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Category: cosmetic agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Boiling Point: | 447.28 °C. @ 760.00 mm Hg (est)
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| Flash Point: | 365.00 °F. TCC ( 185.00 °C. ) (est)
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| logP (o/w): | 1.300 |
| Soluble in: |
| | water, 1.319e+004 mg/L @ 25 °C (est) |
Organoleptic Properties:
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-mouse LD50 5810 mg/kg "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 668, 1986.
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | cosmetic agents |
| Recommendation for ethyl gallate usage levels up to: | | | not for fragrance use.
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| Recommendation for ethyl gallate flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | benzoic acid, 3,4,5-trihydroxy-, ethyl ester | | | ethyl 3,4,5-trihydroxybenzoate | | | ethyl-3,4,5-trihydroxybenzoate | | | ethylgallate | | | gallic acid ethyl ester | | | gallic acid, ethyl ester | | | nipa no. 48 | | | nipagallin A | | | phyllemblin | | | progallin A | | 3,4,5- | trihydroxybenzoic acid ethyl ester |
Articles:
| PubMed: | Antimicrobial activities of various fractions of longan (Dimocarpus longan Lour. Fen Ke) seed extract. |
| PubMed: | Simultaneous detection of green tea catechins and gallic acid in human serum after ingestion of green tea tablets using ion-pair high-performance liquid chromatography with electrochemical detection. |
| PubMed: | Synthesis, biological evaluation and docking studies of 4-aryloxymethyl coumarins derived from substructures and degradation products of vancomycin. |
| PubMed: | Ethyl gallate attenuates acute lung injury through Nrf2 signaling. |
| PubMed: | Looking like Limulus? - Retinula axons and visual neuropils of the median and lateral eyes of scorpions. |
| PubMed: | [Phenolic constituents of Ampelopsis grossedentata from zhangjiajie]. |
| PubMed: | [Study on chemical constituents from flowers of Ailanthus altissima]. |
| PubMed: | Protective effect of Paeonia anomala extracts and constituents against tert-butylhydroperoxide-induced oxidative stress in HepG2 cells. |
| PubMed: | Glyoxal and methylglyoxal: autoxidation from dihydroxyacetone and polyphenol cytoprotective antioxidant mechanisms. |
| PubMed: | Ethyl Gallate Induces Apoptosis of HL-60 Cells by Promoting the Expression of Caspases-8, -9, -3, Apoptosis-Inducing Factor and Endonuclease G. |
| PubMed: | [Phenolic acid derivatives from Alchornea trewioides]. |
| PubMed: | Synergy study of the inhibitory potential of red wine polyphenols on vascular smooth muscle cell proliferation. |
| PubMed: | Identifying new lignin bioengineering targets: impact of epicatechin, quercetin glycoside, and gallate derivatives on the lignification and fermentation of maize cell walls. |
| PubMed: | Antibacterial activity of wine phenolic compounds and oenological extracts against potential respiratory pathogens. |
| PubMed: | Free radical scavenging, cytotoxic, and hemolytic activities of an active antioxidant compound ethyl gallate from leaves of Acacia nilotica (L.) Wild. Ex. Delile subsp. indica (Benth.) Brenan. |
| PubMed: | Tannic acid inhibited norovirus binding to HBGA receptors, a study of 50 Chinese medicinal herbs. |
| PubMed: | Bioactive constituents from Harpephyllum caffrum Bernh. and Rhus coriaria L. |
| PubMed: | Gallic treatment is galling to Pseudomonas. |
| PubMed: | Mechanisms of systemic vasodilation by lysozyme-c in septic shock. |
| PubMed: | [Chemical constituents from the roots of Pithecellobium lucidum and their cytotoxic activity]. |
| PubMed: | Benefits of ethyl gallate versus norepinephrine in the treatment of cardiovascular collapse in Pseudomonas aeruginosa septic shock in dogs. |
| PubMed: | [Phenolic acid derivatives from Bauhinia glauca subsp. pernervosa]. |
| PubMed: | Involvement of heme oxygenase-1 induction in inhibitory effect of ethyl gallate isolated from Galla Rhois on nitric oxide production in RAW 264.7 macrophages. |
| PubMed: | Ethyl gallate isolated from Pistacia integerrima Linn. inhibits cell adhesion molecules by blocking AP-1 transcription factor. |
