Articles:
| None found yet. Try the PubMed Search. |
Notes:
a group of glucose polymers made by certain bacteria. dextrans are used therapeutically as plasma volume expanders and anticoagulants. they are also commonly used in biological experimentation and in industry for a wide variety of purposes. Indirect food additive produced by bacterial fermentation of sucrose
Dextran is a complex, branched glucan (polysaccharide made of many glucose molecules) composed of chains of varying lengths (from 10 to 150 kilodaltons). It is used medicinally as an antithrombotic (anti-platelet), to reduce blood viscosity, and as a volume expander in anemia.
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Glentham Life Sciences Ltd The Chemical, Biochemical & Research Essentials Supplier Glentham Life Sciences is a supplier of fine chemicals and raw materials with warehousing, laboratories and packaging facilities in the UK. With a Glentham Life Sciences account you can view more product details, request quotes and order products online. Email: Info Email: Sales Email: Tech Support Voice: +44 (0) 1225 667798 Fax: +44 (0) 2033 978909 Facebook Twitter Linkedin Google+ News Distribution Products List: View Product(s): GE1910 Dextran 1,000 GE2215 Dextran 40,000 GE4231 Dextran 70,000
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| CAS Number: | 9004-54-0 |  3D/inchi
|
| ECHA EINECS - REACH Pre-Reg: | 232-677-5 | |
| FDA UNII: | EW7Q6SVD0D | |
| XlogP3-AA: | -7.20 (est) | |
| Molecular Weight: | 504.44024000 | |
| Formula: | C18 H32 O16 | |
| BioActivity Summary: | listing | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: food-contact surface of paper and paperboard
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
| FDA/DG SANTE Petitions, Reviews, Notices: | |
| 186.1275 | Dextrans View - review |
| 186.1275 | Dextran View - review |
| FDA Mainterm (SATF): | 9004-54-0 ; DEXTRANS (AVG M W LESS THAN 100,000) |
| FDA Regulation: | |
| FDA PART 186 -- INDIRECT FOOD SUBSTANCES AFFIRMED AS GENERALLY RECOGNIZED AS SAFE Subpart B--Listing of Specific Substances Affirmed as GRAS Sec. 186.1275 Dextrans. | |
Physical Properties:
| Food Chemicals Codex Listed: | No |
| Boiling Point: | 952.80 °C. @ 760.00 mm Hg (est) |
| Flash Point: | 622.00 °F. TCC ( 327.70 °C. ) (est) |
| logP (o/w): | -4.259 (est) |
| Soluble in: | |
| water, 1e+006 mg/L @ 25 °C (est) | |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| CosIng: | cosmetic data |
| Cosmetic Uses: |
binding agents viscosity controlling agents |
Suppliers:
| BOC Sciences |
| For experimental / research use only. |
| Dextran 110 - MW: 100,000 to 120,000 |
| Glentham Life Sciences |
| Dextran 1,000 |
| Glentham Life Sciences |
| Dextran 40,000 |
| Glentham Life Sciences |
| Dextran 70,000 |
Safety Information:
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
|
unreported-mammal (species unspecified) LD50 13500 mg/kg BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Gematologiya i Transfuziologiya. Hematology and Transfusion Science. Vol. 31(10), Pg. 38, 1986. intravenous-mouse LD50 12100 mg/kg Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 1023, 1972. oral-mouse LD50 > 12000 mg/kg Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 1023, 1972. intravenous-rabbit LD50 17400 mg/kg BEHAVIORAL: ATAXIA BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 1023, 1972. intravenous-rabbit LD50 208000 mg/kg LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) LUNGS, THORAX, OR RESPIRATION: CYANOSIS Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 3, Pg. 201, 1975. intravenous-rat LD50 6900 mg/kg Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 1023, 1972. oral-rat LD50 > 3000 mg/kg Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 1023, 1972. | |
| Dermal Toxicity: | |
|
subcutaneous-mouse LD50 13900 mg/kg Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 1023, 1972. subcutaneous-rat LD50 10700 mg/kg Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 1023, 1972. | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | food-contact surface of paper and paperboard | ||
| Recommendation for dextrans usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for dextrans flavor usage levels up to: | |||
| not for flavor use. | |||
Safety References:
| EPI System: | View |
| ClinicalTrials.gov: | search |
| Daily Med: | search |
| Chemical Carcinogenesis Research Information System: | Search |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| Carcinogenic Potency Database: | Search |
| EPA Substance Registry Services (TSCA): | 9004-54-0 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 4125253 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 2 |
| 2,3,4,5-tetrahydroxy-6-[3,4,5-trihydroxy-6-[[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxyhexanal | |
| Chemidplus: | 0009004540 |
References:
| 2,3,4,5-tetrahydroxy-6-[3,4,5-trihydroxy-6-[[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxyhexanal | |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 9004-54-0 |
| Pubchem (cid): | 4125253 |
| Pubchem (sid): | 135289239 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| FDA Substances Added to Food (formerly EAFUS): | View |
| FDA Indirect Additives used in Food Contact Substances: | View |
| KEGG (GenomeNet): | C00372 |
| HMDB (The Human Metabolome Database): | Search |
| FooDB: | FDB012591 |
| MedlinePlusSupp: | View |
| ChemSpider: | View |
| Wikipedia: | View |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| binding agents | ||
| viscosity controlling agents |
Occurrence (nature, food, other): note
| not found in nature |
Synonyms:
| dextran 4 | |
| dextran 8 | |
| 2,3,4,5- | tetrahydroxy-6-[3,4,5-trihydroxy-6-[[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxyhexanal |