| CAS Number: | 39421-75-5 |
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| Other(deleted CASRN): | 114680-41-0 |
| ECHA EC Number: | 609-675-1 |
| FDA UNII: | 3A1I7376TC |
| Formula: | C3 H8 O2.x-Unspecified |
| CAS Number: | 68442-94-4 |
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| ECHA EC Number: | 270-497-9 |
| Formula: | unspecified |
Category: cosmetic agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
Organoleptic Properties:
| Odor Strength: | none |
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Odor Description: at 100.00 %. | odorless |
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | cosmetic agents |
| Recommendation for hydroxypropyl guar gum usage levels up to: | | | not for fragrance use.
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| Recommendation for hydroxypropyl guar gum flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
| FDA Indirect Additives used in Food Contact Substances: | View |
| HMDB (The Human Metabolome Database): | Search |
| Wikipedia: | View |
Potential Blenders and core components note
Potential Uses:
| | antistatic agents | |
| | binding agents | |
| | emulsion stabilisers | |
| | film formers | |
| | viscosity controlling agents | |
Occurrence (nature, food, other): note
Synonyms:
| | guar gum 2-hydroxypropyl ether | | | guar gum, 2-hydroxypropyl ether | | | guaraprolose | | | hydroxypropyl guar | | | N-hance HP series hydroxypropyl guar |
Articles:
| PubMed: | Stretching properties of xanthan and hydroxypropyl guar in aqueous solutions and in cosmetic emulsions. |
| PubMed: | Tuning cellulose nanocrystal gelation with polysaccharides and surfactants. |
| PubMed: | Performance of a new thermostable mannanase in breaking guar-based fracturing fluids at high temperatures with little premature degradation. |
| PubMed: | Efficacy and safety of chondroitin sulfate/xanthan gum versus polyethylene glycol/propylene glycol/hydroxypropyl guar in patients with dry eye. |
| PubMed: | Homogeneous synthesis of hydroxypropyl guar gum in an ionic liquid 1-butyl-3-methylimidazolium chloride. |
| PubMed: | Stretching properties of xanthan, carob, modified guar and celluloses in cosmetic emulsions. |
| PubMed: | Preparation and in vitro characterization of mucoadhesive hydroxypropyl guar microspheres containing amlodipine besylate for nasal administration. |
| PubMed: | Lubricant with gelling agent in treating dry eye in adult Chinese patients. |
| PubMed: | Modification of hydroxypropyl guar gum with ethanolamine. |
| PubMed: | Prospective, randomized, controlled comparison of SYSTANE UD eye drops versus VISINE INTENSIV 1% EDO eye drops for the treatment of moderate dry eye. |
| PubMed: | Evaluation of guar gum derivatives as gelling agents for microbial culture media. |
| PubMed: | Characterization of the interaction between hydroxypropyl guar galactomannan and galectin-3. |
| PubMed: | Systane lubricant eye drops in the management of ocular dryness. |
| PubMed: | Charge regulation enables anionic hydroxypropyl guar-borate adsorption onto anionic and cationic polystyrene latex. |
| PubMed: | The impact of artificial tears containing hydroxypropyl guar on mucous layer. |
| PubMed: | Novel hydroxypropyl-guar gellable lubricant eye drops for treatment of dry eye. |
| PubMed: | Cationic liposome colloidal stability in the presence of guar derivatives suggests depletion interactions may be operative in artificial tears. |
| PubMed: | Efficacy in patients with dry eye after treatment with a new lubricant eye drop formulation. |
| PubMed: | Novel ocular lubricant containing an intelligent delivery system: details of its mechanism of action. |
| PubMed: | The effect of preservative-free HP-Guar on dry eye after phacoemulsification: a flow cytometric study. |
| PubMed: | Comparison of the clinical effects of carbomer-based lipid-containing gel and hydroxypropyl-guar gel artificial tear formulations in patients with dry eye syndrome: a 4-week, prospective, open-label, randomized, parallel-group, noninferiority study. |
| PubMed: | The effect of lubricating eye drop containing hydroxypropyl guar on perimetry results of patients with glaucoma and trachomatous dry eye. |
| PubMed: | Not all anionic polyelectrolytes complex with DTAB. |
| PubMed: | Protecting the ocular surface and improving the quality of life of dry eye patients: a study of the efficacy of an HP-guar containing ocular lubricant in a population of dry eye patients. |
| PubMed: | Reversible flocculation with hydroxypropyl guar-borate, a labile anionic polyelectrolyte. |
| PubMed: | Impact on ocular surface evaporation of an artificial tear solution containing hydroxypropyl guar. |
| PubMed: | Extensional properties of hydroxypropyl ether guar gum solutions. |
| PubMed: | TEMPO-mediated selective oxidation of substituted polysaccharides--an efficient approach for the determination of the degree of substitution at C-6. |
| PubMed: | Hydroxypropyl-guar gellable lubricant eye drops for dry eye treatment. |
| PubMed: | [Toxicity of a new moistening agent and preservative in vitro]. |
| PubMed: | Derivatization of guar to sodium carboxy methyl hydroxy propyl derivative; characterization and evaluation. |
| PubMed: | An evaluation of tear film breakup time extension and ocular protection index scores among three marketed lubricant eye drops. |
| PubMed: | Manipulating formation and drug-release behavior of new sol-gel silica matrix by hydroxypropyl guar gum. |
| PubMed: | Study of hydroxy propyl guar derivative for its gelling property and it's use in the formulation of tenoxicam gels. |
| PubMed: | Differential tissue-on-tissue lubrication by ophthalmic formulations. |
| PubMed: | New semi-interpenetrating network hydrogels: synthesis, characterization and properties. |
| PubMed: | A clinical evaluation of Systane. |
| PubMed: | Hydroxypropyl guar-borate interactions with tear film mucin and lysozyme. |
| PubMed: | A clinical comparison of two different prednisolone acetate formulations in patients undergoing cataract surgery. |
| PubMed: | An open-label evaluation of HP-Guar gellable lubricant eye drops for the improvement of dry eye signs and symptoms in a moderate dry eye adult population. |
| PubMed: | Pre-clinical investigation of the efficacy of an artificial tear solution containing hydroxypropyl-guar as a gelling agent. |
| PubMed: | Clinical evaluation of an HP-guar gellable lubricant eye drop for the relief of dryness of the eye. |
| PubMed: | Characterization and intermolecular interactions of hydroxypropyl guar solutions. |
| PubMed: | [Investigation of the carboxymethyl hydroxypropyl guar gum cross-linked with metal ions]. |
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