| PubMed: | Over-expression of Catharanthus roseus tryptophan decarboxylase and strictosidine synthase in rol gene integrated transgenic cell suspensions of Vinca minor. |
| PubMed: | Regulation of vincamine biosynthesis and associated growth promoting effects through abiotic elicitation, cyclooxygenase inhibition, and precursor feeding of bioreactor grown Vinca minor hairy roots. |
| PubMed: | Synthesis of 15-methylene-eburnamonine from (+)-vincamine, evaluation of anticancer activity, and investigation of mechanism of action by quantitative NMR. |
| PubMed: | Studies on the interaction between vincamine and human serum albumin: a spectroscopic approach. |
| PubMed: | Transcranial Doppler assessment of cerebral vasomotor reactivity in evaluating the effects of vinpocetine in cerebral small vessel disease: a pilot study. |
| PubMed: | Vinpocetine attenuates lipid accumulation and atherosclerosis formation. |
| PubMed: | Mechanochemical activation of vincamine mediated by linear polymers: assessment of some "critical" steps. |
| PubMed: | Brain targeted solid lipid nanoparticles for brain ischemia: preparation and in vitro characterization. |
| PubMed: | Rationale of using Vinca minor Linne dry extract phytocomplex as a vincamine's oral bioavailability enhancer. |
| PubMed: | Drug salt formation via mechanochemistry: the case study of vincamine. |
| PubMed: | Vinpocetine suppresses pathological vascular remodeling by inhibiting vascular smooth muscle cell proliferation and migration. |
| PubMed: | Mechanochemically induced disordered structures of vincamine: the different mediation of two cross-linked polymers. |
| PubMed: | DNA binding studies of Vinca alkaloids: experimental and computational evidence. |
| PubMed: | The vincamine derivative vindeburnol provides benefit in a mouse model of multiple sclerosis: effects on the Locus coeruleus. |
| PubMed: | Phytochemical Investigation of Vinca minor Cultivated in Iran. |
| PubMed: | [Tissue culture of Vinca minor and determination of vincamine]. |
| PubMed: | Deviation from van't Hoff dependence in RP-LC induced by tautomeric interconversion observed for four compounds. |
| PubMed: | Cytotoxicity, antiviral and antimicrobial activities of alkaloids, flavonoids, and phenolic acids. |
| PubMed: | Vincamine-producing endophytic fungus isolated from Vinca minor. |
| PubMed: | Aggressive behavior during social interaction in mice is controlled by the modulation of tyrosine hydroxylase expression in the prefrontal cortex. |
| PubMed: | Separation of vinca alkaloid enantiomers by capillary electrophoresis applying cyclodextrin derivatives and characterization of cyclodextrin complexes by nuclear magnetic resonance spectroscopy. |
| PubMed: | Antinociceptive effect of vinpocetine--a comprehensive survey. |
| PubMed: | Alpneumines A-H, new anti-melanogenic indole alkaloids from Alstonia pneumatophora. |
| PubMed: | Vinpocetine inhibits NF-kappaB-dependent inflammation via an IKK-dependent but PDE-independent mechanism. |
| PubMed: | WITHDRAWN: Interventions for normal tension glaucoma. |
| PubMed: | Brain trace element concentration of rats treated with the plant alkaloid, vincamine. |
| PubMed: | Neuroprotective effects of vinpocetine and its major metabolite cis-apovincaminic acid on NMDA-induced neurotoxicity in a rat entorhinal cortex lesion model. |
| PubMed: | Seco-tabersonine alkaloids from Tabernaemontana corymbosa. |
| PubMed: | Development and validation of an adsorptive stripping voltammetric method for the quantification of vincamine in its formulations and human serum using a Nujol-based carbon paste electrode. |
| PubMed: | Effects of Vinpocetine on mitochondrial function and neuroprotection in primary cortical neurons. |
| PubMed: | Simultaneous determination of piracetam and vincamine by spectrophotometric and high-performance liquid chromatographic methods. |
| PubMed: | Smart stability-indicating spectrophotometric methods for determination of binary mixtures without prior separation. |
| PubMed: | Mitigation of nociception via transganglionic degenerative atrophy: possible mechanism of vinpocetine-induced blockade of retrograde axoplasmic transport. |
| PubMed: | In vitro anticholinesterase activity of various alkaloids. |
| PubMed: | Application of unsymmetrical indirect covariance NMR methods to the computation of the (13)C <--> (15)N HSQC-IMPEACH and (13)C <--> (15)N HMBC-IMPEACH correlation spectra. |
| PubMed: | Synthesis of (+/-)-3H-epivincamine via a Rh(II)-triggered cyclization/cycloaddition cascade. |
| PubMed: | Effect of vinpocetine on retrograde axoplasmic transport. |
| PubMed: | Syntheses of vinca alkaloids and related compounds. 104. A concise synthesis of (-)-vincapusine. |
| PubMed: | Development and application of an automated solution stability assay for drug discovery. |
| PubMed: | Eburnamine derivatives and the brain. |
| PubMed: | Measurement and pharmacokinetics of vincamine in rat blood and brain using microdialysis. |
| PubMed: | Catalytic N-sulfonyliminium ion-mediated cyclizations to alpha-vinyl-substituted isoquinolines and beta-carbolines and applications in metathesis. |
| PubMed: | Stability-indicating methods for determination of vincamine in presence of its degradation product. |
| PubMed: | [11C]vinpocetine: a prospective peripheral benzodiazepine receptor ligand for primate PET studies. |
| PubMed: | [Neuroprotection strategies: effect of vinpocetine in vitro oxidative stress models]. |
