vitamin A acetate
acetic acid, retinyl ester
 
Notes:
Dietary supplement, permitted in infant formulas
  • American International Chemical, LLC.
    • American International Chemical, Inc.
      Consistent sources
      North American supplier for globally sourced ingredients.
      AIC is a Westborough, MA based ISO Certified sales and marketing company serving the food, pharmaceutical, nutritional, personal care, biotech, and industrial markets of North America since 1972. Our success is a result of a company culture built on customer needs, along with partnerships with global manufacturers committed to the rigors and demands of the North American market. Our team of Sales Representatives, along with our network of strategically located warehouses are ready to supply product when and where you need it.
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      Product(s):
      VAAPI1 Vitamin A Acetate
       
  • BOC Sciences
    • BOC Sciences
      Best of Chemicals Supplier
      Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
      BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services.
      BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies.
      Email: Marketing
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      US Email: Sales
      Voice: 1-631-485-4226
      Fax: 1-631-614-7828
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      Product(s):
      127-47-9 VITAMIN A ACETATE >98%
       
  • Charkit Chemical
    • Charkit Chemical Corporation
      The Specialty Chemical Specialists
      Explore this website to discover the products and services that Charkit provides for your industry and please contact us directly to find out how we can be of service to you.
      about: Since 1982, Charkit has been committed to expanding the markets we serve as our roster of products and services continues to grow with us. Our substantial portfolio of personal care ingredients now include a wide array of luxury and exotic components to compliment the key products we have always offered. We have expanded our offerings to the nutraceutical, industrial, and resin markets with a growing roster of versatile and unique ingredients. We continue to lead the way in our traditional markets such as Metal and Water Treatment, Imaging, Flavor & Fragrance, Aroma and Food. Our Pharmaceutical offerings continue to expand, still anchored by the Boronic Derivatives that meet the demands of Suzuki coupling reactions. Please contact us to learn how we can help you reach your goals.
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      Product(s):
      VITAMIN A ACETATE 500
       
  • Glentham Life Sciences
  • Jiangyin Healthway
    • Jiangyin Healthway International Trade Co., Ltd
      Independent Ingredients Supplier
      We provide custom synthesis and contract manufacturing from milligrams to metric tonnes.
      Jiangyin Healthway International Trade Co., Ltd is a professional company, main engaged in manufacturing and exporting aroma chemicals ,food additives , cosmetic ingredient ,pharmaceutical intermediates & other fine chemicals; especially on aroma chemicals , as the major manufacturer of heterocyclic and sulphur aroma compounds , we are the leading independent ingredients supplier to the flavour and fragrance industries in China, can offer hundreds of different high quality aroma chemicals.
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      Product(s):
      130956 Vitamin A Acetate
       
  • Penta International
    • Penta International Corporation
      Chemistry innovation
      At Penta, our products and services help businesses do business better.
      For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes.
      US Email: Technical Services
      US Email: Sales
      US Voice: (973) 740-2300
      US Fax: (973) 740-1839
      Product(s):
      22-86950 VITAMIN A ACETATE
       
  • Zanos
    • Zanos Ltd.
      Distributor of Speciality Chemicals and Natural Ingredients
      Sourcing and supplying quality aroma chemicals and prestige natural ingredients for the flavour and fragrance industry.
      The flavour and fragrance industry's premier source for aroma chemicals and essential oils
      Zanos Ltd. is a B2B supplier of aroma chemicals, speciality chemicals, natural ingredients and vitamins to a diverse range of customers. In Autumn 2020, Stort Chemicals Limited completed their acquisition of Zanos Ltd. Combining our strengths, Stort and Zanos have boosted our respective portfolios of aroma chemicals, speciality chemicals and natural ingredients. With warehousing facilities across the UK, Rotterdam and Hamburg, Zanos is perfectly positioned to dispatch product throughout Europe.
      Email: Contact Zanos
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      Product(s):
      Vitamin A 325.000 I.U./g CWS-A
      Vitamin A 325.000 I.U./g SD CWS-S
      Vitamin A 500.000 I.U./g SD CWS-A
       
