starch 2-hydroxyethyl ether
2-hydroxyethyl starch
 
Notes:
a derivative of starch used as a plasma substitute in the treatment of hemorrhage.
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    • BOC Sciences
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      Product(s):
      9005-27-0 Hydroxyethyl starch
       
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CAS Number: 9005-27-0 
Other(deleted CASRN): 115252-32-9
FDA UNII: MOQ3RNM0SV
MDL: MFCD00131356
Category: indirect food additives: adhesives and components of coatings
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
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Google Scholar: with word "volatile"Search
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Google Patents: Search
US Patents: Search
EU Patents: Search
PubMed: Search
NCBI: Search
 FDA/DG SANTE Petitions, Reviews, Notices:
FR DOC # 2012-18110 Risks and Benefits of Hydroxyethyl Starch Solutions; Public Workshop Pages 43601 - 43601 View - petition PDF
DG SANTE Food Contact Materials: 2-hydroxyethyl starch
FDA Mainterm (IAUFC):9005-27-0 ; HYDROXYETHYL STARCH
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
BOC Sciences
For experimental / research use only.
Hydroxyethyl starch
Carbosynth
For experimental / research use only.
Hydroxyethyl starch - 200/0.5
Santa Cruz Biotechnology
For experimental / research use only.
Hydroxyethyl Starch
Sigma-Aldrich: Sigma
For experimental / research use only.
Hydroxyethyl starch
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Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50  > 50000 mg/kg
Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 16, Pg. 431, 1974.

intravenous-rat LD50  8280 mg/kg
Drugs in Japan Vol. -, Pg. 1007, 1995.

intraperitoneal-rat LD50  > 300000 mg/kg
Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 16, Pg. 431, 1974.

intravenous-rabbit LD50  8460 mg/kg
Drugs in Japan Vol. -, Pg. 1007, 1995.

oral-mouse LD50  > 12000 mg/kg
Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 1023, 1972.

intravenous-mouse LD50  20300 mg/kg
BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 1023, 1972.

intraperitoneal-mouse LD50  > 300000 mg/kg
Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 16, Pg. 431, 1974.

Dermal Toxicity:
subcutaneous-rat LD50 > 18000 mg/kg
Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 1023, 1972.

subcutaneous-mouse LD50 > 18000 mg/kg
Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 1023, 1972.

Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: indirect food additives: adhesives and components of coatings
Recommendation for starch 2-hydroxyethyl ether usage levels up to:
 not for fragrance use.
 
Recommendation for starch 2-hydroxyethyl ether flavor usage levels up to:
 not for flavor use.
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Safety References:
ClinicalTrials.gov: search
Daily Med: search
Cancer Citations: Search
Toxicology Citations: Search
EPA Substance Registry Services (TSCA): 9005-27-0
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
Chemidplus: 0009005270
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References:
Canada Domestic Sub. List: 9005-27-0
Pubchem (sid): 135352383
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Other Information:
FDA Indirect Additives used in Food Contact Substances:View
HMDB (The Human Metabolome Database): Search
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
 astro gum 3020
 essex 1360
 essex gum 1360
 ethylex gum 2020
 HES 130/0.4
 hetastarch
2-hydroxyethyl starch
2-hydroxyethyl starch ether
O-(2-hydroxyethyl)starch
 penford 260
 tapioca starch hydroxyethyl ether
 venofundin
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