| PubMed: | Enhanced tail pinch-induced activation of catecholamine metabolism in the pericerulean area of RU 24722-treated rats. |
| PubMed: | Interventions for normal tension glaucoma. |
| PubMed: | Lipophilicity of vinpocetine and related compounds characterized by reversed-phase thin-layer chromatography. |
| PubMed: | Vinpocetine is a potent blocker of rat NaV1.8 tetrodotoxin-resistant sodium channels. |
| PubMed: | [Investigation of vasoactive agents with indole skeletons at Richter Ltd]. |
| PubMed: | [Open-angle glaucoma clinical presentation and management]. |
| PubMed: | Chiral HPLC separation and CD spectra of the enantiomers of the alkaloid tacamonine and related compounds. |
| PubMed: | Separation of the four pairs of enantiomers of vincamine alkaloids by enantioselective high-performance liquid chromatography. |
| PubMed: | Cerebroprotective drugs shorten the hypoxia-induced onset of electrical silence in unanesthetized rats. |
| PubMed: | Capillary electrophoresis separation of vinpocetine and related compounds: prediction of electrophoretic mobilities in partly aqueous media. |
| PubMed: | Singular subsets of locus coeruleus neurons may recover tyrosine hydroxylase phenotype transiently expressed during development. |
| PubMed: | In vitro-in vivo correlation and comparative bioavailablity of vincamine in prolonged-release preparations. |
| PubMed: | In situ examination of tyrosine hydroxylase activity in the rat locus coeruleus using (3',5')-[(3)H(2)]-alpha-fluoromethyl-tyrosine as substrate of the enzyme. |
| PubMed: | Proton speciation and microspeciation of vinpocetine and related compounds in aqueous and biomimetic media. |
| PubMed: | [Comparison of the effect of vincamine and nicergoline in the treatment of ischemic stroke]. |
| PubMed: | Effects of oral brovincamine on visual field damage in patients with normal-tension glaucoma with low-normal intraocular pressure. |
| PubMed: | [Effects of brovincamine fumarate on choroidal blood volume in rabbits]. |
| PubMed: | Plasticity of tyrosine hydroxylase gene expression within BALB/C and C57Black/6 mouse locus coeruleus. |
| PubMed: | [A new approach to the treatment of patients with circulatory encephalopathy]. |
| PubMed: | Controlled targeting of tyrosine hydroxylase protein toward processes of locus coeruleus neurons during postnatal development. |
| PubMed: | Positive cooperativity of acetylcholine and other agonists with allosteric ligands on muscarinic acetylcholine receptors. |
| PubMed: | Synthesis of vinca alkaloids and related compounds. Part 84. Sulfonamide derivatives of some vinca alkaloids with cardiovascular activity. |
| PubMed: | Vincamine and vincanol are potent blockers of voltage-gated Na+ channels. |
| PubMed: | Pharmacological modulations of adrenergic phenotype in medullary C2 and C3 cell groups of adult rat. |
| PubMed: | Positive allosteric action of eburnamonine on cardiac muscarinic acetylcholine receptors. |
| PubMed: | Tyrosine hydroxylase expression within Balb/C and C57black/6 mouse locus coeruleus. I. Topological organization and phenotypic plasticity of the enzyme-containing cell population. |
| PubMed: | Ion-molecule reactions of oxygenated chemical ionization reagents with vincamine. |
| PubMed: | [Blood flow changes in the optic nerve head of albino rabbits following intravenous administration of brovincamine fumarate, an improver of cerebral circulation and metabolism]. |
| PubMed: | Prevention of visual field defect progression with brovincamine in eyes with normal-tension glaucoma. |
| PubMed: | Therapeutic efficacy of vincamine in dementia. |
| PubMed: | Therapeutic approaches for memory impairments. |
| PubMed: | Phenotypic characteristics of expressed tyrosine hydroxylase protein in the adult rat nucleus tractus solitarius: plasticity revealed by RU24722 treatment. |
| PubMed: | RU24722 induces spatially organized phenotypic plasticity in the locus coeruleus. |
| PubMed: | Calcium antagonistic vasodilator mechanisms of brovincamine fumarate studied in canine cerebral artery. |
| PubMed: | [Experimental study of radiation protective efficacy of Vinca alkaloid drugs]. |
| PubMed: | Long-term effect of RU24722 on tyrosine hydroxylase in the rat locus coeruleus: differential effects of two enantiomeric forms. |
| PubMed: | Further characterization of the long-term effect of RU24722 on tyrosine hydroxylase in the rat locus coeruleus. |
| PubMed: | Protective action of vinpocetine against experimentally induced gastric damage in rats. |
| PubMed: | [Drug-induced ventricular tachycardia]. |
| PubMed: | Synthesis and pharmacological evaluation of (nitrooxy)alkyl apovincaminates. |
| PubMed: | Decrease in the reactivity of locus coeruleus neurons to hypotension after an increase in their tyrosine hydroxylase content: a subregional in vivo voltammetry study in the rat. |
| PubMed: | Somatotopic organization of tyrosine hydroxylase expression in the rat locus coeruleus: long term effect of RU24722. |
| PubMed: | Evaluation of the hepatotoxicological effects of a drug in an in vivo/in vitro model. |
| PubMed: | Determination of vincamine in human plasma by high-performance liquid chromatography with ultraviolet detection. |
| PubMed: | Effect of brovincamine on cerebral circulation and metabolism in internal carotid artery occlusion examined by positron emission tomography. |
| PubMed: | Inhibitory action of brovincamine on catecholamine secretion from cultured bovine adrenal medullary cells: possible relation to its blocking action on Ca2+ channels. |
