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Category: pharmaceuticals / chemical synthisis
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | white crystalline solid (est) |
| Assay: | 95.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Melting Point: | 205.00 °C. @ 760.00 mm Hg
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| Boiling Point: | 302.60 °C. @ 760.00 mm Hg (est)
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| Vapor Pressure: | 0.001000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 278.00 °F. TCC ( 136.80 °C. ) (est)
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| logP (o/w): | -0.240 |
| Soluble in: |
| | water, 4219 mg/L @ 25 °C (est) |
Organoleptic Properties:
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
parenteral-hamster LD10 250 mg/kg Journal of Surgical Oncology. Vol. 15, Pg. 355, 1980.
intravenous-human TDLo 3500 ug/kg BLOOD: LEUKOPENIA
GASTROINTESTINAL: NAUSEA OR VOMITING Cancer Chemotherapy Reports, Part 1. Vol. 57, Pg. 83, 1973.
intraperitoneal-mouse LD50 567 mg/kg Cancer Treatment Reports. Vol. 62, Pg. 721, 1978.
intravenous-mouse LD50 466 mg/kg BEHAVIORAL: ANTIPSYCHOTIC
BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 9, Pg. 3105, 1981.
oral-mouse LD50 2032 mg/kg BEHAVIORAL: ANTIPSYCHOTIC
BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 9, Pg. 3105, 1981.
intraperitoneal-rat LD50 350 mg/kg Archiv fuer Geschwulstforschung. Vol. 50, Pg. 306, 1980.
intravenous-rat LD50 411 mg/kg BEHAVIORAL: ANTIPSYCHOTIC
BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 9, Pg. 3105, 1981.
oral-rat LD50 2147 mg/kg BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
BEHAVIORAL: ANTIPSYCHOTIC Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 9, Pg. 3105, 1981.
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | pharmaceuticals / chemical synthisis |
| Recommendation for dacarbazine usage levels up to: | | | not for fragrance use.
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| Recommendation for dacarbazine flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
| | (5E)-5-(dimethylaminohydrazinylidene)imidazole-4-carboxamide |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 5353562 |
| Pubchem (sid): | 134985384 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | biocarbazine R | | | dacarbazinum | | 4(5)-(3,3- | dimethyl-1-triazeno)imidazole-4-carboxamide | | 5-(3,3- | dimethyl-1-triazeno)imidazole-4-carboxamide | | 4-(3,3- | dimethyl-1-triazeno)imidazole-5-carboxamide | | 4-(5)-(3,3- | dimethyl-1-triazeno)imidazole-5(4)-carboxamide | | 4-(or 5)-(3,3- | dimethyl-1-triazeno)imidazole-5(or 4)-carboxamide | | (5E)-5-( | dimethylaminohydrazinylidene)imidazole-4-carboxamide | | 5-( | dimethyltriazeno)imidazole-4-carboxamide | | 5-(3,3- | dimethyltriazeno)imidazole-4-carboxamide | | ( | dimethyltriazeno)imidazolecarboxamide | | | imidazole-4-carboxamide, 5-(3,3-dimethyl-1-triazeno)- | | | imidazole-4-carboxamide, 5-(3,3-dimethyl-1-triazenyl)- | | 1H- | imidazole-4-carboxamide, 5-(3,3-dimethyl-1-triazenyl)- |
Articles:
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