sodium selenite
selenious acid, sodium salt (2:1)
 
Notes:
selenious acid, disodium salt. it is used therapeutically to supply the trace element selenium.
  • American International Chemical, LLC.
    • American International Chemical, Inc.
      Consistent sources
      North American supplier for globally sourced ingredients.
      AIC is a Westborough, MA based ISO Certified sales and marketing company serving the food, pharmaceutical, nutritional, personal care, biotech, and industrial markets of North America since 1972. Our success is a result of a company culture built on customer needs, along with partnerships with global manufacturers committed to the rigors and demands of the North American market. Our team of Sales Representatives, along with our network of strategically located warehouses are ready to supply product when and where you need it.
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      Product(s):
      SSCAUC Sodium Selenite
       
  • Glentham Life Sciences
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CAS Number: 10102-18-8Picture of molecule3D/inchi
Other(deleted CASRN): 29528-97-0
ECHA EINECS - REACH Pre-Reg: 233-267-9
FDA UNII: HIW548RQ3W
Nikkaji Web: J44.066C
MDL: MFCD00003489
Molecular Weight: 172.93713856
Formula: Na2 O3 Se
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome or firefox)
Category: special dietary and nutritional additives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Appearance: white crystalline (est)
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Melting Point: 710.00 °C. @ 760.00 mm Hg
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
 moisture Sensitive.
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses:
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Suppliers:
American Elements
Sodium Selenite 99%
Odor: characteristic
Use: Sodium Selenite is generally immediately available in most volumes. Hydrate or anhydrous forms may be purchased. High purity, submicron and nanopowder forms may be considered. American Elements produces to many standard grades when applicable, including Mil Spec (military grade); ACS, Reagent and Technical Grade; Food, Agricultural and Pharmaceutical Grade; Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia) and follows applicable ASTM testing standards.
American International Chemical, LLC.
Sodium Selenite
Glentham Life Sciences
Sodium selenite, anhydrous
Indis NV
For experimental / research use only.
Sodium Selenite
Sigma-Aldrich: Sigma
For experimental / research use only.
Sodium selenite BioReagent, suitable for cell culture, ≥98%
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Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50  7 mg/kg
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Toxicology and Applied Pharmacology. Vol. 20, Pg. 89, 1971.

intravenous-rat LD50  3 mg/kg
Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.

oral-rabbit LD50  2.25 mg/kg
Hygiene and Sanitation Vol. 35(1-3), Pg. 176, 1970.

oral-mouse LD50  7.08 mg/kg
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 35(2), Pg. 14, 1970.

intravenous-mouse LD50  5 mg/kg
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES CARDIAC: OTHER CHANGES PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)
Neurotoxicology. Vol. 2, Pg. 383, 1981.

oral-guinea pig LD50  5.06 mg/kg
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 35(2), Pg. 14, 1970.

oral-cattle LDLo  9900 ug/kg
Journal of the American College of Toxicology. Vol. 5(1), Pg. 45, 1986.

parenteral-chicken LD50  8500 ug/kg
Neuropharmacology. Vol. 25, Pg. 493, 1990.

intravenous-dog LD50  1916 ug/kg
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION CARDIAC: ARRHYTHMIAS (INCLUDING CHANGES IN CONDUCTION) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Proceedings of the South Dakota Academy of Science. Vol. 36, Pg. 173, 1957.

oral-guinea pig LD50  5060 ug/kg
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 35(2), Pg. 14, 1970.

oral-man TDLo  24 mg/kg
GASTROINTESTINAL: NAUSEA OR VOMITING GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Veterinary and Human Toxicology. Vol. 39, Pg. 304, 1997.

oral-mouse LD50  7080 ug/kg
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 35(2), Pg. 14, 1970.

intramuscular-rabbit LD50  2530 ug/kg
Archiv fuer Experimentelle Veterinaermedizin. Vol. 30, Pg. 627, 1976.

oral-rabbit LD50  2250 ug/kg
Hygiene and Sanitation Vol. 35(1-3), Pg. 176, 1970.

intraperitoneal-rabbit LDLo  4 mg/kg
Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.

intravenous-rabbit LDLo  1971 ug/kg
Journal of Pharmacology and Experimental Therapeutics. Vol. 33, Pg. 270, 1928.

parenteral-rabbit LDLo  1971 ug/kg
Clinical Toxicology. Vol. 17, Pg. 171, 1980.

parenteral-rat LD50  6570 ug/kg
Clinical Toxicology. Vol. 17, Pg. 171, 1980.

intraperitoneal-rat LDLo  5476 ug/kg
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) LUNGS, THORAX, OR RESPIRATION: CYANOSIS
Journal of Pharmacology and Experimental Therapeutics. Vol. 58, Pg. 454, 1936.

