| Name: | azadirachta indica bark extract |
| CAS Number: | 84696-25-3 |
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| ECHA EC Number: | 283-644-7 |
Category: cosmetic ingredient for skin conditioning
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Food Chemicals Codex Listed: | No |
Organoleptic Properties:
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | cosmetic ingredient for skin conditioning |
| Recommendation for azadirachta indica bark extract usage levels up to: | | | not for fragrance use.
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| Recommendation for azadirachta indica bark extract flavor usage levels up to: |
| | not for flavor use.
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Safety References:
| ClinicalTrials.gov: | search |
| Toxicology Citations: | Search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| National Institute of Allergy and Infectious Diseases: | Data |
| | azadirachta indica bark extract |
| Chemidplus: | 0084696253 |
References:
| | azadirachta indica bark extract |
| Pubchem (sid): | 135283160 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | antelaea azadirachta bark extract | | | extract of the bark of the margosa, azadirachta indica, meliaceae | | | margosa bark extract | | | melia indica bark extract | | | neem bark extract (azadirachta indica) |
Articles:
| PubMed: | Feeding Deterrence of Cabbage Looper (Lepidoptera: Noctuidae) by 1-Allyloxy-4-Propoxybenzene, Alone and Blended With Neem Extract. |
| PubMed: | The acaricidal efficacy of aqueous neem extract and ivermectin against Sarcoptes scabiei var. cuniculi in experimentally infested rabbits. |
| PubMed: | The efficacy of neem extract on four microorganisms responsible for causing dental caries viz Streptococcus mutans, Streptococcus salivarius, Streptococcus mitis and Streptococcus sanguis: an in vitro study. |
| PubMed: | Protein-protein and DNA-protein interactions mediate induction of defense genes by fruit extract of Azadirachta indica A. Juss. in Solanum lycopersicum L. |
| PubMed: | Aqueous neem extract versus neem powder on Culex quinquefasciatus: implications for control in anthropogenic habitats. |
| PubMed: | Effect of neem extract against the bacteria isolated from marine fish. |
| PubMed: | Protective effect of Azadirachta indica extract against Eimeria papillata-induced coccidiosis. |
| PubMed: | Gastroprotective effect of Neem (Azadirachta indica) bark extract: possible involvement of H(+)-K(+)-ATPase inhibition and scavenging of hydroxyl radical. |
| PubMed: | Facile green fabrication of nanostructure ZnO plates, bullets, flower, prismatic tip, closed pine cone: Their antibacterial, antioxidant, photoluminescent and photocatalytic properties. |
| PubMed: | Clinical studies on the effect of Neem (Azadirachta indica) bark extract on gastric secretion and gastroduodenal ulcer. |
| PubMed: | Leaf extract of Azadirachta indica (neem): a potential antibiofilm agent for Pseudomonas aeruginosa. |
| PubMed: | How safe is neem extract with respect to thyroid function in male mice? |
| PubMed: | Repellency of the oily extract of neem seeds (Azadirachta indica) against Varroa destructor (Acari: Varroidae). |
| PubMed: | Anti-inflammatory, pro-apoptotic, and anti-proliferative effects of a methanolic neem (Azadirachta indica) leaf extract are mediated via modulation of the nuclear factor-κB pathway. |
| PubMed: | Efficacy of neem extract against the blowfly and housefly. |
| PubMed: | The inhibiting effect of aqueous Azadirachta indica (Neem) extract upon bacterial properties influencing in vitro plaque formation. |
| PubMed: | The effect of mango and neem extract on four organisms causing dental caries: Streptococcus mutans, Streptococcus salivavius, Streptococcus mitis, and Streptococcus sanguis: an in vitro study. |
