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Category: natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Melting Point: | 234.00 °C. @ 760.00 mm Hg (est)
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| Boiling Point: | 438.03 °C. @ 760.00 mm Hg (est)
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| Vapor Pressure: | 4.800000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 426.00 °F. TCC ( 218.70 °C. ) (est)
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| logP (o/w): | -1.880 (est) |
| Soluble in: |
| | water, 6.877e+004 mg/L @ 25 °C (est) |
Organoleptic Properties:
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | natural substances and extractives |
| Recommendation for dextro-asparagine usage levels up to: | | | not for fragrance use.
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| Recommendation for dextro-asparagine flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| (2R)-2- | amino-3-carbamoylpropanoic acid | | (R)-2- | amino-3-carbamoylpropanoic acid | | (R)-2- | aminosuccinamic acid | | D-2- | aminosuccinamic acid | | D- | asparagin | | D- | asparagine | | dextro(-)- | asparagine monohydrate | | (2R)-2,4- | diamino-4-oxobutanoic acid |
Articles:
| PubMed: | Using D-Amino Acids to Delineate the Mechanism of Protein Folding: Application to Trp-cage. |
| PubMed: | Alloscardovia macacae sp. nov., isolated from the milk of a macaque (Macaca mulatta), emended description of the genus Alloscardovia and proposal of Alloscardovia criceti comb. nov. |
| PubMed: | In vivo evidence for a prodrug activation mechanism during colibactin maturation. |
| PubMed: | A prodrug resistance mechanism is involved in colibactin biosynthesis and cytotoxicity. |
| PubMed: | The discovery of stereoselectivity at biological receptors: Arnaldo Piutti and the taste of the asparagine enantiomers--history and analysis on the 125th anniversary. |
| PubMed: | A natural prodrug activation mechanism in nonribosomal peptide synthesis. |
| PubMed: | A sensitive and simple ultra-high-performance-liquid chromatography-tandem mass spectrometry based method for the quantification of D-amino acids in body fluids. |
| PubMed: | Acinetobacter strains IH9 and OCI1, two rhizospheric phosphate solubilizing isolates able to promote plant growth, constitute a new genomovar of Acinetobacter calcoaceticus. |
| PubMed: | Identification, biochemical characterization, and subcellular localization of allantoate amidohydrolases from Arabidopsis and soybean. |
| PubMed: | Degree of supersaturation-regulated chiral symmetry breaking in one crystal. |
| PubMed: | Identification of an essential gene responsible for D-Asp incorporation in the Lactococcus lactis peptidoglycan crossbridge. |
| PubMed: | Characterization of salt-tolerant glutaminase from Stenotrophomonas maltophilia NYW-81 and its application in Japanese soy sauce fermentation. |
| PubMed: | N-Acyl derivatives of Asn, new bacterial N-acyl D-amino acids with surfactant activity. |
| PubMed: | Biosensor for asparagine using a thermostable recombinant asparaginase from Archaeoglobus fulgidus. |
| PubMed: | pH and kinetic isotope effects in d-amino acid oxidase catalysis. |
| PubMed: | Structural basis for the activity and substrate specificity of Erwinia chrysanthemi L-asparaginase. |
| PubMed: | Purification and preliminary characterization of L-asparaginase from Erwinia aroideae NRRL B-138. |
| PubMed: | Multipin solid-phase synthesis of acyl 2, 3-diaminopropionic acid oligomers. |
| PubMed: | Determination of D-amino acids, derivatized with 4-fluoro-7-nitro-2,1,3-benzoxadiazole (NBD-F), in wine samples by high-performance liquid chromatography. |
| PubMed: | Quantification of D-aspartate in normal and Alzheimer brains. |
| PubMed: | Staphylococcal L-asparaginase: enzyme kinetics. |