Dermal Toxicity:
subcutaneous-mouse LD50 13 mg/kg
Sangyo Igaku. Japanese Journal of Industrial Health. Vol. 17, Pg. 491, 1975.

subcutaneous-dog LDLo 4 mg/kg
Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.

subcutaneous-rabbit LDLo 6 mg/kg
ENDOCRINE: HYPOGLYCEMIA BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Proceedings of the Society for Experimental Biology and Medicine. Vol. 24, Pg. 251, 1926.

Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: special dietary and nutritional additives
Recommendation for sodium selenite usage levels up to:
 not for fragrance use.
 
Recommendation for sodium selenite flavor usage levels up to:
 not for flavor use.
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Safety References:
European Food Safety Authority (EFSA) reference(s):
Scientific Opinion on the safety and efficacy of selenium compounds (E8) as feed additives for all animal species: sodium selenite (coated granulated preparation), based on a dossier submitted by Doxal Italia S.p.A
View page or View pdf
Safety and efficacy of selenium compounds (E8) as feed additives for all animal species: sodium selenite, based on a dossier submitted by Retorte GmbH Selenium Chemicals and Metals
View page or View pdf
Safety and efficacy of selenium compounds (E8) as feed additives for all animal species: sodium selenite, based on a dossier submitted by Todini and Co SpA
View page or View pdf
EPI System: View
ClinicalTrials.gov: search
Daily Med: search
NIOSH International Chemical Safety Cards: search
Chemical Carcinogenesis Research Information System: Search
AIDS Citations: Search
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EPA GENetic TOXicology: Search
EPA Substance Registry Services (TSCA): 10102-18-8
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 24934
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 2
 disodium selenite
Chemidplus: 0010102188
EPA/NOAA CAMEO: hazardous materials
RTECS: 10102-18-8
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References:
 disodium selenite
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 10102-18-8
Pubchem (cid): 24934
Pubchem (sid): 134989380
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEBI: View
CHEMBL: View
KEGG (GenomeNet): D10530
HMDB (The Human Metabolome Database): Search
Export Tariff Code: 2842.90.0000
FDA Listing of Food Additive Status: View
ChemSpider: View
Wikipedia: View
Formulations/Preparations:
•bo-se liquid (sc, im injections) (schering-plough animal health corp): sodium selenite, 2.19 mgml (1 mg seml); vitamin e, 50 mg (68 u.s.p. units)ml •l-se liquid (sc, im injections) (schering-plough animal health corp): sodium selenite, 2.19 mgml (1 mg seml); vitamin e, 50 mg (68 u.s.p. units)ml •seletoc minicaps and caps capsules (oral) (schering-plough animal health corp): sodium selenite, 2.19 mg (1 mg se); vitamin e, 56.2 mg (68 i.u.) or sodium selenite, 0.548 mg (0.25 mg se); vitamin e, 14 mg (17.1 i.u.) •mu-se liquid (im, sc injection) (schering-plough animal health corp): sodium selenite, 10.95 mg (5 mg se)ml; vitamin e, 50 mg (68 u.s.p units)ml •e-se emulsion (iv, im injection) (schering-plough animal health corp): sodium selenite, 5.48 mg (2.5 mg se)ml; vitamin e, 50 mg (68 i.u.)ml; 250 mg polyoxyethylated vegetable oil, and water for injection. •seletoc injection (im, sc injection) (schering-plough animal health corp): sodium selenite, 2.19 mg (1 mg se)ml; vitamin e, 50 mg (68 i.u.)ml; 100 mg of polyoxyethylated vegetable oil, 1:10,000 thimerosal, and water for injection. •velenium emulsion (im, sc injection) (fort dodge animal health, division of wyeth): sodium selenite, 10.95 mg (5 mg se)ml; vitamin e, 50 mg (68 u.s.p. units)ml
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
 disodium selenite
 disodium selenium trioxide
 natriumselenit
 selenious acid (H2SeO3), disodium salt
 selenious acid disodium salt
 selenious acid, disodium salt
 selenious acid, sodium salt (2:1)
 sodium biselenite
 sodium selenite [NA2630] [Poison]
 sodium selenium oxide
 sodiumselenite
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