| PubMed: | Effects of several cerebroprotective drugs on NMDA channel function: evaluation using Xenopus oocytes and [3H]MK-801 binding. |
| PubMed: | Effects of vinburnine on experimental models of learning and memory impairments. |
| PubMed: | Ontogeny of tyrosine hydroxylase concentration in locus coeruleus of newborn rats: long-term effects of RU24722. |
| PubMed: | The pharmacotherapy of focal cortical ischaemia in the mouse. |
| PubMed: | Pharmacokinetic aspects of the sublingual administration of vincamine. |
| PubMed: | Drug test value by transcranial Doppler in the diagnosis of neurologic vascular diseases. |
| PubMed: | Effects of aging and vincamine derivatives on pericapillary microenvironment: stereological characterization of the cerebral capillary network. |
| PubMed: | 3,4-Dihydroxyphenylacetic acid (DOPAC) as an index of noradrenaline turnover: effects of Hydergine and vincamine. |
| PubMed: | [Comparison of antagonistic effects of several drugs on calcium current in a giant neuron of an African snail (Achatina fulica Férussac)]. |
| PubMed: | The families of cognition enhancers. |
| PubMed: | Flunarizine. A reappraisal of its pharmacological properties and therapeutic use in neurological disorders. |
| PubMed: | [The effect of modification of excipients for the bioavailability of vinburnine]. |
| PubMed: | Effects of brovincamine on stereological capillary parameters in adult and old Fischer-344 rats. |
| PubMed: | Muscarinic receptor-mediated regulation of OM-853-enhanced dopamine release in striatum of rat. |
| PubMed: | Trachealis responses induced by vincamine and vinpocetine; inhibition by indomethacin and Ca2+ dependence. |
| PubMed: | Effect of (+/-)-methyl 3-ethyl-2,3,3a,4-tetrahydro-1H-indolo-[3,2,1-de] [1,5] naphthyridine-6-carboxylate hydrochloride (OM-853), a new vincamine analogue, on the metabolism and function of cerebral serotonergic neurons. |
| PubMed: | RU 24722, a new eburnamine derivative, induces selective alterations in cerebral glucose utilization in freely moving rat. |
| PubMed: | [The oral liquid form of vinburnine: biopharmaceutics]. |
| PubMed: | Double tracer autoradiographic method for sequential evaluation of regional cerebral perfusion. |
| PubMed: | Filterability of human erythrocytes--drug induced prevention of aging in vitro. |
| PubMed: | Long-term effects of RU24722 on tyrosine hydroxylase of the rat brain. |
| PubMed: | Effect of various classes of drugs on complete ischemia induced by decapitation and cyanide intoxication in mice. |
| PubMed: | Use of alveolar macrophages in antianoxic drug studies. |
| PubMed: | Effect of vasodilators on hepatic microcirculation: a study of the inhibition of norepinephrine-induced vasoconstriction in the isolated perfused rat liver. |
| PubMed: | [Measurement of brain tyrosine hydroxylase concentrations by quantitative autoradiography after transfer of soluble proteins to nitro-cellulose]. |
| PubMed: | [Effect of brovincamine fumarate on cerebral ischemia acutely induced by BLCL in SHRSR]. |
| PubMed: | Flow-cytometric studies with eleutherococcus senticosus extract as an immunomodulatory agent. |
| PubMed: | Cerebroprotective effect of nicergoline and interference with the anti-hypoxic effect of prostacyclin. |
| PubMed: | Protective effects of vinpocetine and structurally related drugs on the lethal consequences of hypoxia in mice. |
| PubMed: | Effects of brovincamine on the stereological parameters of corticocerebral capillaries. |
| PubMed: | Octahydropyrazino[2',3':3,4]pyrido[1,2-a]indoles. A new class of potent antihypertensive agents. |
| PubMed: | Vinpocetine enhances retrieval of a step-through passive avoidance response in rats. |
| PubMed: | Neocortical rhythmic slow activity during wakefulness and paradoxical sleep in rats. |
| PubMed: | A comparison of some of the pharmacological properties of the new eburnamenine derivative vindeburnol with those of vincamine, vinburnine, dihydroergotoxine mesilate and nicergoline. |
| PubMed: | Disposition kinetics and oral bioavailability of vincamine-loaded polyalkyl cyanoacrylate nanoparticles. |
| PubMed: | [Effects of three cerebral vasodilators--nimodipine, nifedipine and vincamine on chemically-induced amnesia in rodents]. |
| PubMed: | [Nimodipine, nifedipine and vincamine improve amnesia induced by anisodine and sodium nitrite in rats and mice]. |
| PubMed: | [Low molecular weight dextrans (Rheomacrodex) in the therapy of inner ear hearing loss]. |
| PubMed: | [Effects of Ginkgo biloba extract on a cerebral ischemia model in gerbils]. |
| PubMed: | Determination of vincamine in plasma by high-performance liquid chromatography with voltammetric detection. |
| PubMed: | [Evaluation of the activity of vindeburnol by spectral analysis of human EEG]. |
| PubMed: | Vinpocetine: nootropic effects on scopolamine-induced and hypoxia-induced retrieval deficits of a step-through passive avoidance response in rats. |
| PubMed: | [Synthesis of octahydroindolo [2,3-a] quinolizine derivatives]. |
| PubMed: | [Vincamine in cerebrovascular insufficiency. Occupational medicine approaches in cerebral diseases]. |
| PubMed: | Capillary gas chromatographic determination of vincamine in plasma. |
| PubMed: | [Effects of vincamine and a vincamine-papaverine combination on erythrocyte flexibility in diabetic patients]. |
