| PubMed: | Limonoids and flavonoids from the flowers of Azadirachta indica var. siamensis, and their melanogenesis-inhibitory and cytotoxic activities. |
| PubMed: | Inhibition of human cytochrome P450 enzymes by hops (Humulus lupulus) and hop prenylphenols. |
| PubMed: | Herbal preparations for the menopause: beyond isoflavones and black cohosh. |
| PubMed: | Analytical methods for quantitation of prenylated flavonoids from hops. |
| PubMed: | Chroman-like cyclic prenylflavonoids promote neuronal differentiation and neurite outgrowth and are neuroprotective. |
| PubMed: | [Comparative study on effect of 8-prenlynaringenin and narigenin on activity of osteoclasts cultured in vitro]. |
| PubMed: | Interaction of prenylated chalcones and flavanones from common hop with phosphatidylcholine model membranes. |
| PubMed: | Human pharmacokinetics of xanthohumol, an antihyperglycemic flavonoid from hops. |
| PubMed: | Microbial sulfation of 8-prenylnaringenin. |
| PubMed: | Evaluation of estrogenic activity of licorice species in comparison with hops used in botanicals for menopausal symptoms. |
| PubMed: | Effect of xanthohumol and 8-prenylnaringenin on MCF-7 breast cancer cells oxidative stress and mitochondrial complexes expression. |
| PubMed: | Beer and beer compounds: physiological effects on skin health. |
| PubMed: | Simultaneous determination of prenylflavonoid and hop bitter acid in beer lee by HPLC-DAD-MS. |
| PubMed: | [Inhibitory effect of 8-prenylnaringenin on osteoclastogensis of bone marrow cells and bone resorption activity]. |
| PubMed: | Analytical condition setting a crucial step in the quantification of unstable polyphenols in acidic conditions: analyzing prenylflavanoids in biological samples by liquid chromatography-electrospray ionization triple quadruple mass spectrometry. |
| PubMed: | Phytoestrogens in menopausal supplements induce ER-dependent cell proliferation and overcome breast cancer treatment in an in vitro breast cancer model. |
| PubMed: | Hop extracts and hop substances in treatment of menopausal complaints. |
| PubMed: | Differential regulation of detoxification enzymes in hepatic and mammary tissue by hops (Humulus lupulus) in vitro and in vivo. |
| PubMed: | Method development and validation for ultra-high-pressure LC/MS/MS determination of hop prenylflavonoids in human serum. |
| PubMed: | The prenyl group contributes to activities of phytoestrogen 8-prenynaringenin in enhancing bone formation and inhibiting bone resorption in vitro. |
| PubMed: | A comparison of the anticancer properties of isoxanthohumol and 8-prenylnaringenin using in vitro models of colon cancer. |
| PubMed: | Comparison between 8-prenylnarigenin and narigenin concerning their activities on promotion of rat bone marrow stromal cells' osteogenic differentiation in vitro. |
| PubMed: | Antiproliferative activity and synthesis of 8-prenylnaringenin derivatives by demethylation of 7-O- and 4'-O-substituted isoxanthohumols. |
| PubMed: | Prevention of disuse muscle atrophy by dietary ingestion of 8-prenylnaringenin in denervated mice. |
| PubMed: | Transformation of 8-prenylnaringenin by Absidia coerulea and Beauveria bassiana. |
| PubMed: | The influence of 8-prenylnaringenin on the activity of voltage-gated Kv1.3 potassium channels in human Jurkat T cells. |
| PubMed: | The phytoestrogen 8-prenylnaringenin inhibits agonist-dependent activation of human platelets. |
| PubMed: | Effect of 17β-estradiol and flavonoids on the regulation of expression of newly identified oestrogen responsive genes in a rat raphe nuclei-derived cell line. |
| PubMed: | Xanthohumol, a prenylated chalcone derived from hops, suppresses cancer cell invasion through inhibiting the expression of CXCR4 chemokine receptor. |
| PubMed: | Hops (Humulus lupulus) inhibits oxidative estrogen metabolism and estrogen-induced malignant transformation in human mammary epithelial cells (MCF-10A). |
| PubMed: | Production of monoclonal antibodies against hop-derived (Humulus lupulus L.) prenylflavonoids and the development of immunoassays. |
| PubMed: | Production of 8-prenylnaringenin from isoxanthohumol through biotransformation by fungi cells. |
