vanadyl sulfate
oxo[sulfato(2-)-O]-vanadium
 
Notes:
None found
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CAS Number: 27774-13-6Picture of molecule3D/inchi
Other(deleted CASRN): 102500-64-1
ECHA EINECS - REACH Pre-Reg: 248-652-7
FDA UNII: 6DU9Y533FA
Molecular Weight: 163.00250000
Formula: O5 S V
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome or firefox)
Category: nutrient supplements
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Assay: 98.00 to 100.00 % 
Food Chemicals Codex Listed: No
Boiling Point: 330.00 °C. @ 760.00 mm Hg (est)
Vapor Pressure: 0.000034 mmHg @ 25.00 °C. (est)
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
logP (o/w): -1.031 (est)
Soluble in:
 water
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
 None found
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-mouse LD50  44.988 mg/kg
Comptes Rendus Hebdomadaires des Seances, Academie des Sciences. Vol. 256, Pg. 1043, 1963.

intraperitoneal-mouse LD50  44988 ug/kg
Comptes Rendus Hebdomadaires des Seances, Academie des Sciences. Vol. 256, Pg. 1043, 1963.

intravenous-rabbit LDLo  16 mg/kg
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
American Journal of Syphilis and Neurology. Vol. 1, Pg. 347, 1917.

Dermal Toxicity:
skin-rabbit LD50 4450 mg/kg
Acute Toxicity Data. Journal of the American College of Toxicology, Part B. Vol. 1, Pg. 712, 1992.

subcutaneous-mouse LD50 560 mg/kg
Acute Toxicity Data. Journal of the American College of Toxicology, Part B. Vol. 1, Pg. 712, 1992.

subcutaneous-guinea pig LDLo 31 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
American Journal of Syphilis and Neurology. Vol. 1, Pg. 347, 1917.

subcutaneous-mouse LD50 560 mg/kg
Russian Pharmacology and Toxicology Vol. 34, Pg. 135, 1971.

subcutaneous-rat LDLo 140 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
American Journal of Syphilis and Neurology. Vol. 1, Pg. 347, 1917.

Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: nutrient supplements
Recommendation for vanadyl sulfate usage levels up to:
 not for fragrance use.
 
Recommendation for vanadyl sulfate flavor usage levels up to:
 not for flavor use.
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Safety References:
European Food Safety Authority (EFSA) reference(s):
Vanadium citrate, bismaltolato oxo vanadium and bisglycinato oxo vanadium added for nutritional purposes to foods for particular nutritional uses and foods (including food supplements) intended for the general population and vanadyl sulphate, vanadium pentoxide and ammonium monovanadate added for nutritional purposes to food supplements [1] - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food
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EPI System: View
ClinicalTrials.gov: search
Chemical Carcinogenesis Research Information System: Search
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA Substance Registry Services (TSCA): 27774-13-6
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 34007
National Institute of Allergy and Infectious Diseases: Data
 oxovanadium(2+) sulfate
Chemidplus: 0027774136
EPA/NOAA CAMEO: hazardous materials
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References:
 oxovanadium(2+) sulfate
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 27774-13-6
Pubchem (cid): 34007
Pubchem (sid): 134996279
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEBI: View
HMDB (The Human Metabolome Database): Search
FDA Listing of Food Additive Status: View
ChemSpider: View
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
oxo[sulfato(2-)-O]-vanadium
oxosulfatovanadium(IV)
 vanadin(IV) oxide sulfate
 vanadium (IV) oxide sulphate
 vanadium oxide sulfate (VO(SO4))
 vanadium oxide sulphate
 vanadium oxysulfate
 vanadium, oxo(sulfato(2-)-O)-
 vanadium, oxysulfato-
oxidovanadium(2+) sulfate
oxovanadium(2+) sulfate
oxovanadium(IV) sulfate
 vanadyl sulfate (VO(SO4))
 vanadyl sulfate [UN2931] [Poison]
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Articles:
PubMed: Quantitative Assessment of Proliferative Effects of Oral Vanadium on Pancreatic Islet Volumes and Beta Cell Numbers of Diabetic Rats.
PubMed: Novel water soluble neutral vanadium(IV)-antibiotic complex: Antioxidant, immunomodulatory and molecular docking studies.
PubMed: Iron diminishes the in vitro biological effect of vanadium.
PubMed: Synthesis, characterization, and efficacy evaluation of a new anti-diabetic vanadyl(II) thiamine hydrochloride complex in streptozotocin-induced diabetic rats.
PubMed: Nonselective mevalonate kinase inhibitor as a novel class of antibacterial agents.
PubMed: Novel vanadyl complexes of alginate saccharides: synthesis, characterization, and biological activities.
PubMed: Solid-state transformation of single precursor vanadium complex nanostructures to V₂O₅ and VO₂: catalytic activity of V₂O₅ for oxidative coupling of 2-naphthol.
PubMed: Trophic actions of oral vanadium and improved glycemia on the pancreatic beta-cell ultrastructure of streptozotocin-induced diabetic rats.