| PubMed: | [Effects of a vincamine-papaverine combination on platelet aggregation in geriatric patients with glucose and/or lipid metabolism disorders]. |
| PubMed: | [Influence of nitrogenous fertilizer on the growth of Vinca minor]. |
| PubMed: | The metabolic fate of 11-bromo[15-3H]vincamine in man. |
| PubMed: | Experimental cerebral infarction in Mongolian gerbils: effects of vincamine on lesion size, survival and behavior. |
| PubMed: | Pharmacokinetics and metabolism of vincamine and related compounds. |
| PubMed: | Biopharmaceutic and pharmacokinetic aspects of vincamine HCl. |
| PubMed: | Cardiovascular effects of brovincamine and possible mechanisms involved. |
| PubMed: | [Biopharmaceutics of vincamine salts after oral administration in humans]. |
| PubMed: | [Agents to improve cerebrovascular circulation and cerebral metabolism--brovincamine]. |
| PubMed: | [How the production of an alkaloid leads to tissue culture of higher plants. Assay of vincamine production]. |
| PubMed: | Effects of the new eburnamenine derivative RU 24722 on EEG recovery and cerebral energy metabolism after complete ischemia. |
| PubMed: | In vivo effect of RU 24722 and drugs used for the treatment on senile cerebral insufficiency on rat brain ornithine decarboxylase. |
| PubMed: | Alteration of enzymes in ageing human fibroblasts in culture. III. Modification of superoxide dismutase as an environmental and reversible process. |
| PubMed: | Dose-response relationship of vindeburnol based on spectral analysis of posturographic recordings. |
| PubMed: | Memory dysfunction and vigilance: neurophysiological and psychopharmacological aspects. |
| PubMed: | Locus coeruleus as a target for psychogeriatric agents. |
| PubMed: | Effect of a new eburnamine derivative, RU 24722, on the turnover of monoamines in mouse brain: selective and reversible decrease of noradrenaline. |
| PubMed: | [Application of spectrum analysis of equilibration recordings (posturography) in clinical pharmacology of vindeburnol]. |
| PubMed: | Role of drugs in recovery of metabolic function of rat brain following severe hypoglycemia. |
| PubMed: | Classification and determination of pharmacodynamics of a new antihypoxidotic drug, vinconate, by pharmaco-EEG and psychometry. |
| PubMed: | [Biologic availability of vincamine from tablets with a hydrophilic matrix. II]. |
| PubMed: | The effects of vincamine on experimental cerebral infarction in Mongolian gerbils: a pilot study. |
| PubMed: | [Comparative study of the in vitro availability of vincamine from delayed-release forms. 1]. |
| PubMed: | Effects of brovincamine on the autonomic nervous function in the dog and rat. |
| PubMed: | Cerebral and cerebellar metabolic changes induced by drugs during the recovery period after profound hypoglycemia. |
| PubMed: | Calcium antagonistic action involved in vasodilation by brovincamine. |
| PubMed: | Preparation and in vivo studies of a new drug delivery system. Nanoparticles of alkylcyanoacrylate. |
| PubMed: | Evaluation of the effect of vincamine teprosilate on behavioural performances of patients affected with chronic cerebrovascular disease. |
| PubMed: | Acute i.v. vincamine teprosilate administration: quantified investigation in elderly subjects. |
| PubMed: | Pharmaco-EEG study on vincamine and on teproside in patients with chronic cerebrovascular disease. |
| PubMed: | Pharmacokinetic study of vincamine teprosilate. |
| PubMed: | Vincamine TPS activity on glycoconjugate metabolism of the brain: effect on lysosomal enzymes. |
| PubMed: | Cerebral antioedematous effect of Teproside and of some vincamine derivatives. |
| PubMed: | The effects of bromvincamine and vincamine on regional cerebral blood flow and mental functions in patients with multi-infarct dementia. |
| PubMed: | Potentiation of the anticonvulsant effects of antiepileptic drugs by "nootropics"; a potential new therapeutic approach. |
| PubMed: | Effects induced by vincamine teprosilate on chronic cerebrovascular disease: preliminary results. |
| PubMed: | Effect of ischaemia and pharmacological treatment on enzyme activities of cortical mitochondria and synaptosomes. |
| PubMed: | [Determination of vincamine in Vinca minor]. |
| PubMed: | Determination of vincamine by high-performance liquid chromatography with dual-wavelength ultraviolet detection. |
| PubMed: | Study on the anti-hypoxic effect of some drugs used in the pharmacotherapy of cerebrovascular disease. |
| PubMed: | Pharmacokinetic study of two pharmaceutical preparations containing alkaloid vincamine administered orally to human subjects. |
| PubMed: | The effect of some drugs with purported antianoxic effect on veratridine-induced purine release from isolated rat hypothalamic synaptosomes. |
| PubMed: | [Synthesis of 1-ethyl-1,2,3,4,6,7-hexahydroindolo-[2,3a]-quinolizinium perchlorate, a key intermediate of vincamine]. |
| PubMed: | 'Cerebroactive' drugs. Clinical pharmacology and therapeutic role in cerebrovascular disorders. |
| PubMed: | Gas chromatographic assay of pramiracetam in human plasma using nitrogen specific detection. |
| PubMed: | Alkaloids from Tabernaemontana psorocarpa. |
| PubMed: | [Evaluation of the anti-platelet aggregation action of oxovinca in the diffuse vascular deterioration syndrome]. |
| PubMed: | Cerebro-circulatory effects of so-called 'vasodilators' in the anaesthetised rat. |
| PubMed: | [Study of 2 antianoxic agents by a method of decreased barometric pressure: demonstration of a different rate of action]. |
