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Category: flavor enhancers, humectants, carriers, sweeteners
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | white crystalline powder (est) |
| Assay: | 99.00 to 100.00 %
|
| Food Chemicals Codex Listed: | No |
| Melting Point: | 119.00 to 123.00 °C. @ 760.00 mm Hg
|
| Boiling Point: | 330.00 to 331.00 °C. @ 760.00 mm Hg
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| Flash Point: | 408.00 °F. TCC ( 208.70 °C. ) (est)
|
| logP (o/w): | -2.996 (est) |
| Soluble in: |
| | water, 6.10E+05 mg/L @ 22 °C (exp) | | | alcohol, slightly |
| Insoluble in: |
| | diethyl ether |
Organoleptic Properties:
Odor Description: at 100.00 %. | odorless |
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
| American International Chemical, LLC. |
| ERYTHRITOL FCC
|
| Atlantic Chemicals |
| Erythritol
|
| BOC Sciences |
| For experimental / research use only. |
| meso-Erythritol
|
| Carbosynth |
| For experimental / research use only. |
| meso-Erythritol
|
| Cargill, Inc. |
| Zerose® erythritol
Flavor: characteristic Erythritol, a natural, zero calorie, high digestive tolerance polyol, provides bulk, texture, high cooling effect and preservative benefits of sucrose in sugar-free and calorie-reduced products. Erythritol is suitable for dental health, weight management and sugar avoiders. |
| Coompo |
| For experimental / research use only. |
| Erythritol from Plants ≥96%
|
| ECSA Chemicals |
| ERYTHRITOL
|
| ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY |
| ExtraSynthese |
| For experimental / research use only. |
| meso-Erythritol
|
| Foodchem International |
| Erythritol
|
| Glentham Life Sciences |
| meso-Erythritol
|
| Jiangyin Healthway |
| Erythritol
|
| New functional food ingredients |
| Jungbunzlauer Suisse |
| ERYLITE®
Flavor: sweet ERYLITE® is a novel bulk sweetener with a caloric value close to zero. Chemically, it is a four-carbon sugar alcohol (polyol). ERYLITE® is produced by microbial fermentation of a carbohydrate substrate. It is the only all-natural sugar alcohol available today. |
| Kraft Chemical |
| Erythritol
|
| O'Laughlin Industries |
| Erythritol /Stevia agglomerated blend
10 to 1 sugar sweetness |
| O'Laughlin Industries |
| Erythritol /Stevia agglomerated blend
5 to 1 sugar sweetness |
| O'Laughlin Industries |
| Erythritol, FCC
|
| O'Laughlin Industries |
| ERYTHRITOL/ STEVIA CO-CRYSTALLIZED BLEND
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| O'Laughlin Industries |
| ERYTHRITOL/ STEVIA CO-CRYSTALLIZED BLEND
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| Penta International |
| meso-ERYTHRITOL
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| Prinova |
| Erythritol FCC
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| Santa Cruz Biotechnology |
| For experimental / research use only. |
| meso-Erythritol ≥98%
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| Sigma-Aldrich: Sigma |
| For experimental / research use only. |
| meso-Erythritol ≥99%
|
| Sinofi Food Ingredients |
| Erythritol
Flavor: characteristic Sugar Substitutes, Chewing Gum, Beverages, Confections, Baking Food, Chocolate, Instant Coffee, Ice Cream. |
| TCI AMERICA |
| For experimental / research use only. |
| meso-Erythritol >99.0%(HPLC)(T)
|
| United International |
| Erythritol
|
| Viachem |
| Erythritol
Odor: bland Use: Erythritol, C4H10O4, is a novel bulk sweetener with a caloric value close to zero. Chemically, it is a four-carbon sugar alcohol (polyol). Erythritol, a white crystalline powder, is made through fermentation. |
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
intraperitoneal-mouse LD50 7000 mg/kg Proceedings of the Society for Experimental Biology and Medicine. Vol. 35, Pg. 98, 1936.
intravenous-dog LDLo 5000 mg/kg "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989Vol. 11, Pg. 576, 1989.
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| Dermal Toxicity: |
|
Not determined
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| Inhalation Toxicity: |
|
Not determined
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Safety in Use Information:
| Category: | flavor enhancers, humectants, carriers, sweeteners |
| Recommendation for meso-erythritol usage levels up to: | | | not for fragrance use.
