pivalic acid, 75-98-9

Articles:

PubMed:	What Controls the Magnetic Exchange Interaction in Mixed- and Homo-Valent Mn7 Disc-Like Clusters? A Theoretical Perspective.
PubMed:	Metal distribution and disorder in the crystal structure of [NH2Et2][Cr7MF8((t)BuCO2)16] wheel molecules for M = Mn, Fe, Co, Ni, Cu, Zn and Cd.
PubMed:	A series of cobalt and nickel clusters based on thiol-containing ligands accompanied by in situ ligand formation.
PubMed:	4,4',4″-Trimethyl-2,2':6',2″-terpyridine by Oxidative Coupling of 4-Picoline.
PubMed:	Newborn hypocarnitinemia due to long-term transplacental pivalic acid passage.
PubMed:	Tetrametallic lanthanide(III) phosphonate cages: synthetic, structural and magnetic studies.
PubMed:	Ruthenium-catalyzed highly regio- and stereoselective hydroarylation of aromatic sulfoxides with alkynes via C-H bond activation.
PubMed:	Synthesis, structure and magnetic properties of phenylhydroxamate-based coordination clusters.
PubMed:	A family of novel Mn₃Ln₄ clusters displaying single-molecule magnet behavior.
PubMed:	Hexanuclear, heterometallic, Ni₃Ln₃ complexes possessing O-capped homo- and heterometallic structural subunits: SMM behavior of the dysprosium analogue.
PubMed:	Preclinical evaluation of 3-18F-fluoro-2,2-dimethylpropionic acid as an imaging agent for tumor detection.
PubMed:	The coordination chemistry and magnetism of some 3d-4f and 4f amino-polyalcohol compounds.
PubMed:	Structures and magnetic properties of two analogous Dy6 wheels with electron-donation and -withdrawal effects.
PubMed:	Enantiospecific, nickel-catalyzed cross-couplings of allylic pivalates and arylboroxines.
PubMed:	Hydroxide-free cubane-shaped tetranuclear [Ln4] complexes.
PubMed:	Ruthenium-catalyzed hydroarylation of anilides with alkynes: an efficient route to ortho-alkenylated anilines.
PubMed:	In situ generation of palladium nanoparticles: ligand-free palladium catalyzed pivalic acid assisted carbonylative Suzuki reactions at ambient conditions.
PubMed:	Synthesis and characterization of nickel(II) phosphonate complexes utilizing pyridonates and carboxylates as co-ligands.
PubMed:	Amides in one pot from carboxylic acids and amines via sulfinylamides.
PubMed:	Surprising causes of C5-carnitine false positive results in newborn screening.
PubMed:	Application of a second-tier newborn screening assay for c5 isoforms.
PubMed:	Isolation, structure, and reactivity of an arylnickel(II) pivalate complex in catalytic C-H/C-O biaryl coupling.
PubMed:	Tetranuclear lanthanide (III) complexes containing dimeric subunits: single-molecule magnet behavior for the Dy4 analogue.
PubMed:	Influence of mitochondrion-toxic agents on the cardiovascular system.
PubMed:	Octametallic 4f-phosphonate horseshoes.
PubMed:	C-H functionalization of cyclopropanes: a practical approach employing a picolinamide auxiliary.
PubMed:	Developments in Meyers' lactamization methodology: en route to bi(hetero)aryl structures with defined axial chirality.
PubMed:	Octanuclear {Ln(III)8}(Ln = Gd, Tb, Dy, Ho) macrocyclic complexes in a cyclooctadiene-like conformation: manifestation of slow relaxation of magnetization in the Dy(III) derivative.
PubMed:	UPLC-MS/MS analysis of C5-acylcarnitines in dried blood spots.
PubMed:	Nickel-catalyzed cross-couplings of benzylic pivalates with arylboroxines: stereospecific formation of diarylalkanes and triarylmethanes.
PubMed:	Slow magnetic relaxation in two new 1D/0D Dy(III) complexes with a sterically hindered carboxylate ligand.
