aziridine
ethyleneimine
 
Notes:
None found
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CAS Number: 151-56-4Picture of molecule3D/inchi
Other: 99932-76-0
ECHA EINECS - REACH Pre-Reg: 206-022-9
FDA UNII: 54P5FEX9FH
Nikkaji Web: J2.966A
Beilstein Number: 0102380
XlogP3-AA: -0.40 (est)
Molecular Weight: 43.06885000
Formula: C2 H5 N
NMR Predictor: Predict (works with chrome or firefox)
Category: indirect food additives: adhesives and components of coatings
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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DG SANTE Food Contact Materials: ethyleneimine
FDA Mainterm (IAUFC):151-56-4 ; ETHYLENIMINE
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Physical Properties:
Appearance: colorless to pale yellow clear liquid (est)
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
Noble Molecular Research
For experimental / research use only.
Aziridine
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-mouse LD50  4 mg/kg
KIDNEY, URETER, AND BLADDER: URINE VOLUME INCREASED
British Journal of Pharmacology and Chemotherapy. Vol. 25, Pg. 223, 1965.

unreported-mouse LD50  15 mg/kg
British Journal of Cancer. Vol. 6, Pg. 160, 1952.

intraperitoneal-rat LD50  3500 ug/kg
KIDNEY, URETER, AND BLADDER: URINE VOLUME INCREASED
British Journal of Pharmacology and Chemotherapy. Vol. 21, Pg. 581, 1963.

oral-rat LD50  15 mg/kg
KIDNEY, URETER, AND BLADDER: OTHER CHANGES BEHAVIORAL: GENERAL ANESTHETIC GASTROINTESTINAL: OTHER CHANGES
Journal of Industrial Hygiene and Toxicology. Vol. 23, Pg. 259, 1941.

Dermal Toxicity:
skin-guinea pig LD50 14 mg/kg
Journal of Industrial Hygiene and Toxicology. Vol. 30, Pg. 63, 1948.

subcutaneous-rabbit LDLo 50 mg/kg
Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 10, Pg. 25, 1968.

Inhalation Toxicity:
inhalation-guinea pig LCLo 25 ppm/8H
KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)" LUNGS, THORAX, OR RESPIRATION: DYSPNEA LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA
Journal of Industrial Hygiene and Toxicology. Vol. 30, Pg. 2, 1948.

inhalation-mouse LC50 400 mg/m3/2H
BEHAVIORAL: MUSCLE WEAKNESS LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 8, Pg. 41, 1966.

inhalation-rabbit LCLo 100 mg/m3/2H
BLOOD: OTHER CHANGES LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BRAIN AND COVERINGS: OTHER DEGENERATIVE CHANGES
Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 8, Pg. 41, 1966.

inhalation-rat LC50 100 mg/m3/2H
"Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 67, 1982.

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Safety in Use Information:
Category: indirect food additives: adhesives and components of coatings
Recommendation for aziridine usage levels up to:
 not for fragrance use.
 
Recommendation for aziridine flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
EPA-Iris: IRIS
NIOSH International Chemical Safety Cards: search
NIOSH Pocket Guide: search
Chemical Carcinogenesis Research Information System: Search
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
Carcinogenic Potency Database: Search
EPA GENetic TOXicology: Search
EPA Substance Registry Services (TSCA): 151-56-4
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 9033
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 3
 aziridine
Chemidplus: 0000151564
EPA/NOAA CAMEO: hazardous materials
RTECS: 151-56-4
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References:
 aziridine
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 9033
Pubchem (sid): 134973425
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
FDA Indirect Additives used in Food Contact Substances:View
CHEBI: View
CHEMBL: View
KEGG (GenomeNet): C11687
HMDB (The Human Metabolome Database): Search
ChemSpider: View
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
 aziran
azacyclopropane
 dihydro-1H-azirine
 dimethylenimine
 ethylene imine
 ethyleneimine
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