| PubMed: | Biotransformation of the phytoestrogen 8-prenylnaringenin. |
| PubMed: | Quantification of xanthohumol, isoxanthohumol, 8-prenylnaringenin, and 6-prenylnaringenin in hop extracts and derived capsules using secondary standards. |
| PubMed: | The prenylflavonoid phytoestrogens 8-prenylnaringenin and isoxanthohumol diferentially suppress steroidogenesis in rat Leydig cells in ontogenesis. |
| PubMed: | Inhibitors of hyaluronan export from hops prevent osteoarthritic reactions. |
| PubMed: | Angiogenesis and inflammation signaling are targets of beer polyphenols on vascular cells. |
| PubMed: | 8-Prenylnaringenin is an inhibitor of multidrug resistance-associated transporters, P-glycoprotein and MRP1. |
| PubMed: | Disposition of hop prenylflavonoids in human breast tissue. |
| PubMed: | Activation of transgenic estrogen receptor-beta by selected phytoestrogens in a stably transduced rat serotonergic cell line. |
| PubMed: | Recovery and metabolism of xanthohumol in germ-free and human microbiota-associated rats. |
| PubMed: | Development of a high-throughput LC/APCI-MS method for the determination of thirteen phytoestrogens including gut microbial metabolites in human urine and serum. |
| PubMed: | A randomized, double-blind, placebo-controlled, cross-over pilot study on the use of a standardized hop extract to alleviate menopausal discomforts. |
| PubMed: | Xanthohumol inhibits IL-12 production and reduces chronic allergic contact dermatitis. |
| PubMed: | Cosupplementation of isoflavones, prenylflavonoids, and lignans alters human exposure to phytoestrogen-derived 17beta-estradiol equivalents. |
| PubMed: | Modulation of aflatoxin B1-mediated genotoxicity in primary cultures of human hepatocytes by diindolylmethane, curcumin, and xanthohumols. |
| PubMed: | Prenylation has a compound specific effect on the estrogenicity of naringenin and genistein. |
| PubMed: | Anti-inflammatory and vascularprotective properties of 8-prenylapigenin. |
| PubMed: | Flavonoid-induced autophagy in hormone sensitive breast cancer cells. |
| PubMed: | Oestrogenicity of prenylflavonoids from hops: activation of pro-oestrogens by intestinal bacteria. |
| PubMed: | Dynamic residual complexity of natural products by qHNMR: solution stability of desmethylxanthohumol. |
| PubMed: | 8-Prenylnaringenin inhibits epidermal growth factor-induced MCF-7 breast cancer cell proliferation by targeting phosphatidylinositol-3-OH kinase activity. |
| PubMed: | Microbial metabolites of 8-prenylnaringenin, an estrogenic prenylflavanone. |
| PubMed: | Time dependency of uterine effects of naringenin type phytoestrogens in vivo. |
| PubMed: | Direct determination of the estrogenic compounds 8-prenylnaringenin, zearalenone, alpha- and beta-zearalenol in beer by liquid chromatography-mass spectrometry. |
| PubMed: | In vivo estrogenic comparisons of Trifolium pratense (red clover) Humulus lupulus (hops), and the pure compounds isoxanthohumol and 8-prenylnaringenin. |
| PubMed: | Eubacterium limosum activates isoxanthohumol from hops (Humulus lupulus L.) into the potent phytoestrogen 8-prenylnaringenin in vitro and in rat intestine. |
| PubMed: | Comparison of the phytohormones genistein, resveratrol and 8-prenylnaringenin as agents for preventing osteoporosis. |
| PubMed: | Effects of long-term treatment with 8-prenylnaringenin and oral estradiol on the GH-IGF-1 axis and lipid metabolism in rats. |
| PubMed: | Determination of phytoestrogens in dietary supplements by LC-MS/MS. |
| PubMed: | Pharmacognostic and pharmacological profile of Humulus lupulus L. |
| PubMed: | Development of a screening assay for ligands to the estrogen receptor based on magnetic microparticles and LC-MS. |
| PubMed: | Cloning and characterization of naringenin 8-prenyltransferase, a flavonoid-specific prenyltransferase of Sophora flavescens. |
| PubMed: | Aromatase inhibition by synthetic lactones and flavonoids in human placental microsomes and breast fibroblasts--a comparative study. |
| PubMed: | Screening of synthetic and plant-derived compounds for (anti)estrogenic and (anti)androgenic activities. |