PubMed:	Octanuclear Mn(III)6Mn(II)Ln (Ln = Gd, Dy and Er) clusters with a novel core topology: syntheses, structures, and magnetic properties.
PubMed:	Palladium-catalyzed asymmetric allylic alkylation of 3-aryloxindoles with allylidene dipivalate: a useful enol pivalate product.
PubMed:	Comproportionation reactions to manganese(III/IV) pivalate clusters: a new half-integer spin single-molecule magnet.
PubMed:	Syntheses, structures and magnetic properties of a family of heterometallic [Mn(II)2Mn(III)2Ln(III)2] clusters.
PubMed:	Ruthenium-catalyzed highly regio- and stereoselective hydroarylation of aryl carbamates with alkynes via C-H bond activation.
PubMed:	Fast Pd- and Pd/Cu-catalyzed direct C-H arylation of cyclic nitrones. Application to the synthesis of enantiopure quaternary α-amino esters.
PubMed:	Cu-catalyzed reaction of 1,2-dihalobenzenes with 1,3-cyclohexanediones for the synthesis of 3,4-dihydrodibenzo[b,d]furan-1(2H)-ones.
PubMed:	Biosynthesis and metabolic pathways of pivalic acid.
PubMed:	Primary carnitine deficiency and pivalic acid exposure causing encephalopathy and fatal cardiac events.
PubMed:	Rapid acyl migration between pyrogallyl 1,2- and 1,3-dipivaloates.
PubMed:	A short-term high-dose administration of sodium pivalate impairs pyruvate metabolism without affecting cardiac function.
PubMed:	Electronic structure and magnetic properties of a molecular octanuclear chromium-based ring.
PubMed:	Novel coenzyme B12-dependent interconversion of isovaleryl-CoA and pivalyl-CoA.
PubMed:	Palladium(II)-catalyzed direct intermolecular alkenylation of chromones.
PubMed:	Structure, magnetism and theory of a family of nonanuclear Cu(II)5Ln(III)4-triethanolamine clusters displaying single-molecule magnet behaviour.
PubMed:	Multifunctional 5-aminolevulinic acid prodrugs activating diverse cell-death pathways.
PubMed:	Pivalic acid acts as a starter unit in a fatty acid and antibiotic biosynthetic pathway in Alicyclobacillus, Rhodococcus and Streptomyces.
PubMed:	Continuous synthesis of tert-butyl peroxypivalate using a single-channel microreactor equipped with orifices as emulsification units.
PubMed:	Nickel-catalyzed reductive cleavage of aryl-oxygen bonds in alkoxy- and pivaloxyarenes using hydrosilanes as a mild reducing agent.
PubMed:	Intramolecular palladium-catalyzed alkane C-H arylation from aryl chlorides.
PubMed:	Rapid determination of C4-acylcarnitine and C5-acylcarnitine isomers in plasma and dried blood spots by UPLC-MS/MS as a second tier test following flow-injection MS/MS acylcarnitine profile analysis.
PubMed:	Synthesis, structures and magnetic properties of a series of 3d-4f tetranuclear Co(II)₂Ln(III)₂ cubanes.
PubMed:	Nickel-catalyzed amination of aryl pivalates by the cleavage of aryl C-O bonds.
PubMed:	An efficient protocol for alcohol protection under solvent- and catalyst-free conditions.
PubMed:	Recognition of carboxylate anions and carboxylic acids by selenium-based new chromogenic fluorescent sensor: a remarkable fluorescence enhancement of hindered carboxylates.
PubMed:	WITHDRAWN: Design and synthesis of pivalic acid linked tacrine-NO donor hybrids as novel anti-Alzheimer drug candidates.
PubMed:	Children's toxicology from bench to bed--Liver injury (1): Drug-induced metabolic disturbance--toxicity of 5-FU for pyrimidine metabolic disorders and pivalic acid for carnitine metabolism.
PubMed:	Modelling the magnetic behaviour of square-pyramidal Co(II)5 aggregates: tuning SMM behaviour through variations in the ligand shell.
