polysorbate 21
polyoxyethylene (21) sorbitan monolaurate
 
Notes:
sorbitan mono-9-octadecanoate poly(oxy-1,2-ethanediyl) derivatives; complex mixtures of polyoxyethylene ethers used as emulsifiers or dispersing agents in pharmaceuticals.
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CAS Number: 9005-64-5 
Other(deleted CASRN): 118955-39-8
ECHA EC Number: 500-018-3
MDL: MFCD00165986
Category: emulsifiers, surfactants
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
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Google Scholar: with word "odor"Search
Google Patents: Search
US Patents: Search
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PubMed: Search
NCBI: Search
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Physical Properties:
Food Chemicals Codex Listed: No
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: surfactants
surfactant - emulsifying
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Suppliers:
Kao Corporation
RHEODOL TW-L106
Odor: characteristic
Use: Emulsifier for pharmaceuticals and cosmetics, Stabilizer for color materials, Stabilizer for emulsion polymerizations, Emulsifier for adjuvant of agrochemicals, Emulsifier for water based metal process cutting oils.
Sigma-Aldrich
For experimental / research use only.
TWEEN® 21
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-hamster LD50  18 mL/kg
Food Research. Vol. 21, Pg. 348, 1956.

intraperitoneal-mouse LD50  2640 mg/kg
Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 1581, 1976.

intravenous-mouse LD50  1420 mg/kg
Research Progress in Organic-Biological and Medicinal Chemistry. Vol. 2, Pg. 316, 1970.

oral-mouse LD50  > 33000 mg/kg
Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 1581, 1976.

intraperitoneal-rat LD50  3850 mg/kg
Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 1581, 1976.

intravenous-rat LD50  770 mg/kg
Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 1581, 1976.

oral-rat LD50  36700 uL/kg
Food Research. Vol. 21, Pg. 348, 1956.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: emulsifiers, surfactants
Recommendation for polysorbate 21 usage levels up to:
 not for fragrance use.
 
Recommendation for polysorbate 21 flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
Daily Med: search
Chemical Carcinogenesis Research Information System: Search
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA Substance Registry Services (TSCA): 9005-64-5
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 1
Chemidplus: 0009005645
RTECS: TR7400000 for cas# 9005-64-5
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References:
Canada Domestic Sub. List: 9005-64-5
Pubchem (sid): 135288054
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Other Information:
HMDB (The Human Metabolome Database): Search
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
 hetsorb l-4
 peg-21 sorbitan laurate
 peg-21 sorbitan monolaurate
 polyethylene glycol (21) sorbitan laurate
 polyoxyethylene (21) sorbitan laurate
 polyoxyethylene (21) sorbitan monolaurate
 rheodol TW-L106
 tween 21
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