excretion of curcumin (1,7-bis-(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione) in the rat.