PubMed:	Interaction between pivaloylcarnitine and L-carnitine transport into L6 cells overexpressing hOCTN2.
PubMed:	Tridecanuclear [Mn(III)5Ln(III)8] complexes derived from N-(t)butyl-diethanolamine: synthesis, structures, and magnetic properties.
PubMed:	C(aryl)-O activation of aryl carboxylates in nickel-catalyzed biaryl syntheses.
PubMed:	Establishment of broadly applicable reaction conditions for the palladium-catalyzed direct arylation of heteroatom-containing aromatic compounds.
PubMed:	Phosphine-free, palladium-catalyzed arylation of heterocycles through C-H bond activation with pivalic acid as a cocatalyst.
PubMed:	Cross-coupling of aryl/alkenyl pivalates with organozinc reagents through nickel-catalyzed C-O bond activation under mild reaction conditions.
PubMed:	Novel multifunctional acyloxyalkyl ester prodrugs of 5-aminolevulinic acid display improved anticancer activity independent and dependent on photoactivation.
PubMed:	Role of Na+/L-carnitine transporter (OCTN2) in renal handling of pivaloylcarnitine and valproylcarnitine formed during pivalic acid-containing prodrugs and valproic acid treatment.
PubMed:	Enantioselective formation of ibuprofen-S-acyl-glutathione in vitro in incubations of ibuprofen with rat hepatocytes.
PubMed:	Intramolecular Pd(II)-catalyzed oxidative biaryl synthesis under air: reaction development and scope.
PubMed:	Au-catalyzed synthesis of (1Z,3E)-2-pivaloxy-1,3-dienes from propargylic pivalates.
PubMed:	Ion-pair interaction in pyridinium carboxylate solutions.
PubMed:	Protic ionic liquids: physicochemical properties and behavior as amphiphile self-assembly solvents.
PubMed:	Toward a magnetostructural correlation for a family of Mn6 SMMs.
PubMed:	Carnitine-associated encephalopathy caused by long-term treatment with an antibiotic containing pivalic acid.
PubMed:	5(6)-carboxyfluorescein revisited: new protecting group, separation of isomers, and their spectral properties on oligonucleotides.
PubMed:	Pivalate lowers litter sizes and weights in female rats independent of its effect on carnitine status.
PubMed:	Chromium-catalyzed arylmagnesiation of alkynes.
PubMed:	Palladium-catalyzed benzene arylation: incorporation of catalytic pivalic acid as a proton shuttle and a key element in catalyst design.
PubMed:	Pyrones to pyrans: enantioselective radical additions to acyloxy pyrones.
PubMed:	Magnesium bistrifluoromethanesulfonimide as a new and efficient acylation catalyst.
PubMed:	Involvement of recognition and interaction of carnitine transporter in the decrease of L-carnitine concentration induced by pivalic acid and valproic acid.
PubMed:	Hypocarnitinaemia induced by sodium pivalate in the rat is associated with left ventricular dysfunction and impaired energy metabolism.
PubMed:	Cytotoxicity of pivoxil esters of antiviral acyclic nucleoside phosphonates: adefovir dipivoxil versus adefovir.
PubMed:	Photocatalytic oxygenation of pivalic acid with molecular oxygen via photoinduced electron transfer using 10-methylacridinium ions.
PubMed:	Possible mechanism for species difference on the toxicity of pivalic acid between dogs and rats.
PubMed:	1,1,1-Tris(hydroxymethyl)propane in manganese carboxylate chemistry: synthesis, structure and magnetic properties of a mixed-valence [MnIII4MnII4] cluster featuring the novel [MnIII4MnII4(mu3-OR)6(mu2-OR)8]6+ core.
PubMed:	2-Benzyl and 2-phenyl-3-hydroxypropyl pivalates as protein kinase C ligands.
PubMed:	[131I]Iodoazomycin arabinoside for low-dose-rate isotope radiotherapy: radiolabeling, stability, long-term whole-body clearance and radiation dosimetry estimates in mice.
