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Category: natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Boiling Point: | 470.40 °C. @ 760.00 mm Hg (est)
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| Flash Point: | 405.00 °F. TCC ( 207.20 °C. ) (est)
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| logP (o/w): | 7.470 (est) |
| Soluble in: |
| | water, 0.003756 mg/L @ 25 °C (est) |
Organoleptic Properties:
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | natural substances and extractives |
| Recommendation for cannabigerol usage levels up to: | | | not for fragrance use.
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| Recommendation for cannabigerol flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
| | 2-[(2E)-3,7-dimethylocta-2,6-dienyl]-5-pentylbenzene-1,3-diol |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 5315659 |
| Pubchem (sid): | 135115393 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 1,3- | benzenediol, 2-(3,7-dimethyl-2,6-octadienyl)-5-pentyl-, (E)- | | 1,3- | benzenediol, 2-[(2E)-3,7-dimethyl-2,6-octadien-1-yl]-5-pentyl- | | 2-[(2E)-3,7- | dimethyl-2,6-octadien-1-yl]-5-pentyl-1,3-benzenediol | | 2-[(2E)-3,7- | dimethyl-2,6-octadienyl]-5-pentyl-1,3-benzenediol | | 2-[(2E)-3,7- | dimethylocta-2,6-dienyl]-5-pentylbenzene-1,3-diol |
Articles:
| PubMed: | A cannabigerol derivative suppresses immune responses and protects mice from experimental autoimmune encephalomyelitis. |
| PubMed: | Voltage-gated sodium (NaV) channel blockade by plant cannabinoids does not confer anticonvulsant effects per se. |
| PubMed: | Enhancing the activity of cannabidiol and other cannabinoids in vitro through modifications to drug combinations and treatment schedules. |
| PubMed: | Cannabinoid receptor signaling in progenitor/stem cell proliferation and differentiation. |
| PubMed: | The effect of cannabichromene on adult neural stem/progenitor cells. |
| PubMed: | Analysis of cannabis seizures in NSW, Australia: cannabis potency and cannabinoid profile. |
| PubMed: | Epigenetic control of skin differentiation genes by phytocannabinoids. |
| PubMed: | [Marihuana and cannobinoids as medicaments]. |
| PubMed: | Beneficial effect of the non-psychotropic plant cannabinoid cannabigerol on experimental inflammatory bowel disease. |
| PubMed: | Analysis of cannabinoids in laser-microdissected trichomes of medicinal Cannabis sativa using LCMS and cryogenic NMR. |
| PubMed: | Medical use of cannabis. Cannabidiol: a new light for schizophrenia? |
| PubMed: | Effect of chronic exposure to rimonabant and phytocannabinoids on anxiety-like behavior and saccharin palatability. |
| PubMed: | A cannabigerol quinone alleviates neuroinflammation in a chronic model of multiple sclerosis. |
| PubMed: | Cannabinol and cannabidiol exert opposing effects on rat feeding patterns. |
| PubMed: | Cannabinoid hyperemesis syndrome. |
| PubMed: | Modulation of L-α-lysophosphatidylinositol/GPR55 mitogen-activated protein kinase (MAPK) signaling by cannabinoids. |
| PubMed: | Phytocannabinoids as novel therapeutic agents in CNS disorders. |
| PubMed: | Bioactive prenylogous cannabinoid from fiber hemp (Cannabis sativa). |
| PubMed: | Molecular analysis of genetic fidelity in Cannabis sativa L. plants grown from synthetic (encapsulated) seeds following in vitro storage. |
| PubMed: | Plasma and brain pharmacokinetic profile of cannabidiol (CBD), cannabidivarine (CBDV), Δ⁹-tetrahydrocannabivarin (THCV) and cannabigerol (CBG) in rats and mice following oral and intraperitoneal administration and CBD action on obsessive-compulsive behaviour. |
| PubMed: | Nonpsychotropic cannabinoids, abnormal cannabidiol and canabigerol-dimethyl heptyl, act at novel cannabinoid receptors to reduce intraocular pressure. |
| PubMed: | Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects. |
| PubMed: | Cannabinoid actions at TRPV channels: effects on TRPV3 and TRPV4 and their potential relevance to gastrointestinal inflammation. |
| PubMed: | Evaluation of the cyclooxygenase inhibiting effects of six major cannabinoids isolated from Cannabis sativa. |
| PubMed: | Interaction between non-psychotropic cannabinoids in marihuana: effect of cannabigerol (CBG) on the anti-nausea or anti-emetic effects of cannabidiol (CBD) in rats and shrews. |
| PubMed: | Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes. |
| PubMed: | Detection of cannabigerol and its presumptive metabolite in human urine after Cannabis consumption. |
| PubMed: | Antidepressant-like effect of delta9-tetrahydrocannabinol and other cannabinoids isolated from Cannabis sativa L. |
