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Category: pharmaceuticals / chemical synthisis
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Boiling Point: | 441.50 °C. @ 760.00 mm Hg (est)
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| Vapor Pressure: | 0.000000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 429.00 °F. TCC ( 220.80 °C. ) (est)
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| logP (o/w): | 5.081 (est) |
| Soluble in: |
| | water, 5.346 mg/L @ 25 °C (est) |
Organoleptic Properties:
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
intraperitoneal-mouse LD50 2210 mg/kg Gendai no Rinsho. Vol. 3, Pg. 259, 1969.
intravenous-mouse LD50 44 mg/kg Gendai no Rinsho. Vol. 3, Pg. 259, 1969.
oral-mouse LD50 3000 mg/kg Zentralblatt fuer Pharmazie, Pharmakotherapie und Laboratoriums-diagnostik. Vol. 109, Pg. 385, 1970.
oral-rabbit LD50 10000 mg/kg LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
CARDIAC: OTHER CHANGES Archives Internationales de Pharmacodynamie et de Therapie. Vol. 163, Pg. 284, 1966.
intraperitoneal-rat LD50 1680 mg/kg BEHAVIORAL: TREMOR
SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE
BEHAVIORAL: ATAXIA Gendai no Rinsho. Vol. 3, Pg. 259, 1969.
oral-rat LD50 6000 mg/kg BEHAVIORAL: TREMOR
SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE
BEHAVIORAL: ATAXIA Gendai no Rinsho. Vol. 3, Pg. 259, 1969.
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| Dermal Toxicity: |
subcutaneous-mouse LD50 > 14000 mg/kg Drugs in Japan Vol. 6, Pg. 737, 1982.
subcutaneous-rat LD50 > 14000 mg/kg Yakkyoku. Pharmacy. Vol. 35(1), Pg. -, 1984.
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | pharmaceuticals / chemical synthisis |
| Recommendation for bromhexine hydrochloride usage levels up to: | | | not for fragrance use.
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| Recommendation for bromhexine hydrochloride flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
| | 2,4-dibromo-6-[[cyclohexyl(methyl)amino]methyl]aniline;hydrochloride |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 5702220 |
| Pubchem (sid): | 135048886 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 2- | amino-3,5-dibromo-N-cyclohexyl-N-methylbenzenemethanamine monohydrochloride | | 2- | amino-3,5-dibromo-N-cyclohexyl-N-methylbenzylamine hydrochloride | | [(2- | amino-3,5-dibromophenyl)methyl]cyclohexylmethylamine, chloride | | 2- | amino-N-cyclohexyl-3,5-dibromo-N-methylbenzylamine hydrochloride | | | benzenemethanamine, 2-amino-3,5-dibromo-N-cyclohexyl-N-methyl-, hydrochloride (1:1) | | | benzenemethanamine, 2-amino-3,5-dibromo-N-cyclohexyl-N-methyl-, monohydrochloride | | | benzylamine, 2-amino-N-cyclohexyl-3,5-dibromo-N-methyl-, hydrochloride | | | bisolvon | | | bromhexine chloride | | | bromhexine HCl | | | bromhexinehydrochloride | | | bromohexine HCl | | | bromohexine hydrochloride | | N- | cyclohexyl-N-methyl-(2-amino-3,5-dibromobenzyl)ammonium chloride | | 2,4- | dibromo-6-[[cyclohexyl(methyl)amino]methyl]aniline;hydrochloride | | 2,4- | dibromo-6-{[cyclohexyl(methyl)amino]methyl}aniline hydrochloride (1:1) | | 3,5- | dibromo-Na-cyclohexyl-Na-methyltoluene-a,2-diamine Hydrochloride |
Articles:
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