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dihydrochloride salt of diethylene diamine
Notes:
Formerly used as a food additive; now no longer generally recognised as safe
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| CAS Number: | 142-64-3 |  3D/inchi
|
| Other(deleted CASRN): | 8049-00-1 | |
| ECHA EINECS - REACH Pre-Reg: | 205-551-2 | |
| FDA UNII: | 17VU4Z4W88 | |
| MDL: | MFCD00012754 | |
| Molecular Weight: | 159.05764000 | |
| Formula: | C4 H12 Cl2 N2 | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: nematocide
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
| FDA Mainterm (SATF): | 142-64-3 ; PIPERAZINE DIHYDROCHLORIDE |
Physical Properties:
| Appearance: | whit to cream powder (est) |
| Food Chemicals Codex Listed: | No |
| Melting Point: | 318.00 to 320.00 °C. @ 760.00 mm Hg |
| Boiling Point: | 149.30 °C. @ 760.00 mm Hg (est) |
| Vapor Pressure: | 4.050000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 121.00 °F. TCC ( 49.70 °C. ) (est) |
| logP (o/w): | -1.171 (est) |
| Soluble in: | |
| water, 1e+006 mg/L @ 25 °C (est) | |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| None found |
Suppliers:
| Sigma-Aldrich |
| For experimental / research use only. |
| Piperazine dihydrochloride hydrate purum, ≥97.0% (AT) |
| TCI AMERICA |
| For experimental / research use only. |
| Piperazine Dihydrochloride Monohydrate >98.0%(N) |
Safety Information:
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
|
oral-rat LD50 4900 mg/kg Guide to the Chemicals Used in Crop Protection. Vol. 6, Pg. 416, 1973. intraperitoneal-mouse LD50 1970 mg/kg LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION Japanese Journal of Pharmacology. Vol. 17, Pg. 475, 1967. | |
| Dermal Toxicity: | |
|
subcutaneous-mouse LD50 2030 mg/kg Arzneimittel-Forschung. Drug Research. Vol. 4, Pg. 649, 1954. | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | nematocide | ||
| Recommendation for piperazine dihydrochloride usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for piperazine dihydrochloride flavor usage levels up to: | |||
| not for flavor use. | |||
Safety References:
| EPI System: | View |
| NIOSH Pocket Guide: | search |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA GENetic TOXicology: | Search |
| EPA Substance Registry Services (TSCA): | 142-64-3 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 8893 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 3 |
| piperazine dihydrochloride | |
| Chemidplus: | 0000142643 |
| EPA/NOAA CAMEO: | hazardous materials |
| RTECS: | 142-64-3 |
References:
| piperazine dihydrochloride | |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 8893 |
| Pubchem (sid): | 134973402 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| FDA Substances Added to Food (formerly EAFUS): | View |
| FDA Indirect Additives used in Food Contact Substances: | View |
| CHEMBL: | View |
| HMDB (The Human Metabolome Database): | Search |
| FooDB: | FDB020382 |
| Export Tariff Code: | 2933.59.9500 |
| ChemSpider: | View |
| Formulations/Preparations: •piperazine dihydrochloride 53% base is popular in dry feed or drinking water anthelmintic medication. •pipertab 2: composition: each tablet contains: piperazine dihydrochloride equivalent to 50 mg piperazine base. available in 500 tablet bottles. pipertab 10: composition: each tablet contains: piperazine dihydrochloride equivalent to 250 mg piperazine base. •52% piperazine base grades | |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| None Found |
Occurrence (nature, food, other): note
| not found in nature |
Synonyms:
| diethylene diamine dihydrochloride | |
| dihydrochloride salt of diethylene diamine | |
| dowzene DHC | |
| piperazine, dihydrochloride | |
| piperazine, hydrochloride (1:2) |