fibronectin
 
Notes:
None found
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CAS Number: 86088-83-7 
ECHA EC Number: 289-149-2
MDL: MFCD00131062
Category: cosmetic agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: skin conditioning
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Suppliers:
EMD Millipore
For experimental / research use only.
Fibronectin, Human Plasma
Sigma-Aldrich: Sigma
For experimental / research use only.
Fibronectin from bovine plasma powder, BioReagent, suitable for cell culture
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Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: cosmetic agents
 
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Safety References:
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 3
Chemidplus: 0086088837
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References:
Pubchem (sid): 135338738
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Other Information:
HMDB (The Human Metabolome Database): Search
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
 biological additives 
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
 fibronectins
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Articles:
PubMed: Sodium butyrate, a HDAC inhibitor ameliorates eNOS, iNOS and TGF-β1-induced fibrogenesis, apoptosis and DNA damage in the kidney of juvenile diabetic rats.
PubMed: Infrared LED light therapy influences the expression of fibronectin and tenascin in skin wounds of malnourished rats-A preliminary study.
PubMed: PEG-PLA nanoparticles modified with APTEDB peptide for enhanced anti-angiogenic and anti-glioma therapy.
PubMed: Specific capture and detection of Staphylococcus aureus with high-affinity modified aptamers to cell surface components.
PubMed: Leonurus cardiaca L. herb--a derived extract and an ursolic acid as the factors affecting the adhesion capacity of Staphylococcus aureus in the context of infective endocarditis.
PubMed: Metyrapone Alleviates Deleterious Effects of Maternal Food Restriction on Lung Development and Growth of Rat Offspring.
PubMed: Preclinical evaluation of IL2-based immunocytokines supports their use in combination with dacarbazine, paclitaxel and TNF-based immunotherapy.
PubMed: Virgin olive oil phenolics extract inhibit invasion of HT115 human colon cancer cells in vitro and in vivo.
PubMed: Whole-genome based validation of the adaptive properties of Indian origin probiotic Lactobacillus helveticus MTCC 5463.
PubMed: Antitumor activity of the dietary diterpene carnosol against a panel of human cancer cell lines.
PubMed: Ruscogenin ameliorates diabetic nephropathy by its anti-inflammatory and anti-fibrotic effects in streptozotocin-induced diabetic rat.
PubMed: Optimal conditions of LDR to protect the kidney from diabetes: exposure to 12.5 mGy X-rays for 8 weeks efficiently protects the kidney from diabetes.
PubMed: The effects of diosgenin in the regulation of renal proximal tubular fibrosis.
PubMed: Potential Urinary Protein Biomarker Candidates for the Accurate Detection of Prostate Cancer among Benign Prostatic Hyperplasia Patients.
PubMed: Feeding of banana flower and pseudostem to diabetic rats results in modulation of renal GLUTs, TGFβ, PKC and extracellular matrix components.
PubMed: Antiadhesive properties of Abelmoschus esculentus (Okra) immature fruit extract against Helicobacter pylori adhesion.
PubMed: Grape seed extract attenuates arsenic-induced nephrotoxicity in rats.
PubMed: A celiac cellular phenotype, with altered LPP sub-cellular distribution, is inducible in controls by the toxic gliadin peptide P31-43.
PubMed: Rubus idaeus L. reverses epithelial-to-mesenchymal transition and suppresses cell invasion and protease activities by targeting ERK1/2 and FAK pathways in human lung cancer cells.
PubMed: Renoprotective effect of Coccinia indica fruits and leaves in experimentally induced diabetic rats.
PubMed: An Aqueous-Ethanol Extract of Liriope spicata var. prolifera Ameliorates Diabetic Nephropathy through Suppression of Renal Inflammation.
PubMed: Identification of compounds from the water soluble extract of Cinnamomum cassia barks and their inhibitory effects against high-glucose-induced mesangial cells.
PubMed: Polyphenols of Hibiscus sabdariffa improved diabetic nephropathy via attenuating renal epithelial mesenchymal transition.
PubMed: Supplementation of cyanidin-3-O-β-glucoside promotes endothelial repair and prevents enhanced atherogenesis in diabetic apolipoprotein E-deficient mice.
PubMed: A recombinant matriptase causes an increase in caspase-3 activity in a small-intestinal epithelial IEC-6 line cultured on fibronectin-coated plates.
PubMed: Effect of pH, salt and chemical rinses on bacterial attachment to extracellular matrix proteins.
PubMed: In vitro colonization of the muscle extracellular matrix components by Escherichia coli O157:H7: the influence of growth medium, temperature and pH on initial adhesion and induction of biofilm formation by collagens I and III.
