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Category: preservatives
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| | FDA/DG SANTE Petitions, Reviews, Notices: |
| 184.1751 | Sodium citrate View - review |
| EU SANCO | Sodium citrates View - review |
| JECFA Food Additive: | Trisodium Citrate |
| GSFA Codex: | Trisodium citrate (331(iii)) |
| FDA Mainterm (SATF): | 68-04-2 ; TRISODIUM CITRATE |
| FDA Regulation: | FDA PART 131 -- MILK AND CREAM Subpart B--Requirements for Specific Standardized Milk and Cream Sec. 131.111 Acidified milk.
FDA PART 131 -- MILK AND CREAM Subpart B--Requirements for Specific Standardized Milk and Cream Sec. 131.112 Cultured milk.
FDA PART 131 -- MILK AND CREAM Subpart B--Requirements for Specific Standardized Milk and Cream Sec. 131.160 Sour cream.
FDA PART 131 -- MILK AND CREAM
FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS Subpart B--Requirements for Specific Standardized Cheese and Related Products Sec. 133.169 Pasteurized process cheese.
FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS Subpart B--Requirements for Specific Standardized Cheese and Related Products Sec. 133.173 Pasteurized process cheese food.
FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS Subpart B--Requirements for Specific Standardized Cheese and Related Products Sec. 133.179 Pasteurized process cheese spread.
FDA PART 150 -- FRUIT BUTTERS, JELLIES, PRESERVES, AND RELATED PRODUCTS Subpart B--Requirements for Specific Standardized Fruit Butters, Jellies, Preserves, and Related Products Sec. 150.141 Artificially sweetened fruit jelly.
FDA PART 150 -- FRUIT BUTTERS, JELLIES, PRESERVES, AND RELATED PRODUCTS Subpart B--Requirements for Specific Standardized Fruit Butters, Jellies, Preserves, and Related Products Sec. 150.161 Artificially sweetened fruit preserves and jams.
FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS Subpart C--Substances for Use as Components of Coatings Sec. 175.300 Resinous and polymeric coatings.
FDA PART 179 -- IRRADIATION IN THE PRODUCTION, PROCESSING AND HANDLING OF FOOD Subpart C--Packaging Materials for Irradiated Foods Sec. 179.45 Packaging materials for use during the irradiation of prepackaged foods.
FDA PART 181 -- PRIOR-SANCTIONED FOOD INGREDIENTS Subpart B--Specific Prior-Sanctioned Food Ingredients Sec. 181.29 Stabilizers.
FDA PART 184 -- DIRECT FOOD SUBSTANCES AFFIRMED AS GENERALLY RECOGNIZED AS SAFE Subpart B--Listing of Specific Substances Affirmed as GRAS Sec. 184.1751 Sodium citrate.
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Physical Properties:
| Appearance: | white crystalline powder (est) |
| Assay: | 99.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| logP (o/w): | -0.280 (est) |
| Soluble in: |
| | water, 1.2e+005 mg/L @ 25 °C (est) | | | water, 4.34E+05 mg/L @ C (exp) |
| Insoluble in: |
| | alcohol |
Organoleptic Properties:
| Odor Strength: | none |
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Odor Description: at 100.00 %. | odorless |
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
| ADM |
| Sodium Citrate Anhydrous Powder
Odor: odorless Use: Sodium Citrate Anhydrous is derived from citric acid and is available in either free-flowing colorless granular, fine granular or powder forms. It is odorless and freely soluble in water, but insoluble in alcohol. Storage at room temperature in tightly sealed containers is recommended. Sodium citrate dihydrate is the most broadly used emulsifying salt in sliced processed cheese products. It is commonly used as a buffering agent in combination with citric acid to provide precise pH control required in many food and beverage applications. In meat products it is used as an anticoagulant of fresh livestock blood and as a curing accelerator. The detergent-building and rapid biodegradability characteristics of sodium citrate enable its use as an environmentally acceptable phosphate substitute in a large variety of household cleaning products. |
| ADM |
| Sodium Citrate Anhydrous, USP/FCC
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| Atlantic Chemicals |
| Trisodium Citrate
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| BOC Sciences |
| For experimental / research use only. |
| Sodium citrate,anhydrous 99%
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| Glentham Life Sciences |
| Sodium citrate, anhydrous
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| Graham Chemical |
| Sodium Citrate
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| Jungbunzlauer Suisse |
| Trisodium Citrate Anhydrous
Flavor: characteristic Trisodium citrate is a tribasic salt of citric acid. It is produced by complete neutralisation of citric acid with high purity sodium hydroxide or carbonate and subsequent crystallisation and dehydration.