| PubMed: | Activity-guided isolation and identification of Azadirachta indica bark extract constituents which specifically inhibit chemiluminescence production by activated human polymorphonuclear leukocytes. |
| PubMed: | Ultrastructural alteration of larvae and puparia of blow fly Chrysomya megacephala (F.) (Diptera: Calliphoridae) and house fly Musca domestica L. (Diptera: Muscidae) exposed to neem extract. |
| PubMed: | [Use of neem extract in the control of acariasis by Myobia musculi Schranck (Acari: Miobidae) and Myocoptes musculinus Koch (Acari: Listrophoridae) in mice (Mus musculus var. albina L.)]. |
| PubMed: | The toxic effects of neem extract and azadirachtin on the brown planthopper, Nilaparvata lugens (Stål) (BPH) (Homoptera: Delphacidae). |
| PubMed: | [Activity of neem extract on the embryonary development of Ctenocephalides felis felis (Bouché, 1835) (Siphonaptera: Pulicidae)]. |
| PubMed: | Sexual development of malaria parasites is inhibited in vitro by the neem extract azadirachtin, and its semi-synthetic analogues. |
| PubMed: | Effects of a neem extract on blood feeding, oviposition and oocyte ultrastructure in Anopheles stephensi Liston (Diptera: Culicidae). |
| PubMed: | Evaluation of the acute toxicity to juvenile pacific northwest salmon of azadirachtin, neem extract, and neem-based products. |
| PubMed: | Effect of natural gel product on bovine dentin erosion in vitro. |
| PubMed: | Enhancement of immune responses to neem leaf extract (Azadirachta indica) correlates with antineoplastic activity in BALB/c-mice. |
| PubMed: | Impact of repeated NeemAzal-treated blood meals on the fitness of Anopheles stephensi mosquitoes. |
| PubMed: | Antimutagenic effect of neem leaves extract in freshwater fish, Channa punctatus evaluated by cytogenetic tests. |
| PubMed: | Azadirachta indica attenuates cisplatin-induced nephrotoxicity and oxidative stress. |
| PubMed: | Acute lethal and sublethal effects of neem leaf extract on the neotropical freshwater fish Prochilodus lineatus. |
| PubMed: | Vinegar as a disinfectant of extracted human teeth for dental educational use. |
| PubMed: | Neem-tree (Azadirachta indica Juss.) extract as a feed additive against the American dog tick (Dermacentor variabilis) in sheep (Ovis aries). |
| PubMed: | Effects of neem leaf extract on production of aflatoxins and activities of fatty acid synthetase, isocitrate dehydrogenase and glutathione S-transferase in Aspergillus parasiticus. |
| PubMed: | Effect of neem (Azardirachta indica A. Juss) seeds and leaves extract on some plant pathogenic fungi. |
| PubMed: | A study on antioxidant and apoptotic effect of Azadirachta Indica (neem) in cases of cervical cancer. |
| PubMed: | Effect of aqueous extract from Neem (Azadirachta indica A. Juss) on hydrophobicity, biofilm formation and adhesion in composite resin by Candida albicans. |
| PubMed: | Antibacterial applications of silver nanoparticles synthesized by aqueous extract of Azadirachta indica (Neem) leaves. |
| PubMed: | Evaluation of antiplaque activity of Azadirachta indica leaf extract gel--a 6-week clinical study. |
| PubMed: | Synergistic spermicidal activity of neem seed extract, reetha saponins and quinine hydrochloride. |
| PubMed: | Deleterious activity of natural products on postures of Spodoptera frugiperda (Lepidoptera: Noctuidae) and Diatraea saccharalis (Lepidoptera: Pyralidae). |
| PubMed: | Anticancer effects of ethanolic neem leaf extract on prostate cancer cell line (PC-3). |
| PubMed: | [Control of Ornithonyssus sylviarum (Canestrini and Fanzago, 1877) (Acari: Macronyssidae) infestation in commercial laying hens by using Azadirachta indica extract]. |