PubMed: α-Hydroxy coordination of mononuclear vanadyl citrate, malate and S-citramalate with N-heterocycle ligand, implying a new protonation pathway of iron-vanadium cofactor in nitrogenase.
PubMed: Dynamic nuclear polarization enhancement of protons and vanadium-51 in the presence of pH-dependent vanadyl radicals.
PubMed: Vanadyl sulfate treatment stimulates proliferation and regeneration of beta cells in pancreatic islets.
PubMed: Electrochemical codeposition of vanadium oxide and polypyrrole for high-performance supercapacitor with high working voltage.
PubMed: Ameliorative effect of vanadium on oxidative stress in stomach tissue of diabetic rats.
PubMed: Does the relief of glucose toxicity act as a mediator in proliferative actions of vanadium on pancreatic islet beta cells in streptozocin diabetic rats?
PubMed: Transformation of cellulose and its derived carbohydrates into formic and lactic acids catalyzed by vanadyl cations.
PubMed: Thymine vanadyl(II) compound as a diabetic drug model: chemical spectroscopic and antimicrobial assessments.
PubMed: Effects of vanadium (III, IV, V)-chlorodipicolinate on glycolysis and antioxidant status in the liver of STZ-induced diabetic rats.
PubMed: Protective effect of vanadyl sulfate on skin injury in streptozotocin-induced diabetic rats.
PubMed: [Anticancer activity of oxovanadium compounds].
PubMed: Coordination chemistry may explain pharmacokinetics and clinical response of vanadyl sulfate in type 2 diabetic patients.
PubMed: Synthesis, characterization and cell viability test of six vanadyl complexes with acetylacetonate derivatives.
PubMed: Long- term efficacy and safety of vanadium in the treatment of type 1 diabetes.
PubMed: Effects of vanadium complexes supplementation on V, Fe, Cu, Zn, Mn, Ca and K concentration in STZ diabetic rat's spleen.
PubMed: Protective effect of vanadyl sulfate on skin injury in streptozotocin-induced diabetic rats.
PubMed: Reduction of acrylamide formation by vanadium salt in potato French fries and chips.
PubMed: Anti-diabetic effects of a series of vanadium dipicolinate complexes in rats with streptozotocin-induced diabetes.
PubMed: Improvement in the calibration time of absolute emission rate of radioisotopic neutron sources using vanadyl sulfate bath.
PubMed: Biochemical and medical importance of vanadium compounds.
PubMed: Vanadium isotopic composition of the sea squirt (Ciona savignyi).
PubMed: Increased glutathione synthesis following Nrf2 activation by vanadyl sulfate in human chang liver cells.
PubMed: Vanadium compounds affect growth and morphology of human rhabdomyosarcoma cell line.
PubMed: [N'-(3-Eth-oxy-2-oxidobenzyl-idene-κO)-4-methyl-benzohydrazidato-κO,N'](methano-lato-κO)oxidovanadium(V).
PubMed: (Methano-lato-κO)[N'-(3-meth-oxy-2-oxidobenzyl-idene-κO)-4-nitro-benzo-hydrazidato-κN',O]oxidovanadium(V).
PubMed: (Methanol-κO)(methano-lato-κO)oxido{N'-[1-(2-oxidonaphthalen-1-yl-κO)ethyl-idene]nicotinohydrazidato-κN',O}vanadium(V).
PubMed: {4-Dimethyl-amino-N'-[1-(2-oxidophen-yl)ethyl-idene]benzohydrazidato}(methano-lato)oxidovanadium(V).
PubMed: Jeju ground water containing vanadium enhances antioxidant systems in human liver cells.
PubMed: Influence of vanadium supplementation on oxidative stress factors in the muscle of STZ-diabetic rats.
PubMed: Pancreatic islet beta cell protective effect of oral vanadyl sulphate in streptozotocin-induced diabetic rats, an ultrastructure study.
PubMed: Lipophilicity of kinetically labile metal complexes through the example of antidiabetic Zn(II) and VO(IV) compounds.
PubMed: Efficient aerobic oxidation of 5-hydroxymethylfurfural to 2,5-diformylfuran, and synthesis of a fluorescent material.
PubMed: Enantioselective aerobic oxidation of α-hydroxy-ketones catalyzed by oxidovanadium(V) methoxides bearing chiral, N-salicylidene-tert-butylglycinates.
PubMed: Sodium tungstate and vanadyl sulfate effects on blood pressure and vascular prostanoids production in fructose-overloaded rats.
PubMed: Identification of a new anti-diabetic agent by combining VOSO4 and vitamin E in a single molecule: studies on its spectral, thermal and pharmacological properties.
PubMed: DNA interactions and promotion in antibacterial activities of ciprofloxacin drug due to formation of mixed-ligand complexes of oxovanadium(IV).
PubMed: Bis- and tris(pyridyl)amine-oxidovanadium complexes: characteristics and insulin-mimetic potential.
