| PubMed: | Suppression of Cytosolic NADPH Pool by Thionicotinamide Increases Oxidative Stress and Synergizes with Chemotherapy. |
| PubMed: | Boronic acid-containing CXCR1/2 antagonists: Optimization of metabolic stability, in vivo evaluation, and a proposed receptor binding model. |
| PubMed: | Electrochemistry, surface plasmon resonance, and quartz crystal microbalance: an associative study on cytochrome c adsorption on pyridine tail-group monolayers on gold. |
| PubMed: | Spectrophotometric method for the assay of steroid 5α-reductase activity of rat liver and prostate microsomes. |
| PubMed: | [Development of super high-sensitive measurement of proteins by combination of ELISA and enzyme cycling methods]. |
| PubMed: | Enhanced degradation of dihydrofolate reductase through inhibition of NAD kinase by nicotinamide analogs. |
| PubMed: | Thermodynamic, kinetic, surface pKa, and structural aspects of self-assembled monolayers of thio compounds on gold. |
| PubMed: | Ascorbic acid reduction of compound I of mammalian catalases proceeds via specific binding to the NADPH binding pocket. |
| PubMed: | Structural and kinetic isotope effect studies of nicotinamidase (Pnc1) from Saccharomyces cerevisiae. |
| PubMed: | Elucidating the structure-activity relationships of the vasorelaxation and antioxidation properties of thionicotinic acid derivatives. |
| PubMed: | Novel bUT-B2 urea transporter isoform is constitutively activated. |
| PubMed: | Transhydrogenation reactions catalyzed by mitochondrial NADH-ubiquinone oxidoreductase (Complex I). |
| PubMed: | Determinants of substrate specificity for saccharopine dehydrogenase from Saccharomyces cerevisiae. |
| PubMed: | Molecular cloning and characterization of a novel lactate dehydrogenase gene from Clonorchis sinensis. |
| PubMed: | Electron transfer kinetics and mechanistic study of the thionicotinamide coordinated to the pentacyanoferrate(III)/(II) complexes: a model system for the in vitro activation of thioamides anti-tuberculosis drugs. |
| PubMed: | Kinetic study of the enzymatic cycling reaction conducted with 3alpha-hydroxysteroid dehydrogenase in the presence of excessive thio-NAD(+) and NADH. |
| PubMed: | Urea transport in MDCK cells that are stably transfected with UT-A1. |
| PubMed: | Interactions between transhydrogenase and thio-nicotinamide Analogues of NAD(H) and NADP(H) underline the importance of nucleotide conformational changes in coupling to proton translocation. |
| PubMed: | EPYLRFamide-mediated reduction of acetylcholine-induced inward currents in Helix lucorum-identified neurones: role of NAADP-dependent and IP3-dependent Ca2+ release from internal stores, calmodulin and Ca2+/calmodulin-dependent protein kinase II. |
| PubMed: | Tartrate dehydrogenase catalyzes the stepwise oxidative decarboxylation of D-malate with both NAD and thio-NAD. |
| PubMed: | Structures of D-glyceraldehyde-3-phosphate dehydrogenase complexed with coenzyme analogues. |
| PubMed: | The determination of ketone bodies: preanalytical, analytical and physiological considerations. |
| PubMed: | Mycobacterium tuberculosis lipoamide dehydrogenase is encoded by Rv0462 and not by the lpdA or lpdB genes. |
| PubMed: | Interaction of NADP(H) with oxidized and reduced P450 reductase during catalysis. Studies with nucleotide analogues. |
| PubMed: | UT-A urea transporter protein expressed in liver: upregulation by uremia. |
| PubMed: | InsP3, but not novel Ca2+ releasers, contributes to agonist-initiated contraction in rabbit airway smooth muscle. |
| PubMed: | Thio-NADP is not an antagonist of NAADP. |
| PubMed: | Azotobacter vinelandii glucose 6-phosphate dehydrogenase properties of NAD- and NADP-linked reactions. |
| PubMed: | Nicotinate-adenine dinucleotide phosphate-induced Ca(2+)-release does not behave as a Ca(2+)-induced Ca(2+)-release system. |
| PubMed: | Palmitoyl-CoA potentiates the Ca2+ release elicited by cyclic ADP-ribose. |
| PubMed: | Purification and characterization of Azotobacter vinelandii glucose-6-phosphate dehydrogenase: dual coenzyme specificity. |
| PubMed: | Nicotinate adenine dinucleotide phosphate (NAADP) triggers a specific calcium release system in sea urchin eggs. |
| PubMed: | The urease inhibitor acetohydroxamic acid is transported by the urea pathway in rat terminal IMCD. |
