hirudo medicinalis extract
extract obtained from leeches
 
Notes:
None found
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Name: hirudo medicinalis extract
CAS Number: 90045-73-1 
ECHA EC Number: 289-937-6
Category: cosmetic ingredient for skin conditioning
 
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Physical Properties:
Food Chemicals Codex Listed: No
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: skin conditioning
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Suppliers:
 None found
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: cosmetic ingredient for skin conditioning
Recommendation for hirudo medicinalis extract usage levels up to:
 not for fragrance use.
 
Recommendation for hirudo medicinalis extract flavor usage levels up to:
 not for flavor use.
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Safety References:
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
 hirudo medicinalis extract
Chemidplus: 0090045731
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References:
 hirudo medicinalis extract
Pubchem (sid): 135330445
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Other Information:
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
 biological additives 
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Occurrence (nature, food, other): note
 hirudo medicinalis
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Synonyms:
 extract obtained from leeches
 hirudinea extract
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Articles:
PubMed: Development and validation of a stability-indicating method for determination of free sterols in the Asian medicinal leech Hirudo manillensis.
PubMed: [Determination of biological activity of extract from hirudo by N-benzoyl-L-arginine ethyl ester].
PubMed: Phylogenetic conservation of the cell-type-specific Lan3-2 glycoepitope in Caenorhabditis elegans.
PubMed: [Medicinal leeches].
PubMed: Exploring the "intensity fading" phenomenon in the study of noncovalent interactions by MALDI-TOF mass spectrometry.
PubMed: Detection of noncovalent complexes in biological samples by intensity fading and high-mass detection MALDI-TOF mass spectrometry.
PubMed: Functional screening of serine protease inhibitors in the medical leech Hirudo medicinalis monitored by intensity fading MALDI-TOF MS.
PubMed: The neurite-stimulating influence of components of medicinal leech salivary gland secretions in organotypic culture of spinal ganglia.
PubMed: [Contact dermatitis with Hirudo medicinalis].
PubMed: Hirudin as alternative anticoagulant--a historical review.
PubMed: Efficacy and safety of topical hirudin (Hirudex): a double-blind, placebo-controlled study.
PubMed: Evidence for an endocannabinoid system in the central nervous system of the leech Hirudo medicinalis.
PubMed: [Antithrombotic effect of piavit--a substance from the medicinal leech (Hirudo medicinalis), containing prostanoid and destabilase fractions].
PubMed: Arterial antithrombotic effect of piyavit, the novel pharmacological preparation from the medicinal leech, and of its components, prostanoids and enzyme destabilase.
PubMed: Defined neuronal arborizations by guided outgrowth of leech neurons in culture.
PubMed: Identification of a 70 kD protein with sequence homology to squid neurofilament protein in glial cells of the leech CNS.
PubMed: Protease inhibitors in the alimentary tract of the medicinal leech Hirudo medicinalis: in vivo and in vitro studies.
PubMed: Interaction of hementin with fibrinogen and fibrin.
PubMed: [The medicinal leech Hirudo medicinalis: clinical use of the animal and therapeutic prospects of hirudin].
PubMed: Effect of extract of Hirudo Medicinalis L. against adherence of calcium oxalate crystals to acid-injured bladder mucosa.
PubMed: Rapid purification and revised amino-terminal sequence of hirudin: a specific thrombin inhibitor of the bloodsucking leech.
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