The common hydrate form, trisodium citrate dihydrate, is widely used in foods, beverages and various technical applications mainly as buffering, sequestering or emulsifying agent, whereas the anhydrous form finds its uses in particular applications such as water sensitive dry blends and instant beverages, surfactants, fragrances as well as in tablets and OTC products.
Jungbunzlauer trisodium citrate anhydrous is manufactured from trisodium citrate dihydrate. Water molecules of the dihydrate crystals are removed by a patented process without destroying the original crystal matrix. The resulting crystals have a porous matrix that can be used as a carrier for inorganic and/or organic substances, especially after being impregnated with liquids. Further, due to the absence of water, the product is not prone to caking. Trisodium citrate anhydrous is also used in applications where excess water is not desired. |
| Lluch Essence |
| SODIUM CITRATE NATURAL
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| M&U International |
| Sodium Citrate, Kosher
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| Penta International |
| SODIUM CITRATE ANHYDROUS GRANULAR USP - FCC
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| Penta International |
| SODIUM CITRATE ANHYDROUS POWDER USP - FCC
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| Penta International |
| TRISODIUM CITRATE
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| Sigma-Aldrich |
| For experimental / research use only. |
| Citric acid trisodium salt ≥98% (GC), anhydrous
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| Tianjin Talent Chemical |
| Trisodium Citrate
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Safety Information:
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
intraperitoneal-rat LD50 1548 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
LUNGS, THORAX, OR RESPIRATION: CYANOSIS
GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS Journal of Pharmacology and Experimental Therapeutics. Vol. 94, Pg. 65, 1948.
intravenous-rabbit LD50 449 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
LUNGS, THORAX, OR RESPIRATION: CYANOSIS
GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS Journal of Pharmacology and Experimental Therapeutics. Vol. 94, Pg. 65, 1948.
intravenous-mouse LD50 170 mg/kg LUNGS, THORAX, OR RESPIRATION: CYANOSIS
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS Journal of Pharmacology and Experimental Therapeutics. Vol. 94, Pg. 65, 1948.
intraperitoneal-mouse LD50 1364 mg/kg LUNGS, THORAX, OR RESPIRATION: CYANOSIS
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS Journal of Pharmacology and Experimental Therapeutics. Vol. 94, Pg. 65, 1948.
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | preservatives |
| Recommendation for sodium citrate anhydrous usage levels up to: | | | not for fragrance use.
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| Recommendation for sodium citrate anhydrous flavor usage levels up to: |
| | not for flavor use.
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Safety References:
| EPI System: | View |
| ClinicalTrials.gov: | search |
| NIOSH International Chemical Safety Cards: | search |
| Chemical Carcinogenesis Research Information System: | Search |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA Substance Registry Services (TSCA): | 68-04-2 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 6224 |
| National Institute of Allergy and Infectious Diseases: | Data |
| | trisodium 2-hydroxypropane-1,2,3-tricarboxylate |
| Chemidplus: | 0000068042 |
| RTECS: | 68-04-2 |
References:
| | trisodium 2-hydroxypropane-1,2,3-tricarboxylate |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 68-04-2 |
| Pubchem (cid): | 6224 |
| Pubchem (sid): | 134971042 |
Other Information:
Potential Blenders and core components note
Potential Uses:
| | buffering agents | |
| | chelating agents | |
Occurrence (nature, food, other): note
Synonyms:
| | citric acid trisodium salt | | 2- | hydroxy-1,2,3-propane tricarboxylic acid trisodium salt anhydrous | | | natrocitral | | | trisodium 2-hydroxy-1,2,3-propane tricarboxylate | | | trisodium 2-hydroxypropane-1,2,3-tricarboxylate | | | trisodium citrate |
Articles:
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