| PubMed: | Crystal structures of chicken liver dihydrofolate reductase: binary thioNADP+ and ternary thioNADP+.biopterin complexes. |
| PubMed: | Selectivity in the binding of NAD(P)+ analogues to NAD- and NADP-dependent pig heart isocitrate dehydrogenases. A nuclear magnetic resonance study. |
| PubMed: | The effect of methimazole on thioamide bioactivation and toxicity. |
| PubMed: | Multiple isotope effects with alternative dinucleotide substrates as a probe of the malic enzyme reaction. |
| PubMed: | Analogues of NADP(+) as inhibitors and coenzymes for NADP(+) malic enzyme from maize leaves. |
| PubMed: | The S-oxidation of thioamides by rat liver microsomes. |
| PubMed: | Kinetic mechanism of the endogenous lactate dehydrogenase activity of duck epsilon-crystallin. |
| PubMed: | The metabolism of thionicotinamide in the rat. |
| PubMed: | Clinical usefulness of malate dehydrogenase and its mitochondrial isoenzyme in comparison with aspartate aminotransferase and its mitochondrial isoenzyme in sera of patients with liver disease. |
| PubMed: | In vitro evaluation of nicotinamide riboside analogs against Haemophilus influenzae. |
| PubMed: | Distance between the substrate and regulatory reduced coenzyme binding sites of bovine liver glutamate dehydrogenase by resonance energy transfer. |
| PubMed: | Regulation of coenzyme utilization by mitochondrial NAD(P)-dependent malic enzyme. |
| PubMed: | Assay of creatine kinase in microtiter plates using thio-NAD to allow monitoring at 405 nM. |
| PubMed: | ALT reagent with thionicotinamide adenine dinucleotide. |
| PubMed: | Isolation, characterization, and biological activity of ferredoxin-NAD+ reductase from the methane oxidizer Methylosinus trichosporium OB3b. |
| PubMed: | Substrate specificity of nicotinamide methyltransferase isolated from porcine liver. |
| PubMed: | The mechanism of peroxidase-mediated cytotoxicity. II. Role of the heme moiety. |
| PubMed: | Inhibitory effects of niacin and its analogues on induction of ornithine decarboxylase activity by diethylnitrosamine in rat liver. |
| PubMed: | Distances among coenzyme and metal sites of NADP+-dependent isocitrate dehydrogenase using resonance energy transfer. |
| PubMed: | Interactions of nicotinamide-adenine dinucleotide phosphate analogues and fragments with pigeon liver malic enzyme. Synergistic effect between the nicotinamide and adenine moieties. |
| PubMed: | [Simultaneous assay of serum lactate dehydrogenase activities depending on NAD (N) and thio-NAD (T), and the clinical significance of N/T values]. |
| PubMed: | A one-step enzymatic assay for the measurement of 17 beta-hydroxy- and 17-oxo-steroid profiles in biological samples. |
| PubMed: | Simultaneous determination of multiple forms of lactate dehydrogenase based on NAD and thio-NAD. |
| PubMed: | Studies on NADH(NADPH)-cytochrome c reductase (FMN-containing) from yeast: steady-state kinetic properties of the flavoenzyme from top-fermenting ale yeast. |
| PubMed: | Protonation mechanism and location of rate-determining steps for the Ascaris suum nicotinamide adenine dinucleotide-malic enzyme reaction from isotope effects and pH studies. |
| PubMed: | Cytochemical localization of nicotinamide adenine dinucleotide phosphatase (NADPase) in bovine Leydig cells. |
| PubMed: | The redox state of activated bleomycin. |
| PubMed: | Kinetic and spectroscopic studies of transhydrogenase activity and nucleotide site of lipoamide dehydrogenase. |
| PubMed: | Variation of transition-state structure as a function of the nucleotide in reactions catalyzed by dehydrogenases. 2. Formate dehydrogenase. |
| PubMed: | Synthesis and properties of (4-13C)NAD+. Observation of its binding to yeast alcohol dehydrogenase by 13C-NMR spectroscopy. |
| PubMed: | Bovine lens aldehyde dehydrogenase. Kinetics and mechanism. |
| PubMed: | Adenosine diphosphoribose transfer reactions catalyzed by Bungarus fasciatus venom NAD glycohydrolase. |
| PubMed: | Use of transferred nuclear Overhauser effect measurements to compare binding of coenzyme analogues to dihydrofolate reductase. |
| PubMed: | Oxidation of the 17-aldol (20 beta hydroxy-21-aldehyde) intermediate of corticosteroid metabolism to hydroxy acids by homogeneous human liver aldehyde dehydrogenases. |
