cycasin, 14901-08-7

Articles:

PubMed:	Toxic phytochemicals and their potential risks for human cancer.
PubMed:	Relative seed and fruit toxicity of the Australian cycads Macrozamia miquelii and Cycas ophiolitica: further evidence for a megafaunal seed dispersal syndrome in cycads, and its possible antiquity.
PubMed:	Effect of methanolic extract of Vernonia amygdalina (common bitter leaf) on lipid peroxidation and antioxidant enzymes in rats exposed to cycasin.
PubMed:	Animal models of brain maldevelopment induced by cycad plant genotoxins.
PubMed:	Cycads and their association with certain neurodegenerative diseases.
PubMed:	Unraveling 50-Year-Old Clues Linking Neurodegeneration and Cancer to Cycad Toxins: Are microRNAs Common Mediators?
PubMed:	Does the cycad genotoxin MAM implicated in Guam ALS-PDC induce disease-relevant changes in mouse brain that includes olfaction?
PubMed:	Is neurodegenerative disease a long-latency response to early-life genotoxin exposure?
PubMed:	Antileishmanial, antitrypanosomal, and cytotoxic screening of ethnopharmacologically selected Peruvian plants.
PubMed:	The cycad genotoxin MAM modulates brain cellular pathways involved in neurodegenerative disease and cancer in a DNA damage-linked manner.
PubMed:	Two genera of Aulacoscelinae beetles reflexively bleed azoxyglycosides found in their host cycads.
PubMed:	A survey of phytotoxic microbial and plant metabolites as potential natural products for pest management.
PubMed:	[Studies on the chemical constituents of the roots of Anemone altaica].
PubMed:	Return of the cycad hypothesis - does the amyotrophic lateral sclerosis/parkinsonism dementia complex (ALS/PDC) of Guam have new implications for global health?
PubMed:	Molecular networks perturbed in a developmental animal model of brain injury.
PubMed:	Azoxyglycoside content and beta-glycosidase activities in leaves of various cycads.
PubMed:	Acute Cycas seed poisoning in Taiwan.
PubMed:	Western Pacific ALS/PDC and flying foxes: What's next?
PubMed:	Cycads: their evolution, toxins, herbivores and insect pollinators.
PubMed:	Behavioral and neurological correlates of ALS-parkinsonism dementia complex in adult mice fed washed cycad flour.
PubMed:	Toxicology. Fruit bats linked to mystery disease.
PubMed:	Cycad neurotoxins, consumption of flying foxes, and ALS-PDC disease in Guam.
PubMed:	Effects of single injection of methylazoxymethanol at postnatal day one on cell proliferation in different brain regions of male rats.
PubMed:	SOS induction of selected naturally occurring substances in Escherichia coli (SOS chromotest).
PubMed:	Damage and repair of nerve cell DNA in toxic stress.
PubMed:	The Guam cycad toxin methylazoxymethanol damages neuronal DNA and modulates tau mRNA expression and excitotoxicity.
PubMed:	Cycad poisoning in cattle in Japan--studies on spontaneous and experimental cases.
PubMed:	Are age-related neurodegenerative diseases linked with various types of magnesium depletion?
PubMed:	Na+-dependent and phlorizin-inhibitable transport of glucose and cycasin in brain endothelial cells.
PubMed:	ApoE and CYP2D6 polymorphism with and without parkinsonism-dementia complex in the people of Chamorro, guam.
PubMed:	Neuroepidemiology of amyotrophic lateral sclerosis: clues to aetiology and pathogenesis.
PubMed:	Motor neuron disease on Guam: geographic and familial occurrence, 1956-85.
PubMed:	Potential role of environmental genotoxic agents in diabetes mellitus and neurodegenerative diseases.
PubMed:	Substrate specificity and transglucosylation catalyzed by cycad beta-glucosidase.
PubMed:	A partially purified beta-glucosidase from Bifidobacterium adolescentis converts cycasin to a mutagenic compound.
PubMed:	Cycad toxin-induced damage of rodent and human pancreatic beta-cells.
PubMed:	Genotoxic activity in vivo of the naturally occurring glucoside, cycasin, in the Drosophila wing spot test.
