geranyl geraniol
tetraprenol
 
Notes:
activates platelets via stimulation of phospholipase a2.
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CAS Number: 7614-21-3Picture of molecule3D/inchi
FDA UNII: AIA02AJA3A
Nikkaji Web: J31.341F
Beilstein Number: 1913779
XlogP3-AA: 6.60 (est)
Molecular Weight: 290.49018000
Formula: C20 H34 O
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome or firefox)
Category: natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Boiling Point: 397.10 °C. @ 760.00 mm Hg (est)
Flash Point: 263.00 °F. TCC ( 128.30 °C. ) (est)
logP (o/w): 7.350 (est)
Soluble in:
 water, 0.005864 mg/L @ 25 °C (est)
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
 None found
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: natural substances and extractives
Recommendation for geranyl geraniol usage levels up to:
 not for fragrance use.
 
Recommendation for geranyl geraniol flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 5281365
National Institute of Allergy and Infectious Diseases: Data
 (2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-ol
Chemidplus: 0007614213
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References:
 (2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-ol
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 5281365
Pubchem (sid): 135021685
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEBI: View
CHEMBL: View
KEGG (GenomeNet): C09094
HMDB (The Human Metabolome Database): Search
FooDB: FDB001528
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 flax
Search Trop  Picture
 flax seed
Search Trop  Picture
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Synonyms:
 geranylgeraniol
(E,E,E)-geranylgeraniol
2,6,10,14-hexadecatetraen-1-ol, 3,7,11,15-tetramethyl-, (2E,6E,10E)-
3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraen-1-ol
(2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-ol
 tetraprenol
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Articles:
PubMed: Overproduction of geranylgeraniol in Coprinopsis cinerea by the expression of geranylgeranyl diphosphate synthase gene.
PubMed: Geranylgeraniol suppresses the viability of human DU145 prostate carcinoma cells and the level of HMG CoA reductase.
PubMed: Chemoprevention of hepatocarcinogenesis with dietary isoprenic derivatives: cellular and molecular aspects.
PubMed: Mevalonate depletion mediates the suppressive impact of geranylgeraniol on murine B16 melanoma cells.
PubMed: Geranylgeraniol and beta-ionone inhibit hepatic preneoplastic lesions, cell proliferation, total plasma cholesterol and DNA damage during the initial phases of hepatocarcinogenesis, but only the former inhibits NF-kappaB activation.
PubMed: Dual action of isoprenols from herbal medicines on both PPARgamma and PPARalpha in 3T3-L1 adipocytes and HepG2 hepatocytes.
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