Synonyms   Articles   Notes   Search
CAS Number: 127-47-9Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg: 204-844-2
FDA UNII: 3LE3D9D6OY
Nikkaji Web: J34.628D
Beilstein Number: 1915439
MDL: MFCD00019413
XlogP3: 6.30 (est)
Molecular Weight: 328.49544000
Formula: C22 H32 O2
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome or firefox)
Category: nutrient supplements
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
 FDA/DG SANTE Petitions, Reviews, Notices:
184.1930 Vitamin A acetate View - review
FDA Mainterm (SATF):127-47-9 ; VITAMIN A ACETATE
FDA Regulation:
FDA PART 184 -- DIRECT FOOD SUBSTANCES AFFIRMED AS GENERALLY RECOGNIZED AS SAFE
Subpart B--Listing of Specific Substances Affirmed as GRAS
Sec. 184.1930 Vitamin A.
Synonyms   Articles   Notes   Search   Top
Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Soluble in:
 water, 0.0003555 mg/L @ 25 °C (est)
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: skin conditioning
Synonyms   Articles   Notes   Search   Top
Suppliers:
AIDP
Vitamin A Palmitate Retinol 250,000 IU/g
American International Chemical, LLC.
Vitamin A Acetate
BASF
Dry Vitamin A Acetate
BOC Sciences
For experimental / research use only.
VITAMIN A ACETATE >98%
Charkit Chemical
VITAMIN A ACETATE 500
Farbest-Tallman Foods
ZMC Vitamin A Acetate 325,000 IU/gm CWS Gelatin-Free
Flavor: bland
This product is used fortifying powdered products such as infant formulas, dietetic foods and dairy products.
Farbest-Tallman Foods
ZMC Vitamin A Acetate 500,000 IU/gm TAB
Flavor: bland
It is used as a Vitamin A source for dietary supplements including tablet and hard-shell capsule preparations.
Glentham Life Sciences
Vitamin A acetate
Indis NV
For experimental / research use only.
Vitamin A Acetate
Jiangyin Healthway
Vitamin A Acetate
New functional food ingredients
Maypro Industries
Vitamin A Acetate
Penta International
VITAMIN A ACETATE
Qingdao Dacon Trading
Vitamin A Acetate
Santa Cruz Biotechnology
For experimental / research use only.
Retinyl acetate
Sigma-Aldrich: Sigma
For experimental / research use only.
Retinyl acetate synthetic, crystalline solid or supercooled liquid
Zanos
Vitamin A 325.000 I.U./g CWS-A
Zanos
Vitamin A 325.000 I.U./g SD CWS-S
Zanos
Vitamin A 500.000 I.U./g SD CWS-A
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Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-mouse LD50  4100 mg/kg
Journal of the American Academy of Dermatology. Vol. 6, Pg. 652, 1982.

intravenous-mouse LD50  432 mg/kg
United States Patent Document. Vol. #3878202

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: nutrient supplements
Recommendation for vitamin A acetate usage levels up to:
 not for fragrance use.
 
