Articles:
oxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one, 2,3,6,7,7a,8,10a,10b-octahydro-1a,5-dimethyl-8-methylene-, (1aR,4E,7aS,10aS,10bS)-
Notes:
None found
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BOC Sciences Best of Chemicals Supplier Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services. BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies. Email: Marketing US Email: Marketing Email: Sales US Email: Sales Voice: 1-631-485-4226 Fax: 1-631-614-7828 US Voice: 1-631-485-4226 US Fax: 1-631-614-7828 Europe 44-203-286-1088 Facebook Twitter Linkedin Blog Get the App! Product(s): 20554-84-1 Parthenolide ≥98% Parthenolide, a kind of sesquiterpene lactone compound, could be used against ischemic injury as an anti-inflammatory drug and has been found to be effective in inducing apoptosis of cancer cells and eradicate cancer stem cells. Parthenolide has anti-inflammatory, antisecretory and spasmolytic activity. It Inhibits the release of various media
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Glentham Life Sciences Ltd The Chemical, Biochemical & Research Essentials Supplier Glentham Life Sciences is a supplier of fine chemicals and raw materials with warehousing, laboratories and packaging facilities in the UK. With a Glentham Life Sciences account you can view more product details, request quotes and order products online. Email: Info Email: Sales Email: Tech Support Voice: +44 (0) 1225 667798 Fax: +44 (0) 2033 978909 Facebook Twitter Linkedin Google+ News Distribution Products List: View Product(s): GP2300 Parthenolide
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| CAS Number: | 20554-84-1 |  3D/inchi
|
| FDA UNII: | 2RDB26I5ZB | |
| MDL: | MFCD00134592 | |
| XlogP3-AA: | 2.30 (est) | |
| Molecular Weight: | 248.32200000 | |
| Formula: | C15 H20 O3 | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
Physical Properties:
| Appearance: | white crystalline solid (est) |
| Assay: | 95.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Melting Point: | 115.00 to 117.00 °C. @ 760.00 mm Hg |
| Boiling Point: | 393.00 to 395.00 °C. @ 760.00 mm Hg |
| Vapor Pressure: | 0.000002 mmHg @ 25.00 °C. (est) |
| Flash Point: | 331.00 °F. TCC ( 166.11 °C. ) |
| logP (o/w): | 2.424 (est) |
| Soluble in: | |
| alcohol | |
| water, 119 mg/L @ 25 °C (est) | |
| Insoluble in: | |
| water | |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| None found |
Suppliers:
| Alfa Biotechnology |
| For experimental / research use only. |
| Parthenolide 98% |
| BOC Sciences |
| For experimental / research use only. |
| Parthenolide ≥98%
Odor: characteristic Use: Parthenolide, a kind of sesquiterpene lactone compound, could be used against ischemic injury as an anti-inflammatory drug and has been found to be effective in inducing apoptosis of cancer cells and eradicate cancer stem cells.
Parthenolide has anti-inflammatory, antisecretory and spasmolytic activity. It Inhibits the release of various media |
| Changsha Organic Herb |
| Feverfew Extract Parthenolide |
| Dalton Pharma Services |
| For experimental / research use only. |
| Parthenolide 95% |
| EMD Millipore |
| For experimental / research use only. |
| Parthenolide, Tanacetum parthenium |
| ExtraSynthese |
| For experimental / research use only. |
| Parthenolide (HPLC) ≥95% |
| Glentham Life Sciences |
| Parthenolide |
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| Parthenolide ≥99% |
| Sigma-Aldrich: Sigma |
| For experimental / research use only. |
| Parthenolide ≥90% |
Safety Information:
| Preferred SDS: View | |
| European information : | |
| Most important hazard(s): | |
| None - None found. | |
|
S 02 - Keep out of the reach of children. S 22 - Do not breath dust. S 24/25 - Avoid contact with skin and eyes. | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
| Not determined | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | natural substances and extractives | ||
| Recommendation for parthenolide usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for parthenolide flavor usage levels up to: | |||
| not for flavor use. | |||
Safety References:
| EPI System: | View |
| Daily Med: | search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 6473881 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 3 |
| Chemidplus: | 0020554841 |
| RTECS: | LY4220000 for cas# 20554-84-1 |
References:
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 6473881 |
| Pubchem (sid): | 135065647 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| KEGG (GenomeNet): | C07609 |
| HMDB (The Human Metabolome Database): | Search |
| FooDB: | FDB005891 |
| Export Tariff Code: | 2932.29.5050 |
| Typical G.C. | |
| VCF-Online: | VCF Volatile Compounds in Food |
| ChemSpider: | View |
| Wikipedia: | View |
| EFSA Update of results on the monitoring of furan levels in food: | Read Report |
| EFSA Previous report: Results on the monitoring of furan levels in food: | Read Report |
| EFSA Report of the CONTAM Panel on provisional findings on furan in food: | Read Report |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| None Found |
Occurrence (nature, food, other): note
| bay laurel leaf Search Trop Picture | |
| chrysanthemum parthenium Search Trop Picture | |
| featherfew Search Trop Picture | |
| feverfew flower oil @ 28.4% Data GC Search Trop Picture | |
| michelia champaca Search Trop Picture | |
| origanum majorana oil @ 2.07% Data GC Search Trop Picture |
Synonyms:
| (E)-(1S,2S,4R,11S)-4,8- | dimethyl-12-methylene-3,14-dioxa-tricyclo[9.3.0.0*2,4*]tetradec-7-en-13-one |
| (1aR,7aS,10aS,10bS,E)-1a,5- | dimethyl-8-methylene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[2',3':9,10]cyclodeca[1,2-b]furan-9(1aH)-one |
| (1aR,4E,7aS,10aS,10bS)-1a,5- | dimethyl-8-methylene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one |
| 4,5-alpha- | epoxy-6-beta-hydroxygermacra-1(10),11(13)-dien-12-oic acid gamma-lactone |
| (1aR,4E,7aS,10aS,10bS)-2,3,6,7,7a,8,10a,10b- | octahydro-1a,5-dimethyl-8-methylene oxireno(9,10)cyclodeca(1,2-b)furan-9(1ah)-one |
| [1aR-(1aR*,4E,7aS*,10aS*,-10bR*)]-2,3-6,7,7a,8,10a,10b- | octahydro-1a,5-dimethyl-8-methyleneoxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one |
| oxireno(9,10)cyclodeca(1,2-b)furan-9(1aH)-one, 2,3,6,7,7a,8,10a,10b-octahydro-1a,5-dimethyl-8-methylene-, (1aR,4E,7aS,10aS,10bS)- | |
| oxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one, 2,3,6,7,7a,8,10a,10b-octahydro-1a,5-dimethyl-8-methylene-, (1aR,4E,7aS,10aS,10bS)- |