| PubMed: | [Treatment of sudden deafness. Apropos of the parenteral and peroral administration of Cerebroxine]. |
| PubMed: | The efficacy of the cerebral metabolic enhancers in the treatment of senile dementia. |
| PubMed: | [Nicergoline and steal effect in favor of zones of hypoperfusion in cerebral ischemic accidents]. |
| PubMed: | The metabolic fate of 11-bromo-[15-3H] vincamine in rats, dogs and humans. |
| PubMed: | [Controlled clinical study on the activity of vincamine-teprosylate in the so-called aging brain syndrome]. |
| PubMed: | Vincamine: a psychogeriatric agent blocking synaptic potentiation in hippocampus. |
| PubMed: | [12-Methoxy-17,18-dehydro-vincamine and 16-epi-isositsirikine, alkaloids from Tabernaemontana psorocarpa]. |
| PubMed: | [Effect of vincamine on blood viscosity]. |
| PubMed: | [Autoradiographic demonstration of the passage of vincamin through the blood-brain barrier]. |
| PubMed: | Determination of 11-bromovincamine in human plasma by high-performance liquid chromatography. |
| PubMed: | [Multi-center study of Cetal retard. Results of 60 studies]. |
| PubMed: | [Clinical and Neuropsychological changes associated with vincamin treatment in cerebrovascular disease (author's transl)]. |
| PubMed: | Changes in mouse hepatocytes caused by vincamin. A thin-sectioning and freeze-fracture study. |
| PubMed: | A new phthalidyl derivative of apovincaminic acid: (3 alpha,16 alpha)-eburnamenine-14 carboxylic acid phthalidyl ester (AF 698). A preliminary report on its chemical and pharmacological properties. |
| PubMed: | The effect of vincamine, hydergine and piracetam on the firing rate of locus coeruleus neurons. |
| PubMed: | Effects of agents used in the pharmacotherapy of cerebrovascular disease on the oxygen consumption of isolated cerebral mitochondria. |
| PubMed: | [Treatment of acoustic traumatism with injectable vincamine. Random double blind clinical trial with a complementary comparative element (author's transl)]. |
| PubMed: | Cerebral vasodilators (second of two parts). |
| PubMed: | [Cerebrovascular insufficiency. Diagnosis, therapy and control of its course]. |
| PubMed: | [Clinical evaluation of treatment with Vincimax in 60 cases of cerebral circulatory insufficiency]. |
| PubMed: | [Assay and bioavailability of vincamine (author's transl)]. |
| PubMed: | Rapid communication the activating activity of vincamine, piracetam, and hydergine on the activity of the noradrenergic neurons of the locus coeruleus. |
| PubMed: | The effect of ischemia and pharmacological treatment evaluated on synaptosomes and purified mitochondria from rat cerebral cortex. |
| PubMed: | [Effect of Bromovincamine on noradrenaline and 5-hydroxytryptamine contents, and glucose metabolism in rat brain: analysis using spontaneously hypertensive rats (SHR) (author's transl)]. |
| PubMed: | Effect of vincamine on some enzymatic activities from various areas of the beagle dog cerebral cortex. |
| PubMed: | [Cerebral ischemic vasculopathy: clinical and thermographic study in patients treated with papaveroline]. |
| PubMed: | [In vitro dissolution test: evaluation criterion for prolonged release dosage forms vincamine example (author's transl)]. |
| PubMed: | [Experimental electropharmacologic studies of cerebral ischemia (author's transl)]. |
| PubMed: | Comparative in vitro evaluation of six commercial vincamine prolonged-release dosage forms. |
| PubMed: | High-performance liquid chromatographic determination of vincamine. |
| PubMed: | [Multi-center clinical study of the effects of a vasoregulatory-eumetabolic drug (vincamine hydrochloride) on the psychological symptoms of cerebrovascular insufficiency]. |
| PubMed: | High-performance liquid chromatography of eburnane alkaloids. I. Separation on reversed phases. |
| PubMed: | Determination of vincamine in human plasma using automated high-performance liquid chromatography. |
| PubMed: | Direct vascular effects of agents used in the pharmacotherapy of cerebrovascular disease on isolated cerebral vessels. |
| PubMed: | [Therapeutic action of a combination of vincamine and piracetam in peripheral labyrinthine syndromes with a vascular component]. |
| PubMed: | [Cardiac toxicity of vincamine: a seven cases report of ventricular arrhythmias by parenteral administration of vincamine (author's transl)]. |
| PubMed: | The effect of Cavinton on cerebrovascular resistance and its use in ophthalmological patients. A double-blind trial. |
| PubMed: | Contact sensitivity to vincamine tartrate. |
| PubMed: | Cerebral blood flow: physiology, pathophysiology and pharmacological effects. |
| PubMed: | [Parieval in 52 cases of internal ear deafness]. |
| PubMed: | Drug interference on some biochemical parameters of rat cerebral cortex during post-ischemic recovery. |
| PubMed: | [Therapeutic use of a new vasoactive drug in cerebral vascular diseases in elderly patients]. |
| PubMed: | [Neuropsychologic evaluation of the action of oxovinca in the syndrome of diffuse deterioration of vascular origin (author's transl)]. |
| PubMed: | [Changes in the condition for the use of Cavinton and Devincan. New regulation concerning the prescription and use of these 2 drugs]. |
| PubMed: | [Pharmacologic modification of the circulation in the brain]. |
| PubMed: | [Successful resuscitation from sudden death caused by Cavinton]. |
| PubMed: | Effects of vincamine on EEG sleep patterns in man: a pilot study. |
| PubMed: | Age-associated changes in deoxyglucose uptake in whole brain. |