| PubMed: | Purification and properties of an L-asparaginase from Cylindrocarpon obtusisporum MB-10. |
| PubMed: | Antiproliferative activity of L-asparaginase of Tetrahymena pyriformis on human breast cancer cell lines. |
| PubMed: | Characterization and partial purification of L-asparaginase from Corynebacterium glutamicum. |
| PubMed: | Purification and properties of a membrane-bound L-asparaginase of Tetrahymena pyriformis. |
| PubMed: | Substrate specificity of duckling hepatic and renal D-amino acid oxidase. |
| PubMed: | [A study on the bactericidal action of aspoxicillin against Escherichia coli]. |
| PubMed: | Age-dependent accumulation of protein residues which can be hydrolyzed to D-aspartic acid in human erythrocytes. |
| PubMed: | Incorporation of beta-fluoroasparagine into peptides prevents N-linked glycosylation. In vitro studies with synthetic fluoropeptides. |
| PubMed: | Modified ammonia electrode method to investigate D-asparagine breakdown by Campylobacter strains. |
| PubMed: | A specific L-asparaginase from Thermus aquaticus. |
| PubMed: | Antitumor activity of DL-threo-beta-fluoroasparagine against human leukemia cells in culture and L1210 cells in DBA mice. |
| PubMed: | Use of an ammonia electrode to study bacterial deamination of amino acids with special reference to D-asparagine breakdown by campylobacters. |
| PubMed: | Asparaginase II of Saccharomyces cerevisiae: positive selection of two mutations that prevent enzyme synthesis. |
| PubMed: | Conformational comparisons of oxytocin agonists, partial agonists, and antagonists using laser Raman and circular dichroism spectroscopy. Examination of 1-penicillamine and diastereoisomeric analogues. |
| PubMed: | Structure of bacillomycin D, a new antibiotic of the iturin group. |
| PubMed: | [Immobilization of Citrobacter L-asparaginase in polyacrylamide gel]. |
| PubMed: | [Synthesis and study of biospecific sorbents for isolating and purifying L-asparaginase from Escherichia coli]. |
| PubMed: | The separation of peptide hormone diastereoisomers by reverse phase high pressure liquid chromatography. Factors affecting separation of oxytocin and its diastereoisomers--structural implications. |
| PubMed: | Tumor inhibitory and non-tumor inhibitory L-asparaginases from Pseudomonas geniculata. |
| PubMed: | [Substrate specificity, inhibitors and kinetics of deamidase AG (asparaginase-glutaminase) from Pseudomonas fluorescens AG]. |
| PubMed: | Genetic and physiological relationships between L-asparaginase I and asparaginase II in Saccharomyces cerevisiae. |
| PubMed: | Purification and characterization of L-asparaginase with anti-lymphoma activity from Vibrio succinogenes. |
| PubMed: | Utilization of D-asparagine by Saccharomyces cerevisiae. |
| PubMed: | Purification and properties of L-asparaginase from Mycobacterium phlei. |
| PubMed: | The properties and large-scale production of L-asparaginase from citrobacter. |
| PubMed: | [Asparaginase and glutaminase activity in Pseudomonas fluorescens in continuous cultivation]. |
| PubMed: | (A-21-D-asparagine) sheep insulin, a diastereoisomer of the natural hormone. |
| PubMed: | [Purification of microbial asparaginases by the aid of affinity chromatography]. |
| PubMed: | "Dysgonic" strains of mycobacterium tuberculosis on Ogawa's egg medium isolated as pathogens from patients suffering from lung tuberculosis. II. Growth-inhibitory effects of D-asparagine, D-aspartic acid, Dl-serine, or L-serine against "dysgonic". |
| PubMed: | Synthesis and pharmacological activity of 4-d-glutamine-oxytocin, 5-d-asparagine-oxytocin, and 4-d-glutamine-5-d-asparagine-oxytocin. |
| PubMed: | Inhibition of L-asparaginase in extracts of Mycobacterium phlei by D-asparagine. |
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