ayapin
 
Notes:
None found
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CAS Number: 494-56-4Picture of molecule3D/inchi
FDA UNII: 7Y9JR4973B
Nikkaji Web: J11.816H
XlogP3-AA: 1.70 (est)
Molecular Weight: 190.15462000
Formula: C10 H6 O4
NMR Predictor: Predict (works with chrome or firefox)
Category: natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
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Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents: Search
US Patents: Search
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PubMed: Search
NCBI: Search
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Soluble in:
 water, 2218 mg/L @ 25 °C (est)
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
 None found
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: natural substances and extractives
Recommendation for ayapin usage levels up to:
 not for fragrance use.
 
Recommendation for ayapin flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 3083597
National Institute of Allergy and Infectious Diseases: Data
 [1,3]dioxolo[4,5-g]chromen-6-one
Chemidplus: 0000494564
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References:
 [1,3]dioxolo[4,5-g]chromen-6-one
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 3083597
Pubchem (cas): 494-56-4
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEBI: View
CHEMBL: View
KEGG (GenomeNet): C18078
HMDB (The Human Metabolome Database): Search
FooDB: FDB001439
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 sunflower root
Search Trop  Picture
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Synonyms:
6H-1,3-dioxolo(4,5-g)(1)benzopyran-6-one
[1,3]dioxolo[4,5-g]chromen-6-one
6,7-(methylene dioxy) coumarin
6,7-(methylenedioxy)coumarin
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Articles:
PubMed: [Study on distributed patterns of scoparone and ayapin in Dendrobium species from Yunnan].
PubMed: Huperzine A for mild cognitive impairment.
PubMed: [Aromatic constituents of Heteroplexis micocephal and their bioactivities].
PubMed: Toward establishing structure-activity relationships for oxygenated coumarins as differentiation inducers of promonocytic leukemic cells.
PubMed: Huperzine A for vascular dementia.
PubMed: Antifungal activity of a new phenolic compound from capitulum of a head rot-resistant sunflower genotype.
PubMed: Simultaneous analysis of trans- and cis-isomers of 2-glucosyloxycinnamic acids and coumarin derivatives in Dendrobium thyrsiflorum by high-performance liquid chromatography (HPLC)-photodiode array detection (DAD)-electrospray ionization (ESI)-tandem mass spectrometry (MS).
PubMed: Antifungal activity of some coumarins obtained from species of Pterocaulon (Asteraceae).
PubMed: Yb(OTf)3-catalyzed reactions of 5-alkylidene Meldrum's acids with phenols: one-pot assembly of 3,4-dihydrocoumarins, 4-chromanones, coumarins, and chromones.
PubMed: Diterpenes from Alomia myriadenia (Asteraceae) with cytotoxic and trypanocidal activity.
PubMed: [Studies on the chemical constituents of Dendrobium fimbriatum].
PubMed: Systemic acquired resistance in sunflower (Helianthus annuus L.).
PubMed: Atom economy. Palladium-catalyzed formation of coumarins by addition of phenols and alkynoates via a net C-H insertion.
PubMed: New coumarins from Pterocaulon polystachyum.
PubMed: The metabolism of sunflower phytoalexins ayapin and scopoletin: plant-fungus interactions.
PubMed: [Blood coagulation activity of the Ayapin, (6,7-metilen-dioxy-coumarin) obtained from Alomia fastigiata Benth (Compositae)].
PubMed: ACCUMULATION OF AYAPIN AND SCOPOLIN IN SUNFLOWER PLANTS TREATED WITH 2,4-DICHLOROPHENOXYACETIC ACID.
PubMed: Ayapin, scopoletin and 6,7-dimethoxycoumarin from Dendrobium thyrsiflorum (Reichb. f.).
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