PubMed: Vanadium (vanadyl sulfate). Monograph.
PubMed: Anti-diabetic effects of sodium 4-amino-2,6-dipicolinatodioxovanadium(V) dihydrate in streptozotocin-induced diabetic rats.
PubMed: Vanadium treatment of type 2 diabetes: a view to the future.
PubMed: Evaluation of insulin-mimetic activities of vanadyl and zinc(II) complexes from the viewpoint of heterocyclic bidentate ligands.
PubMed: Calorimetric studies of the interaction between the insulin-enhancing drug candidate bis(maltolato)oxovanadium(IV) (BMOV) and human serum apo-transferrin.
PubMed: Effect of vanadium on insulin sensitivity in patients with impaired glucose tolerance.
PubMed: Bis(alpha-furancarboxylato)oxovanadium(IV) prevents and improves dexamethasone-induced insulin resistance in 3T3-L1 adipocytes.
PubMed: The effect of vanadyl sulphate (VOSO4) on autocrine growth of human epithelial cancer cell lines.
PubMed: Cardioprotective effect of vanadyl sulfate on ischemia/reperfusion-induced injury in rat heart in vivo is mediated by activation of protein kinase B and induction of FLICE-inhibitory protein.
PubMed: Influence of field and experimental exposure of mussels (Mytilus sp.) to nickel and vanadium on metallothionein concentration.
PubMed: [Effect of vanadium compounds on the growth and production of coumarins in the suspension culture of Angelica archangelica L].
PubMed: Enzymatic activities in brains of diabetic rats treated with vanadyl sulphate and sodium tungstate.
PubMed: DNA cleavage by new oxovanadium(IV) complexes of N-salicylidene alpha-amino acids and phenanthroline bases in the photodynamic therapy window.
PubMed: The antilipolytic action of bis(alpha-furancarboxylato)oxovanadium(IV) in adipocytes.
PubMed: Comparison of the effect of VOSO4, Na3VO4 and NaVO3 on proliferation, viability and morphology of H35-19 rat hepatoma cell line.
PubMed: Effect of tiron and its combination with nutritional supplements against vanadium intoxication in female albino rats.
PubMed: Antidiabetic activity of the orally effective vanadyl-poly (gamma-glutamic acid) complex in streptozotocin(STZ)-induced type 1 diabetic mice.
PubMed: Model-based or algorithm-based? Statistical evidence for diabetes and treatments using gene expression.
PubMed: Evaluation of genotoxicity of oral exposure to tetravalent vanadium in vivo.
PubMed: Vanadyl sulfate, taurine, and combined vanadyl sulfate and taurine treatments in diabetic rats: effects on the oxidative and antioxidative systems.
PubMed: The role of vanadium in the chemical defense of the solitary tunicate, Phallusia nigra.
PubMed: 2-Acetyl-1,3-cyclopentanedione-oxovanadium(IV) complexes. Acidity and implications for gastrointestinal absorption.
PubMed: Interaction of vanadyl (VO2+) with ligands containing serine, tyrosine, and threonine.
PubMed: Vanadyl sulfate protects against streptozotocin-induced morphological and biochemical changes in rat aorta.
PubMed: Enhanced rosmarinic acid production by Lavandula vera MM cell suspension culture through elicitation with vanadyl sulfate.
PubMed: Reduction of oxidative stress induced vanadium toxicity by complexing with a flavonoid, quercetin: a pragmatic therapeutic approach for diabetes.
PubMed: Diabetes-altered gene expression in rat skeletal muscle corrected by oral administration of vanadyl sulfate.
PubMed: Oxovanadium(IV) complexes of hydrazides: potential antifungal agents.
PubMed: Vanadyl sulfate administration protects the streptozotocin-induced oxidative damage to brain tissue in rats.
PubMed: Vanadium and insulin increase adiponectin production in 3T3-L1 adipocytes.
PubMed: Inhibition of cyclic AMP dependent protein kinase by vanadyl sulfate.
PubMed: Chiral N-salicylidene vanadyl carboxylate-catalyzed enantioselective aerobic oxidation of alpha-hydroxy esters and amides.
PubMed: Effect of vanadyl sulfate on the status of lipid parameters and on stomach and spleen tissues of streptozotocin-induced diabetic rats.
PubMed: Comparative study on the preventing effects of oral vanadyl sulfate and dietary restriction on the age-related glucose intolerance in rats.
PubMed: Improved Taxol production by combination of inducing factors in suspension cell culture of Taxus baccata.
PubMed: Decavanadate interacts with microsomal NADH oxidation system and enhances cytochrome c reduction.
PubMed: Inhibition of vagally mediated immune-to-brain signaling by vanadyl sulfate speeds recovery from sickness.
PubMed: Protective effect of vanadyl sulfate on the pancreas of streptozotocin-induced diabetic rats.
PubMed: Organo-vanadium compounds are potent activators of the protein kinase B signaling pathway and protein tyrosine phosphorylation: mechanism of insulinomimesis.