PubMed:	Carnitine deficiency and supplementation do not affect the gene expression of carnitine biosynthetic enzymes in rats.
PubMed:	Isoelectric buffers for capillary electrophoresis. 2. Bismorpholine derivative of a carboxylic acid as a low molecular weight isoelectric buffer.
PubMed:	Carnitine deficiency disorders in children.
PubMed:	Synthesis and studies of a trinuclear Mn(II) carboxylate complex.
PubMed:	Degradation of isooctane by Mycobacterium austroafricanum IFP 2173: growth and catabolic pathway.
PubMed:	A mild and efficient protocol for the conversion of carboxylic acids to olefins by a catalytic decarbonylative elimination reaction.
PubMed:	A stereodivergent approach to chiral nonracemic N-protected alpha,alpha-dialkylated amino acids.
PubMed:	Anaerobic mineralization of quaternary carbon atoms: isolation of denitrifying bacteria on pivalic acid (2,2-dimethylpropionic acid).
PubMed:	Selective desensitization of jasmonate- and pH-dependent signaling in the induction of benzophenanthridine biosynthesis in cells of Eschscholzia californica.
PubMed:	Pivalate-generating prodrugs and carnitine homeostasis in man.
PubMed:	Host-guest chemistry of the chromium-wheel complex [Cr8F8(tBuCO2)16]: prediction of inclusion capabilities by using an electrostatic potential distribution determined by modeling synchrotron X-ray structure factors at 16 K.
PubMed:	Resorcinarenes with 2-benzimidazolone bridges: self-aggregation, self-assembled dimeric capsules, and guest encapsulation.
PubMed:	Application of a surface plasmon resonance sensor to analyses of amine compounds with the use of a polymer film and an acid-base reaction.
PubMed:	Evidence for tip velocity oscillations in dendritic solidification.
PubMed:	Magnetic anisotropy of the antiferromagnetic ring [Cr8F8Piv16].
PubMed:	Preparative route to glucuronyl donors bearing temporary protecting group at O-3 via 6,3-lactonisation by Bz(2)O or Piv(2)O.
PubMed:	Molecular basis for the synergistic interaction of adriamycin with the formaldehyde-releasing prodrug pivaloyloxymethyl butyrate (AN-9).
PubMed:	The effect of pivalate treatment of pregnant rats on body mass and insulin levels in the adult offspring.
PubMed:	Up-regulation of carnitine transporters helps maintain tissue carnitine levels in carnitine deficiency induced by pivalic acid.
PubMed:	Effect of various levels of supplementation with sodium pivalate on tissue carnitine concentrations and urinary excretion of carnitine in the rat.
PubMed:	Carnitine protects mitochondria and removes toxic acyls from xenobiotics.
PubMed:	Synthesis, characterization, and reactivity of ferrous and ferric oxo/peroxo pivalate complexes in relation to Gif-type oxygenation of substrates.
PubMed:	Effect of carbonate salts on the kinetics of acid-catalyzed dimerization of adefovir dipivoxil.
PubMed:	Functional and pharmacological characterization of human Na(+)-carnitine cotransporter hOCTN2.
PubMed:	Formation of carboxylic acids from small alkanes in zeolite H-ZSM-5
PubMed:	Modifications in electrospray tandem mass spectrometry for a neonatal-screening pilot study in Japan.
PubMed:	Shifts of intracellular pH distribution as a part of the signal mechanism leading to the elicitation of benzophenanthridine alkaloids . Phytoalexin biosynthesis in cultured cells of eschscholtzia californica
PubMed:	Diagnosis of isovaleric acidaemia by tandem mass spectrometry: false positive result due to pivaloylcarnitine in a newborn screening programme.
PubMed:	14C-NaVP and 14C-PEV repeated dose study in rat. Pharmacokinetic study in rats after repeated oral administrations of 14C-valproic acid sodium salt and 14C-valproic acid pivaloyl oxymethyl ester.
PubMed:	Crystal forms of piroxicam pivalate: preparation and characterization of two polymorphs.