| PubMed: | The effect of an acute infusion of vincamine and ethyl apovincaminate on cerebral blood flow in healthy volunteers. |
| PubMed: | [Medical treatment of acute disorders of cerebral circulation]. |
| PubMed: | Cerebral regulation-cerebral regulators. |
| PubMed: | Metabolism of vincamine in the rat in vivo and in vitro. |
| PubMed: | [The use of the Mongolian gerbil as a model for cerebrovascular involvement]. |
| PubMed: | [Severe ventricular arrhythmia following parenteral administration of vincamine. Predisposing factors in 6 cases]. |
| PubMed: | Age-dependent modification of drug interference on the enzymatic activities of the rat brain. |
| PubMed: | [Double-blind controlled study of the effects of vincamine hydrochloride on some parameters of cardiovascular function in aged bronchopneumopathic patients]. |
| PubMed: | [Cerebroxine and the treatment of sudden deafness. Apropos of 2 representative cases]. |
| PubMed: | [Vincapront Retard in geriatrics. Results of a multicenter study on patients with organic psychoses]. |
| PubMed: | [Pathopharmacologic models of cerebral disorders]. |
| PubMed: | [Use of the anti-hypoxia agent vincamine in disorders of the blood supply in the eye]. |
| PubMed: | [Treatment of acoustic trauma with Cetal retard]. |
| PubMed: | [Drug therapy in cerebral disorders. A double-blind study with Cetal retard in aged subjects]. |
| PubMed: | [Efficacy of Cetal retard in cerebral insufficiency in general practice]. |
| PubMed: | [Evaluation of Cetal in patients with acute confusion]. |
| PubMed: | [Proof of the efficacy of parenteral Cetal in psychopathologic conditions after brain concussion]. |
| PubMed: | [Measurement of regional brain circulation by means of xenon 133 inhalation]. |
| PubMed: | [Controlled testing of vincamine with special reference to the flow properties of blood]. |
| PubMed: | [Therapy with cerebral anti-hypoxidotics]. |
| PubMed: | [Therapeutic influence of vincamine on impairment of cerebral performance in elderly patients. Results of a double-blind study (author's transl)]. |
| PubMed: | [High altitude insomnia. Efficacy of flunitrazepam]. |
| PubMed: | [Quantitative determination of drugs by in situ spectrophotometry of chromatograms for pharmacokinetic studies. I. Sulpiride and other benzamides, vincamine, naftazone (author's transl)]. |
| PubMed: | [The chronic, recurrent, cervical and lumbar vertebrae syndromes. Effect of vincamine depot in patients with chronic, recurrent, cervical and lumbar vertebrae syndromes]. |
| PubMed: | [Experience with the combination of vincamine and papaverine in chronic brain syndrome]. |
| PubMed: | [Vincamine in the therapy of cerebral vascular diseases in the aged]. |
| PubMed: | [Double-blind study of the therapeutic activity of cerebroxine in the treatment of chronic cerebral circulatory insufficiency]. |
| PubMed: | [Vincamine in cerebral arteriosclerosis: therapeutic effects evaluated clinically and by retinal fluoro-angiography]. |
| PubMed: | [Therapy of chronic cerebrovascular arteriosclerotic insufficiency in a geriatric patient]. |
| PubMed: | [Chronic, recurrent, cervical-spine syndrome. Therapeutic observations with vincamin-depot]. |
| PubMed: | Hydergine and vincamine derivative LD 4298 exhibit no anti-sickling properties in vitro. |
| PubMed: | Pharmacokinetics of vinpocetine in humans. |
| PubMed: | Comparative study of the clinical effect of vincamine versus papaverine given parenterally in the acute phase of stroke. |
| PubMed: | [32P-incorporation in adenosine phosphates of the rat brain after oral application of vincamine for 2 weeks (author's transl)]. |
| PubMed: | [Propharmacopoea technical notes]. |
| PubMed: | The effect of a vincamine derivative on vegetative reactions provoked by labyrinth stimulation. |
| PubMed: | [Verapamil and torsade de pointe (author's transl)]. |
| PubMed: | Influence of various vasodilatory drugs on the cerebral circulation in rabbits and rats. |
| PubMed: | Autoradiographic evidence for passage of vincamine through the blood-brain barrier. |
| PubMed: | Electronystagmographic study in rabbits on the vestibular effect of vincamine. |
| PubMed: | Studies on the vincamine-papaverine association. VI. Interference with alpha receptors. Preliminary clinical evidence. |
| PubMed: | Studies on the vincamine-papaverine association. V. Interference with alpha receptors. Experimental study. |
| PubMed: | Cerebral metabolic and hemodynamic activities of l-eburnamonine in the anesthetized dog. A comparison with vincamine. |
| PubMed: | [The effect of vincamine on vigilance disorders in the elderly (author's transl)]. |
| PubMed: | [Controlled clinical study of the effects of Anasclerol in hospitalized patients with cerebrovascular disorders]. |
| PubMed: | [Vincamine N4-mononitrate (author's transl)]. |
| PubMed: | [Interaction of vincamine on various effects of amphetamine at the central level]. |
| PubMed: | [Effect of vincamine on platelet respiration]. |
| PubMed: | [Metabolism of vincamine in the rat]. |
| PubMed: | Severe hypocapnia applied to study the effect of vincamine on cerebral circulation. |
| PubMed: | Influence of vincamine and piracetam on sleep--waking pattern of the cat. |
| PubMed: | [Effects of vincamine on the mesenteric circulation in the rat. Microcirculatory evaluation of the vasodilator activity of vincamine]. |
| PubMed: | [Respiratory effects of vincamine hydrochloride]. |
| PubMed: | [Cardiovascular action of vincamine hydrochloride]. |