PubMed:	Early biochemical events in mice exposed to cycas and fed a Nigerian-like diet.
PubMed:	Transport of cycasin by the intestinal Na+/glucose cotransporter.
PubMed:	The magical and medicinal usage of Stangeria eriopus in South Africa.
PubMed:	Tumor incidence in a chemical carcinogenesis study of nonhuman primates.
PubMed:	Seeds of discovery: a new look at one environmental factor in Alzheimer's disease.
PubMed:	Guam ALS-PDC: possible causes.
PubMed:	Content of the neurotoxins cycasin (methylazoxymethanol beta-D-glucoside) and BMAA (beta-N-methylamino-L-alanine) in cycad flour prepared by Guam Chamorros.
PubMed:	Long-latency neurodegenerative disease in the western Pacific.
PubMed:	Slow toxins, biologic markers, and long-latency neurodegenerative disease in the western Pacific region.
PubMed:	Dietary protein and chronic toxicity of 1,2-dimethylhydrazine fed to mice.
PubMed:	Mutagenicity of methylazoxymethanol acetate in the presence of alcohol dehydrogenase, aldehyde dehydrogenase, and rat liver microsomes in Salmonella typhimurium His G46.
PubMed:	Intestinal microflora: metabolism of drugs and carcinogens.
PubMed:	Etiology of Alzheimer's disease: a western pacific view.
PubMed:	Acquired chemical defense in the lycaenid butterfly,Eumaeus atala.
PubMed:	Mutagenic activity of promutagens in plants: indirect evidence of their activation.
PubMed:	A poison tree.
PubMed:	Statistical analysis of a carcinogen mixture experiment. I. Liver carcinogens.
PubMed:	Hepatic and spinal lesions in goats chronically intoxicated with cycasin.
PubMed:	On the distribution of genotoxic factors in various organs of mice treated with cycasin.
PubMed:	Induction of tumors with cycasin in newborn and preweanling rats.
PubMed:	Animal model for colorectal cancer.
PubMed:	Diet and nutrition as risk factors for cancer.
PubMed:	[Experimental multiple primary malignant tumors induced by chemical carcinogen].
PubMed:	Review: putative mutagens and carcinogens in foods. V. Cycad azoxyglycosides.
PubMed:	Potentiation of large intestinal tumorigenicity of cycasin derivative by high-fat diet and Lactobacillus in germfree mice.
PubMed:	Activation of cycasin to a mutagen for Saccharomyces cerevisiae by rat intestinal flora.
PubMed:	Bacterial mutagenicity of natural materials, pyrolysis products and additives in foodstuffs and their association with genotoxic effects in mammals.
PubMed:	Cycasin and its mutagenic metabolites.
PubMed:	Genetic damage caused by methylazoxymethanol acetate, the aglycone of cycasin. Analysis of sister-chromatid exchange frequency under in vivo conditions and in cell cultures.
PubMed:	Comparison of the carcinogenicity of methylazoxymethanol-beta-D-glucosiduronic acid in conventional and germfree Sprague-Dawley rats.
PubMed:	Determination of the carcinogen methylazoxymethyl-beta-D-glucosiduronic acid in rat bile and urine.
PubMed:	Natural carcinogenic products of plant origin.
PubMed:	[Occurrence of neoplasms in the large intestine and role of intestinal bacteria].
PubMed:	Genotoxicity of cycasin in the hepatocyte primary culture/DNA repair test supplemented with beta-glucosidase.
PubMed:	Rapid hepatoma induction in rats by dipentylnitrosamine and its modification by other carcinogens.
PubMed:	Effect of phenobarbital on the development of neoplastic lesions in the liver of cycasin-treated rats.
PubMed:	[Classification, histochemistry and ultrastructure of experimental renal tumors (author's transl)].
PubMed:	Carcinogenicity and hepatotoxicity of cycasin and its aglycone methylazoxymethanol acetate in nonhuman primates.
PubMed:	Role of bacteria in human carcinogenesis.
PubMed:	Mutagenicity of the naturally occurring carcinogen cycasin and synthetic methylazoxymethanol conjugates in Salmonella typhimurium.