Recommendation for vitamin A acetate flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
ClinicalTrials.gov: search
Daily Med: search
Chemical Carcinogenesis Research Information System: Search
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
Carcinogenic Potency Database: Search
EPA GENetic TOXicology: Search
EPA Substance Registry Services (TSCA): 127-47-9
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 638034
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 2
 [(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenyl] acetate
Chemidplus: 0000127479
RTECS: VH6825000 for cas# 127-47-9
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References:
 [(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenyl] acetate
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 127-47-9
Pubchem (cid): 638034
Pubchem (sid): 134974060
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS): View
CHEBI: View
CHEMBL: View
KEGG (GenomeNet): D01621
HMDB (The Human Metabolome Database): HMDB35185
FooDB: FDB013829
FDA Listing of Food Additive Status: View
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
Synonyms   Articles   Notes   Search   Top
Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
 acetic acid, retinyl ester
(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-yl acetate
(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-enyl)nona-2,4,6,8-tetr aenyl acetate
[(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenyl] acetate
all-trans-retinol acetate
 retinyl acetate
all-trans-retinyl acetate
all-trans-retinylacetate
 vitamin A acetate
all-trans-vitamin A acetate
Synonyms   Articles   Notes   Search   Top
Articles:
PubMed: Determination of vitamins A and E in infant formula and adult/pediatric nutritional formula by HPLC with UV and fluorescence detection: First Action 2012.09.
PubMed: Triple-fortified rice containing vitamin A reduced marginal vitamin A deficiency and increased vitamin A liver stores in school-aged Thai children.
PubMed: Simultaneous determination of 13-cis and all-trans vitamin A palmitate (retinyl palmitate), vitamin A acetate (retinyl acetate), and total vitamin E (alpha-tocopherol and DL-alpha-tocopherol acetate) in infant formula and adult nutritionals by normal phase HPLC: first action 2012.10.
PubMed: [Effects of vitamin A supplementation on nutritional status of iron in healthy adults].
PubMed: β-Carotene in Golden Rice is as good as β-carotene in oil at providing vitamin A to children.
PubMed: Safety evaluation of vitamin A in growing dogs.
PubMed: Cloning, expression and characterization of a lipase gene from the Candida antarctica ZJB09193 and its application in biosynthesis of vitamin A esters.
PubMed: The effect of food preparation on the bioavailability of carotenoids from carrots using intrinsic labelling.
PubMed: UVA photoirradiation of anhydroretinol--formation of singlet oxygen and superoxide.
PubMed: Vitamin A equivalence of spirulina beta-carotene in Chinese adults as assessed by using a stable-isotope reference method.
PubMed: beta-Cryptoxanthin from supplements or carotenoid-enhanced maize maintains liver vitamin A in Mongolian gerbils ( Meriones unguiculatus) better than or equal to beta-carotene supplements.
PubMed: [Vitamin A equivalence of spinach beta-carotene in human body].
PubMed: Use of metabolic stimulators and inhibitors for enhanced production of beta-carotene and lycopene by Blakeslea trispora NRRL 2895 and 2896.
PubMed: Diets rich in polyphenols and vitamin A inhibit the development of type I autoimmune diabetes in nonobese diabetic mice.
PubMed: Interactions of human serum albumin with retinoic acid, retinal and retinyl acetate.
PubMed: Photodecomposition and phototoxicity of natural retinoids.
PubMed: Spinach or carrots can supply significant amounts of vitamin A as assessed by feeding with intrinsically deuterated vegetables.
PubMed: Photoreaction, phototoxicity, and photocarcinogenicity of retinoids.
PubMed: Photodecomposition of retinyl palmitate in ethanol by UVA light-formation of photodecomposition products, reactive oxygen species, and lipid peroxides.
PubMed: Use of the deuterated-retinol-dilution technique to monitor the vitamin A status of Nicaraguan schoolchildren 1 y after initiation of the Nicaraguan national program of sugar fortification with vitamin A.
PubMed: Rapid determination by reversed-phase high-performance liquid chromatography of Vitamins A and E in infant formulas.
PubMed: Mechanisms of TCDD-induced abnormalities and embryo lethality in white leghorn chickens.
PubMed: Teratogenic effects of chronic ingestion of high levels of vitamin A in cats.
PubMed: [Evaluation on intestinal and whole-body conversion of beta-carotene to vitamin A in Chinese adults using a stable isotope reference method].
PubMed: Simultaneous determination of vitamin A and beta-carotene in dietary supplements by liquid chromatography.
PubMed: Determination of liposoluble vitamins in cooked meals, milk and milk products by liquid chromatography.
