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Category: cosmetic agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | white or slightly pink crystals (est) |
| Assay: | 95.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Melting Point: | 142.00 °C. @ 760.00 mm Hg
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| Boiling Point: | 181.50 °C. @ 760.00 mm Hg
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| Flash Point: | 295.00 °F. TCC ( 146.30 °C. ) (est)
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| logP (o/w): | 1.280 |
| Soluble in: |
| | water, 2060 mg/L @ 25 °C (exp) | | | water, 2.64e+004 mg/L @ 25 °C (est) |
Organoleptic Properties:
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
intraperitoneal-cat LDLo 1000 mg/kg LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Journal of Pharmacology and Experimental Therapeutics. Vol. 101, Pg. 119, 1951.
oral-cat LDLo 150 mg/kg Arzneimittel-Forschung. Drug Research. Vol. 5, Pg. 572, 1955.
intraperitoneal-dog LDLo 1000 mg/kg LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Journal of Pharmacology and Experimental Therapeutics. Vol. 101, Pg. 119, 1951.
oral-guinea pig LD50 1730 mg/kg BEHAVIORAL: TREMOR
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 47, Pg. 479, 1958.
intraperitoneal-guinea pig LDLo 1000 mg/kg LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Journal of Pharmacology and Experimental Therapeutics. Vol. 101, Pg. 119, 1951.
intraperitoneal-mouse LD50 180 mg/kg Bollettino Chimico Farmaceutico. Vol. 111, Pg. 293, 1972.
intravenous-mouse LD50 313 mg/kg BEHAVIORAL: GENERAL ANESTHETIC Journal of Pharmacology and Experimental Therapeutics. Vol. 101, Pg. 119, 1951.
oral-mouse LD50 300 mg/kg Arzneimittel-Forschung. Drug Research. Vol. 5, Pg. 572, 1955.
oral-rabbit LD50 3200 mg/kg Arzneimittel-Forschung. Drug Research. Vol. 5, Pg. 572, 1955.
intraperitoneal-rabbit LDLo 1000 mg/kg LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Journal of Pharmacology and Experimental Therapeutics. Vol. 101, Pg. 119, 1951.
intraperitoneal-rat LD50 600 mg/kg Journal of Pharmacology and Experimental Therapeutics. Vol. 108, Pg. 450, 1953.
oral-rat LD50 980 mg/kg LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 47, Pg. 479, 1958.
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| Dermal Toxicity: |
subcutaneous-mouse LD50 300 mg/kg Arzneimittel-Forschung. Drug Research. Vol. 8, Pg. 25, 1958.
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | cosmetic agents |
| Recommendation for salicyl amide usage levels up to: | | | not for fragrance use.
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| Recommendation for salicyl amide flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| CHEBI: | View |
| CHEMBL: | View |
| KEGG (GenomeNet): | D01811 |
| HMDB (The Human Metabolome Database): | Search |
| Export Tariff Code: | 2924.21.4500 |
| ChemSpider: | View |
| Wikipedia: | View |
Formulations/Preparations: •salicylamide, nf capsules, 200 mg, with methapyrilene hydrochloride 50 mg & scopolamine aminoxide hydrobromide 500 ug (sominex); capsules, 324 mg, with methapyrilene hydrochloride 12 mg & scopolamine aminoxide hydrobromide 150 mg (devarex).
•tablets, nf, 230 mg (amid-sal) & 600 mg (salrin); tablets, 200 mg with methapyrilene hydrochloride 25 mg (nytol); with scopolamine aminoxide hydrobromide 250 ug (sominex); tablets, 250 mg with methapyrilene hydrochloride 25 mg & scopolamine hydrobromide 200 ug (sure-sleep).
•liquiprin...oral: soln 60 mgml; salamide...salicim...oral: tablets 300 mg; salrin...oral: tablets 300 & 600 mg.
•grades: technical; nf.
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Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | acket | | | afko-sal | | | algamon | | | algiamida | | | algiamide | | | allevin | | | amid-sal | | | amidosal | | | anamid | | | andasol | | | benesal | | | benzamide, 2-hydroxy- | | | benzamide, o-hydroxy- | | | benzoic acid, 2-hydroxy-, amide | | 2- | carbamoylphenol | | 2- | carboxamidophenol | | | cdial | | | cetamide | | | cymidon | | | dolomide | | | dropsprin | | | eggosalil | | | flarpirina | | 2- | hydroxy-benzamide | | 2- | hydroxybenzamide | | o- | hydroxybenzamide | | ortho- | hydroxybenzamide | | 2- | hydroxybenzoicacidamide | | | liquiprin | | | morsarinas | | | novecyl | | | oramid | | | panithal | | | raspberin | | | rasperin | | | salamide | | | saliamid | | | saliamin | | | salicim | | | salicylamide | | | salicylic acid amide | | | salipur | | | salizell | | | salrin | | | salymid | | | samid | | | serramida | | | urtosal |
Articles:
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