PubMed:	Successful lowering of epididymal carnitine by administration of pivalate to rats.
PubMed:	Comparison of in vitro carnitine and glycine conjugation with branched-side chain and cyclic side chain carboxylic acids in rats.
PubMed:	Effects of pivalic acid and sodium pivalate on L-carnitine concentrations in the cauda epididymidis and on male fertility in the hamster.
PubMed:	Pivalic acid-induced carnitine deficiency and physical exercise in humans.
PubMed:	Carnitine supplementation ameliorates the steatosis and ketosis induced by pivalate in rats.
PubMed:	beta-Hydroxybutyrate oxidation is reduced and hepatic balance of ketone bodies and free fatty acids is unaltered in carnitine-depleted, pivalate-treated rats.
PubMed:	[Influence of multiple-dose administration of cefetamet pivoxil on blood and urinary concentrations of carnitine and effects of simultaneous administration of carnitine with cefetamet pivoxil].
PubMed:	A new esterase for the cleavage of pivalic acid-containing prodrug esters of cephalosporins.
PubMed:	Pivalate affects carnitine status but causes no severe metabolic changes in rat liver.
PubMed:	Gas chromatography/combustion/isotope ratio mass spectrometric comparison of N-acetyl- and N-pivaloyl amino acid esters to measure 15N isotopic abundances in physiological samples: a pilot study on amino acid synthesis in the upper gastro-intestinal tract of minipigs.
PubMed:	Induction of peroxisomal beta-oxidation and P-450 4A-dependent activities by pivalic and trichloroacetic acid in rat liver and kidney.
PubMed:	Selective depletion of mitochondrial glutathione content by pivalic acid and valproic acid in rat liver: possibility of a common mechanism.
PubMed:	Transient reduction of human left ventricular mass in carnitine depletion induced by antibiotics containing pivalic acid.
PubMed:	Formation of pivaloylcarnitine in isolated rat heart cells.
PubMed:	L-carnitine improvement of cardiac function is associated with a stimulation in glucose but not fatty acid metabolism in carnitine-deficient hearts.
PubMed:	Disposition of S-1108, a new oral cephem antibiotic, and metabolic fate of pivalic acid liberated from [pivaloyl-14C]S-1108 in rats and dogs.
PubMed:	Effect of short-term treatment with pivalic acid containing antibiotics on serum carnitine concentration--a risk irrespective of age.
PubMed:	Increased pivaloylcarnitine in the liver of the sodium pivalate treated rat exposed to clofibrate.
PubMed:	Fatty acid oxidation and cardiac function in the sodium pivalate model of secondary carnitine deficiency.
PubMed:	L-propionylcarnitine effects on cardiac carnitine content and function in secondary carnitine deficiency.
PubMed:	Formation of pivaloylcarnitine in heart and brown adipose tissue in the rat.
PubMed:	Carnitine depletion in rat pups of lactating mothers given sodium pivalate.
PubMed:	Alteration of ammonia and carnitine levels in short-term treatment with pivalic acid-containing prodrug.
PubMed:	Sodium pivalate reduces cardiac carnitine content and increases glucose oxidation without affecting cardiac functional capacity.
PubMed:	Mean shape of three-dimensional dendrites: A comparison of pivalic acid and ammonium chloride.
PubMed:	Impaired ketogenesis in carnitine depletion caused by short-term administration of pivalic acid prodrug.
PubMed:	Erratum: Dendritic sidebranching with periodic localized perturbations: Directional solidification of pivalic acid-coumarin 152 mixtures
PubMed:	Preferential elimination of pivalate with supplemental carnitine via formation of pivaloylcarnitine in man.
PubMed:	[Effect of cefditoren pivoxil on carnitine metabolism in pediatric patients].
PubMed:	Comment on "Surface-tension-anisotropy measurements of succinonitrile and pivalic acid: Comparison with microscopic solvability theory"
PubMed:	Modulation of enantioselective metabolism and inversion of ibuprofen by xenobiotics in isolated rat hepatocytes.