PubMed:	Synthesis of the glucuronic acid conjugate of methylazoxymethanol.
PubMed:	DNA fragmentation in some organs of rats and mice treated with cycasin.
PubMed:	Mutagenicity of alkaloids in the Salmonella/microsome system.
PubMed:	Contributions of gnotobiology to nutrition science.
PubMed:	Toxins and carcinogens in the environment: an observation in the tropics.
PubMed:	A practical procedure for testing DNA damage in vivo, proposed for a pre-screening of chemical carcinogens.
PubMed:	[Histology, fine structure and differentiation of experimental Wilms tumors (author's transl)].
PubMed:	Naturally occurring compounds Containing a nitrogen-nitrogen bond.
PubMed:	Cancer and the environment.
PubMed:	Effect of coffee on carcinogenicity of cycasin.
PubMed:	PHA response and methylazoxymethanol acetate.
PubMed:	Pathogenesis of methylazoxymethanol-induced lesions in the postnatal mouse cerebellum.
PubMed:	Carcinogens occurring naturally in foods.
PubMed:	Leiomyomas and leiomyosarcomas of the kidney in 4-day-old BUF rats given methylazoxymethanol acetate intraperitoneally.
PubMed:	Naturally occuring mutagens.
PubMed:	Cycasin.
PubMed:	Experimental carcinogenesis in small aquarium fishes.
PubMed:	[Microorganisms as indicators of the mutagenic activity of chemical compounds and their metabolites].
PubMed:	Intestinal tumors of rats by gastric or intestinal administration of cycad extract and cycasin.
PubMed:	Hepatic tumors of rabbits induced by cycad extract.
PubMed:	Dendritic growth in vitro.
PubMed:	[Ultrastructure of cycasin-induced adenomas of kidney (author's transl)].
PubMed:	Renal carcinogenesis.
PubMed:	The alkylation of nucleic acids of rat and mouse in vivo by the carcinogen 1,2-dimethylhydrazine.
PubMed:	Morphological and biochemical effects of 1,2-dimethylhydrazine and 1-methylhydrazine in rats and mice.
PubMed:	[Cycasin carcinogenesis. (5). Carcinogenic properties of cycasin, methylazoxymethanol and methylazoxymethyl benzoate].
PubMed:	Acute hepatic lesions induced by cycasin.
PubMed:	Induction of a retinal disorder with cycasin in newborn mice and rats.
PubMed:	Relations between postnatal days of mice and carcinogenic effect of cycasin.
PubMed:	High yield of hepatic tumors in rats by cycasin.
PubMed:	Cycasin-induced central nervous system lesions in postnatal mice.
PubMed:	Fine structure of cycasin-induced cerebellar alterations.
PubMed:	Cycasin in cycad materials used in Japan.
PubMed:	Lipid composition of the cerebellum and spinal cord in postnatal cycasin-treated Swiss albino mice: preliminary observations.
PubMed:	Carcinogenicity and neurotoxicity of cycasin with sepcial reference to species differences.
PubMed:	-Glucosidase modulation in preweanling rats and its association with tumor induction by cycasin.
PubMed:	[Natural carcinogens: target organs and species specificity in induction of cancer by single administration of cycasin].
PubMed:	[Natural carcinogens: aglycon-methylazoxymethanol in cycasin].
PubMed:	[Natural carcinogens: isolation of cycasin].
PubMed:	[Natural carcinogens: toxicity and carcinogenicity of cyasin: induction of tumors by cycasin in the seeds of Cycas revoluta].
PubMed:	[Natural carcinogens: hepatic disorders in the rat caused by cycasin, with special reference to the induction of hepatic tumors].
PubMed:	Decomposition of methylazoxymethanol, the aglycone of cycasin, in D 2 O.
PubMed:	An electron microscopic study of cycasin-induced cerebellar alterations.
PubMed:	Shift of target organs in cycasin carcinogenesis.
PubMed:	Dose related effects of cycasin induced renal and hepatic tumors.
PubMed:	Carcinogenic effects of cycasin in Syrian golden hamsters and the transplantability of induced tumors.
PubMed:	High incidence of pulmonary tumors in dd mice by a single injection of cycasin.