| PubMed: | Pharmacological actions on hypoxic increase of rat brain cortex extracellular K+ ion. |
| PubMed: | [Treatment of initial cerebrovascular insufficiency with vincamine. Polycentric research on 828 cases]. |
| PubMed: | [Absorption, distribution and elimination of vincamine hydrochloride in the rat]. |
| PubMed: | [Comparative study of 2 drugs used in the treatment of cerebral vascular insufficiency: I-Eburnamonine and Vincamine]. |
| PubMed: | Circulatory effect of several cerebral circulatory drugs in man, with special reference to aminophylline, papaverine, cyclandelate, vincamine, prostaglandin E1 and isoxsuprine. |
| PubMed: | [Kinetic behavior of 3H-vincamine in man. Compartmental analysis]. |
| PubMed: | [Metabolic study of Vincamine in cranial trauma (author's transl)]. |
| PubMed: | [A case of "torsade de pointe" during vincamine therapy]. |
| PubMed: | Determination of vincamine in plasma by selected ion monitoring. |
| PubMed: | Medical therapy of cerebral ischemia. Vasoactive and eumetabolic therapy. |
| PubMed: | Assessment of pharmacological effects on cerebral blood flow. |
| PubMed: | Cerebral metabolic, hemodynamic and antihypoxic properties of l-eburnamonine. |
| PubMed: | Hydergine and vincamine derivative LD 4298 exhibit no anti-sickling properties in vitro. |
| PubMed: | Studies on the vincamine-papaverine association iii. clinical use in cardiac patients. |
| PubMed: | Studies on the vincamine-papaverine association ii. acute toxicity in experimental animals as a function of the speed of infusion. |
| PubMed: | Studies on the vincamine-papaverine association. i. biochemical investigations. |
| PubMed: | [Interpretation of mean dissolution kinetics in multidimentional analysis. Application to quinidine and vicamine preparations]. |
| PubMed: | [Blood levels of vincamine. Comparative study of vincamine in delayed and immediate actions]. |
| PubMed: | Central effects of vincamine in intact and "encéphale isolé" fowl preparations. |
| PubMed: | Comparative evaluation of peripheral effects of vincamine and serotonin in various in vitro and in vivo preparations. |
| PubMed: | The effect of vincamine on the regional cerebral blood flow in man. |
| PubMed: | [Relative bioavailability of a vincamine retard formulation. Pharmacokinetic study in normal subjects (author's transl)]. |
| PubMed: | [Clinical, psychological and neurophysiological results of double-blind study on vincamine-cromesilate in patients with cerebro-vascular insufficiency (author's transl)]. |
| PubMed: | [Pharmacokinetics of multilayer vincamine dragees. Study of normal subjects]. |
| PubMed: | Comparative study of the clinical effects of vincamine + glycerol versus glycerol + placebo in the acute phase of stroke. |
| PubMed: | [Demonstrating the effectiveness of cerebroactive drugs in aged patients. Results of a randomized double-blind study of a vincamine containing special preparation]. |
| PubMed: | [Effect of L-eburnamonine on bronchial respiratory resistance in the anesthetized guinea pig. Comparison with vincamine]. |
| PubMed: | [Modifications by 1-eburnamonine and vincamine on 2,3-diphosphoglycerate blood levels in the presence or absence of histotoxic hypoxia produced by potassium cyanide in the awake rat]. |
| PubMed: | Studies on the vincamine-papaverine association. IV. Interference with beta-receptors in experimental animals. |
| PubMed: | Gas chromatographic method for the determination of vincamine in blood. |
| PubMed: | [Disparity in the kinetics of vincamine and vincamine hydrochloride absorption in the rat]. |
| PubMed: | [Comparative study of vincamine and rutovincine (LJ 533) on the cerebral hyperemia in rats with chronic hypoxia]. |
| PubMed: | Multi-compartmental modeling and kinetic parameter identification of the systemic distribution of vincamine after oral administration in the rat and in the man. |
| PubMed: | [Effect of vincamine on the fibrocellular smooth muscle]. |
| PubMed: | [Alerting effect of vincamine in rats (author's transl)]. |
| PubMed: | [Effect of vincamine on sleep-wakefulness equilibrium in the cat (author's transl)]. |
| PubMed: | [Comparative pharmacodynamic properties of apolar alkaloids of Vinca minor L. (Apocynaceae) (vincamine, vinca fraction and vinacamine free vinca fraction)]. |
| PubMed: | Hemodynamic profile of a new cerebral vasodilator, vincamine and of one of its derivatives, apovincaminic acid ethylester (RGH-4405). |
| PubMed: | [Cerebral protecting activity of 1-eburnamonine studied on 3 models of acute hypoxic agression. Comparison with vincamine]. |
| PubMed: | [Experimental studies on the effects of vincamine and its analogues on cerebrovascular circulation]. |
| PubMed: | [Application of multicompartimental analysis to the pharmacokinetics of vincamine in man]. |
| PubMed: | [Effect of technologic factors on the release of vincamine incorporated into hydrophilic matrices]. |
| PubMed: | A new enantioselective total synthesis of natural vincamine via an intramolecular Mannich reaction of an silyl enol ether. |
| PubMed: | [Pharmacology of vincamine and its derivatives]. |
| PubMed: | [Effects of vincamine on in vitro cultured nerve tissue of mice embryos]. |
| PubMed: | Influence of hypercapnia on the cerebrovascular activities of some drugs used in the treatment of cerebral ischemia. |
| PubMed: | [The effect of vincamine on cerebral blood flow as a function of application rate (author's transl)]. |
