Articles:
(1beta)-1-hydroxyginkgolide A
Notes:
a paf-receptor antagonist; isolated from ginkgo biloba tree; the most active ginkgolide at antagonizing paf receptors. Isol. from Ginkgo biloba (ginkgo)
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| CAS Number: | 15291-77-7 |  3D/inchi
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| FDA UNII: | DF149B9460 | |
| MDL: | MFCD05662347 | |
| XlogP3-AA: | -0.40 (est) | |
| Molecular Weight: | 424.40328000 | |
| Formula: | C20 H24 O10 | |
| BioActivity Summary: | listing | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
Physical Properties:
| Assay: | 95.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Boiling Point: | 762.00 to 763.00 °C. @ 760.00 mm Hg (est) |
| Flash Point: | 526.00 °F. TCC ( 274.30 °C. ) (est) |
| logP (o/w): | 2.070 (est) |
| Soluble in: | |
| water, 1.838e+005 mg/L @ 25 °C (est) | |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| None found |
Suppliers:
| Alfa Biotechnology |
| For experimental / research use only. |
| Ginkgolide B 98% |
| BOC Sciences |
| For experimental / research use only. |
| Ginkgolide B >98%
Odor: characteristic Use: Ginkgolide B is a PAFR antagonist with IC50 of 3.6 nM. |
| ExtraSynthese |
| For experimental / research use only. |
| Ginkgolide B (HPLC) ≥98% |
| Nacalai USA |
| For experimental / research use only. |
| Ginkgolide B |
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| Ginkgolide B ≥90% |
| Sigma-Aldrich: Sigma |
| For experimental / research use only. |
| Ginkgolide B from Ginkgo biloba leaves ≥90% (HPLC) |
Safety Information:
| Preferred SDS: View | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
| Not determined | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | natural substances and extractives | ||
| Recommendation for ginkgolide B usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for ginkgolide B flavor usage levels up to: | |||
| not for flavor use. | |||
Safety References:
| EPI System: | View |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 65243 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 3 |
| Chemidplus: | 0015291777 |
References:
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 65243 |
| Pubchem (sid): | 135022899 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| CHEMBL: | View |
| KEGG (GenomeNet): | C07602 |
| HMDB (The Human Metabolome Database): | HMDB36861 |
| FooDB: | FDB015815 |
| VCF-Online: | VCF Volatile Compounds in Food |
| ChemSpider: | View |
| Wikipedia: | View |
| EFSA Update of results on the monitoring of furan levels in food: | Read Report |
| EFSA Previous report: Results on the monitoring of furan levels in food: | Read Report |
| EFSA Report of the CONTAM Panel on provisional findings on furan in food: | Read Report |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| None Found |
Occurrence (nature, food, other): note
| ginkgo biloba Search Trop Picture |
Synonyms:
| 11-tert- | butyl-1,4b,8-trihydroxy-5-methyltetrahydro-4bh,9h-9,4a-(epoxymethano)cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-2,6,13(1h,5h)-trione |
| 8-tert- | butyl-6,12,17-trihydroxy-16-methyl-2,4,14,19-tetraoxahexacyclo[8.7.2.01,11.03,7.07,11.013,17]nonadecane-5,15,18-trione |
| 8-(tert- | butyl)-6,12,17-trihydroxy-16-methyl-2,4,14,19-tetraoxahexacyclo[8.7.2.01,11.03,7.07,11.013,17]nonadecane-5,15,18-trione |
| ginkolide B | |
| (1beta)-1- | hydroxyginkgolide A |