|
Category: cosmetic agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | colorless to pale yellow clear liquid (est) |
| Assay: | 95.00 to 100.00 %
|
| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 1.32500 @ 25.00 °C.
|
| Melting Point: | -16.50 °C. @ 760.00 mm Hg (est)
|
| Boiling Point: | 225.48 °C. @ 760.00 mm Hg (est)
|
| Vapor Pressure: | 0.031000 mmHg @ 25.00 °C. (est) |
| Vapor Density: | 3.18 ( Air = 1 ) |
| Flash Point: | > 230.00 °F. TCC ( > 110.00 °C. )
|
| logP (o/w): | 0.090 |
| Soluble in: |
| | water, 1.00E+06 mg/L @ 25 °C (exp) | | | water, 2.558e+005 mg/L @ 25 °C (est) |
Organoleptic Properties:
| |
| Odor and/or flavor descriptions from others (if found). |
| |
| |
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
intraperitoneal-guinea pig LD50 157 mg/kg Zeitschrift fuer die Gesamte Hygiene und Ihre Grenzgebiete. Vol. 20, Pg. 575, 1974.
oral-guinea pig LD50 126 mg/kg "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 586, 1969.
oral-mammal (species unspecified) LD50 250 mg/kg Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 39(4), Pg. 86, 1974.
intraperitoneal-mouse LD50 138 mg/kg Arzneimittel-Forschung. Drug Research. Vol. 31, Pg. 1713, 1981.
intravenous-mouse LD50 145 mg/kg Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 60, Pg. 278, 1964.
oral-mouse LD50 242 mg/kg Zeitschrift fuer die Gesamte Hygiene und Ihre Grenzgebiete. Vol. 20, Pg. 575, 1974.
intravenous-rabbit LD50 100 mg/kg Biochemical Journal. Vol. 41, Pg. 325, 1947.
oral-rabbit LD50 119 mg/kg Zeitschrift fuer die Gesamte Hygiene und Ihre Grenzgebiete. Vol. 20, Pg. 575, 1974.
intraperitoneal-rat LD50 70 mg/kg Zeitschrift fuer die Gesamte Hygiene und Ihre Grenzgebiete. Vol. 20, Pg. 575, 1974.
oral-rat LD50 114 mg/kg Zeitschrift fuer die Gesamte Hygiene und Ihre Grenzgebiete. Vol. 20, Pg. 575, 1974.
|
| Dermal Toxicity: |
skin-mouse LD50 47 mg/kg BEHAVIORAL: TREMOR
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Science Reports of the Research Institutes, Tohoku University, Series C: Medicine. Vol. 36(1-4), Pg. 10, 1989.
skin-rabbit LDLo 300 mg/kg SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 13(1), Pg. 48, 1969.
|
| Inhalation Toxicity: |
inhalation-mouse LCLo 7 mg/m3/2H "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 111, 1982.
inhalation-rat LC50 210 mg/m3/4H LUNGS, THORAX, OR RESPIRATION: CHANGES IN LUNG WEIGHT
LUNGS, THORAX, OR RESPIRATION: DYSPNEA
BEHAVIORAL: FOOD INTAKE (ANIMAL) National Technical Information Service. Vol. OTS0554077
|
Safety in Use Information:
| Category: | cosmetic agents |
| Recommendation for thioglycolic acid usage levels up to: | | | not for fragrance use.
|
| |
| Recommendation for thioglycolic acid flavor usage levels up to: |
| | not for flavor use.
|
Safety References:
References:
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| CHEBI: | View |
| CHEMBL: | View |
| KEGG (GenomeNet): | C02086 |
| HMDB (The Human Metabolome Database): | Search |
| Export Tariff Code: | 2930.90.4910 |
| ChemSpider: | View |
| Wikipedia: | View |
Formulations/Preparations: •in widely avail commercial cold-wave prepn for waving hair there is as a rule no free thioglycolic acid. instead these prepn contain ammonium, sodium, or calcium thioglycolate at mildly alkaline ph, commonly ph 9.5 & are far less dangerous to the eye than is free thioglycolic acid.
•commercial forms of mercaptoacetic acid are the 99% acid and the 80% acid.
•available commercially as an anhydrous powder or an aqueous solution containing 70-80% active matter.
•thioglycolic acid is marketed as pure product or at 80-85% wt% aqueous solution.
|
Potential Blenders and core components note
Potential Uses:
| | depilating agents | |
| | reducing agents | |
Occurrence (nature, food, other): note
Synonyms:
| | acetic acid, 2-mercapto- | | | acetic acid, mercapto- | | | glycolic acid, 2-thio- | | | glycolic acid, thio- | | | mercaptoacetic acid | | 2- | mercaptoacetic acid | | alpha- | mercaptoacetic acid | | | mercaptoethanoic acid | | 2- | mercaptoethanoic acid | | | sulfanylacetic acid | | 2- | sulfanylacetic acid | | 2- | thioglycolic acid | | | thioglycolic acid- | | | thioglycollic acid | | | thiovanic acid |
Articles:
|