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Category: cosmetic agents and indirect food additives: paper and paperboard components
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Food Chemicals Codex Listed: | No |
Organoleptic Properties:
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | cosmetic agents and indirect food additives: paper and paperboard components |
| Recommendation for ferric citrate usage levels up to: | | | not for fragrance use.
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| Recommendation for ferric citrate flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | citric acid, iron(3+) salt (1:1) | | 2- | hydroxypropane-1,2,3-tricarboxylate;iron(3+) | | | iron(III) citrate | | 1,2,3- | propanetricarboxylic acid, 2-hydroxy-, iron(3+) salt (1:1) | | | zerenex |
Articles:
| PubMed: | Visual detection technique for efficient screening and isolation of Salmonella based on a novel enrichment assay using chromatography membrane. |
| PubMed: | Microbial Metabolism Shifts Towards an Adverse Profile with Supplementary Iron in the TIM-2 In vitro Model of the Human Colon. |
| PubMed: | Dose-related effects of ferric citrate supplementation on endoplasmic reticular stress responses and insulin signalling pathways in streptozotocin-nicotinamide-induced diabetes. |
| PubMed: | Managing hyperphosphatemia in patients with chronic kidney disease on dialysis with ferric citrate: latest evidence and clinical usefulness. |
| PubMed: | Novel iron-based phosphate binders in patients with chronic kidney disease. |
| PubMed: | Prion protein functions as a ferrireductase partner for ZIP14 and DMT1. |
| PubMed: | Dietary polyunsaturated fatty acids and heme iron induce oxidative stress biomarkers and a cancer promoting environment in the colon of rats. |
| PubMed: | Cultivar variability of iron uptake mechanisms in rice (Oryza sativa L.). |
| PubMed: | Ferric citrate hydrate as a phosphate binder and risk of aluminum toxicity. |
| PubMed: | A 13-week subchronic toxicity study of ferric citrate in F344 rats. |
| PubMed: | Dietary iron supplements and Moringa oleifera leaves influence the liver hepcidin messenger RNA expression and biochemical indices of iron status in rats. |
| PubMed: | Enhancement of non-heme iron absorption by anchovy (Engraulis japonicus) muscle protein hydrolysate involves a nanoparticle-mediated mechanism. |
| PubMed: | Safety Assessment of Citric Acid, Inorganic Citrate Salts, and Alkyl Citrate Esters as Used in Cosmetics. |
| PubMed: | Role of ferric reductases in iron acquisition and virulence in the fungal pathogen Cryptococcus neoformans. |
| PubMed: | Dynamics in the rhizosphere and iron-uptake gene expression in peanut induced by intercropping with maize: role in improving iron nutrition in peanut. |
| PubMed: | Silencing the Menkes copper-transporting ATPase (Atp7a) gene in rat intestinal epithelial (IEC-6) cells increases iron flux via transcriptional induction of ferroportin 1 (Fpn1). |
| PubMed: | Effect of iron liposomes on anemia of inflammation. |
| PubMed: | Hepatocyte divalent metal-ion transporter-1 is dispensable for hepatic iron accumulation and non-transferrin-bound iron uptake in mice. |
| PubMed: | High bioavailability iron maize (Zea mays L.) developed through molecular breeding provides more absorbable iron in vitro (Caco-2 model) and in vivo (Gallus gallus). |
| PubMed: | Ferric citrate CYP2E1-independently promotes alcohol-induced apoptosis in HepG2 cells via oxidative/nitrative stress which is attenuated by pretreatment with baicalin. |
| PubMed: | Heme carrier protein 1 transports heme and is involved in heme-Fe metabolism. |
| PubMed: | Iron and zinc concentrations in grain and flour of winter wheat as affected by foliar application. |
| PubMed: | Accelerating glycolytic flux of Torulopsis glabrata CCTCC M202019 at high oxidoreduction potential created using potassium ferricyanide. |
| PubMed: | A thioredoxin reductase-like protein from the thermophile, Thermus scotoductus SA-01, displaying iron reductase activity. |