| PubMed: | Regulation of coenzyme utilization by bovine liver glutamate dehydrogenase: investigations using thionicotinamide analogues of NAD and NADP in a dual wavelength assay. |
| PubMed: | Negative cooperativity between folinic acid and coenzyme in their binding to Lactobacillus casei dihydrofolate reductase. |
| PubMed: | Effects of coenzyme binding on histidine residues of Lactobacillus casei dihydrofolate reductase. |
| PubMed: | Dual nucleotide specificity of bovine glutamate dehydrogenase. The role of negative co-operativity. |
| PubMed: | Energy-linked mitochondrial transhydrogenation from NADPH to NADP analogs. |
| PubMed: | Effect of pH on the mitochondrial energy-linked and non-energy-linked transhydrogenation reactions. |
| PubMed: | Energy-linked transhydrogenation from NADPH to [14C]NADP. |
| PubMed: | Phosphorus-31 nuclear magnetic resonance studies of the binding of oxidized coenzymes to Lactobacillus casei dihydrofolate reductase. |
| PubMed: | Proton nuclear magnetic resonance saturation transfer studies of coenzyme binding to Lactobacillus casei dihydrofolate reductase. |
| PubMed: | Binding of coenzyme analogues to Lactobacillus casei dihydrofolate reductase: binary and ternary complexes. |
| PubMed: | Self-inactivation of an erythrocyte NAD glycohydrolase. |
| PubMed: | Kinetic studies of multifunctional reactions catalysed by lipoamide dehydrogenase. |
| PubMed: | Simultaneous analysis of NAD- and NADP-linked activities of dual nucleotide-specific dehydrogenases. Application to Leuconostoc mesenteroides glucose-6-phosphate dehydrogenase. |
| PubMed: | Mercury complexes of thionicotinamide adenine dinucleotide. |
| PubMed: | Fluorescence properties of reduced thionicotinamide--adenine dinucleotide and of its complex with octopine dehydrogenase. |
| PubMed: | Circular dichroic properties and conformation of thionicotinamide dinucleotides bound to horse-liver alcohol dehydrogenase. |
| PubMed: | Circular dichroic properties and conformation of thionicotinamide dinucleotides. |
| PubMed: | Further studies on the properties of glucose 6-phosphate dehydrogenase from the coccidium Eimeria stiedai (Protozoa). |
| PubMed: | Fluorescence energy transfer between heterologous active sites of affinity-labeled aspartokinase of Escherichia coli. |
| PubMed: | Application of nicotin amide-adenine dinucleotide analogs for clinical enzymology: alcohol dehydrogenase activity in liver injury. |
| PubMed: | Application of nicotinamide-adenine dinucleotide analogs for clinical enzymology: a spectrophotometric method for clinical analysis of lactate dehydrogenase patterns with the use of a nicotinamide-adenine dinucleotide analog. |
| PubMed: | Demonstration and possible function of NADH:NAD+ transhydrogenase from ascaris muscle mitochondria. |
| PubMed: | Human liver akdehyde dehydrogenase. Kinetics of aldehyde oxidation. |
| PubMed: | Treatment of psoriasis with 6-aminonicotinamide. |
| PubMed: | Separation behaviour of nicotinamide and thionicotinamide derivatives on Dowex 1-X8. |
| PubMed: | Covalent binding of 3-pyridinealdehyde nicotinamide adenine dinucleotide and substrate to glyceraldehyde 3-phosphate dehydrogenase. |
| PubMed: | 3Alpha-hydroxysteroid dehydrogenase from Pseudomonas testosteroni: kinetic properties with NAD and its thionicotinamide analogue. |
| PubMed: | Thionicotinamide-NADP, a nucleotide analog interfering with ferredoxin-NADP reductase-ferredoxin interaction. |
| PubMed: | Carbohydrate metabolism during morphogenesis of Coprinus lagopus (sensu Buller). |
| PubMed: | [Pharmacologic and biochemical properties of thionicotinamide (thio-NA) and its NAD (P)-analogues]. |
| PubMed: | CO(2) Metabolism in Corn Roots. II. Intracellular Distribution of Enzymes. |
| PubMed: | Nicotinamide-adenine dinucleotide pyrophosphatase in the growing and aging mosquito. |
| PubMed: | Comparative aspects of some bacterial dehydrogenases and transhydrogenases. |
| PubMed: | THE THIONICOTINAMIDE ANALOGS OF DPN AND TPN. II. ENZYME STUDIES. |
| PubMed: | THE THIONICOTINAMIDE ANALOGS OF DPN AND TPN. I. PREPARATION AND ANALYSIS. |
| PubMed: | Coenzyme analogs. II. Photochemical inactivation of reducd thionicotinamide adenine dinucleotide. |
| PubMed: | Coenzyme analogs. I. Preparation and properties of thionicotinamide methiodide. |