| PubMed: | [Study on the chemical constituents from fresh roots of Euphorbia fischeriana]. |
| PubMed: | Revisiting the anatomy of the central nervous system of a hemimetabolous model insect species: the pea aphid Acyrthosiphon pisum. |
| PubMed: | Ethyl gallate, a scavenger of hydrogen peroxide that inhibits lysozyme-induced hydrogen peroxide signaling in vitro, reverses hypotension in canine septic shock. |
| PubMed: | Partial least squares and principal components analysis of wine vintage by high performance liquid chromatography with chemiluminescence detection. |
| PubMed: | [Chemical constituents from stem barks of Vernonia cumingiana]. |
| PubMed: | Cell death shapes embryonic lineages of the central complex in the grasshopper Schistocerca gregaria. |
| PubMed: | Sexual dimorphism in shape and distribution of GABA-like immuno-reactive neurons in cricket terminal abdominal ganglion. |
| PubMed: | Chemical changes during fermentation of Abhayarishta and its standardization by HPLC-DAD. |
| PubMed: | In vitro drug interactions of gallates with antibiotics in Staphylococcus Aureus. |
| PubMed: | [Chemical constituents from roots of Distylium myricoides]. |
| PubMed: | LC-MS/MS method for the simultaneous determination of ethyl gallate and its major metabolite in rat plasma. |
| PubMed: | Constancy and variability of identified glomeruli in antennal lobes: computational approach in Spodoptera littoralis. |
| PubMed: | Validated HPLC method for the standardization of Phyllanthus niruri (herb and commercial extracts) using corilagin as a phytochemical marker. |
| PubMed: | [Studies on chemical constituents from leaves of Lysidice brevicalyx]. |
| PubMed: | [Studies on chemical constituents of Salacia prinoides]. |
| PubMed: | A redetermination of 2-(6-diethyl-amino-3-diethyl-iminio-3H-xanthen-9-yl)benzoate-ethyl gallate (1/1) at room temperature. |
| PubMed: | Antioxidant constituents of Nymphaea caerulea flowers. |
| PubMed: | Antiplasmodial phenolic compounds from Piptadenia pervillei. |
| PubMed: | Recognition and incision of Cr(III) ligand-conjugated DNA adducts by the nucleotide excision repair proteins UvrABC: importance of the Cr(III)-purine moiety in the enzymatic reaction. |
| PubMed: | A new benzofuranic acid from the leaves of Rhus alata. |
| PubMed: | A low-temperature phase of the 1:1 complex of 2-(6-diethylamino-3-diethyl-iminio-3H-xanthen-9-yl)benzoate with ethyl gallate at 93 K. |
| PubMed: | A major ingredient of green tea rescues mice from lethal sepsis partly by inhibiting HMGB1. |
| PubMed: | Antioxidant activity of brocchlin carboxylic acid and its methyl ester from Chrozophora brocchiana. |
| PubMed: | Antibacterial phenolic compounds from the spines of Gleditsia sinensis Lam. |
| PubMed: | [Chemical constitutents of Bauhinia aurea]. |
| PubMed: | Phosphodiesterase-I inhibitor quinovic acid glycosides from Bridelia ndellensis. |
| PubMed: | Isolation of the active compound in Mauria heterophylla, a Peruvian plant with antibacterial activity. |
| PubMed: | Effects of structure on radical-scavenging abilities and antioxidative activities of tea polyphenols: NMR analytical approach using 1,1-diphenyl-2-picrylhydrazyl radicals. |
| PubMed: | Alkyl gallates, intensifiers of beta-lactam susceptibility in methicillin-resistant Staphylococcus aureus. |
| PubMed: | Biological activity of phenolic compounds from Alchornea glandulosa. |
| PubMed: | [Studies on the chemical constituents of Ampelopsis humulifolia var. heterophylla (Thunb.) K. Koch]. |
| PubMed: | Antioxidant flavonoids and phenolic acids from leaves of Leea guineense G Don (Leeaceae). |
| PubMed: | Two new and four known polyphenolics obtained as new cell-cycle inhibitors from Rubus aleaefolius Poir. |
| PubMed: | GC-mS analysis and anti-microbial activity of acidic fractions obtained from Paeonia peregrina and Paeonia tenuifolia roots. |
| PubMed: | Inhibition of cancer cell growth by crude extract and the phenolics of Terminalia chebula retz. fruit. |
| PubMed: | Pharmacologically active ellagitannins from Terminalia myriocarpa. |
| PubMed: | Deodorizing effects of tea catechins on amines and ammonia. |
| PubMed: | Analytical method of measuring tea catechins in human plasma by solid-phase extraction and HPLC with electrochemical detection. |
