Articles:
hydantoin, 1,3-bis(hydroxymethyl)-5,5-dimethyl-
Notes:
None found
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| CAS Number: | 6440-58-0 |  3D/inchi
|
| ECHA EINECS - REACH Pre-Reg: | 229-222-8 | |
| FDA UNII: | BYR0546TOW | |
| Nikkaji Web: | J207.046D | |
| Beilstein Number: | 0882348 | |
| XlogP3-AA: | -0.20 (est) | |
| Molecular Weight: | 188.18344000 | |
| Formula: | C7 H12 N2 O4 | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: preservatives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
| FDA Mainterm (IAUFC): | 6440-58-0 ; 1,3-BIS(HYDROXYMETHYL)-5,5-DIMETHYLHYDANTOIN |
Physical Properties:
| Assay: | 95.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Boiling Point: | 303.71 °C. @ 760.00 mm Hg (est) |
| Flash Point: | 279.00 °F. TCC ( 137.50 °C. ) (est) |
| logP (o/w): | -1.078 (est) |
| Soluble in: | |
| water, 2.612e+005 mg/L @ 25 °C (est) | |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| CosIng: | cosmetic data |
| Cosmetic Uses: |
preservatives |
Suppliers:
| Acme-Hardesty |
| DMDM Hydantoin
Odor: characteristic Use: Antimicrobial Preservative Used in Personal Care Applications. |
| BOC Sciences |
| For experimental / research use only. |
| 1,3-bis(hydroxymethyl)-5,5-dimethylimidazolidine-2,4-dione 98% |
| Connect Chemicals |
| Dimethyl Dimethylhydantoin (DMDMH) |
| Kingyoung Bio Technical |
| DMDM Hydantoin |
| Kraft Chemical |
| DMDM Hydantoin |
| Nanjing Jiancheng Chemical |
| DMDM hydantoin (DMDMH)
Odor: characteristic Use: DMDMH is widely used as antiseptic for its bactericidal effect. It can constrain the bacterium, yeast, mould, gram-positive bacterium and gram-negative bacterium. It can be applied in all kinds of cosmetics and Personal Care, such as shampoo, conditioner, cream, shower gel and so on. |
| Shiva Chemicals and Pharmaceuticals |
| Dimethyloldimethyl Hydantoin |
Safety Information:
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
|
intraperitoneal-mouse LDLo 1320 mg/kg Agricultural and Biological Chemistry. Vol. 40, Pg. 1705, 1976. oral-mouse LDLo 3000 mg/kg Agricultural and Biological Chemistry. Vol. 40, Pg. 1705, 1976. oral-rat LD50 2000 mg/kg LIVER: OTHER CHANGES GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH KIDNEY, URETER, AND BLADDER: OTHER CHANGES Journal of the American College of Toxicology. Vol. 7(3), Pg. 245, 1988. | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | preservatives | ||
| Recommendation for DMDM hydantoin usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for DMDM hydantoin flavor usage levels up to: | |||
| not for flavor use. | |||
Safety References:
| EPI System: | View |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA Substance Registry Services (TSCA): | 6440-58-0 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 22947 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 1 |
| 1,3-bis(hydroxymethyl)-5,5-dimethylimidazolidine-2,4-dione | |
| Chemidplus: | 0006440580 |
References:
| 1,3-bis(hydroxymethyl)-5,5-dimethylimidazolidine-2,4-dione | |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 6440-58-0 |
| Pubchem (cid): | 22947 |
| Pubchem (sid): | 134987962 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| FDA Indirect Additives used in Food Contact Substances: | View |
| HMDB (The Human Metabolome Database): | Search |
| FooDB: | FDB004274 |
| ChemSpider: | View |
| Wikipedia: | View |
| Formulations/Preparations: •dantogard active ingredient 32.0% dmdm hydantoin, 7.5% mdm hydantoin •dantogard plus industrial preservative active ingredient 4.5% 3-iodo-2-propynyl butylcarbamate, 87.0% dmdm hydantoin, 0.4% mdm hydantoin •dantogard xl-1000 95.5% dmdm hydantoin, 4.0% mdm hydantoin •dantogard ii preservative active ingredient 26.4% dmdm hydantoin, 23.2% mdm hydantoin •dantocil ig active ingredient 0.04% 5-chloro-2-methyl-3(2h)-isothiazolone, 0.01% 2-methyl-3(2h)-isothiazolone, 29.4% dmdm hydantoin, 27.9% mdm hydantoin •glycoserve active ingredient 45.0% dmdm hydantoin, 10.0% mdm hydantoin •troy 2063 active ingredient 8.0% 1,2-benzisothiazolin-3-one, 9.6% dmdm hydantoin, 2.2% mdm hydantoin •troysan 680 active ingredient 10.9% 1,2-benzisothiazolin-3-one, 12.5% dmdm hydantoin, 2.9% mdm hydantoin | |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| preservatives |
Occurrence (nature, food, other): note
| not found in nature |
Synonyms:
| dantoin-DMDMH | |
| 1,3- | di(hydroxymethyl)-5,5-dimethylhydantoin |
| 1,3- | dihydroxymethyl-5,5-dimethylhydantoin |
| 1,3- | dimethylol-5,5-dimethyl hydantoin |
| 1,3- | dimethylol-5,5-dimethyl-hydantoin |
| 1,3- | dimethylol-5,5-dimethylhydantion |
| dimethylol-5,5-dimethylhydantoin | |
| 1,3- | dimethylol-5,5-dimethylhydantoin |
| dimethyloldimethyl hydantoin | |
| dimethyloldimethylhydantoin | |
| DMDMH | |
| glycoserve-DMDMH | |
| hydantoin | |
| hydantoin, 1,3-bis(hydroxymethyl)-5,5-dimethyl- | |
| 1,3-bis( | hydroxymethyl)-5,5-dimethyl-1,3-diazolidine-2,4-dione |
| 1,3-bis( | hydroxymethyl)-5,5-dimethyl-2,4-imidazolidinedione |
| 1,3-bis( | hydroxymethyl)-5,5-dimethylimidazolidine-2,4-dione |
| 2,4- | imidazolidinedione, 1,3-bis(hydroxymethyl)-5,5-dimethyl- |
| mackstat DM |