| PubMed: | Transport of iron bound to recombinant human lactoferrin from rice and iron citrate across Caco-2 cell monolayers. |
| PubMed: | Effects of glyphosate application on seed iron and root ferric (III) reductase in soybean cultivars. |
| PubMed: | Biodegradation of anthraquinone dyes by Shewanella sp. NTOU1 under anaerobic conditions. |
| PubMed: | Ascorbic acid uptake affects ferritin, Dcytb and Nramp2 expression in Caco-2 cells. |
| PubMed: | Involvement of 101F6, a homologue of cytochrome b561, in the reduction of ferric ions. |
| PubMed: | A cyclic AMP receptor protein-regulated cell-cell communication system mediates expression of a FecA homologue in Stenotrophomonas maltophilia. |
| PubMed: | Isolation of a soluble and membrane-associated Fe(III) reductase from the thermophile, Thermus scotoductus (SA-01). |
| PubMed: | Zip14 (Slc39a14) mediates non-transferrin-bound iron uptake into cells. |
| PubMed: | Rates of foliar penetration of chelated Fe(III): role of light, stomata, species, and leaf age. |
| PubMed: | Inhibition of iron uptake from iron salts and chelates by divalent metal cations in intestinal epithelial cells. |
| PubMed: | Oxidative stress and antioxidant status in mouse kidney: effects of dietary lipid and vitamin E plus iron. |
| PubMed: | Physiological modulation of iron metabolism in rainbow trout (Oncorhynchus mykiss) fed low and high iron diets. |
| PubMed: | Ferric citrate is half as effective as ferrous sulfate in meeting the iron requirement of juvenile tilapia, Oreochromis niloticus x O. aureus. |
| PubMed: | Iron bioavailability and utilization in rats are lower from lime-treated corn flour than from wheat flour when they are fortified with different sources of iron. |
| PubMed: | Mutagenicity and DNA-damaging activity caused by decomposed products of potassium sorbate reacting with ascorbic acid in the presence of Fe salt. |
| PubMed: | Molecular cloning and identification of UTR1 of a yeast Saccharomyces cerevisiae as a gene encoding an NAD kinase. |
| PubMed: | Enhanced iron uptake of Saccharomyces cerevisiae by heterologous expression of a tadpole ferritin gene. |
| PubMed: | The importance of the proportion of heme/nonheme iron in the diet to minimize the interference with calcium, phosphorus, and magnesium metabolism on recovery from nutritional ferropenic anemia. |
| PubMed: | Red meat and colon cancer: the cytotoxic and hyperproliferative effects of dietary heme. |
| PubMed: | Oxidative stress and antioxidant status in mouse liver: effects of dietary lipid, vitamin E and iron. |
| PubMed: | Effects of iron replenishment on iron, calcium, phosphorus and magnesium metabolism in iron-deficient rats. |
| PubMed: | Iron supplementation generates hydroxyl radical in vivo. An ESR spin-trapping investigation. |
| PubMed: | Reduction of exogenous ferric iron by a surface-associated ferric reductase of Listeria spp. |
| PubMed: | Reduction of Fe(III) is required for uptake of nonheme iron by Caco-2 cells. |
| PubMed: | Tumorigenicity study of ferric citrate administered orally to mice. |
| PubMed: | Induction of oxidative single- and double-strand breaks in DNA by ferric citrate. |
| PubMed: | Heat resistance of Listeria monocytogenes by two recovery media used with and without cold preincubation. |
| PubMed: | Development of an improved chemically defined minimal medium for Listeria monocytogenes. |
| PubMed: | Effect of dietary fat on growth of MCF-7 and MDA-MB231 human breast carcinomas in athymic nude mice: relationship between carcinoma growth and lipid peroxidation product levels. |
| PubMed: | Development of a protein-free medium with ferric citrate substituting transferrin for the cultivation of mouse-mouse hybridomas. |
| PubMed: | Effect of endotoxin on colonisation of Campylobacter jejuni in infant mice. |
| PubMed: | Effect of excess dietary iron as ferrous sulfate and ferric citrate on tissue mineral composition of sheep. |
| PubMed: | [The determination of iron in ammoniacal ferric citrate and in syrups that contain it]. |
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