| PubMed: | Laboratory evaluation of methanolic extract of Atlantia monophylla (Family: Rutaceae) against immature stages of mosquitoes and non-target organisms. |
| PubMed: | Anti-plasmodial effects of Azadirachta indica in experimental cerebral malaria: Apoptosis of cerebellar Purkinje cells of mice as a marker. |
| PubMed: | Field study on the efficacy of an extract of neem seed (Mite -Stop) against the red mite Dermanyssus gallinae naturally infecting poultry in Egypt. |
| PubMed: | Concurrent administration of aqueous Azadirachta indica (neem) leaf extract with DOCA-salt prevents the development of hypertension and accompanying electrocardiogram changes in the rat. |
| PubMed: | Antioxidative and modifying effects of a tropical plant Azadirachta indica (Neem) on azoxymethane-induced preneoplastic lesions in the rat colon. |
| PubMed: | Azadirachtin interacts with retinoic acid receptors and inhibits retinoic acid-mediated biological responses. |
| PubMed: | Effect of aqueous neem (Azadirachta indica) extract on testosterone and other blood constituents in male rats. A pilot study. |
| PubMed: | Sunlight decreased genotoxicity of azadirachtin on root tip cells of Allium cepa and Eucrosia bicolor. |
| PubMed: | Effect of various mouthwashes on the levels of interleukin-2 and interferon-gamma in chronic gingivitis. |
| PubMed: | Antibacterial, antisecretory and antihemorrhagic activity of Azadirachta indica used to treat cholera and diarrhea in India. |
| PubMed: | The effect of two different dental gels and a mouthwash on plaque and gingival scores: a six-week clinical study. |
| PubMed: | Enhanced Nematicidal Activity of Organic and Inorganic Ammonia-Releasing Amendments by Azadirachta indica Extracts. |
| PubMed: | Cytogenetic toxicity of neem. |
| PubMed: | Inhibition of citrinin production in Penicillium citrinum cultures by neem [Azadirachta indica A. Juss (Meliaceae)]. |
| PubMed: | Response and effect of two plant crude extracts on mosquito larvae Culex pipiens. |
| PubMed: | Effect of meliaceous seed extracts on growth and survival ofSpodoptera frugiperda (J.E. Smith). |
| PubMed: | Characterization of anti-complement compounds from Azadirachta indica. |
| PubMed: | Behavioral and developmental effects of neem extracts on Clavigralla scutellaris (Hemiptera: Heteroptera: Coreidae) and its egg parasitoid, Gryon fulviventre (Hymenoptera: Scelionidae). |
| PubMed: | Analysis of neem oils by LC-MS and degradation kinetics of azadirachtin-A in a controlled environment. Characterization of degradation products by HPLC-MS-MS. |
| PubMed: | Toxicity of biorational insecticides: activity against the green peach aphid, Myzus persicae (Sulzer). |
| PubMed: | The antimicrobial effects of extracts of Azadirachta indica (Neem) and Salvadora persica (Arak) chewing sticks. |
| PubMed: | Comparative laboratory toxicity of neem pesticides to honey bees (Hymenoptera: Apidae), their mite parasites Varroa jacobsoni (Acari: Varroidae) and Acarapis woodi (Acari: Tarsonemidae), and brood pathogens Paenibacillus larvae and Ascophaera apis. |
| PubMed: | Pesticidal properties of parthenin (from Parthenium hysterophorus) and related compounds. |
| PubMed: | Toxicity of crude neem extracts (N-4) and (N-9) against late 2nd instar larvae of Musca domestica L. (PCSIR strain). |
| PubMed: | Citronella as an insect repellent in food packaging. |
| PubMed: | Field evaluation of neem and canola oil for the selective control of the honey bee (Hymenoptera: Apidae) mite parasites Varroa jacobsoni (Acari: Varroidae) and Acarapis woodi (Acari: Tarsonemidae). |
| PubMed: | Responses of beaver (Castor canadensis Kuhl) to predator chemicals. |
| PubMed: | Determination of toxicity of danitol, methoprene and neem formulation against stored grain pest, sitophilus oryzae L. |
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