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Category: cosmetic agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Melting Point: | 128.50 °C. @ 760.00 mm Hg
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| Boiling Point: | 490.40 °C. @ 760.00 mm Hg (est)
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| Flash Point: | 485.00 °F. TCC ( 251.60 °C. ) (est)
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| logP (o/w): | -3.370 (est) |
| Soluble in: |
| | water, 5.00E+05 mg/L @ 25 °C (exp) | | | water, 1e+006 mg/L @ 25 °C (est) |
Organoleptic Properties:
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | cosmetic agents |
| Recommendation for meglumine usage levels up to: | | | not for fragrance use.
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| Recommendation for meglumine flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
| | (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 6284-40-8 |
| Pubchem (cid): | 8567 |
| Pubchem (sid): | 134986908 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 1- | deoxy-1-(methylamino)-D-glucitol | | 1- | deoxy-1-methylaminosorbitol | | D- | glucitol, 1-deoxy-1-(methylamino)- | | | glucitol, 1-deoxy-1-(methylamino)-, D- (8CI) | | | iosulamide | | | meglumin | | | meglumina | | | megluminum | | | methyl glucamine | | N- | methyl-D-glucamine | | N- | methyl-D(-)-glucamine | | N- | methyl-dextro-glucamine | | (2R,3R,4R,5S)-6-( | methylamino)hexane-1,2,3,4,5-pentol | | | methylglucamine | | D-(-)-N- | methylglucamine | | N- | methylglucamine | | N- | methylglucamine solution | | N- | methylsorbitylamine | | | sorbitol, 1-deoxy-1-methylamino- |
Articles:
| PubMed: | Pain sensitivity and healing of hot-iron cattle brands. |
| PubMed: | Healing of surgical castration wounds: a description and an evaluation of flunixin. |
| PubMed: | The effect of breed and sex on sulfamethazine, enrofloxacin, fenbendazole and flunixin meglumine pharmacokinetic parameters in swine. |
| PubMed: | Silibinin meglumine, a water-soluble form of milk thistle silymarin, is an orally active anti-cancer agent that impedes the epithelial-to-mesenchymal transition (EMT) in EGFR-mutant non-small-cell lung carcinoma cells. |
| PubMed: | Gd(3+)-DTPA-Meglumine-Anionic Linear Globular Dendrimer G1: Novel Nanosized Low Toxic Tumor Molecular MR Imaging Agent. |
| PubMed: | The CCKB antagonist CI988 reduces food intake in fasted rats via a dopamine mediated pathway. |
| PubMed: | Examining the occurrence of residues of flunixin meglumine in cull dairy cows by use of the flunixin cull cow survey. |
| PubMed: | Tafamidis for transthyretin amyloidosis. |
| PubMed: | Roux-en-Y gastric bypass in mice--surgical technique and characterisation. |
| PubMed: | Taeniasis and cysticercosis due to Taenia solium in Japan. |
| PubMed: | Associations among behavioral and acute physiologic responses to lipopolysaccharide-induced clinical mastitis in lactating dairy cows. |
| PubMed: | Effects of buprenorphine, meloxicam, and flunixin meglumine as postoperative analgesia in mice. |
| PubMed: | [Simultaneous analysis of 4 non-steroidal anti-inflammatory drug residues in mutton muscle using high performance liquid chromatography assisted by ultrasonic-microwave extraction]. |
| PubMed: | Signal quality of single dose gadobenate dimeglumine pulmonary MRA examinations exceeds quality of MRA performed with double dose gadopentetate dimeglumine. |
| PubMed: | Incidence of immediate gadolinium contrast media reactions. |
| PubMed: | Biomarkers of inflammation in cattle determining the effectiveness of anti-inflammatory drugs. |
| PubMed: | Phosphine intoxication following oral exposure of horses to aluminum phosphide-treated feed. |
| PubMed: | Pain mitigation after band castration of beef calves and its effects on performance, behavior, Escherichia coli, and salivary cortisol. |
| PubMed: | Treatment of calf diarrhea: antimicrobial and ancillary treatments. |
| PubMed: | A physiologically based pharmacokinetic model linking plasma protein binding interactions with drug disposition. |
| PubMed: | Extralabel use of nonsteroidal anti-inflammatory drugs in cattle. |
| PubMed: | [The Grenelle of MR contrast agents?]. |
| PubMed: | Response to the FDA's May 23, 2007, nephrogenic systemic fibrosis update. |
| PubMed: | FDA issues reminder on correct use of flunixin meglumine. |
| PubMed: | Surveillance for selected bacterial and toxicologic contaminants in donated carcass meat fed to carnivores. |
| PubMed: | Pharmacokinetics of flunixin meglumine in swine after intravenous dosing. |
| PubMed: | A woman who excreted a tape-like substance. Diphyllobothriasis. |
| PubMed: | Evaluating postoperative analgesics in mice using telemetry. |
| PubMed: | Residue depletion study and withdrawal period for flunixin-N-methyl glucamine in bovine milk following intravenous administration. |
| PubMed: | Flunixin residues in milk after intravenous treatment of dairy cattle with (14)C-flunixin. |
| PubMed: | Transcervical catheterization and cervical patency during the oestrous cycle in domestic cats. |
| PubMed: | Successful treatment of drug-resistant cutaneous leishmaniasis in humans by use of imiquimod, an immunomodulator. |