PubMed: The effects of peroxovanadate and peroxovanadyl on glucose metabolism in vivo and identification of signal transduction proteins involved in the mechanism of action in isolated soleus muscle.
PubMed: Effect of bis[curcumino]oxovanadium complex on non-diabetic and streptozotocin-induced diabetic rats.
PubMed: Effect of insulin-mimetic vanadyl sulfate on cytochrome P450 2E1-dependent p-nitrophenol hydroxylation in the liver microsomes of streptozotocin-induced type 1 diabetic rats.
PubMed: [Effect of vanadyl sulfate (VOSO4) on the production of flavonoids by the culture Ononis arvensis L. in vitro].
PubMed: Effects of STZ-induced diabetes and its treatment with vanadyl sulphate on cyclosporine A-induced nephrotoxicity in rats.
PubMed: Effects of vanadyl sulfate on liver of streptozotocin-induced diabetic rats.
PubMed: Divalent metal transporter-1 decreases metal-related injury in the lung.
PubMed: Improvement of diabetic states in streptozotocin-induced type 1 diabetic rats by vanadyl sulfate in enteric-coated capsules.
PubMed: New insights into the interactions of serum proteins with bis(maltolato)oxovanadium(IV): transport and biotransformation of insulin-enhancing vanadium pharmaceuticals.
PubMed: Formation of an oxo-radical of peroxovanadate during reduction of diperoxovanadate with vanadyl sulfate or ferrous sulfate.
PubMed: Differential effects of sodium tungstate and vanadyl sulfate on vascular responsiveness to vasoactive agents and insulin sensitivity in fructose-fed rats.
PubMed: [Comparative assessment of cell mechanisms of the antidiabetic action of a new organic derivative of oxovanadium(IV) and vanadyl sulfate].
PubMed: Vanadyl sulfate ameliorates insulin resistance and restores plasma dehydroepiandrosterone-sulfate levels in fructose-fed, insulin-resistant rats.
PubMed: Influence of vanadyl sulphate [VOSO4] on biochemical activity and morphology of control and streptozotocin-diabetic rat liver Golgi complexes.
PubMed: Insulin-mimetic vanadyl(IV) complexes as evaluated by both glucose-uptake and inhibition of free fatty acids (FFA)-release in isolated rat adipocytes.
PubMed: Vanadyl sulfate inhibits NO production via threonine phosphorylation of eNOS.
PubMed: Pharmacokinetic study and trial for preparation of enteric-coated capsule containing insulinomimetic vanadyl compounds: implications for clinical use.
PubMed: Prolongation of insulin-induced activation of mitogen-activated protein kinases ERK 1/2 and phosphatidylinositol 3-kinase by vanadyl sulfate, a protein tyrosine phosphatase inhibitor.
PubMed: Vanadium(IV) and vanadium(V) complexes of salicyladimine ligands.
PubMed: A new family of insulin-mimetic vanadium complexes derived from 5-carboalkoxypicolinates.
PubMed: Effects of vanadyl sulfate on kidney in experimental diabetes.
PubMed: Vanadyl sulfate can differentially damage DNA in human lymphocytes and HeLa cells.
PubMed: Effects of some vanadyl coordination compounds on the in vitro insulin release from rat pancreatic islets.
PubMed: Vanadate and rapamycin synergistically enhance insulin-stimulated glucose uptake.
PubMed: Effect of chromium on apolipoprotein A-I expression in HepG2 cells.
PubMed: Short-term inhalation of particulate transition metals has little effect on the electrocardiograms of dogs having preexisting cardiac abnormalities.
PubMed: Effect of acute and short-term administration of vanadyl sulphate on insulin sensitivity in healthy active humans.
PubMed: Preparation and characterization of vanadyl complexes with bidentate maltol-type ligands; in vivo comparisons of anti-diabetic therapeutic potential.
PubMed: Mitochondrial oxidant production by a pollutant dust and NO-mediated apoptosis in human alveolar macrophage.
PubMed: Inorganic-organic hybrids derived from oxovanadium sulfate motifs: synthesis and characterization of [VIVO(mu 3-SO4)(2,2'-bpy)]infinity.
PubMed: A new concept: the use of vanadium complexes in the treatment of diabetes mellitus.
PubMed: Enteric-coating capsulation of insulinomimetic vanadyl sulfate enhances bioavailability of vanadyl species in rats.
PubMed: Influence of chelation and oxidation state on vanadium bioavailability, and their effects on tissue concentrations of zinc, copper, and iron.
PubMed: A fluorescent compound for glucose uptake measurements in isolated rat cardiomyocytes.
PubMed: Vanadium pharmacokinetics and oral bioavailability upon single-dose administration of vanadyl sulfate to rats.
PubMed: Activation of EGF receptors mediates pulmonary vasoconstriction induced by residual oil fly ash.
PubMed: Conformation changes in brain calcineurin in diabetic rats with or without treatment with vanadyl sulfate.
PubMed: Bis(6-ethylpicolinato)oxovanadium(IV) complex with normoglycemic activity in KK-A(y) mice.
