polygala tenuifolia root extract
extract of the roots of polygala tenuifolia, polygalaceae
 
Notes:
/polygala/ a plant genus of the family polygalaceae that contains onjisaponins, xanthones, pyrones, and benzophenones. the name is similar to other snakeroots such as asarum; sanicula; aristolochia; ageratina; and others.
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Name: polygala tenuifolia root extract
CAS Number: 94167-09-6 
ECHA EC Number: 303-407-4
Category: cosmetic ingredient for skin conditioning
 
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Physical Properties:
Food Chemicals Codex Listed: No
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: skin conditioning
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Suppliers:
AuNutra® Industries
Polygalae Root P.E.
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: cosmetic ingredient for skin conditioning
Recommendation for polygala tenuifolia root extract usage levels up to:
 not for fragrance use.
 
Recommendation for polygala tenuifolia root extract flavor usage levels up to:
 not for flavor use.
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Safety References:
AIDS Citations: Search
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EPA ACToR: Toxicology Data
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National Institute of Allergy and Infectious Diseases: Data
 polygala tenuifolia root extract
Chemidplus: 0094167096
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References:
 polygala tenuifolia root extract
Pubchem (sid): 135321080
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Other Information:
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 polygala tenuifolia root
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Synonyms:
 extract of the roots of polygala tenuifolia, polygalaceae
 polygala rehmannii root extract
 yuan zhi root extract
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Articles:
PubMed: Memory-Enhancing Effects of the Crude Extract of Polygala tenuifolia on Aged Mice.
PubMed: Protective effect of senegenin on splenectomy-induced postoperative cognitive dysfunction in elderly rats.
PubMed: The discovery of Yuanzhi-1, a triterpenoid saponin derived from the traditional Chinese medicine, has antidepressant-like activity.
PubMed: Preclinical evidence of rapid-onset antidepressant-like effect in Radix Polygalae extract.
PubMed: Neuroprotective Effects of 3,6'-Disinapoyl Sucrose Through Increased BDNF Levels and CREB Phosphorylation via the CaMKII and ERK1/2 Pathway.
PubMed: High throughput screening of natural products for anti-mitotic effects in MDA-MB-231 human breast carcinoma cells.
PubMed: The inhibition of JNK MAPK and NF-κB signaling by tenuifoliside A isolated from Polygala tenuifolia in lipopolysaccharide-induced macrophages is associated with its anti-inflammatory effect.
PubMed: Analysis and detection of the chemical constituents of Radix Polygalae and their metabolites in rats after oral administration by ultra high-performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry.
PubMed: Tenuigenin ameliorates learning and memory impairments induced by ovariectomy.
PubMed: Tenuigenin treatment improves behavioral Y-maze learning by enhancing synaptic plasticity in mice.
PubMed: Senegenin attenuates hepatic ischemia-reperfusion induced cognitive dysfunction by increasing hippocampal NR2B expression in rats.
PubMed: Anti-inflammatory effects of Polygala tenuifolia root through inhibition of NF-κB activation in lipopolysaccharide-induced BV2 microglial cells.
PubMed: Effects of the crude extract of Polygala tenuifolia Willd on human sperm in vitro.
PubMed: Neuroprotective effects of tenuigenin in a SH-SY5Y cell model with 6-OHDA-induced injury.
PubMed: Polygalae radix inhibits toxin-induced neuronal death in the Parkinson's disease models.
PubMed: Antioxidant activity of oligosaccharide ester extracted from Polygala tenuifolia roots in senescence-accelerated mice.
PubMed: Anxiolytic and sedative-hypnotic activities of polygalasaponins from Polygala tenuifolia in mice.
PubMed: Antidepressant effects of the extract YZ-50 from Polygala tenuifolia in chronic mild stress treated rats and its possible mechanisms.
PubMed: Polygalasaponin XXXII from Polygala tenuifolia root improves hippocampal-dependent learning and memory.
PubMed: Localization and dynamic change of saponin in vegetative organs of Polygala tenuifolia.
PubMed: BT-11 improves stress-induced memory impairments through increment of glucose utilization and total neural cell adhesion molecule levels in rat brains.
PubMed: Effects of Polygala tenuifolia root extract on proliferation of neural stem cells in the hippocampal CA1 region.
PubMed: Effect of Polygala tenuifolia root extract on scopolamine-induced impairment of rat spatial cognition in an eight-arm radial maze task.
PubMed: Cerebral protective and cognition-improving effects of sinapic acid in rodents.
PubMed: Effect of Polygala tenuifolia root extract on cerebral ischemia and reperfusion.
PubMed: [Studies on the chemical constituents in root bark of Polygala tenuifolia (II)].
PubMed: Attenuation of cocaine-induced conditioned place preference by Polygala tenuifolia root extract.
PubMed: Effect of Polygala tenuifolia root on behavioral disorders by lesioning nucleus basalis magnocellularis in rat.
PubMed: Tenuifoliose Q, a new oligosaccharide ester from the root of Polygala tenuifolia Willd.
PubMed: Induction of NGF synthesis in astrocytes by onjisaponins of Polygala tenuifolia, constituents of kampo (Japanese herbal) medicine, Ninjin-yoei-to.
PubMed: [Studies on chemical constituents of fat oil of Polygala tenuifolia].
PubMed: Novel cognitive improving and neuroprotective activities of Polygala tenuifolia Willdenow extract, BT-11.
PubMed: Onjisaponins, from the root of Polygala tenuifolia Willdenow, as effective adjuvants for nasal influenza and diphtheria-pertussis-tetanus vaccines.
PubMed: Effect of Polygala tenuifolia root extract on the tumor necrosis factor-alpha secretion from mouse astrocytes.
PubMed: [SUGAR COMPONENTS OF THE ROOT OF POLYGALA TENUIFOLIA].
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