| PubMed: | A simple method for the identification and assay of iopamidol and iothalamate meglumine in pharmaceutical samples based on proton nuclear magnetic resonance spectroscopy. |
| PubMed: | Review of studies establishing the aging male spontaneously hypertensive rat as a detector and quantifier of the kidney toxicity of radiocontrast media and other chemicals. |
| PubMed: | [Reproductive and developmental toxicity study of gadobenate dimeglumine formulation (E7155) (3)--Study of embryo-fetal toxicity in rabbits by intravenous administration]. |
| PubMed: | [Reproductive and developmental toxicity study of gadobenate dimeglumine formulation (E7155) (2)--Combined study of effects on fertility and embryo-fetal toxicity in female rats by intravenous administration]. |
| PubMed: | [Reproductive and developmental toxicity study of gadobenate dimeglumine formulation (E7155) (1)--Fertility study in male rats by intravenous administration]. |
| PubMed: | [General toxicity study of gadobenate dimeglumine formulation (E7155) (4)--4-week repeated dose intravenous toxicity study followed by 4-week recovery period in dogs]. |
| PubMed: | [General toxicity study of gadobenate dimeglumine formulation (E7155) (2)--Single dose intravenous toxicity study in dogs]. |
| PubMed: | Clinical follow-up examination after treatment of canine leishmaniasis. |
| PubMed: | Drug disposition and dosage determination of once daily administration of gentamicin sulfate in horses after abdominal surgery. |
| PubMed: | Effects of radiocontrast, mannitol, and endothelin on blood pressure and renal damage in the aging male spontaneously hypertensive rat. |
| PubMed: | Inhibition of gastrin-stimulated cell proliferation by the CCK-B/gastrin receptor ligand CI-988. |
| PubMed: | CholecystokininB receptor antagonist increases food intake in rats. |
| PubMed: | Fatal adverse event secondary to high osmolality contrast agent. |
| PubMed: | Effects of radiocontrast and endothelin administration on systolic blood pressure and renal damage in male spontaneously hypertensive and Wistar Kyoto rats with phentolamine-induced adrenergic blockade. |
| PubMed: | Gastric effects of the CCK-B/gastrin receptor ligand CI-988 in cynomolgus monkeys. |
| PubMed: | The SHR as a small animal model for radiocontrast renal failure. Relation of nephrotoxicity to animal's age, gender, strain, and dose of radiocontrast. |
| PubMed: | Ancillary therapy of bovine respiratory disease. |
| PubMed: | Extralabel use of nonsteroidal anti-inflammatory drugs. |
| PubMed: | Failure of dietary bentonite clay, Silent Herder mineral supplement, or parenteral Banamine to alleviate locoweed toxicosis in rats. |
| PubMed: | Effect of portal venous flow augmentation on liver enhancement with CT. |
| PubMed: | Effects of a liquid meal on contrast-enhanced CT of the liver. |
| PubMed: | Cholecystokinin A receptor antagonist inhibits feed memory in Japanese quail. |
| PubMed: | Simple 1H NMR spectroscopic method for assay of salts of the contrast agent diatrizoate in commercial solutions. |
| PubMed: | PD-135158, a CCKB receptor antagonist, microinjected into the nucleus accumbens and the expression of conditioned rewarded behavior. |
| PubMed: | Determination of flunixin in milk by liquid chromatography with confirmation by gas chromatography/mass spectrometry and selected ion monitoring. |
| PubMed: | Approval from the Food and Drug Administration for unapproved use of an approved drug or device. |
| PubMed: | [Relationship between oral food intake and nausea caused by intravenous injection of iodinated contrast material]. |
| PubMed: | Esophageal perforation in recessive dystrophic epidermolysis bullosa. |
| PubMed: | Effects of cholecystokinin antagonists on the discriminative stimulus effects of cocaine in rats and monkeys. |
| PubMed: | Use of nonsteroidal anti-inflammatory drugs in food animal practice. |
| PubMed: | Inhibition of food intake by omeprazole in the chicken. |
| PubMed: | Treatment of diarrhea of neonatal calves. |
| PubMed: | Evaluation of the effects of PD 134308 (CI-988), a CCK-B antagonist, on the punished responding of squirrel monkeys. |
| PubMed: | The influence of anti-inflammatory therapy on bacterial clearance following intramammary Escherichia coli challenge in goats. |
| PubMed: | Pharmacokinetics of flunixin meglumine in lactating cattle after single and multiple intramuscular and intravenous administrations. |
| PubMed: | Gadopentetate dimeglumine: observations on the clinical research process. |
| PubMed: | Opening of the blood-brain barrier by intravenous contrast media in euvolemic and dehydrated rabbits. |
| PubMed: | Castor-oil induced diarrhoea in ponies: a model for acute colitis. |
| PubMed: | Anti-inflammatory therapy in acute endotoxin-induced bovine mastitis. |
| PubMed: | Experimental uses of flunixin meglumine and phenylbutazone in food-producing animals. |
| PubMed: | Cardiovascular responses to the intravertebral artery injection of hypertonic contrast media in the dog. |
| PubMed: | Avoidance reaction of painful stimulation of another rat: effect of methylglucamine orotate. |
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