PubMed: Dexamethasone-induced insulin resistance and pancreatic adaptive response in aging rats are not modified by oral vanadyl sulfate treatment.
PubMed: Pharmacokinetic study on gastrointestinal absorption of insulinomimetic vanadyl complexes in rats by ESR spectroscopy.
PubMed: Effect of vanadium(IV) compounds in the treatment of diabetes: in vivo and in vitro studies with vanadyl sulfate and bis(maltolato)oxovandium(IV).
PubMed: Decrease of hypothalamic neuropeptide Y gene expression by vanadyl sulfate in streptozotocin-induced diabetic rats.
PubMed: In vitro study of the insulin-like action of vanadyl-pyrone and -pyridinone complexes with a VO(O4) coordination mode.
PubMed: Treatment of diabetes with vanadium salts: general overview and amelioration of nutritionally induced diabetes in the Psammomys obesus gerbil.
PubMed: Vanadyl sulfate improves hepatic and muscle insulin sensitivity in type 2 diabetes.
PubMed: Guanine versus deoxyribose damage in DNA oxidation mediated by vanadium(IV) and vanadium(V) complexes.
PubMed: ENDOR studies of VO2+: probing protein-metal ion interactions in nephrocalcin.
PubMed: (NH4)3
PubMed: The formation of reactive oxygen species catalyzed by neutral, aqueous extracts of NIST ambient particulate matter and diesel engine particles.
PubMed: Vanadium interferes with siderophore-mediated iron uptake in Pseudomonas aeruginosa.
PubMed: Characterization of fine particulate matter produced by combustion of residual fuel oil.
PubMed: Insulin resistance and the modulation of rat cardiac K(+) currents.
PubMed: Statistical analysis of elicitation strategies for thiarubrine A production in hairy root cultures of Ambrosia artemisiifolia.
PubMed: Comparative erythropoietic effects of three vanadium compounds.
PubMed: Vanadium-induced kappaB-dependent transcription depends upon peroxide-induced activation of the p38 mitogen-activated protein kinase.
PubMed: Effects of low-dose VOSO(4) on age-related changes in glucose homeostasis in rats.
PubMed: NADH-dependent decavanadate reductase, an alternative activity of NADP-specific isocitrate dehydrogenase protein.
PubMed: Metabolic effects of vanadyl sulfate in humans with non-insulin-dependent diabetes mellitus: in vivo and in vitro studies.
PubMed: Distinct glucose lowering and beta cell protective effects of vanadium and food restriction in streptozotocin-diabetes.
PubMed: Normalization of hyperglycaemia by oral vanadyl sulfate does not reverse diabetes-induced protection against cisplatin nephrotoxicity in streptozotocin-diabetic rats.
PubMed: Phosphatidylinositol 3-kinase requirement in activation of the ras/C-raf-1/MEK/ERK and p70(s6k) signaling cascade by the insulinomimetic agent vanadyl sulfate.
PubMed: Arsenite exposure of cultured airway epithelial cells activates kappaB-dependent interleukin-8 gene expression in the absence of nuclear factor-kappaB nuclear translocation.
PubMed: [Insulin resistance: therapeutic approaches].
PubMed: Effect of oral vanadyl sulfate treatment on serum enzymes and lipids of streptozotocin-diabetic young rats.
PubMed: Antiinsulin receptor autoantibodies induce insulin receptors to constitutively associate with insulin receptor substrate-1 and -2 and cause severe cell resistance to both insulin and insulin-like growth factor I.
PubMed: A vanadyl sulfate-bovine serum albumin complex stimulates the release of lipoprotein lipase activity from isolated rat fat pads through an increase in the cellular content of cAMP and myo-inositol 1,4,5-trisphosphate.
PubMed: Nutritional supplements to increase muscle mass.
PubMed: Vanadium.
PubMed: Respiratory epithelial cells demonstrate lactoferrin receptors that increase after metal exposure.
PubMed: Transdermally delivered peroxovanadium can lower blood glucose levels in diabetic rats.
PubMed: Vanadium inhibition of serine and cysteine proteases.
PubMed: A new insulin-mimetic vanadyl complex, (N-pyridylmethylaspartate)oxovanadium(IV) with VO(N2O2) coordination mode, and evaluation of its effect on uptake of D-glucose by Ehrlich ascites tumour cells.
PubMed: Dietary supplements and the promotion of muscle growth with resistance exercise.
PubMed: Effects of vanadium complexes with organic ligands on glucose metabolism: a comparison study in diabetic rats.
PubMed: Solvent and temperature dependence of spin echo dephasing for chromium(V) and vanadyl complexes in glassy solution.
PubMed: Beneficial effects of a vanadium complex with cysteine, administered at low doses on benzo(alpha)pyrene-induced leiomyosarcomas in Wistar rats.
PubMed: Glucose transporter upregulation improves ischemic tolerance in hypertrophied failing heart.
PubMed: Vanadyl sulfate does not enhance insulin action in patients with type 1 diabetes.
