(Z)-hinokiresinol
phenol, 4,4'-(3-ethenyl-1-propene-1,3-diyl)bis-, (Z)-
 
Notes:
None found
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CAS Number: 79056-22-7Picture of molecule3D/inchi
Nikkaji Web: J1.056.412C
XlogP3-AA: 4.40 (est)
Molecular Weight: 252.31292000
Formula: C17 H16 O2
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Category: natural substances and extractives
 
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Boiling Point: 429.44 °C. @ 760.00 mm Hg (est)
Flash Point: 399.00 °F. TCC ( 203.80 °C. ) (est)
logP (o/w): 3.983 (est)
Soluble in:
 water, 6.587 mg/L @ 25 °C (est)
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
 None found
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: natural substances and extractives
Recommendation for (Z)-hinokiresinol usage levels up to:
 not for fragrance use.
 
Recommendation for (Z)-hinokiresinol flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
AIDS Citations: Search
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EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 6440617
National Institute of Allergy and Infectious Diseases: Data
 4-[(1Z)-3-(4-hydroxyphenyl)penta-1,4-dienyl]phenol
Chemidplus: 0079056227
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References:
 4-[(1Z)-3-(4-hydroxyphenyl)penta-1,4-dienyl]phenol
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 6440617
Pubchem (sid): 135113916
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
HMDB (The Human Metabolome Database): Search
VCF-Online: VCF Volatile Compounds in Food
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Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 found in nature
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Synonyms:
(Z)-4,4'-(3-ethenyl-1-propene-1,3-diyl) bisphenol
cis-hinokiresinol
4-[(1Z)-3-(4-hydroxyphenyl)penta-1,4-dienyl]phenol
 phenol, 4,4'-(3-ethenyl-1-propene-1,3-diyl)bis-, (Z)-
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Articles:
PubMed: Differential anti-ischemic efficacy and therapeutic time window of trans- and cis-hinokiresinols: stereo-specific antioxidant and anti-inflammatory activities.
PubMed: Iridium-catalyzed enantioselective allylic vinylation.
PubMed: Subunit composition of hinokiresinol synthase controls enantiomeric selectivity in hinokiresinol formation.
PubMed: (-)-Nyasol (cis-hinokiresinol), a norneolignan from the rhizomes of Anemarrhena asphodeloides, is a broad spectrum inhibitor of eicosanoid and nitric oxide production.
PubMed: Discriminating the indistinguishable sapwood from heartwood in discolored ancient wood by direct molecular mapping of specific extractives using time-of-flight secondary ion mass spectrometry.
PubMed: The subunit composition of hinokiresinol synthase controls geometrical selectivity in norlignan formation.
PubMed: Antioxidant and antiatherogenic activity of cis-Hinokiresinol from Trapa pseudoincisa.
PubMed: Carroll rearrangement to construct the norneolignan skeleton.
PubMed: Effects of Chamaecyparis formosensis Matasumura extractives on lipopolysaccharide-induced release of nitric oxide.
PubMed: Norlignans with Hyaluronidase Inhibitory Activity from Anemarrhena asphodeloides.
PubMed: Hinokiresinol inhibits IgE-induced mouse passive cutaneous anaphylaxis reaction.
PubMed: Hinokiresinol is not a precursor of agatharesinol in the norlignan biosynthetic pathway in Japanese cedar.
PubMed: Antimalarial and antiplasmodial activities of norneolignans. Syntheses and SAR.
PubMed: Structure and absolute configuration of nyasol and hinokiresinol via synthesis and vibrational circular dichroism spectroscopy.
PubMed: 7-hydroxy-3-(4-hydroxybenzyl)chroman and broussonin b: neurotrophic compounds, isolated from Anemarrhena asphodeloides BUNGE, function as proteasome inhibitors.
PubMed: A heartwood norlignan, (E)-hinokiresinol, is formed from 4-coumaryl 4-coumarate by a Cryptomeria japonica enzyme preparation.
PubMed: Lignans in resin of Araucaria angustifolia by gas chromatography/mass spectrometry.
PubMed: cis-hinokiresinol, a norlignan from Anemarrhena asphodeloides, inhibits angiogenic response in vitro and in vivo.
PubMed: First in vitro norlignan formation with Asparagus officinalis enzyme preparation.
PubMed: Testosterone 5alpha-reductase inhibitory active constituents from Anemarrhenae Rhizoma.
PubMed: Stereochemistry of cis- and trans-hinokiresinol and their estrogen-like activity.
PubMed: Hinokiresinol: a novel inhibitor of LTB4 binding to the human neutrophils.
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