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Category: natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Soluble in: |
| | water, 8408 mg/L @ 25 °C (est) |
Organoleptic Properties:
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | natural substances and extractives |
| Recommendation for N-acetyl histamine usage levels up to: | | | not for fragrance use.
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| Recommendation for N-acetyl histamine flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | acetamide, N-(2-(1H-imidazol-4-yl)ethyl)- (9CI) | | N-omega- | acetyl histamine | | N- | acetylhistamine | | N-(2-( | imidazol-4-yl)ethyl)acetamide | | N-[2-(1H- | imidazol-5-yl)ethyl]acetamide |
Articles:
| PubMed: | Metabolomics analysis of anaphylactoid reaction reveals its mechanism in a rat model. |
| PubMed: | [Active sites of N-acetylhexosamine 1-kinase from Bifidobacterium longum]. |
| PubMed: | Mechanistic and Structural Analysis of a Drosophila melanogaster Enzyme, Arylalkylamine N-Acetyltransferase Like 7, an Enzyme That Catalyzes the Formation of N-Acetylarylalkylamides and N-Acetylhistamine. |
| PubMed: | Algicidal metabolites produced by Bacillus sp. strain B1 against Phaeocystis globosa. |
| PubMed: | NaxD is a deacetylase required for lipid A modification and Francisella pathogenesis. |
| PubMed: | Transport of the anti-diabetic VO2+ complexes formed by pyrone derivatives in the blood serum. |
| PubMed: | Solution structure and acetyl-lysine binding activity of the GCN5 bromodomain. |
| PubMed: | Effects of intracerebroventricular administration of N-acetylhistamine on body temperature in mice. |
| PubMed: | Histamine: a neurotransmitter candidate for Drosophila photoreceptors. |
| PubMed: | Histidines, histamines and imidazoles as glycosidase inhibitors. |
| PubMed: | Histamine inhibition of mixed function oxidase activity in rat and human liver microsomes and in the isolated perfused rat liver. |
| PubMed: | Monooxygenation of N-acetylhistamine mediated by L-ascorbate. |
| PubMed: | Inhibition of in vivo histamine metabolism in rats by foodborne and pharmacologic inhibitors of diamine oxidase, histamine N-methyltransferase, and monoamine oxidase. |
| PubMed: | Properties of N-acetylhistamine deacetylase in mammalian brain. |
| PubMed: | [Molecular mechanism of the interaction of histamine with hyaluronic acid]. |
| PubMed: | Histamine receptors on human peripheral blood leucocytes. |
| PubMed: | [Oscillographic polarography of the alkaloid dolicotheline and several related imidazole derivatives]. |
| PubMed: | Model studies on the coordination of copper in biological systems. The deprotonated peptide nitrogen as a potential binding site for copper(II). |
| PubMed: | Elevation of histamine levels in rat and mouse tissues by the deacetylation of administered N-acetylhistamine. |
| PubMed: | The metabolism of exogenous histamine by aortic tissues. |
| PubMed: | Chemotactic activity of guinea pig eosinophils for the ECF-A acidic tetrapeptides, histamine, histamine metabolites, and the effect of H1- and H2-receptor antagonists. |
| PubMed: | Eosinophils and mediators of anaphylaxis. Histamine and imidazole acetic acid as chemotactic agents for human eosinophil leucocytes. |
| PubMed: | Partial purification and properties of N-acetylhistamine deacetylase. |
| PubMed: | New and uncommon indole- and imidazole-alkylamines in skins of amphibians from Australia and Papua New Guinea. |
| PubMed: | Effect of pharmacologic agents on human keratinocyte mitosis in vitro. III. Inhibition by histamine and methylated analogs. |
| PubMed: | Proceedings: Enzymatic deacetylation of N-acetylhistamine in the brain of rats. |
| PubMed: | Increased urinary imidazolepropionic acid, N-acetylhistamine and other imidazole compounds in patients with intestinal disorders. |
| PubMed: | Rupture of the imidazole ring of histamine and N-acetylhistamine by human intestinal contents. |
| PubMed: | Ionization of histamine, N-acetylhistamine, and their iodinated derivatives. |
| PubMed: | Iodinated derivatives of histamine and N-acetylhistamine. |
| PubMed: | Possible in vivo de-acetylation of N-acetylhistamine in man. |
| PubMed: | Fate of histamine and N-acetylhistamine administered into the human gut. |
| PubMed: | [Determination of histamine, N-dimethylhistamine, N-acetylhistamine and acetylcholine in Spinacia oleracea]. |
| PubMed: | A method of estimating histamine in plasma. |
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