PubMed: Vanadium and diabetes.
PubMed: [Genotoxic effects of vanadyl sulfate in Drosophila melanogaster].
PubMed: Vanadyl sulfate-stimulated glycogen synthesis is associated with activation of phosphatidylinositol 3-kinase and is independent of insulin receptor tyrosine phosphorylation.
PubMed: Inhibitory effect of vanadium compounds on glutamate dehydrogenase activity in mitochondria and hepatocytes isolated from rabbit liver.
PubMed: Vanadyl treatment normalizes submandibular salivary gland insulin-like immunoreactivity in streptozotocin-diabetic rats.
PubMed: Vanadyl ions stimulate K+ uptake into isolated perfused rat liver via the Na+/K+-pump by a tyrosine kinase-dependent mechanism.
PubMed: Kinetic analysis and comparison of uptake, distribution, and excretion of 48V-labeled compounds in rats.
PubMed: Improvement of impaired glucose tolerance by oral administration of vanadyl sulfate by gavage in streptozotocin-induced diabetic rats.
PubMed: Reducing agents mitigate protein synthesis inhibition mediated by vanadate and vanadyl compounds in reticulocyte lysates.
PubMed: Effects of vanadyl sulphate on glucose homeostasis in severe diabetes induced by streptozotocin in rats.
PubMed: Islet amyloid polypeptide in Psammomys obesus (sand rat): effects of nutritionally induced diabetes and recovery on low-energy diet or vanadyl sulfate treatment.
PubMed: Glucose-lowering properties of vanadium compounds: comparison of coordination complexes with maltol or kojic acid as ligands.
PubMed: Effects of oral vanadyl treatment on diabetes-induced alterations in the heart GLUT-4 transporter.
PubMed: Partial preservation of pancreatic beta-cells by vanadium: evidence for long-term amelioration of diabetes.
PubMed: Oral vanadyl sulphate does not affect blood cells, viscosity or biochemistry in humans.
PubMed: Characterization of vanadyl sulfate effect on vascular contraction: roles of calcium and tyrosine phosphorylation.
PubMed: Acute and chronic response to vanadium following two methods of streptozotocin-diabetes induction.
PubMed: Chronic vanadyl sulfate (VOSO4) oral treatment is associated with desensitization of VOSO4-induced contractile response in isolated gastric smooth muscle cells.
PubMed: Evidence for embryonic prostaglandin H synthase-catalyzed bioactivation and reactive oxygen species-mediated oxidation of cellular macromolecules in phenytoin and benzo[a]pyrene teratogenesis.
PubMed: Vanadyl sulphate differently influences insulin response to glucose in isolated pancreas of normal rats after in vivo or in vitro exposure.
PubMed: The effect of oral vanadyl sulfate on body composition and performance in weight-training athletes.
PubMed: Visualization of crystal-matrix structure. In situ demineralization of mineralized turkey leg tendon and bone.
PubMed: Vanadyl ion suppresses nitric oxide production from peritoneal macrophages of streptozotocin-induced diabetic mice.
PubMed: Effects of vanadyl sulfate on carbohydrate and lipid metabolism in patients with non-insulin-dependent diabetes mellitus.
PubMed: Phlorizin or vanadate treatment reverses impaired expression of albumin and hepatocyte nuclear factor 1 in diabetic rats.
PubMed: A characterization of pervanadate, an inducer of cellular tyrosine phosphorylation and inhibitor of gap junctional intercellular communication.
PubMed: Evidence for the distinct vanadyl(+4)-dependent activating system for manifesting insulin-like effects.
PubMed: Arsenic and chromium enhance transformation of bovine papillomavirus DNA-transfected C3H/10T1/2 cells.
PubMed: Vanadium-induced chemokine mRNA expression and pulmonary inflammation.
PubMed: Oral vanadyl sulfate improves insulin sensitivity in NIDDM but not in obese nondiabetic subjects.
PubMed: UV-B- and oxidative stress-induced increase in nicotinamide and trigonelline and inhibition of defensive metabolism induction by poly(ADP-ribose)polymerase inhibitor in plant tissue.
PubMed: Ethanol-dependent oxygen consumption and acetaldehyde formation during vanadyl oxidation by H2O2.
PubMed: Contractile effects of nanomolar concentrations of vanadyl sulphate on gastric smooth muscle cells isolated from normal or diabetic rats.
PubMed: The relationship between insulin and vanadium metabolism in insulin target tissues.
PubMed: Vanadium salts stimulate mitogen-activated protein (MAP) kinases and ribosomal S6 kinases.
PubMed: Increased potency of vanadium using organic ligands.
PubMed: Reversal of defective G-proteins and adenylyl cyclase/cAMP signal transduction in diabetic rats by vanadyl sulphate therapy.
PubMed: Modulation of insulin action by vanadate: evidence of a role for phosphotyrosine phosphatase activity to alter cellular signaling.
PubMed: Hypoglycemic effects of peroxovanadium compounds in Sprague-Dawley and diabetic BB rats.