| PubMed: | Inhibition of topoisomerase I activity and efflux drug transporters' expression by xanthohumol. from hops. |
| PubMed: | Treatment of PC-3 and DU145 prostate cancer cells by prenylflavonoids from hop (Humulus lupulus L.) induces a caspase-independent form of cell death. |
| PubMed: | Ability of prenylflavanones present in hops to induce apoptosis in a human Burkitt lymphoma cell line. |
| PubMed: | 8-Prenylnaringenin, inhibits estrogen receptor-alpha mediated cell growth and induces apoptosis in MCF-7 breast cancer cells. |
| PubMed: | Modulation of breast cancer cell survival by aromatase inhibiting hop (Humulus lupulus L.) flavonoids. |
| PubMed: | Effects of the chemically synthesized flavanone 7-(O-prenyl)naringenin-4'-acetate on the estrogen signaling pathway in vivo and in vitro. |
| PubMed: | Binding of the hop (Humulus lupulus L.) chalcone xanthohumol to cytosolic proteins in Caco-2 intestinal epithelial cells. |
| PubMed: | Microbial and dietary factors associated with the 8-prenylnaringenin producer phenotype: a dietary intervention trial with fifty healthy post-menopausal Caucasian women. |
| PubMed: | Metabolism of isoflavones, lignans and prenylflavonoids by intestinal bacteria: producer phenotyping and relation with intestinal community. |
| PubMed: | Resolution of diastereomeric flavonoid (1S)-(-)-camphanic acid esters via reversed-phase HPLC. |
| PubMed: | Antihyperglycemic activity and chemical constituents of Eysenhardtia platycarpa. |
| PubMed: | Subtle side-chain modifications of the hop phytoestrogen 8-prenylnaringenin result in distinct agonist/antagonist activity profiles for estrogen receptors alpha and beta. |
| PubMed: | The hop phytoestrogen, 8-prenylnaringenin, reverses the ovariectomy-induced rise in skin temperature in an animal model of menopausal hot flushes. |
| PubMed: | Microbial metabolism of the prenylated chalcone xanthohumol. |
| PubMed: | Pharmacokinetics and systemic endocrine effects of the phyto-oestrogen 8-prenylnaringenin after single oral doses to postmenopausal women. |
| PubMed: | pH-independent drug release of an extremely poorly soluble weakly acidic drug from multiparticulate extended release formulations. |
| PubMed: | Morphologic changes induced by oral long-term treatment with 8-prenylnaringenin in the uterus, vagina, and mammary gland of castrated rats. |
| PubMed: | The prenylflavonoid isoxanthohumol from hops (Humulus lupulus L.) is activated into the potent phytoestrogen 8-prenylnaringenin in vitro and in the human intestine. |
| PubMed: | In vitro studies of intestinal permeability and hepatic and intestinal metabolism of 8-prenylnaringenin, a potent phytoestrogen from hops (Humulus lupulus L.). |
| PubMed: | Anti-proliferative properties of prenylated flavonoids from hops (Humulus lupulus L.) in human prostate cancer cell lines. |
| PubMed: | Identification of human hepatic cytochrome P450 enzymes involved in the metabolism of 8-prenylnaringenin and isoxanthohumol from hops (Humulus lupulus L.). |
| PubMed: | Effect of hop (Humulus lupulus L.) flavonoids on aromatase (estrogen synthase) activity. |
| PubMed: | Effects of 8-prenylnaringenin on the hypothalamo-pituitary-uterine axis in rats after 3-month treatment. |
| PubMed: | Effects of estrogenic xenobiotics on human and mouse spermatozoa. |
| PubMed: | A first prospective, randomized, double-blind, placebo-controlled study on the use of a standardized hop extract to alleviate menopausal discomforts. |
| PubMed: | Effect of phytoestrogens on gene expression of carbonic anhydrase II in rat uterus and liver. |
| PubMed: | Tissue specificity of 8-prenylnaringenin: protection from ovariectomy induced bone loss with minimal trophic effects on the uterus. |
| PubMed: | Xanthohumol isolated from Humulus lupulus Inhibits menadione-induced DNA damage through induction of quinone reductase. |
| PubMed: | Activation of proestrogens from hops (Humulus lupulus L.) by intestinal microbiota; conversion of isoxanthohumol into 8-prenylnaringenin. |
| PubMed: | Comparison of the in vitro estrogenic activities of compounds from hops (Humulus lupulus) and red clover (Trifolium pratense). |