PubMed: Identification of Salmonella enterica genes with a role in persistence on lettuce leaves during cold storage by recombinase-based in vivo expression technology.
PubMed: Iron chelator alleviates tubulointerstitial fibrosis in diabetic nephropathy rats by inhibiting the expression of tenascinC and other correlation factors.
PubMed: Riboflavin at high doses enhances lung cancer cell proliferation, invasion, and migration.
PubMed: In vitro and in vivo characterization of DNA delivery using recombinant Lactococcus lactis expressing a mutated form of L. monocytogenes Internalin A.
PubMed: Association between the plasma proteome and plasma α-tocopherol concentrations in humans.
PubMed: Curcumin alleviates oxidative stress, inflammation, and renal fibrosis in remnant kidney through the Nrf2-keap1 pathway.
PubMed: Knockout of Na-glucose transporter SGLT2 attenuates hyperglycemia and glomerular hyperfiltration but not kidney growth or injury in diabetes mellitus.
PubMed: Modulation of feeding by chronic rAAV expression of a relaxin-3 peptide agonist in rat hypothalamus.
PubMed: Isolation of potential probiotic Lactobacillus rhamnosus strains from traditional fermented mare milk produced in Sumbawa Island of Indonesia.
PubMed: Zinc inhibits magnesium-dependent migration of human breast cancer MDA-MB-231 cells on fibronectin.
PubMed: Melamine induces human renal proximal tubular cell injury via transforming growth factor-β and oxidative stress.
PubMed: Organochlorine pesticides induce epithelial to mesenchymal transition of human primary cultured hepatocytes.
PubMed: GEF-H1 over-expression in hepatocellular carcinoma promotes cell motility via activation of RhoA signalling.
PubMed: Effects of yeast cell wall-derived mannan-oligosaccharides on jejunal gene expression in young broiler chickens.
PubMed: Naringenin inhibits extracellular matrix production via extracellular signal-regulated kinase pathways in nasal polyp-derived fibroblasts.
PubMed: Bacterial attachment to immobilized extracellular matrix proteins in vitro.
PubMed: Renal histopathology of a baboon model with type 2 diabetes.
PubMed: Rapid paracellular transmigration of Campylobacter jejuni across polarized epithelial cells without affecting TER: role of proteolytic-active HtrA cleaving E-cadherin but not fibronectin.
PubMed: Eosinophilic esophagitis: epithelial mesenchymal transition contributes to esophageal remodeling and reverses with treatment.
PubMed: Erythrocytes express chondroitin sulphate/dermatan sulphate, which undergoes quantitative changes during diabetes and mediate erythrocyte adhesion to extracellular matrix components.
PubMed: Angelica acutiloba root alleviates advanced glycation end-product-mediated renal injury in streptozotocin-diabetic rats.
PubMed: Protective effect of yacon leaves decoction against early nephropathy in experimental diabetic rats.
PubMed: Anti-inflammatory and antifibrotic effects of naringenin in diabetic mice.
PubMed: Curcumin attenuates diabetic nephropathy by inhibiting PKC-α and PKC-β1 activity in streptozotocin-induced type I diabetic rats.
PubMed: Curcumin suppresses Streptococcus mutans adherence to human tooth surfaces and extracellular matrix proteins.
PubMed: Tissue engineering a fetal membrane.
PubMed: Selection of non-competitive leptin antagonists using a random nanobody-based approach.
PubMed: Virulence factors and genetic characteristics of methicillin-resistant and -susceptible Staphylococcus aureus isolates in Myanmar.
PubMed: The genome sequence of the lactic acid bacterium, Carnobacterium maltaromaticum ATCC 35586 encodes potential virulence factors.
PubMed: Copper ability to induce premature senescence in human fibroblasts.
PubMed: Antiglycative effects of protocatechuic acid in the kidneys of diabetic mice.
PubMed: Diabetes results in structural alteration of chondroitin sulfate/dermatan sulfate in the rat kidney: effects on the binding to extracellular matrix components.
PubMed: Binding to extracellular matrix proteins and formation of biogenic amines by food-associated coagulase-negative staphylococci.
PubMed: DNA microarray based detection of genes involved in safety and technologically relevant properties of food associated coagulase-negative staphylococci.
PubMed: Major host factors involved in epithelial cell invasion of Campylobacter jejuni: role of fibronectin, integrin beta1, FAK, Tiam-1, and DOCK180 in activating Rho GTPase Rac1.