| PubMed: | [On the influence of vincamine on human cerebral blood flow in the acute test. Studies with 133Xe clearance method (author's transl)]. |
| PubMed: | [The influence of vincamine on global and regional cerebral blood flow in acute and subchronic human cerebral ischimia (author's transl)]. |
| PubMed: | [Vincamine concentrations in plasma and cerebrospinal fluid in patients following intravenous infusion (author's transl)]. |
| PubMed: | [Plasma concentrations and renal excretion of vincamine after oral administration in man (author's transl)]. |
| PubMed: | [Cardiac effects of vincamine]. |
| PubMed: | [Fluorescence assay and pharmacokinetics of vincamine in rats (author's transl)]. |
| PubMed: | [Double-blind comparison of vincamine and placebo in patients with presbyacusis (author's transl)]. |
| PubMed: | [On the role of vincamine in the therapy of cerebrovascular diseases and impairment of cerebral function (author's transl)]. |
| PubMed: | Effect of Vincamine on CBF under pharmacokinetic aspects. |
| PubMed: | The cerebral hemodynamic effect of Vincamine. |
| PubMed: | [Study of the antihypoxic effect of eburnamonine in acute and recurrent anoxia on the cerebral electric activity in curarized rats. Comparison with vincamine]. |
| PubMed: | [On the pharmacokinetics of vincamine after i.v. and oral application to the dog (author's transl)]. |
| PubMed: | [Effect of vincamine, vinervine and serotonin on the sexual cycle in rats]. |
| PubMed: | [Effect of vincamine on the re-establishment of wakefulness after fluothane narcosis]. |
| PubMed: | [Specific assessment of the cerebral and cardiac effects of asphyxic hypoxia. Application to the study of substances with protective activity]. |
| PubMed: | In vivo antispasmodic activity of Sulcotidil. |
| PubMed: | [Effects of vincamine treatment on cerebral arteriosclerotic vasculopathy]. |
| PubMed: | The synthesis of ethyl apovincaminate. |
| PubMed: | [A cholinergic participation in the increase of cerebral cortical blood flow induced by vincamine (rat) (author's transl)]. |
| PubMed: | [Pharmacokinetic study of oral vincamine]. |
| PubMed: | [Experimental and clinical studies on various metabolic effects of vincamine]. |
| PubMed: | [Psychoactive effect of vincamine in a group of subjects affected by recurrent depressive syndrome. Preliminary note]. |
| PubMed: | [Gastrokinetic effect of Vincamine]. |
| PubMed: | [Stereoselective synthesis of optically active vincamine]. |
| PubMed: | [Vincamine in patients with cerebral vascular insufficiency]. |
| PubMed: | Indolizines II: search for potential oral hypoglycemic agents. |
| PubMed: | [Vincamine in the treatment of cerebral circulatory insufficiency in old age]. |
| PubMed: | [Indole alkaloids induction of tremors: effect on photosensible epilepsy in Papiopapio]. |
| PubMed: | Letter: A high yield stereospecific total synthesis of vincamine. |
| PubMed: | [Clinical, rheoencephalographic and ophthalmodynamographic double-blind studies of the effects of vincamine in the treatment of cerebrovascular diseases]. |
| PubMed: | [Vincamine in the treatment of minor ictus (due to transient cerebral ischemia)]. |
| PubMed: | [Letter: Syncope due to arrhythmia. Role of vincamine apropos of 3 observations]. |
| PubMed: | [Use of an original protocol in the study of the action of vincamine on cerebral metabolism]. |
| PubMed: | [Vincamine effects on cultured chicken fibroblasts in vitro]. |
| PubMed: | [Changes in cerebral electrogenesis caused by vincamine in the baboon, Papio papio]. |
| PubMed: | [Clinical and electroencephalographic results of a double-blind test with vincamine (Pervincamine) in advanced cerebral sclerosis (author's transl)]. |
| PubMed: | [Use of a cerebral oxygenator drug in chronic encephalopathies (apropos of the trial of vincamine)]. |
| PubMed: | [Effects of vincamine on patients with head injuries. Clinical and laboratorial studies of 50 cases]. |
| PubMed: | Studies on indole alkaloid biosynthesis. VI. The eburnamine-vincamine alkaloids. |
| PubMed: | [Therapeutic trial of vincamine]. |
| PubMed: | Chemical structure and pharmacological properties of synthetic vincamine derivatives. I. Systemic circulatory effects. |
| PubMed: | [Vinca minor L. alkaloids. II. On the decomposition products of vincamine]. |
| PubMed: | [Mechanism of the therapeutic effect of vincamine in disorders of the cerebral circulation]. |
| PubMed: | [Electroencephalographic study of the effect of vincamine on the central nervous systme in rabbits]. |
| PubMed: | The action of vincamine on the isolated trachea. |
| PubMed: | [A micro-method for the determination of vincamine by thin-layer chromatography]. |
| PubMed: | Absolute configuration of vincamine and some other alkaloids of the eburnamonine type. |
| PubMed: | THE ANALYSIS OF THE MODE OF ACTION OF VINCAMINE AND SOME OTHER DIHYDROEBURNAMENINE LIKE COMPOUNDS ON THE ISOLATED INTESTINE. |
| PubMed: | Alterations in renal haemodynamics and urine flow in the dog after administration of vincamine. I. |
| PubMed: | Alterations of renal haemodynamics and urine flow in the dog after administration of vincamine. II. |
| PubMed: | The effect of vincamine on the blood pressure of the rat. |
| PubMed: | [Pharmacology of substances isolated from Vinca minor L. I. Effect of vincamine on arterial blood pressure]. |
| PubMed: | [Various physiological properties of vincamine, a crystallized alkaloid of lesser periwinkle (Vinca minor L.)]. |