| PubMed: | Ethyl m-digallate from red maple, Acer rubrum L., as the major resistance factor to forest tent caterpillar, Malacosoma disstria Hbn. |
| PubMed: | Free radical lipid peroxidation inhibits enzymatic conversion of beta-carotene into vitamin A. |
| PubMed: | [Effect of gallic acid derivatives on secretion of Th1 cytokines and Th2 cytokines from anti CD3-stimulated spleen cells]. |
| PubMed: | Isolation and characterization of novel benzoates, cinnamates, flavonoids, and lignans from Riesling wine and screening for antioxidant activity. |
| PubMed: | [Polyphenol compounds from Hamamelis virginiana L]. |
| PubMed: | NMR Analytical Approach To Clarify the Antioxidative Molecular Mechanism of Catechins Using 1,1-Diphenyl-2-picrylhydrazyl. |
| PubMed: | NMR analytical approach to clarify the molecular mechanisms of the antioxidative and radical-scavenging activities of antioxidants in tea using 1,1-diphenyl-2-picrylhydrazyl. |
| PubMed: | A novel beta-glucuronidase inhibiting triterpenoid from Paeonia emodi. |
| PubMed: | Potent and selective inhibition of squalene epoxidase by synthetic galloyl esters. |
| PubMed: | The mechanisms underlying the relaxant effect of methyl and ethyl gallates in the guinea pig trachea in vitro: contribution of potassium channels. |
| PubMed: | Gallates inhibit cytokine-induced nuclear translocation of NF-kappaB and expression of leukocyte adhesion molecules in vascular endothelial cells. |
| PubMed: | Evidence of Trolox and some gallates as synergistic protectors of erythrocytes against peroxyl radicals. |
| PubMed: | Modular structures in the mushroom body of the cockroach. |
| PubMed: | Extraction and purification of effective antimicrobial constituents of Terminalia chebula RETS. against methicillin-resistant Staphylococcus aureus. |
| PubMed: | Antineoplastic agents 338. The cancer cell growth inhibitory. Constituents of Terminalia arjuna (Combretaceae). |
| PubMed: | Morphology of neuroglia in the antennal lobes and mushroom bodies of the brain of the honeybee. |
| PubMed: | Neuroanatomy of a crayfish thoracic ganglion: sensory and motor roots of the walking-leg nerves and possible homologies with insects. |
| PubMed: | [Chemical constituents of roots of Ampelopsis brevipedunculata (Maxim) Trautv]. |
| PubMed: | Cytotoxicity of propyl gallate and related compounds in rat hepatocytes. |
| PubMed: | Testing of lipoxygenase inhibitors, cyclooxygenase inhibitors, drugs with immunomodulating properties and some reference antipsoriatic drugs in the modified mouse tail test, an animal model of psoriasis. |
| PubMed: | Organization of the commissural fibers in the adult brain of the locust. |
| PubMed: | Structural organization of male-specific visual neurons in calliphorid optic lobes. |
| PubMed: | Depigmentation and inhibition of cell growth of B-16 melanoma cells by compounds isolated from Paeonia suffruticosa callus. |
| PubMed: | The osmium-ethyl gallate procedure is superior to silver impregnations for mapping neuronal pathways. |
| PubMed: | The structure of the fourth abdominal ganglion of the crayfish, Procambarus clarki (Girard). I. Tracts in the ganglionic core. |
| PubMed: | Identifiable neurons in the locust central nervous system that react with antibodies to serotonin. |
| PubMed: | Influence of pH and light on the stability of some antioxidants. |
| PubMed: | Lipid staining for the electron microscope: a new method. |
| PubMed: | THE USE OF THE OSMIUM-ETHYL GALLATE TECHNIQUE IN THE STUDY OF CARBON TETRACHLORIDE LIVER INJURY. |
| PubMed: | Bacteriostatic, bactericidal, and drug resistance studies of ethyl gallate on Mycobacterium tuberculosis. |
| PubMed: | Physiological suitability of ethyl gallate as an anti-oxidant. II. The determination of chronic toxicity. |
| PubMed: | Physiological suitability of ethyl gallate as an anti-oxidant. I. Acute toxicity dose. |
| PubMed: | Ethyl gallate, a mycobacteria-specific antibiotic isolated from Haematoxylon campechianum. II. Microbiological studies. |
| PubMed: | Ethyl gallate, a mycobacteria-specific antibiotic isolated from Haematoxylon campechianum. I. Isolation and chemical studies. |
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