sodium dimethyl dithiocarbamate
carbamodithioic acid, N,N-dimethyl-, sodium salt (1:1)
 
Notes:
Antimicrobial agent used in cane-sugar and beet-sugar mills
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      128-04-1 Sodium dimethyldithiocarbamate solution 95%
       
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      MP-004244 SODIUM DIMETHYL DITHIOCARBAMATE 41% (DMDTC)
       
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      D0716 Sodium Dimethyldithiocarbamate Dihydrate >98.0%(T)
       
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CAS Number: 128-04-1Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg: 205-011-6
FDA UNII: 769GO8W6QQ
Nikkaji Web: J55.519C
Beilstein Number: 3569024
MDL: MFCD00044839
Molecular Weight: 143.20758928
Formula: C3 H6 N Na S2
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome or firefox)
Category: control of microorganisms and as slimicides
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
FDA Mainterm (SATF):128-04-1 ; SODIUM DIMETHYLDITHIOCARBAMATE
FDA Regulation:
FDA PART 173 -- SECONDARY DIRECT FOOD ADDITIVES PERMITTED IN FOOD FOR HUMAN CONSUMPTION
Subpart D--Specific Usage Additives
Sec. 173.320 Chemicals for controlling microorganisms in cane-sugar and beet-sugar mills.


FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS
Subpart B--Substances for Use Only as Components of Adhesives
Sec. 175.105 Adhesives.


FDA PART 176 -- INDIRECT FOOD ADDITIVES: PAPER AND PAPERBOARD COMPONENTS
Subpart B--Substances for Use Only as Components of Paper and Paperboard
Sec. 176.300 Slimicides.


FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS
Subpart C--Substances for Use Only as Components of Articles Intended for Repeated Use
Sec. 177.2600 Rubber articles intended for repeated use.
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Boiling Point: 129.40 °C. @ 760.00 mm Hg (est)
Vapor Pressure: 10.200000 mmHg @ 25.00 °C. (est)
Flash Point: 90.00 °F. TCC ( 32.00 °C. ) (est)
logP (o/w): 0.745 (est)
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
BOC Sciences
For experimental / research use only.
Sodium dimethyldithiocarbamate solution 95%
ECSA Chemicals
SODIUM DIMETHYL DITHIOCARBAMATE 41% (DMDTC)
ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY
Santa Cruz Biotechnology
For experimental / research use only.
Sodium dimethyldithiocarbamate solution
Shiva Chemicals and Pharmaceuticals
SodiumDimethylDithiocarbamate(SDD/SDMC)
Sigma-Aldrich: Aldrich
For experimental / research use only.
Sodium dimethyldithiocarbamate solution ∼40% in H2O
Taminco (Eastman)
sodiumdimethyldithiocarbamate (SDDC)
TCI AMERICA
For experimental / research use only.
Sodium Dimethyldithiocarbamate Dihydrate >98.0%(T)
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Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50  1000 mg/kg
Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. Vol. -, Pg. 1029, 1966.

intraperitoneal-rat LD50  1000 mg/kg
Pharmazie. Vol. 27, Pg. 139, 1972.

oral-rabbit LD50  300 mg/kg
Toksikologicheskii Vestnik. Vol. (3), Pg. 34, 2000.

oral-mouse LD50  1500 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Farmakologiya i Toksikologiya Vol. 28, Pg. 230, 1965.

intraperitoneal-mouse LD50  573 mg/kg
Yakugaku Zasshi. Journal of Pharmacy. Vol. 94, Pg. 1419, 1974.

Dermal Toxicity:
skin-rat LD50 > 5000 mg/kg
Toksikologicheskii Vestnik. Vol. (3), Pg. 34, 2000.

Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: control of microorganisms and as slimicides
Recommendation for sodium dimethyl dithiocarbamate usage levels up to:
 not for fragrance use.
 
