Articles:
4-(2-aminoethyl)phenol hydrochloride (1:1)
Notes:
an indirect sympathomimetic. tyramine does not directly activate adrenergic receptors, but it can serve as a substrate for adrenergic uptake systems and monoamine oxidase so it prolongs the actions of adrenergic transmitters. it also provokes transmitter release from adrenergic terminals. tyramine may be a neurotransmitter in some invertebrate nervous systems.
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Glentham Life Sciences Ltd The Chemical, Biochemical & Research Essentials Supplier Glentham Life Sciences is a supplier of fine chemicals and raw materials with warehousing, laboratories and packaging facilities in the UK. With a Glentham Life Sciences account you can view more product details, request quotes and order products online. Email: Info Email: Sales Email: Tech Support Voice: +44 (0) 1225 667798 Fax: +44 (0) 2033 978909 Facebook Twitter Linkedin Google+ News Distribution Products List: View Product(s): GE5178 Tyramine hydrochloride
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| CAS Number: | 60-19-5 |  3D/inchi
|
| ECHA EINECS - REACH Pre-Reg: | 200-462-5 | |
| FDA UNII: | Z5KDH3H147 | |
| Beilstein Number: | 3627058 | |
| MDL: | MFCD00012901 | |
| Molecular Weight: | 173.64184000 | |
| Formula: | C8 H12 Cl N O | |
| BioActivity Summary: | listing | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: pharmaceuticals / chemical synthisis
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
Physical Properties:
| Assay: | 95.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Boiling Point: | 325.20 °C. @ 760.00 mm Hg (est) |
| Vapor Pressure: | 0.000123 mmHg @ 25.00 °C. (est) |
| Flash Point: | 247.00 °F. TCC ( 119.20 °C. ) (est) |
| logP (o/w): | 0.722 (est) |
| Soluble in: | |
| water, 1e+006 mg/L @ 25 °C (est) | |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| None found |
Suppliers:
| BOC Sciences |
| For experimental / research use only. |
| Tyramine-d4 HCl
Odor: characteristic Use: Tyramine-d4 HCl is the labeled analogue of Tyramine HCl. Tyramine is a catecholamine releasing agent that binds to both TAAR1 and TAAR2 as an agonist. Tyramine is derived from Tyrosine. |
| Glentham Life Sciences |
| Tyramine hydrochloride |
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| Tyramine Hydrochloride |
| Sigma-Aldrich: Sigma |
| For experimental / research use only. |
| Tyramine hydrochloride ≥98% |
| TCI AMERICA |
| For experimental / research use only. |
| Tyramine Hydrochloride >98.0%(T) |
Safety Information:
| Preferred SDS: View | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
|
intraperitoneal-mouse LD50 710 mg/kg Toxicology and Applied Pharmacology. Vol. 28, Pg. 227, 1974. intravenous-mouse LD50 208 mg/kg LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD European Journal of Pharmacology. Vol. 9, Pg. 289, 1970. unreported-mouse LDLo 2750 mg/kg Journal of Pharmacology and Experimental Therapeutics. Vol. 8, Pg. 126, 1916. | |
| Dermal Toxicity: | |
|
subcutaneous-guinea pig LDLo 1044 mg/kg BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE Journal of Pharmacology and Experimental Therapeutics. Vol. 47, Pg. 339, 1933. | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | pharmaceuticals / chemical synthisis | ||
| Recommendation for tyramine hydrochloride usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for tyramine hydrochloride flavor usage levels up to: | |||
| not for flavor use. | |||
Safety References:
| EPI System: | View |
| Chemical Carcinogenesis Research Information System: | Search |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA Substance Registry Services (TSCA): | 60-19-5 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 66449 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 3 |
| 4-(2-aminoethyl)phenol;hydrochloride | |
| Chemidplus: | 0000060195 |
| RTECS: | SJ6050000 for cas# 60-19-5 |
References:
| 4-(2-aminoethyl)phenol;hydrochloride | |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 60-19-5 |
| Pubchem (cid): | 66449 |
| Pubchem (sid): | 135025578 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| CHEMBL: | View |
| Golm Metabolome Database: | Search |
| HMDB (The Human Metabolome Database): | Search |
| Export Tariff Code: | 2922.50.4000 |
| ChemSpider: | View |
| Wikipedia: | View |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| None Found |
Occurrence (nature, food, other): note
| not found in nature |
Synonyms:
| 4-(2- | amino-ethyl)-phenol;hydrochloride |
| p-(2- | aminoethyl)-phenol hydrochloride |
| 4-(2- | aminoethyl)phenol hydrochloride |
| 4-(2- | aminoethyl)phenol hydrochloride (1:1) |
| 4-(2- | aminoethyl)phenol, chloride |
| 4-(2- | aminoethyl)phenol;hydrochloride |
| 4- | hydroxyphenethylamine hydrochloride |
| 4- | hydroxyphenethylammonium chloride |
| 2-(4- | hydroxyphenyl)ethylamine hydrochloride |
| 4- | hydroxyphenylethylamine hydrochloride |
| phenol, 4-(2-aminoethyl)-, hydrochloride | |
| phenol, 4-(2-aminoethyl)-, hydrochloride (1:1) | |
| phenol, p-(2-aminoethyl)-, hydrochloride (8CI) | |
| phenol, p-(2-aminoethyl)-, monochloride | |
| phenol, p-(2-aminoethyl)-, monohydrochloride | |
| p- | tryamine hydrochloride |
| tyraminehydrochloride |