|
| |
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
| publication number: 28. Update in publication number(s): 29 |
| Click here to view publication 28 |
| | average usual ppm | average maximum ppm |
| baked goods: | - | - |
| beverages(nonalcoholic): | 5000.00000 | 12500.00000 |
| beverages(alcoholic): | 5000.00000 | 12500.00000 |
| breakfast cereal: | 12500.00000 | 17500.00000 |
| cheese: | - | - |
| chewing gum: | - | - |
| condiments / relishes: | - | - |
| confectionery froastings: | - | - |
| egg products: | - | - |
| fats / oils: | - | - |
| fish products: | - | - |
| frozen dairy: | 12500.00000 | 17500.00000 |
| fruit ices: | 5000.00000 | 12500.00000 |
| gelatins / puddings: | - | - |
| granulated sugar: | - | - |
| gravies: | - | - |
| hard candy: | - | - |
| imitation dairy: | 12500.00000 | 17500.00000 |
| instant coffee / tea: | 5000.00000 | 12500.00000 |
| jams / jellies: | - | - |
| meat products: | - | - |
| milk products: | 12500.00000 | 17500.00000 |
| nut products: | 12500.00000 | 17500.00000 |
| other grains: | 12500.00000 | 17500.00000 |
| poultry: | - | - |
| processed fruits: | 5000.00000 | 12500.00000 |
| processed vegetables: | - | - |
| reconstituted vegetables: | - | - |
| seasonings / flavors: | - | - |
| snack foods: | - | - |
| soft candy: | - | - |
| soups: | - | - |
| sugar substitutes: | - | - |
| sweet sauces: | - | - |
Safety References:
| European Food Safety Authority (EFSA) reference(s): |
Statement in relation to the safety of erythritol (E 968) in light of new data, including a new paediatric study on the gastrointestinal tolerability of erythritol View page or View pdf |
ment on a refined dietary exposure assessment of erythritol (E 968) taking into account additional data provided View page or View pdf |
Scientific Opinion on the safety of the proposed extension of use of erythritol (E 968) as a food additive View page or View pdf |
Sugar-free hard confectionery with at least 90% erythritol and reduction of dental plaque which reduces the risk of dental caries: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006 View page or View pdf |
Outcome of the public consultation on a draft protocol for assessing exposure to sweeteners as part of their safety assessment under the food additives re-evaluation programme View page or View pdf |
| EPI System: | View |
| ClinicalTrials.gov: | search |
| Daily Med: | search |
| Chemical Carcinogenesis Research Information System: | Search |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA Substance Registry Services (TSCA): | 149-32-6 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 222285 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 3 |
| | (2R,3S)-butane-1,2,3,4-tetrol |
| Chemidplus: | 0000149326 |
| RTECS: | KF2000000 for cas# 149-32-6 |
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | antierythrite | | (R*,S*)-1,2,3,4- | butane tetrol | | (2R,3S)- | butane-1,2,3,4-tetraol | | (2R,3S)- | butane-1,2,3,4-tetrol | | meso- | butane-1,2,3,4-tetrol | | (2R,3S)-1,2,3,4- | butanetetrol | | (R*,R*)-1,2,3,4- | butanetetrol | | DL-1,2,3,4- | butanetetrol | | 1,2,3,4- | butanetetrol, (2R,3S)- | | (2R,3S)-1,2,3,4- | butantetrol | | | erythrite | | (R*,S*)- | tetrahydroxybutane | | DL- | threitol |
Articles:
| PubMed: | Amplification of Hofmeister Effect by Alcohols. |
| PubMed: | Recognition of riboflavin and the capsular polysaccharide of Haemophilus influenzae type b by antibodies generated to the haptenic epitope D-ribitol. |
| PubMed: | Gluconobacter cerevisiae sp. nov., isolated from the brewery environment. |
| PubMed: | Flow of suspensions of carbon nanotubes carrying phase change materials through microchannels and heat transfer enhancement. |
| PubMed: | Chemical constituents from Glyphaea brevis and Monodora myristica: chemotaxonomic significance. |
| PubMed: | [Simultaneous determination of meso-erythritol and L-erythrulose in fermentation broth using high performance liquid chromatography]. |
| PubMed: | Enzymatic synthesis of novel branched sugar alcohols mediated by the transglycosylation reaction of pullulan-hydrolyzing amylase II (TVA II) cloned from Thermoactinomyces vulgaris R-47. |
| PubMed: | Characterization and inactivation of the membrane-bound polyol dehydrogenase in Gluconobacter oxydans DSM 7145 reveals a role in meso-erythritol oxidation. |
| PubMed: | Reactivity of poly-alcohols towards OH, NO3 and SO4- in aqueous solution. |
| PubMed: | Nonviral vectors with a biosurfactant MEL-A promote gene transfection into solid tumors in the mouse abdominal cavity. |
| PubMed: | Gluconobacter sphaericus (Ameyama 1975) comb. nov., a brown pigment-producing acetic acid bacterium in the Alphaproteobacteria. |