PubMed: Roles of protein-tyrosine phosphatases in Stat1 alpha-mediated cell signaling.
PubMed: Skeletal muscle mitogen-activated protein kinases and ribosomal S6 kinases. Suppression in chronic diabetic rats and reversal by vanadium.
PubMed: Detection of vanadyl-nitrogen interaction in organs of the vanadyl-treated rat: electron spin echo envelope modulation study.
PubMed: L1 and N-CAM antibodies trigger protein phosphatase activity in growth cone-enriched membranes.
PubMed: Oral vanadyl sulfate improves hepatic and peripheral insulin sensitivity in patients with non-insulin-dependent diabetes mellitus.
PubMed: Vanadium salts induce cytogenetic effects in in vivo treated mice.
PubMed: Mechanism on insulin-like action of vanadyl sulfate: studies on interaction between rat adipocytes and vanadium compounds.
PubMed: Concentration-dependent glucose-lowering effects of oral vanadyl are maintained following treatment withdrawal in streptozotocin-diabetic rats.
PubMed: The effect of aluminum on the vanadium-mediated oxidation of NADH.
PubMed: The use of fluorescence in situ hybridization with a beta-satellite DNA probe for the detection of acrocentric chromosomes in vanadium-induced micronuclei.
PubMed: Comparison of the glucose-lowering properties of vanadyl sulfate and bis(maltolato)oxovanadium(IV) following acute and chronic administration.
PubMed: Vanadyl sulfate lowers plasma insulin and blood pressure in spontaneously hypertensive rats.
PubMed: Toxicity studies on one-year treatment of non-diabetic and streptozotocin-diabetic rats with vanadyl sulphate.
PubMed: Comparison of the effects of various vanadium salts on glucose homeostasis in streptozotocin-diabetic rats.
PubMed: Effect of vanadium compounds on calmodulin activity in experimental diabetes in rats.
PubMed: Beneficial effects of vanadyl sulfate administration on sugar metabolism in the senescent rat.
PubMed: The effect of vanadyl treatment on vascular responsiveness of streptozotocin-diabetic rats.
PubMed: Vanadyl sulfate prevents fructose-induced hyperinsulinemia and hypertension in rats.
PubMed: One-year treatment of non-diabetic and streptozotocin-diabetic rats with vanadyl sulphate did not alter blood pressure or haematological indices.
PubMed: One-year treatment of streptozotocin-induced diabetic rats with vanadyl sulphate.
PubMed: Studies of vanadyl sulfate as a glucose-lowering agent in STZ-diabetic rats.
PubMed: Multiple reactions in vanadyl-V(IV) oxidation by H2O2.
PubMed: The intensity of vanadium(V)-induced cytotoxicity and morphological transformation in BALB/3T3 cells is dependent on glutathione-mediated bioreduction to vanadium(IV).
PubMed: Phosphatase inhibitors, gap junctional intercellular communication and [125I]-EGF binding in hamster fibroblasts.
PubMed: Cytogenetic damage induced in human lymphocytes by four vanadium compounds and micronucleus analysis by fluorescence in situ hybridization with a centromeric probe.
PubMed: Beneficial effects of the oral administration of vanadyl sulphate on glucose metabolism in senescent rats.
PubMed: In vivo antidiabetic actions of naglivan, an organic vanadyl compound in streptozotocin-induced diabetes.
PubMed: Effect of vanadyl sulfate feeding on susceptibility to peroxidative change in diabetic rats.
PubMed: Long-term effectiveness of oral vanadyl sulphate in streptozotocin-diabetic rats.
PubMed: DNA cleavage by hydroxyl radicals generated in a vanadyl ion-hydrogen peroxide system.
PubMed: [Effects of vanadyl sulfate on osteopenia in streptozotocin-induced diabetic (STZD) rats. Comparison with those of insulin].
PubMed: Oxoanions stimulate in vitro ovulation and signal transduction pathways in goldfish (Carassius auratus) follicles.
PubMed: Characterization of oxygen free radicals generated during vanadate-stimulated NADH oxidation.
PubMed: Administration of vanadyl sulfate by gavage does not normalize blood glucose levels in streptozotocin-induced diabetic rats.
PubMed: Vanadate increases protein kinase C-induced phosphorylation of endogenous proteins of liver in vitro.
PubMed: Alternative staining methods for Lowicryl sections.
PubMed: Differential sensitivity of the brain ATP-dependent and GTP-dependent succinyl-CoA synthetase to vanadium ions. Developmental aspects.
PubMed: Phase determination by polarized dispersion in vanadyl sulfate pentahydrate.
PubMed: Evaluation of the efficacy of various chelating agents on urinary excretion and tissue distribution of vanadium in rats.
PubMed: Effectiveness of some chelating agents on distribution and excretion of vanadium in rats after prolonged oral administration.
PubMed: Antidiabetic action of vanadyl in rats independent of in vivo insulin-receptor kinase activity.
PubMed: Characteristics of histamine secretion from mast cells stimulated with sodium orthovanadate and other vanadium compounds.
