Articles:
| PubMed: | Isolation of an anti-angiogenic substance from Agaricus blazei Murill: its antitumor and antimetastatic actions. |
| PubMed: | Brain penetration of orally administered sodium pyroglutamate. |
proline, 5-oxo-, monosodium salt, L- (8CI)
Notes:
a cyclized derivative of l-glutamic acid. elevated blood levels may be associated with problems of glutamine or glutathione metabolism.
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BOC Sciences Best of Chemicals Supplier Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services. BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies. Email: Marketing US Email: Marketing Email: Sales US Email: Sales Voice: 1-631-485-4226 Fax: 1-631-614-7828 US Voice: 1-631-485-4226 US Fax: 1-631-614-7828 Europe 44-203-286-1088 Facebook Twitter Linkedin Blog Get the App! Product(s): 28874-51-3 sodium (2S)-5-oxopyrrolidine-2-carboxylate 98%
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Jiangyin Healthway International Trade Co., Ltd Independent Ingredients Supplier We provide custom synthesis and contract manufacturing from milligrams to metric tonnes. Jiangyin Healthway International Trade Co., Ltd is a professional company, main engaged in manufacturing and exporting aroma chemicals ,food additives , cosmetic ingredient ,pharmaceutical intermediates & other fine chemicals; especially on aroma chemicals , as the major manufacturer of heterocyclic and sulphur aroma compounds , we are the leading independent ingredients supplier to the flavour and fragrance industries in China, can offer hundreds of different high quality aroma chemicals. Email: Info Email: Sales Voice: 86-510-86023169 Fax: 86-510-86023170 Mobile 0086-13093133011 Services Biochemical Natural Food Colour New functional food ingredients Product(s): HLC-412 Sodium Pyrrolidone Carboxylate
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| CAS Number: | 28874-51-3 |  3D/inchi
|
| ECHA EINECS - REACH Pre-Reg: | 249-277-1 | |
| FDA UNII: | 1V74VH163T | |
| Molecular Weight: | 151.09718928 | |
| Formula: | C5 H6 N Na O3 | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: cosmetic agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
Physical Properties:
| Assay: | 95.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Boiling Point: | 453.00 to 454.00 °C. @ 760.00 mm Hg (est) |
| Vapor Pressure: | 0.000000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 442.00 °F. TCC ( 227.80 °C. ) (est) |
| logP (o/w): | -2.387 (est) |
| Soluble in: | |
| water, 3.799e+005 mg/L @ 25 °C (est) | |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| CosIng: | cosmetic data |
| Cosmetic Uses: |
antistatic agents hair conditioning humectants skin conditioning |
Suppliers:
| BOC Sciences |
| For experimental / research use only. |
| sodium (2S)-5-oxopyrrolidine-2-carboxylate 98% |
| Jarchem Industries |
| Aminosyl™ NL50
Odor: characteristic Use: A natural moisturizing factor (NMF) that provides stronger hydrating power than glycerin, sorbitol or propanediol. Broad application ranging from creams and lotions to shampoos. |
| Jiangyin Healthway |
| Sodium Pyrrolidone Carboxylate |
| New functional food ingredients |
Safety Information:
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
|
oral-mouse LD50 10400 mg/kg International Journal of Toxicology. Vol. 18(Suppl | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | cosmetic agents | ||
| Recommendation for (S)-sodium PCA usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for (S)-sodium PCA flavor usage levels up to: | |||
| not for flavor use. | |||
Safety References:
| EPI System: | View |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 23668602 |
| National Institute of Allergy and Infectious Diseases: | Data |
| sodium (2S)-5-oxopyrrolidine-2-carboxylate | |
| Chemidplus: | 0028874513 |
References:
| sodium (2S)-5-oxopyrrolidine-2-carboxylate | |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 23668602 |
| Pubchem (sid): | 135050743 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| HMDB (The Human Metabolome Database): | Search |
| ChemSpider: | View |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| antistatic agents | ||
| humectants |
Occurrence (nature, food, other): note
| not found in nature |
Synonyms:
| ajidew NL-50 | |
| aminosyl NL50 | |
| bio-plex NMF | |
| bio-plex NMF-YD | |
| PCA soda | |
| L- | PCA-Na |
| 5-oxo-L- | proline monosodium salt |
| L-5-oxo | proline monosodium salt |
| L- | proline, 5-oxo-, monosodium salt |
| proline, 5-oxo-, monosodium salt, L- (8CI) | |
| L- | proline, 5-oxo-, sodium salt (1:1) |
| (2S)-5-oxo | pyrrolidine-2-carboxylic acid, sodium salt |
| L- | pyrrolidone-5-carboxylic acid |
| sodium (2S)-5-oxopyrrolidine-2-carboxylate | |
| sodium 5-oxo-L-prolinate | |
| sodium 5-oxo-laevo-prolinate | |
| sodium L-pyroglutamate | |
| sodium L-pyrrolidonecarboxylate | |
| sodium pidolate |