| PubMed: | Analysis of erythritol in foods by polyclonal antibody-based indirect competitive ELISA. |
| PubMed: | Production of different types of mannosylerythritol lipids as biosurfactants by the newly isolated yeast strains belonging to the genus Pseudozyma. |
| PubMed: | Characterization of the genus Pseudozyma by the formation of glycolipid biosurfactants, mannosylerythritol lipids. |
| PubMed: | Interstrand and intrastrand DNA-DNA cross-linking by 1,2,3,4-diepoxybutane: role of stereochemistry. |
| PubMed: | Anaphylaxis to excipient mannitol: evidence for an immunoglobulin E-mediated mechanism. |
| PubMed: | Pseudonocardia antarctica sp. nov. an Actinomycetes from McMurdo Dry Valleys, Antarctica. |
| PubMed: | Determination of glycerol by gas chromatography using meso-erythritol as internal standard. |
| PubMed: | Biosurfactant MEL-A dramatically increases gene transfection via membrane fusion. |
| PubMed: | Herbaspirillum lusitanum sp. nov., a novel nitrogen-fixing bacterium associated with root nodules of Phaseolus vulgaris. |
| PubMed: | Use of DSC to detect the heterogeneity of hydrothermal stability in the polyphenol-treated collagen matrix. |
| PubMed: | New quinoproteins in oxidative fermentation. |
| PubMed: | New developments in oxidative fermentation. |
| PubMed: | Pseudomonas grimontii sp. nov. |
| PubMed: | Modeling and measurements of solid-liquid and vapor-liquid equilibria of polyols and carbohydrates in aqueous solution. |
| PubMed: | L-erythrulose production by oxidative fermentation is catalyzed by PQQ-containing membrane-bound dehydrogenase. |
| PubMed: | Isolation of yeast Kurtzmanomyces sp. I-11, novel producer of mannosylerythritol lipid. |
| PubMed: | Membrane-bound quinoprotein D-arabitol dehydrogenase of Gluconobacter suboxydans IFO 3257: a versatile enzyme for the oxidative fermentation of various ketoses. |
| PubMed: | Phenotypic characterization of Microsporum canis isolated from cats and dogs. |
| PubMed: | Herbaspirillum frisingense sp. nov., a new nitrogen-fixing bacterial species that occurs in C4-fibre plants. |
| PubMed: | Determination of sugar alcohols in confectioneries by high-performance liquid chromatography after nitrobenzoylation. |
| PubMed: | Characterization of a biosurfactant, mannosylerythritol lipid produced from Candida sp. SY16. |
| PubMed: | Pseudomonas gessardii sp. nov. and Pseudomonas migulae sp. nov., two new species isolated from natural mineral waters. |
| PubMed: | At physiological expression levels the Kidd blood group/urea transporter protein is not a water channel. |
| PubMed: | Liquid chromatographic determination of sugar alcohols in beverages and foods after nitrobenzoylation. |
| PubMed: | Emended description of Herbaspirillum; inclusion of [Pseudomonas] rubrisubalbicans, a milk plant pathogen, as Herbaspirillum rubrisubalbicans comb. nov.; and classification of a group of clinical isolates (EF group 1) as Herbaspirillum species 3. |
| PubMed: | Nutritional physiology and taxonomy of human-pathogenic Cladosporium-Xylohypha species. |
| PubMed: | Evidence for a glycerol pathway through aquaporin 1 (CHIP28) channels. |
| PubMed: | Nutritional physiology and selective isolation of Exophiala dermatitidis. |
| PubMed: | Possibility of allergic reaction to dentin primer--application on the skin of guinea pigs. |
| PubMed: | Bonding efficacy of erythritol methacrylate solutions as dentin primers. |
| PubMed: | Volumetric properties of polyols (ethylene glycol, glycerol, meso-erythritol, xylitol and mannitol) in relation to their membrane permeability: group additivity and estimation of the maximum radius of their molecules. |
| PubMed: | Usefulness of trehalose fermentation and L-glutamic acid decarboxylation for identification of biochemically aberrant Providencia stuartii strains. |
| PubMed: | The use of meso-erythritol sensitivity discs in the typing of Brucella strains. |
| PubMed: | [Determination of biovars of Brucella melitensis by manometric character: epidemiological value and relation to serovars]. |
| PubMed: | Osmotic deformation of red blood cell ghosts induced by carbohydrates. |
| PubMed: | Effect of intracytoplasmic membrane development on oxidation of sorbitol and other polyols by Gluconobacter oxydans. |
| PubMed: | Biotypes of Proteus rettgeri. |
| PubMed: | Investigations with 1,4-bis-(2'-mesyloxyethylamino)-1,4-dideoxy-meso-erythritol (R-74). |
| PubMed: | IDENTIFICATION OF ALTRO-HEPTULOSE AND L-THREITOL AS PRODUCTS OF MESO-ERYTHRITOL OXIDATION BY ACETOBACTER SUBOXYDANS. |
| PubMed: | A note on meso-erythritol, a metabolic product of Aspergillus terreus. |
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