Articles:
| None found yet. Try the PubMed Search. |
beta-longilobine
Notes:
None found
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BOC Sciences Best of Chemicals Supplier Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services. BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies. Email: Marketing US Email: Marketing Email: Sales US Email: Sales Voice: 1-631-485-4226 Fax: 1-631-614-7828 US Voice: 1-631-485-4226 US Fax: 1-631-614-7828 Europe 44-203-286-1088 Facebook Twitter Linkedin Blog Get the App! Product(s): 480-54-6 RETRORSINE Purity >90%
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| CAS Number: | 480-54-6 |  3D/inchi
|
| Other(deleted CASRN): | 1416-49-5 | |
| FDA UNII: | XJ86XWL8IY | |
| XlogP3-AA: | 0.60 (est) | |
| Molecular Weight: | 351.39945000 | |
| Formula: | C18 H25 N O6 | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
Physical Properties:
| Assay: | 95.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Soluble in: | |
| water, 1.002e+005 mg/L @ 25 °C (est) | |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| None found |
Suppliers:
| BOC Sciences |
| For experimental / research use only. |
| RETRORSINE Purity >90% |
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| Retrorsine ≥90% |
| Sigma-Aldrich |
| For experimental / research use only. |
| Retrorsine analytical standard |
Safety Information:
| Preferred SDS: View | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
|
oral-mammal (species unspecified) LDLo 33 mg/kg Pharmacological Reviews. Vol. 22, Pg. 429, 1970. intraperitoneal-mouse LD50 65 mg/kg Pharmazie. Vol. 49, Pg. 934, 1994. intravenous-mouse LD50 59 mg/kg BLOOD: "LYMPHOMA, INCLUDING HODGKIN'S DISEASE" LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), DIFFUSE" LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA Research Today. Vol. 5, Pg. 53, 1949. intraperitoneal-rat LD50 34 mg/kg LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA LIVER: OTHER CHANGES Chemico-Biological Interactions. Vol. 5, Pg. 227, 1972. intravenous-rat LD50 38 mg/kg LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA BLOOD: "LYMPHOMA, INCLUDING HODGKIN'S DISEASE" LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), DIFFUSE" Research Today. Vol. 5, Pg. 53, 1949. oral-rat LD50 34 mg/kg Xenobiotica. Vol. 1, Pg. 563, 1971. unreported-rat LD50 35 mg/kg Cancer Research. Vol. 28, Pg. 2237, 1968. | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | natural substances and extractives | ||
| Recommendation for retrorsine usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for retrorsine flavor usage levels up to: | |||
| not for flavor use. | |||
Safety References:
| European Food Safety Authority (EFSA) reference(s): | |
| Dietary exposure assessment to pyrrolizidine alkaloids in the European population View page or View pdf | |
| EPI System: | View |
| Chemical Carcinogenesis Research Information System: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| Carcinogenic Potency Database: | Search |
| EPA GENetic TOXicology: | Search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 5281743 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 3 |
| Chemidplus: | 0000480546 |
| RTECS: | VH7525000 for cas# 480-54-6 |
References:
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 5281743 |
| Pubchem (sid): | 134974510 |
| Pherobase: | View |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| CHEBI: | View |
| CHEMBL: | View |
| KEGG (GenomeNet): | C10364 |
| HMDB (The Human Metabolome Database): | Search |
| Export Tariff Code: | 2939.90.1000 |
| VCF-Online: | VCF Volatile Compounds in Food |
| ChemSpider: | View |
| Wikipedia: | View |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| None Found |
Occurrence (nature, food, other): note
| senecio scandens Search Trop Picture |
Synonyms:
| 12,18- | dihydroxy-senecionan-11,16-dione |
| trans-15- | ethylidene-12b-hydroxy-12a-hydroxymethyl-13b-methylsenec-1-enine |
| (3Z,5R,6S,14aR,14bR)-3- | ethylidene-6-hydroxy-6-(hydroxymethyl)-5-methyl-3,4,5,6,9,11,13,14,14a,14b-decahydro[1,6]dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione |
| beta- | longilobine |
| senecionan-11,16-dione, 12,18-dihydroxy- (9CI) |