PubMed:	[Carcinogenesis by cycasin, with special reference to the target organs].
PubMed:	Tumor induction in C57BL-6 mice by a single administration of cycasin.
PubMed:	Induction of a cerebellar disorder with cycasin in newborn mice and hamsters.
PubMed:	Cycling of cycasin from newborn rats to their mother and back to the newborn.
PubMed:	Cycasin: detection of associated mutagenic activity in vivo.
PubMed:	[Cycasin-induced renal tumors in the Wistar rat with special consideration of the adenoma].
PubMed:	Toxicology of cycasin.
PubMed:	Toxicology of cycasin.
PubMed:	Effect of cycasin on protein synthesis.
PubMed:	Induction of mammary cancer in rats with cycasin: a preliminary report.
PubMed:	Tumor induction in Fischer and Osborne-Mendel rats by a single administration of cycasin.
PubMed:	Transplantability of cycasin-induced tumors in rats, with emphasis on nephroblastomas.
PubMed:	Evidence for transplacental passage of the natural carcinogen cycasin and its aglycone.
PubMed:	Induction of a neurological disorder by cycasin in mice.
PubMed:	Similarities between the biochemical actions of cycasin and dimethylnitrosamine.
PubMed:	Tumor induction in germfree rats with methylazoxymethanol (MAM) and synthetic MAM acetate.
PubMed:	Mutation in Drosophila by methylazoxymethanol, the aglycone of cycasin.
PubMed:	Cycasin synthesis in Seirarctia echo (Lepidoptera) larvae fed methylazoxymethanol.
PubMed:	Role of intestinal microorganisms in determining cycasin toxicity.
PubMed:	[Histological-histochemical studies on the "interstitial cycasin tumor" of rat kidneys].
PubMed:	Mutagenicity of cycasin aglycone (methylazoxymethanol), a naturally occurring carcinogen.
PubMed:	Effect of boiling and storing on cycasin content of Cycas circinalis L.
PubMed:	Studies on methylazoxymethanol, the aglycone of cycasin: methylation of nucleic acids in vitro.
PubMed:	Cycasin excretion in conventional and germfree rats.
PubMed:	Naturally occurring toxicants in foods.
PubMed:	The induction of intestinal neoplasms in rats with the glycoside cycasin and its aglycone.
PubMed:	CYCASIN: RADIOMIMETIC EFFECT.
PubMed:	Cycasin content of Cycas circinalis.
PubMed:	STUDIES ON METHYLAZOXYMETHANOL, THE AGLYCONE OF CYCASIN. ISOLATION, BIOLOGICAL, AND CHEMICAL PROPERTIES.
PubMed:	STUDIES ON METHYLAZOXYMETHANOL, THE AGLYCONE OF CYCASIN: A SYNTHESIS OF METHYLAZOXYMETHYL ACETATE.
PubMed:	RESPONSE OF LIVER NUCLEIC ACIDS AND LIPIDS IN RATS FED CYCAS CIRCINALIS L. ENDOSPERM OR CYCASIN.
PubMed:	EFFECT OF INGESTED CYCASIN ON RAT BLOOD PLASMA CHOLINESTERASE.
PubMed:	CARCINOGENIC EFFECTS OF CYCAD MEAL AND CYCASIN, METHYLAZOXYMETHANOL GLYCOSIDE, IN RATS AND EFFECTS OF CYCASIN IN GERMFREE RATS.
PubMed:	EFFECTS OF CYCAD MEAL AND CYCASIN ON HISTOCHEMICALLY DEMONSTRABLE LIVER PHOSPHATASES AND NON SPECIFIC ESTERASES.
PubMed:	RATES AND KINETICS OF CATALASE SYNTHESIS AND DESTRUCTION IN RATS FED CYCAD AND CYCASIN IN VIVO.
PubMed:	EFFECT OF CYCAD AND CYCASIN FEEDING ON LIVER RNA, DNA, SUCCINIC OXIDASE, AND LIPIDS IN THE RAT.
PubMed:	EFFECTS OF CYCASIN AND CYCAD MEAL.
PubMed:	METHYLAZOXYMETHANOL, THE AGLYCONE OF CYCASIN.