PubMed: Luteolin ameliorates experimental lung fibrosis both in vivo and in vitro: implications for therapy of lung fibrosis.
PubMed: Parenteral and enteral feeding in preterm piglets differently affects extracellular matrix proteins, enterocyte proliferation and apoptosis in the small intestine.
PubMed: A recombinant catalytic domain of matriptase induces detachment and apoptosis of small-intestinal epithelial IEC-6 cells cultured on laminin-coated surface.
PubMed: Andrographolide and 14-deoxy-11,12-didehydroandrographolide from Andrographis paniculata attenuate high glucose-induced fibrosis and apoptosis in murine renal mesangeal cell lines.
PubMed: Relationships between pregnancy outcomes, biochemical markers and pre-pregnancy body mass index.
PubMed: Binding of Host Factors Influences Internalization and Intracellular Trafficking of Streptococcus uberis in Bovine Mammary Epithelial Cells.
PubMed: Functional roles of aggregation-promoting-like factor in stress tolerance and adherence of Lactobacillus acidophilus NCFM.
PubMed: Peptides from Pisum sativum L. enzymatic protein digest with anti-adhesive activity against Helicobacter pylori: structure-activity and inhibitory activity against BabA, SabA, HpaA and a fibronectin-binding adhesin.
PubMed: The activities of MMP-9 and total gelatinase respond differently to substrate coating and cyclic mechanical stretching in fibroblasts and myoblasts.
PubMed: Interaction between myostatin and extracellular matrix components.
PubMed: Functional and probiotic attributes of an indigenous isolate of Lactobacillus plantarum.
PubMed: Campylobacter jejuni FlpA binds fibronectin and is required for maximal host cell adherence.
PubMed: Chemical characterization, antiproliferative and antiadhesive properties of polysaccharides extracted from Pleurotus pulmonarius mycelium and fruiting bodies.
PubMed: Staphylococcus aureus: the toxic presence of a pathogen extraordinaire.
PubMed: Supplemental calcium attenuates the colitis-related increase in diarrhea, intestinal permeability, and extracellular matrix breakdown in HLA-B27 transgenic rats.
PubMed: Cellular receptors of extracellular matrix molecules.
PubMed: Characterization of two putative fibronectin-binding proteins of Clostridium perfringens.
PubMed: Inhibitory effects of gamma-tocotrienol on invasion and metastasis of human gastric adenocarcinoma SGC-7901 cells.
PubMed: Effect of ochratoxin A on cell survival and collagen homeostasis in human mesangial cells in primary culture.
PubMed: Adhesion properties of Lactobacillus casei strains to resected intestinal fragments and components of the extracellular matrix.
PubMed: The type 4 pili of enterohemorrhagic Escherichia coli O157:H7 are multipurpose structures with pathogenic attributes.
PubMed: A lymphocyte serine protease granzyme A causes detachment of a small-intestinal epithelial cell line (IEC-6).
PubMed: [Inhibitory effects of BIO-1211 on bronchoconstriction and neutrophil adhesion in rats].
PubMed: Endostar suppresses invasion through downregulating the expression of matrix metalloproteinase-2/9 in MDA-MB-435 human breast cancer cells.
PubMed: Effect of platelet-rich plasma on cell adhesion, cell migration, and myofibroblastic differentiation in human gingival fibroblasts.
PubMed: Three-dimensional observation of connective tissue of bovine masseter muscle under concentrate- and roughage-fed conditions by using immunohistochemical/confocal laser-scanning microscopic methods.
PubMed: Functional and structural properties of CbpA, a collagen-binding protein from Arcanobacterium pyogenes.
PubMed: Cathepsin L activity controls adipogenesis and glucose tolerance.
PubMed: Protective effect of Hachimi-jio-gan against the development of pancreatic fibrosis and oxidative damage in Otsuka Long-Evans Tokushima Fatty rats.
PubMed: Mechanical stimulation increases proliferation, differentiation and protein expression in culture: stimulation effects are substrate dependent.
PubMed: Expression patterns and role of the CadF protein in Campylobacter jejuni and Campylobacter coli.
PubMed: Isolation of surface (S) layer protein carrying Lactobacillus species from porcine intestine and faeces and characterization of their adhesion properties to different host tissues.
PubMed: Role of the small Rho GTPases Rac1 and Cdc42 in host cell invasion of Campylobacter jejuni.
PubMed: Long-term effects of ochratoxin A on fibrosis and cell death in human proximal tubule or fibroblast cells in primary culture.
PubMed: Inflammatory gene expression patterns revealed by DNA microarray analysis in TNF-alpha-treated SGBS human adipocytes.