Recommendation for sodium dimethyl dithiocarbamate flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
Chemical Carcinogenesis Research Information System: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA Substance Registry Services (TSCA): 128-04-1
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 560256
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 3
 sodium N,N-dimethylcarbamodithioate
Chemidplus: 0000128041
EPA/NOAA CAMEO: hazardous materials
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References:
 sodium N,N-dimethylcarbamodithioate
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 128-04-1
Pubchem (cid): 560256
Pubchem (sid): 134974403
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS): View
FDA Indirect Additives used in Food Contact Substances:View
CHEMBL: View
HMDB (The Human Metabolome Database): Search
FooDB: FDB018136
Export Tariff Code: 2930.20.9050
FDA Listing of Food Additive Status: View
ChemSpider: View
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
 carbamic acid, dimethyldithio- sodium salt (8CI)
 carbamodithioic acid, dimethyl-, sodium salt
 carbamodithioic acid, N,N-dimethyl-, sodium salt (1:1)
 dimethyl dithiocarbamate sodium salt
 dimethylcarbamodithioic acid sodium salt
 dimethylcarbamodithioic acid, sodium salt
 dimethyldithiocarbamate sodium salt
N,N-dimethyldithiocarbamate sodium salt
 dimethyldithiocarbamate, sodium salt
 dimethyldithiocarbamic acid sodium salt
 dimethyldithiocarbamic acid, sodium salt
N,N-dimethyldithiocarbamic acid, sodium salt
 sodium dimethylaminecarbodithioate
 sodium dimethylaminocarbodithioate
 sodium dimethylcarbamodithioate
 sodium dimethyldithiocarbamate
 sodium dimethyldithiocarbamates
 sodium N,N-dimethylcarbamodithioate
 sodium N,N-dimethyldithiocarbamate
 sodiumdimethyldithiocarbamate
 sta-fresh 615
 vinditat
 vinstop
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Articles:
PubMed: Development a novel supramolecular solvent microextraction procedure for copper in environmental samples and its determination by microsampling flame atomic absorption spectrometry.
PubMed: Chemical treatment of chelated metal finishing wastes.
PubMed: Ziram causes dopaminergic cell damage by inhibiting E1 ligase of the proteasome.
PubMed: Suppression of the steroid-primed luteinizing hormone surge in the female rat by sodium dimethyldithiocarbamate: relationship to hypothalamic catecholamines and GnRH neuronal activation.
PubMed: Moderating influence of the drinking water disinfection by-product dibromoacetic acid on a dithiocarbamate-induced suppression of the luteinizing hormone surge in female rats.
PubMed: Effectiveness of commercial reagents for heavy metal removal from water with new insights for future chelate designs.
PubMed: Application of process chemistry and SAR modelling to the evaluation of health findings of lower olefins.
PubMed: Blockade of ovulation in the rat by systemic and ovarian intrabursal administration of the fungicide sodium dimethyldithiocarbamate.
PubMed: Effects of some chelating agents on the uptake and distribution of 54Mn(II) in the brown trout (Salmo trutta).
PubMed: Spectrophotometric determination of some dithiocarbamates.
PubMed: Effect of thiram and dithiocarbamate pesticides on the gastrointestinal absorption and distribution of nickel in mice.
PubMed: Effects of some chelating agents on the uptake and distribution of 203Hg2+ in the brown trout (Salmo trutta): studies on ethyl- and isopropylxanthate, diethyl- and diisopropyldithiophosphate, dimethyl- and diethyldithiocarbamate and pyridinethione.
PubMed: Comparative effects of ten dithiocarbamate and thiuram compounds on tissue distribution and excretion of lead in rats.
PubMed: Effects of diethyldithiocarbamate and structural analogs in mice with systemic candidal infections.
PubMed: Effect of dithiocarbamates on citric acid production by Aspergillus niger.
PubMed: Dithiocarbamate-induced redistribution and increased brain uptake of lead in rats.
PubMed: Effect of dithiocarbamates on cellulase activity in culture filtrates of Trichoderma reesei.
PubMed: Laboratory studies of disinfectants against Legionella pneumophila.
PubMed: The influence of dopamine-beta-hydroxylase inhibitors on avoidance reaction in rat.
PubMed: On the conversion of sodium dimethyldithiocarbamate into its alpha-aminobutyric acid derivative by microorganisms.
PubMed: On the transformation of the fungicide sodium dimethyl-dithiocarbamate into its alanine derivative by plant tissues.
PubMed: Investigations on organic fungicides. XI. The role of metals and chelating agents in the fungitoxic action of sodium dimethyldithiocarbamate.
PubMed: The role of metals in the fungitoxic action of sodium dimethyldithiocarbamate.
PubMed: Investigations on organic fungicides. X. Pyruvic acid accumulation and its relation to the phenomenon of inversion growth as effected by sodium dimethyldithiocarbamate.
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