Acetylated vetiver oil should only be used as a fragrance ingredient if produced by methods which give products free from allergens. Such acetylated vetiver oils may be prepared by the following acetylation methods using acetic anhydride:

without catalyst, at a temperature not exceeding 120°C.

with ortho phosphoric acid at room temperature.

with sodium acetate in toluene at reflux temperature.

The first two products can be used in their crude form after the usual procedures, but may be further purified. In the last case, distillation is necessary.

This recommendation is based on test results of RIFM with samples prepared according to different acetylation methods (private communication to IFRA).

Due to the possible ingestion of small amounts of fragrance ingredients from their use in products in Categories 1 and 6, materials must not only comply with IFRA Standards but must also be recognized as safe as a flavoring ingredient as defined by the IOFI Code of Practice (www.iofi.org). For more details see chapter 1 of the Guidance for the use of IFRA Standards.