Articles:
Notes:
formed from pig pepsinogen by cleavage of one peptide bond. the enzyme is a single polypeptide chain and is inhibited by methyl 2-diaazoacetamidohexanoate. it cleaves peptides preferentially at the carbonyl linkages of phenylalanine or leucine and acts as the principal digestive enzyme of gastric juice. Used in the preparation of fish meal and other protein hydrolysates and in the manuf. of cheese as a milk-clotting agent
Pepsin is an enzyme that is released by the chief cells in the stomach and that degrades food proteins into peptides. Pepsin was discovered in 1836 by Theodor Schwann who also coined this enzyme's name from the Greek word pepsis, meaning digestion (peptein: to digest). It was the first animal enzyme to be discovered, and, in 1929, it became one of the first enzymes to be crystallized, by John H. Northrop. Pepsin is a digestive protease.
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| CAS Number: | 9001-75-6 | |
| ECHA EC Number: | 232-629-3 | |
| FDA UNII: | GID333S43J | |
| Formula: | unspecified | |
Category: enzyme preparations and microorganisms
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Perfumer and Flavorist: | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
| JECFA Food Additive: | Pepsin from Hog Stomach |
| FDA Mainterm (SATF): | 9001-75-6 ; PEPSIN |
| FDA Regulation: | |
| FDA PART 137 -- CEREAL FLOURS AND RELATED PRODUCTS Subpart B--Requirements for Specific Standardized Cereal Flours and Related Products Sec. 137.305 Enriched farina. FDA PART 184 -- DIRECT FOOD SUBSTANCES AFFIRMED AS GENERALLY RECOGNIZED AS SAFE Subpart B--Listing of Specific Substances Affirmed as GRAS Sec. 184.1595 Pepsin. | |
Physical Properties:
| Appearance: | pale tan, amber or brown powder, past or liquid (est) |
| Food Chemicals Codex Listed: | No |
| Soluble in: | |
| water | |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| CosIng: | cosmetic data |
| Cosmetic Uses: |
hair conditioning skin conditioning |
Suppliers:
Safety Information:
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
| Not determined | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | enzyme preparations and microorganisms | ||
| Recommendation for pepsin A usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for pepsin A flavor usage levels up to: | |||
| not for flavor use. | |||
Safety References:
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA Substance Registry Services (TSCA): | 9001-75-6 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| National Institute of Allergy and Infectious Diseases: | Data |
| Chemidplus: | 0009001756 |
References:
| Pubchem (sid): | 135274930 |
Other Information:
| FDA Substances Added to Food (formerly EAFUS): | View |
| HMDB (The Human Metabolome Database): | Search |
| FooDB: | FDB018680 |
| FDA Listing of Food Additive Status: | View |
| VCF-Online: | VCF Volatile Compounds in Food |
| Wikipedia: | View |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| biological additives |
Occurrence (nature, food, other): note
| pepsin A Search PMC Picture | |
| pepsin fortior Search PMC Picture |
Synonyms:
| pepsin fortior | |
| pepsin, bovine |