PubMed: Alpha- and beta-carotene from a commercial puree are more bioavailable to humans than from boiled-mashed carrots, as determined using an extrinsic stable isotope reference method.
PubMed: Bioavailability and antioxidant activity of some food supplements in men and women using the D-Roms test as a marker of oxidative stress.
PubMed: A novel extrinsic reference method for assessing the vitamin A value of plant foods.
PubMed: Influence of vitamin A status on the regulation of uridine (5'-)diphosphate-glucuronosyltransferase (UGT) 1A1 and UGT1A6 expression by L-triiodothyronine.
PubMed: On-line supercritical fluid extraction/enzymatic hydrolysis of vitamin a esters: a new simplified approach for the determination of vitamins a and e in food.
PubMed: A fortifier comprising protein, vitamins, and calcium-glycerophosphate for preterm human milk.
PubMed: Bioavailability trials of beta-carotene from fresh and dehydrated drumstick leaves (Moringa oleifera) in a rat model.
PubMed: Dietary vitamin A modulates the concentrations of RRR-alpha-tocopherol in plasma lipoproteins from calves fed milk replacer.
PubMed: Estimation of the dietary vitamin A requirement of juvenile grass shrimp, Penaeus monodon.
PubMed: Antimutagenic effects and possible mechanisms of action of vitamins and related compounds against genotoxic heterocyclic amines from cooked food.
PubMed: Bioavailability of carotenoids in human subjects.
PubMed: Effect of reduced body weight gain on the evaluation of chemopreventive agents in the methylnitrosourea-induced mammary cancer model.
PubMed: Effect of vitamin A on the oxidative stability of broiler meat during storage: lack of interactions with vitamin E.
PubMed: Binding of retinoids to beta-lactoglobulin isolated by bioselective adsorption.
PubMed: Suppressive effects of retinoids, carotenoids and antioxidant vitamins on heterocyclic amine-induced umu C gene expression in Salmonella typhimurium (TA 1535/pSK 1002).
PubMed: Interactions in indices of vitamin A, zinc and copper status when these nutrients are fed to rats at adequate and increased levels.
PubMed: Effect of retinyl acetate, ascorbic acid and tocopherol supplementation of the feed on egg vitamin A content in Japanese quail.
PubMed: Pigment cholelithiasis induced by vitamin A and its prevention by butylated hydroxytoluene.
PubMed: Strain variation in vitamin A (retinol) status of streptozotocin-induced diabetic rats.
PubMed: Consumption of excess vitamin A, but not excess beta-carotene, causes accumulation of retinol that exceeds the binding capacity of cellular retinol-binding protein, type II in rat intestine.
PubMed: The effect of excessive dietary vitamin A on performance and vitamin E status in swine fed diets varying in dietary vitamin E.
PubMed: Haemorrhagic toxicity of a large dose of alpha-, beta-, gamma- and delta-tocopherols, ubiquinone, beta-carotene, retinol acetate and L-ascorbic acid in the rat.
PubMed: Glucuronidation of all-trans-retinoic acid in liposomal membranes.
PubMed: The influence of dietary levels of vitamin A and fat on colon cancer.
PubMed: Effects of dietary retinyl acetate on the promotion of hepatic enzyme-altered foci by polybrominated biphenyls in initiated rats.
PubMed: Modification of retinyl acetate toxicity in rats by coadministration of menhaden oil.
PubMed: Relationship of vitamin A and vitamin E intake to fasting plasma retinol, retinol-binding protein, retinyl esters, carotene, alpha-tocopherol, and cholesterol among elderly people and young adults: increased plasma retinyl esters among vitamin A-supplement users.
PubMed: Retinyl acetate inhibits estrogen-induced mammary carcinogenesis in female ACI rats.
PubMed: Effects of simultaneous treatment with various chemicals on BHA-induced development of rat forestomach hyperplasia--complete inhibition by diethylmaleate in a 5-week feeding study.
PubMed: Zinc-vitamin A interaction in pregnant and fetal rats: supplemental vitamin A does not prevent zinc-deficiency-induced teratogenesis.
PubMed: Effect of moderate vitamin A supplementation and lack of dietary vitamin A on the development of mammary tumors in female rats treated with low carcinogenic dose levels of 7,12-dimethylbenz(a)anthracene.
PubMed: Effects of vitamin A on cyclophosphamide mutagenicity in vitro (Ames test) and in vivo (mouse micronucleus test).
PubMed: Fat and vitamin A stability in the presence of Ronoxan A and other antioxidants.
PubMed: Localization of tritiated vitamin A in lymph nodes of the mouse: an autoradiographic study of vitamin A-storing cells.
PubMed: Vitamin A - application technology.
PubMed: Hypervitaminosis A combined with calcium deficiency in rats.
PubMed: Studies on urinary arylsulphatase activity in vitamin A deficient rats.
PubMed: Influence of excess vitamin E on vitamin A toxicity in rats.
PubMed: Polarography of conjugated unsaturated lipids.
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