Articles:
| None found yet. Try the PubMed Search. |
semuloparin
Notes:
a highly acidic mucopolysaccharide formed of equal parts of sulfated d-glucosamine and d-glucuronic acid with sulfaminic bridges. the molecular weight ranges from six to twenty thousand. heparin occurs in and is obtained from liver, lung, mast cells, etc., of vertebrates. its function is unknown, but it is used to prevent blood clotting in vivo and vitro, in the form of many different salts. A highly acidic mucopolysaccharide formed of equal parts of sulfated D-glucosamine and D-glucuronic acid with sulfaminic bridges. The molecular weight ranges from six to twenty thousand. Heparin occurs in and is obtained from liver, lung, mast cells, etc., of vertebrates. Its function is unknown, but it is used to prevent blood clotting in vivo and vitro, in the form of many different salts. [HMDB]
-
BOC Sciences Best of Chemicals Supplier Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services. BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies. Email: Marketing US Email: Marketing Email: Sales US Email: Sales Voice: 1-631-485-4226 Fax: 1-631-614-7828 US Voice: 1-631-485-4226 US Fax: 1-631-614-7828 Europe 44-203-286-1088 Facebook Twitter Linkedin Blog Get the App! Product(s): 9005-49-6 Heparin
-
| CAS Number: | 9005-49-6 | |
| Other(deleted CASRN): | 104521-37-1 | |
| ECHA EC Number: | 232-681-7 | |
| FDA UNII: | 7UQ7X4Y489 | |
Category: cosmetic ingredient for skin conditioning
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
Physical Properties:
| Assay: | 95.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| CosIng: | cosmetic data |
| Cosmetic Uses: |
skin conditioning |
Suppliers:
| BOC Sciences |
| For experimental / research use only. |
| Heparin |
| George Uhe Company |
| Dermatan Sulphate |
| Pangaea Sciences |
| Heparin |
| Sigma-Aldrich |
| For experimental / research use only. |
| Heparin for physico-chemical analysis European Pharmacopoeia (EP) Reference Standard |
Safety Information:
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
|
intravenous-man TDLo 3536 units/kg/ Southern Medical Journal. Vol. 80, Pg. 1450, 1987. intraperitoneal-mouse LD50 1900 mg/kg BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 60, Pg. 507, 1964. intravenous-mouse LD50 500 mg/kg BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Arzneimittel-Forschung. Drug Research. Vol. 36, Pg. 1366, 1986. oral-rat LD50 1950 mg/kg German Offenlegungsschrift Patent Document. Vol. #2636091 intraperitoneal-rat LDLo 420 mg/kg Toxicology and Applied Pharmacology. Vol. 1, Pg. 156, 1959. | |
| Dermal Toxicity: | |
|
subcutaneous-man TDLo 1857 units/kg/ CARDIAC: OTHER CHANGES Southern Medical Journal. Vol. 80, Pg. 1450, 1987. subcutaneous-mouse LD50 500 mg/kg BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: MUSCLE WEAKNESS Arzneimittel-Forschung. Drug Research. Vol. 36, Pg. 1366, 1986. | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | cosmetic ingredient for skin conditioning | ||
| Recommendation for heparin usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for heparin flavor usage levels up to: | |||
| not for flavor use. | |||
Safety References:
| ClinicalTrials.gov: | search |
| Daily Med: | search |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA Substance Registry Services (TSCA): | 9005-49-6 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 2 |
| Chemidplus: | 0009005496 |
References:
| Pubchem (sid): | 135346864 |
Other Information:
| KEGG (GenomeNet): | C00374 |
| HMDB (The Human Metabolome Database): | HMDB01394 |
| FooDB: | FDB022599 |
| VCF-Online: | VCF Volatile Compounds in Food |
| Wikipedia: | View |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| biological additives |
Occurrence (nature, food, other): note
| found in nature |
Synonyms:
| adomiparin | |
| bemiparin | |
| certoparin | |
| dermatan sulfate | |
| dermatan sulphate | |
| parnaparin | |
| reviparin | |
| sandoparin | |
| semuloparin |