PubMed: Genotoxicity of vanadium compounds in yeast and cultured mammalian cells.
PubMed: Lipid peroxidation and benzo(a)pyrene derivative co-oxygenation by environmental pollutants.
PubMed: Toxicological aspects of vanadyl sulphate on diabetic rats: effects on vanadium levels and pancreatic B-cell morphology.
PubMed: Insulin-like effect of vanadyl ion on streptozotocin-induced diabetic rats.
PubMed: Developmental toxicity of vanadium in mice after oral administration.
PubMed: Chelating agents in the treatment of acute vanadyl sulphate intoxication in mice.
PubMed: Peripheral erythrocyte levels, hemolysis and three vanadium compounds.
PubMed: Vanadium uptake by yeast cells.
PubMed: An assessment of the genotoxicity of vanadium.
PubMed: Tetravalent vanadium mediated oxidation of low density lipoprotein.
PubMed: Long-term effects of vanadyl treatment on streptozocin-induced diabetes in rats.
PubMed: Normal rat kidney cells secrete both phosphorylated and nonphosphorylated forms of osteopontin showing different physiological properties.
PubMed: Sustained prevention of myocardial and metabolic abnormalities in diabetic rats following withdrawal from oral vanadyl treatment.
PubMed: Oral vanadyl sulfate in treatment of diabetes mellitus in rats.
PubMed: Oxidation of NADH by vanadium compounds in the presence of thiols.
PubMed: Effects of vanadyl sulphate on ornithine decarboxylase and progesterone levels in the ovary of rat.
PubMed: Genetic evidence for an Azotobacter vinelandii nitrogenase lacking molybdenum and vanadium.
PubMed: Do vanadium ions exert any specific effect on brain protein phosphorylation.
PubMed: [Predicting the combined effect of metals using toxico-kinetic indices].
PubMed: Biphasic effect of vanadium salts on in vitro tumor colony growth.
PubMed: Inhibition by vanadate of cyclic AMP production in rat corpora lutea incubated in vitro.
PubMed: The effects of vanadium compounds on the activation of adenylate cyclase from rat adrenal membrane.
PubMed: Vanadium inhibits ACTH-mediated but not cyclic AMP-dependent adrenal steroidogenesis.
PubMed: ATP-dependent protease in bovine adrenal cortex. Tissue specificity, subcellular localization, and partial characterization.
PubMed: Vanadium exposure enhances lipid peroxidation in the kidney of rats and mice.
PubMed: Effect of vanadate and pyridoxal phosphate on S-adenosylmethionine.
PubMed: Acute toxicity of vanadium compounds in rats and mice.
PubMed: The stimulation of pp60v-src kinase activity by vanadate in intact cells accompanies a new phosphorylation state of the enzyme.
PubMed: Cytotoxic effect of vanadium and oil-fired fly ash on hamster tracheal epithelium.
PubMed: The effects of vanadate on 45Ca exchange and enzyme secretion in the rat exocrine pancreas.
PubMed: Dietary vanadyl(IV) sulfate inhibits chemically-induced mammary carcinogenesis.
PubMed: Chelate antidotes for sodium vanadate and vanadyl sulfate intoxication in mice.
PubMed: Vanadium ions stimulate DNA synthesis in Swiss mouse 3T3 and 3T6 cells.
PubMed: [Use of hydrolin and dimexide for experimental sensitization].
PubMed: The fate of cytoplasmic vanadium. Implications on (NA,K)-ATPase inhibition.
PubMed: Accumulation and depletion of vanadium in selected tissues of rats treated with vanadyl sulfate and sodium orthovanadate.
PubMed: Oxidative degradation pharmaceutically important phenothiazines II: Quantitative determination of promethazine and some degradation products.
PubMed: Effects of dietary vanadium in mallard ducks.
PubMed: Inhibition of ribonucleases by ribonucleotides and transition state analogs in cell-free extracts from Ehrlich ascites tumor cells.
PubMed: Vanadium compounds and ferrocyanide as ionic redox agents in photosynthesis.
PubMed: Growth effects of vanadium in the rat.
PubMed: [Therapeutic effect of vanadyl sulfate in experimental tuberculosis].
PubMed: Effect of Vanadium on Growth, Chemical Composition, and Metabolic Processes of Mature Sugar Beet (Beta vulgaris L.) Plants.
PubMed: [The influence of vanadyl sulfate on hypercholesterinemia following a single injection of cholesterin)].
PubMed: [ACETYLCHOLINE METABOLISM IN THE RAT BRAIN FOLLOWING THE COMBINED ACTION OF VANADYL SULFATE AND SOME PHENYLACETIC ACID DERIVATIVES].
PubMed: [Effect of the sodium salt of phenylethylacetic acid, vanadyl sulfate and their combinations on the pathogenesis and development of experimental atherosclerosis].
PubMed: Reduction of excess cholesterol in the rabbit aorta by inhibition of endogenous cholesterol synthesis.
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