| PubMed: | Cannabinoid receptor 1 binding activity and quantitative analysis of Cannabis sativa L. smoke and vapor. |
| PubMed: | Evidence that the plant cannabinoid cannabigerol is a highly potent alpha2-adrenoceptor agonist and moderately potent 5HT1A receptor antagonist. |
| PubMed: | Innovative development and validation of an HPLC/DAD method for the qualitative and quantitative determination of major cannabinoids in cannabis plant material. |
| PubMed: | Cannabis smoke condensate II: influence of tobacco on tetrahydrocannabinol levels. |
| PubMed: | Antibacterial cannabinoids from Cannabis sativa: a structure-activity study. |
| PubMed: | Plant-derived cannabinoids modulate the activity of transient receptor potential channels of ankyrin type-1 and melastatin type-8. |
| PubMed: | Isolation and characterization of new Cannabis constituents from a high potency variety. |
| PubMed: | Cannabinoids inhibit human keratinocyte proliferation through a non-CB1/CB2 mechanism and have a potential therapeutic value in the treatment of psoriasis. |
| PubMed: | Antitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma. |
| PubMed: | Flavonoid glycosides and cannabinoids from the pollen of Cannabis sativa L. |
| PubMed: | NMR assignments of the major cannabinoids and cannabiflavonoids isolated from flowers of Cannabis sativa. |
| PubMed: | A chemotaxonomic analysis of cannabinoid variation in Cannabis (Cannabaceae). |
| PubMed: | The inheritance of chemical phenotype in Cannabis sativa L. |
| PubMed: | Cannabinoids in clinical practice. |
| PubMed: | Capillary electrochromatography of cannabinoids. |
| PubMed: | Synthesis and cytotoxic effects of deoxy-tomentellin. |
| PubMed: | Boron trifluoride etherate on silica-A modified Lewis acid reagent (VII). Antitumor activity of cannabigerol against human oral epitheloid carcinoma cells. |
| PubMed: | [Gas chromatographic analysis of cannabinoids on tandem columns]. |
| PubMed: | Comparative in vitro metabolism of the cannabinoids. |
| PubMed: | In vitro metabolism of cannabigerol in several mammalian species. |
| PubMed: | A comparison of the ocular and central effects of delta 9-tetrahydrocannabinol and cannabigerol. |
| PubMed: | The inhibitory effects of cannabinoids, the active constituents of Cannabis sativa L. on human and rabbit platelet aggregation. |
| PubMed: | Formation of similar species to carbon monoxide during hepatic microsomal metabolism of cannabidiol on the basis of spectral interaction with cytochrome P-450. |
| PubMed: | Determination and characterization of a cannabinoid receptor in rat brain. |
| PubMed: | Identification of a new chemotype in Cannabis sativa: cannabigerol-dominant plants, biogenetic and agronomic prospects. |
| PubMed: | Cannabinoid inhibition of adenylate cyclase: relative activity of constituents and metabolites of marihuana. |
| PubMed: | Activation of phospholipase A2 by cannabinoids. Lack of correlation with CNS effects. |
| PubMed: | Intraocular pressure, ocular toxicity and neurotoxicity after administration of cannabinol or cannabigerol. |
| PubMed: | Allergenic properties of naturally occurring cannabinoids. |
| PubMed: | Direct antigonadal activity of cannabinoids: suppression of rat granulosa cell functions. |
| PubMed: | Synthesis and antimicrobial activities of certain cannabichromene and cannabigerol related compounds. |
| PubMed: | Intraocular pressure following systemic administration of cannabinoids. |
| PubMed: | On the definition of cannabinoids: botanical? chemical? pharmacological? |
| PubMed: | High-pressure liquid chromatography of cannabis. Quantitative analysis of acidic and neutral cannabinoids. |
| PubMed: | Cannabinoids: influence on neurotransmitter uptake in rat brain synaptosomes. |
| PubMed: | Chemical basis of hashish activity. |
| PubMed: | Cannabigerol monomethyl ether, a new component of hemp. |
| PubMed: | Identification and quantification of cannabinoids in Cannabis sativa L. plants by high performance liquid chromatography-mass spectrometry. |
| PubMed: | Differences in receptor binding affinity of several phytocannabinoids does not explain their effects on neural cell cultures. |
| PubMed: | Colon carcinogenesis is inhibited by the TRPM8 antagonist cannabigerol, a Cannabis-derived non-psychotropic cannabinoid. |
| PubMed: | Neuroprotective Properties of Cannabigerol in Huntington's Disease: Studies in R6/2 Mice and 3-Nitropropionate-lesioned Mice. |
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