sodium ethylparaben
benzoic acid, 4-hydroxy-, ethyl ester, sodium salt
 
Notes:
None found
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CAS Number: 35285-68-8Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg: 252-487-6
FDA UNII: Z0D00IVA10
Nikkaji Web: J42.047F
Molecular Weight: 188.15809928
Formula: C9 H9 Na O3
NMR Predictor: Predict (works with chrome or firefox)
Category: preservatives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
 FDA/DG SANTE Petitions, Reviews, Notices:
EU SANCO p-hydroxybenzoates (PHB) View - review
EU SANCO Sodium ethyl p-hydroxybenzoate View - review
DG SANTE Food Additives: sodium ethyl p-hydroxybenzoate
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Soluble in:
 water, 2.656e+005 mg/L @ 25 °C (est)
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: preservatives
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Suppliers:
EMD Millipore
For experimental / research use only.
Ethyl 4-hydroxybenzoate sodium salt
Kingyoung Bio Technical
Sodium Ethylparaben
Matrix Scientific
For experimental / research use only.
Sodium 4-(ethoxycarbonyl)phenolate, 95+%
Nanjing Jiancheng Chemical
Sodium Ethyl P-hydroxybenzoate
Odor: characteristic
Use: Sodium ethyl p-hydroxybenzoate is widely used in food and pharmaceutical and textile industry for its antiseptic property. It is also can be used in other industries such as cosmetics, feed and so on.
Santa Cruz Biotechnology
For experimental / research use only.
Sodium ethyl p-hydroxybenzoate
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Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-mouse LD50  520 mg/kg
PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) BEHAVIORAL: ATAXIA BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 45, Pg. 260, 1956.

oral-mouse LD50  2500 mg/kg
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 45, Pg. 260, 1956.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: preservatives
Recommendation for sodium ethylparaben usage levels up to:
 not for fragrance use.
 
Recommendation for sodium ethylparaben flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 23681179
National Institute of Allergy and Infectious Diseases: Data
 sodium;4-ethoxycarbonylphenolate
Chemidplus: 0035285688
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References:
 sodium;4-ethoxycarbonylphenolate
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 35285-68-8
Pubchem (cid): 23681179
Pubchem (sid): 134998469
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
HMDB (The Human Metabolome Database): Search
FDA Listing of Food Additive Status: View
ChemSpider: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
 preservatives 
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
 benzoic acid, 4-hydroxy-, ethyl ester, sodium salt
 benzoic acid, p-hydroxy-, ethyl ester, sodium deriv.
 ethyl p-hydroxybenzoate, sodium salt
 ethylparaben sodium
 ethylparaben, sodium salt
4-hydroxybenzoic acid, ethyl ester, sodium salt
 sodium 4-ethoxycarbonyl phenoxide
 sodium 4-ethoxycarbonylphenoxide
 sodium ethyl 4-hydroxybenzoate
 sodium ethyl p-hydroxybenzoate
 sodium ethyl paraben
 sodium;4-ethoxycarbonylphenolate
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Articles:
PubMed: Evaluating food additives as antifungal agents against Monilinia fructicola in vitro and in hydroxypropyl methylcellulose-lipid composite edible coatings for plums.
PubMed: Antifungal activity of food additives in vitro and as ingredients of hydroxypropyl methylcellulose-lipid edible coatings against Botrytis cinerea and Alternaria alternata on cherry tomato fruit.
PubMed: Surfactant and temperature effects on paraben transport through silicone membranes.
PubMed: Ovariectomized mouse uterotrophic assay of 36 chemicals.
PubMed: Analysis of daidzein in nanoparticles after oral co-administration with sodium caprate to rats by ultra-performance liquid chromatography-quadrupole-time-of-flight mass spectrometry.
PubMed: Application of vesicular coacervate phase for microextraction based on solidification of floating drop.
PubMed: Dissociation constants of parabens and limiting conductances of their ions in water.
PubMed: Simultaneous determination of electroactive and non-electroactive food preservatives by novel capillary electrophoresis with amperometric detection.
PubMed: Physicochemical interactions between drugs and superdisintegrants.
PubMed: [Studies for analyzing the prohibited ingredients such as cyproheptadine hydrochloride in cosmetics].
PubMed: Separation of preservatives in cosmetic products by micellar electrokinetic chromatography.
PubMed: Separation and determination of haloperidol, parabens and some of their degradation products by micellar electrokinetic chromatography.
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