| PubMed: | Regulation of osteoblastic phenotype and gene expression by hop-derived phytoestrogens. |
| PubMed: | Comparative study of oestrogenic properties of eight phytoestrogens in MCF7 human breast cancer cells. |
| PubMed: | Development of a radioimmunoassay for the quantitative determination of 8-prenylnaringenin in biological matrices. |
| PubMed: | Determination of unusual soya and non-soya phytoestrogen sources in beer, fish products and other foods. |
| PubMed: | Metabolism of xanthohumol and isoxanthohumol, prenylated flavonoids from hops (Humulus lupulus L.), by human liver microsomes. |
| PubMed: | Phytochemical-induced changes in gene expression of carcinogen-metabolizing enzymes in cultured human primary hepatocytes. |
| PubMed: | Estrogens and congeners from spent hops (Humulus lupulus). |
| PubMed: | Naringenin-type flavonoids show different estrogenic effects in mammalian and teleost test systems. |
| PubMed: | Two major metabolites of 8-prenylnaringenin are estrogenic in vitro. |
| PubMed: | Rapid yeast estrogen bioassays stably expressing human estrogen receptors alpha and beta, and green fluorescent protein: a comparison of different compounds with both receptor types. |
| PubMed: | Uterine effects of the phytoestrogen 6-(1,1-dimethylallyl)naringenin in rats. |
| PubMed: | Xanthohumol and related prenylflavonoids from hops and beer: to your good health! |
| PubMed: | Toxicity and cell cycle effects of synthetic 8-prenylnaringenin and derivatives in human cells. |
| PubMed: | 8-prenylnaringenin, a novel phytoestrogen, inhibits angiogenesis in vitro and in vivo. |
| PubMed: | Regulation of gene expression by 8-prenylnaringenin in uterus and liver of Wistar rats. |
| PubMed: | Prediction of ligand binding affinity and orientation of xenoestrogens to the estrogen receptor by molecular dynamics simulations and the linear interaction energy method. |
| PubMed: | Metabolism of 8-prenylnaringenin, a potent phytoestrogen from hops (Humulus lupulus), by human liver microsomes. |
| PubMed: | Antiandrogenic activity of the phytoestrogens naringenin, 6-(1,1-dimethylallyl)naringenin and 8-prenylnaringenin. |
| PubMed: | Phytoestrogens: recent developments. |
| PubMed: | "Bust enhancing" herbal products. |
| PubMed: | 8-Prenyl naringenin is a potent ERalpha selective phytoestrogen present in hops and beer. |
| PubMed: | A binary screening assay for pro-oestrogens in food: metabolic activation using hepatic microsomes and detection with oestrogen sensitive recombinant yeast cells. |
| PubMed: | Analysis of estrogenic activity of foodstuffs and cigarette smoke condensates using a yeast estrogen screening method. |
| PubMed: | Efficient production and capture of 8-prenylnaringenin and leachianone G-biosynthetic intermediates of sophoraflavanone G--by the addition of cork tissue to cell suspension cultures of Sophora flavescens. |
| PubMed: | 17beta-Estradiol and environmental estrogens significantly affect mammalian sperm function. |
| PubMed: | Estrogenic activity of the phytoestrogens naringenin, 6-(1,1-dimethylallyl)naringenin and 8-prenylnaringenin. |
| PubMed: | Oestrogenic activity of the hop phyto-oestrogen, 8-prenylnaringenin. |
| PubMed: | Identification, quantitation and biological activity of phytoestrogens in a dietary supplement for breast enhancement. |
| PubMed: | 8-Prenylnaringenin, the phytoestrogen in hops and beer, upregulates the function of the E-cadherin/catenin complex in human mammary carcinoma cells. |
| PubMed: | The endocrine activities of 8-prenylnaringenin and related hop (Humulus lupulus L.) flavonoids. |
| PubMed: | Prenylflavonoids from hops inhibit the metabolic activation of the carcinogenic heterocyclic amine 2-amino-3-methylimidazo[4, 5-f]quinoline, mediated by cDNA-expressed human CYP1A2. |
| PubMed: | In vitro inhibition of human P450 enzymes by prenylated flavonoids from hops, Humulus lupulus. |
| PubMed: | Determination of the hop-derived phytoestrogen, 8-prenylnaringenin, in beer by gas chromatography/mass spectrometry. |
| PubMed: | Identification of a potent phytoestrogen in hops (Humulus lupulus L.) and beer. |