PubMed: Leptin and renal fibrosis.
PubMed: Inhibition of tumor invasion and metastasis by aqueous extract of the radix of Platycodon grandiflorum.
PubMed: Functional analysis of putative adhesion factors in Lactobacillus acidophilus NCFM.
PubMed: Curcuma longa L. constituents inhibit sortase A and Staphylococcus aureus cell adhesion to fibronectin.
PubMed: Remodeling of actin cytoskeleton in lupeol-induced B16 2F2 cell differentiation.
PubMed: Micromechanical cantilever array sensors for selective fungal immobilization and fast growth detection.
PubMed: Expression pattern of matrix metalloproteinases in alcohol- and thermally oxidized sunflower oil-induced toxicity: protective role of an aminothiazole derivative.
PubMed: Effects of intrauterine food restriction and long-term dietary supplementation with L-arginine on age-related changes in renal function and structure of rats.
PubMed: Complete genome sequence of the probiotic lactic acid bacterium Lactobacillus acidophilus NCFM.
PubMed: Crystal structure and binding properties of the Serratia marcescens chitin-binding protein CBP21.
PubMed: Binding interaction studies of the immobilized Salmonella typhimurium with extracellular matrix and muscle proteins, and polysaccharides.
PubMed: Effects of c9,t11-conjugated linoleic acid on adhesion of human gastric carcinoma cell line SGC-7901.
PubMed: Possible role of amyloid beta-(1-40)-BSA conjugates in transdifferentiation of lens epithelial cells.
PubMed: The ShdA adhesin binds to the cationic cradle of the fibronectin 13FnIII repeat module: evidence for molecular mimicry of heparin binding.
PubMed: Effect of food on pharmacokinetics of an inhaled drug: a case study with a VLA-4 antagonist, HMR1031.
PubMed: Inhibitory effects of c9, t11-conjugated linoleic acid on invasion of human gastric carcinoma cell line SGC-7901.
PubMed: Binding of extracellular matrix molecules by probiotic bacteria.
PubMed: The Arcanobacterium pyogenes collagen-binding protein, CbpA, promotes adhesion to host cells.
PubMed: Retinoids as a potential treatment for experimental puromycin-induced nephrosis.
PubMed: [Renal effects of low doses of mercury].
PubMed: T lymphocytes in food allergy: overview of an intricate network of circulating and organ-resident cells.
PubMed: Bovine somatotropin administration to dairy goats in late lactation: effects on mammary gland function, composition and morphology.
PubMed: Basement membrane and connective tissue proteins in intestinal mucosa of patients with coeliac disease.
PubMed: A role for membrane-type serine protease (MT-SP1) in intestinal epithelial turnover.
PubMed: A fibronectin-binding protein from rice bran with cell adhesion activity for animal tumor cells.
PubMed: Reversal of cardiac and renal fibrosis by pirfenidone and spironolactone in streptozotocin-diabetic rats.
PubMed: Radiolabeled peptides in the detection of deep venous thrombosis.
PubMed: Identification of differentially expressed genes following treatment of monkey kidney cells with the mycotoxin fumonisin B(1).
PubMed: Intrauterine food restriction as a determinant of nephrosclerosis.
PubMed: Reduction in left ventricular messenger RNA for transforming growth factor beta(1) attenuates left ventricular fibrosis and improves survival without lowering blood pressure in the hypertensive TGR(mRen2)27 Rat.
PubMed: Cloning, sequencing and characterisation of a Listeria monocytogenes gene encoding a fibronectin-binding protein.
PubMed: Nutritional follow-up of critically ill infants receiving short term parenteral nutrition.
PubMed: Listeria monocytogenes possesses adhesins for fibronectin.
PubMed: The absence of cecal colonization of chicks by a mutant of Campylobacter jejuni not expressing bacterial fibronectin-binding protein.
PubMed: Dietary glycotoxins: inhibition of reactive products by aminoguanidine facilitates renal clearance and reduces tissue sequestration.
PubMed: Reversal of cardiac fibrosis in deoxycorticosterone acetate-salt hypertensive rats by inhibition of the renin-angiotensin system.
PubMed: The contribution of nitric oxide to renal vascular wall thickening in rats with L-NAME-induced hypertension.
PubMed: Co-ligation of alpha4beta1 integrin and TCR rescues human thymocytes from steroid-induced apoptosis.
PubMed: Influence of food consistency and dental extractions on the rat mandibular condyle: a morphological, histological and immunohistochemical study.
PubMed: Interaction between the carboxyl-terminal heparin-binding domain of fibronectin and (-)-epigallocatechin gallate.