PubMed:	Solvent and steric effects on the extraction of copper(II) with pivalic acid.
PubMed:	Dendritic sidebranching with periodic localized perturbations: Directional solidification of pivalic acid-coumarin 152 mixtures.
PubMed:	Carnitine status and safety after administration of S-1108, a new oral cephem, to patients.
PubMed:	Carnitine deficiency associated with long-term pivampicillin treatment: the effect of a replacement therapy regime.
PubMed:	Determination of pivaloylcarnitine in human plasma and urine by high-performance liquid chromatography with fluorescence detection.
PubMed:	Effects of pivalic acid-containing prodrugs on carnitine homeostasis and on response to fasting in children.
PubMed:	Cleavage and deprotection of peptides on MBHA-resin with hydrogen bromide.
PubMed:	Surface-tension-anisotropy measurements of succinonitrile and pivalic acid: Comparison with microscopic solvability theory.
PubMed:	Phase I clinical studies of S-1108: safety and pharmacokinetics in a multiple-administration study with special emphasis on the influence on carnitine body stores.
PubMed:	Metabolism of S-1108, a new oral cephem antibiotic, and metabolic profiles of its metabolites in humans.
PubMed:	Fmoc-amino acid chlorides in solid phase synthesis of opioid peptides.
PubMed:	Sodium pivalate treatment reduces tissue carnitines and enhances ketosis in rats.
PubMed:	Metabolic effects of pivalate in isolated rat hepatocytes.
PubMed:	[Antibiotics containing pivalic acid and carnitine deficiency. A report of the present status--therapeutic recommendations].
PubMed:	Partial purification of esterases from rabbit serum and their use in regioselective deacylations of sugars.
PubMed:	Carnitine supplementation in pivampicillin treatment.
PubMed:	Evidence for acyloxymethyl esters of pyrimidine 5'-deoxyribonucleotides as extracellular sources of active 5'-deoxyribonucleotides in cultured cells.
PubMed:	Carnitine deficiency induced by pivampicillin and pivmecillinam therapy.
PubMed:	Characterization of apical and basolateral membrane conductances of rat inner medullary collecting duct.
PubMed:	Potential tumor- or organ-imaging agents. 29. Radioiodinated esters and amides of 20-hydroxy- and 20-aminopregn-5-en-3 beta-ols.
PubMed:	Identification and quantification of ethylene glycol and diethylene glycol in plasma using gas chromatography-mass spectrometry.
PubMed:	Pivampicillin-promoted excretion of pivaloylcarnitine in humans.
PubMed:	Improvement of the oral bioavailability of naltrexone in dogs: a prodrug approach.
PubMed:	The simultaneous determination of chloroformates and phosgene at low concentrations in air using a solid sorbent sampling--gas chromatographic procedure.
PubMed:	[Pharmacodynamics of etilfrine pivilate in the orthostatic syndrome].
PubMed:	Carnitine and glucuronic acid conjugates of pivalic acid.
PubMed:	Potential tumor or organ-imaging agents, 24. Radioiodinated pregnenolone esters.
PubMed:	Metabolism of methyldopa in man after oral administration of the pivaloyloxyethyl ester.
PubMed:	Comparison of ocular disposition of free pivalic acid and pivalic acid esterified in dipivefrin.
PubMed:	Carcinogenicity of some pyrrolic pyrrolizidine alkaloid metabolites and analogues.
PubMed:	Cytotoxicity of pivalylphenylephrine and pivalic acid to corneal endothelium.
PubMed:	Dipivefrin: current concepts.
PubMed:	Metabolism of quaternary carbon compounds: 2,2-dimethylheptane and tertbutylbenzene.
PubMed:	The use of pivalic acid as a reference substance in measurements of production of volatile fatty acids by rumen micro-organisms in vitro.
PubMed:	New inhibitors of methane production by rumen micro-organisms. Development and testing of inhibitors in vitro.
PubMed:	New pivalic acid esters of synthetic corticosteroids with high local anti-inflammatory activity.