PubMed: Anorexigen (TNF-alpha, cholecystokinin) and orexigen (neuropeptide Y) plasma levels in peritoneal dialysis (PD) patients: their relationship with nutritional parameters.
PubMed: Properties of human milk and their relationship with maternal nutrition.
PubMed: Orally absorbed reactive glycation products (glycotoxins): an environmental risk factor in diabetic nephropathy.
PubMed: Effects of small-peptide and whole-protein enteral feedings on serum proteins and diarrhea in critically ill patients: a randomized trial.
PubMed: In vitro and in vivo effects of selenium and selenium with vitamin E on platelet functions in diabetic rats relationship to platelet sorbitol and fatty acid distribution.
PubMed: Evidence for the interaction between (-)-epigallocatechin gallate and human plasma proteins fibronectin, fibrinogen, and histidine-rich glycoprotein.
PubMed: V+ fibronectin mRNA is increased in the brains of aged rats: effect of food restriction.
PubMed: [The effect of fibronectin on generation of superoxide anion by neutrophils during food poisoning and experimental salmonella endotoxemia].
PubMed: Regulation of leukocyte adhesion and signaling in inflammation and disease.
PubMed: [Genetic diagnosis of colorectal cancer].
PubMed: Cardiac levels of fibronectin, laminin, isomyosins, and cytochrome c oxidase of weanling rats are more vulnerable to copper deficiency than those of postweanling rats.
PubMed: Fibronectin mRNA (FN-V95+) is increased in the liver of old Sprague-Dawley rats: effect of food restriction.
PubMed: Dietary omega-3 lipids delay the onset and progression of autoimmune lupus nephritis by inhibiting transforming growth factor beta mRNA and protein expression.
PubMed: Hormonal and extracellular matrix regulation of plasminogen activator in a bovine mammary epithelial cell line.
PubMed: Copper deficiency alters isomyosin types and levels of laminin, fibronectin and cytochrome c oxidase subunits from rat hearts.
PubMed: Isolation of a novel collagen-binding protein from the mushroom, Hypsizigus marmoreus, which inhibits the Lewis lung carcinoma cell adhesion to type IV collagen.
PubMed: Pathogenic potential of lactobacilli.
PubMed: Effect of abrasion of teat orifice epithelium on development of bovine staphylococcal mastitis.
PubMed: Increased expression of alpha 4 beta 1 and alpha 5 beta 1 integrins on HTLV-I-infected lymphocytes.
PubMed: Immunochemical localization of integrin subunits in the human placenta.
PubMed: Perinatal food restriction in rats reduces the content but not concentration of liver extracellular matrix proteins.
PubMed: Cholesterol, macrophages, and gene expression of TGF-beta 1 and fibronectin during nephrosis.
PubMed: Electro-magnetic fields in the home environment (color TV, computer monitor, microwave oven, cellular phone, etc) as potential contributing factors for the induction of oncogen C-fos Ab1, oncogen C-fos Ab2, integrin alpha 5 beta 1 and development of cancer, as well as effects of microwave on amino acid composition of food and living human brain.
PubMed: Alterations in bronchoalveolar lavage fluid but not in lung function and bronchial responsiveness in swine confinement workers.
PubMed: Myosin light chain kinase inhibitors ML-7 and ML-9 inhibit mouse lung carcinoma cell attachment to the fibronectin substratum.
PubMed: The minimal essential sequence for a major cell type-specific adhesion site (CS1) within the alternatively spliced type III connecting segment domain of fibronectin is leucine-aspartic acid-valine.
PubMed: Characterization of lipoprotein secreted by cultured eel hepatocytes and its comparison with serum lipoproteins.
PubMed: Establishment of a macrophagelike cell line derived from U-937, human histiocytic lymphoma, grown serum-free.
PubMed: A novel human hepatoblastoma cell line (HuH-6KK) with rapid growth in serum-free medium without extracellular matrix.
PubMed: [In vitro use of a model for studying the effects of tumor promoters in food].
PubMed: [The plasma fibronectin level in food poisoning].
PubMed: Plasma fibronectin concentrations in breast fed and formula fed neonates.
PubMed: [Dynamics of the plasma fibronectin level in patients with food poisoning].
PubMed: Comparison of serum fibronectin, prealbumin, and albumin concentrations during nutritional repletion in protein-calorie malnourished infants.
PubMed: Changes in nutritional assessment variables caused by total parenteral nutrition in anorexia nervosa.
PubMed: Immediate postoperative feeding in urological surgery.
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