thioglycolic acid
acetic acid, mercapto-
 
Notes:
None found
  • ECSA Chemicals
    • ECSA Chemicals
      Human Chemistry
      ECSA Chemicals has been active since 1913 in the trading and international commerce of raw materials. With an organisation divided into industrial segments managed by specialists, it has become one of the largest distributors worldwide.
      ECSA Chemicals is the largest Swiss-owned company in terms of warehouses for the distribution of chemical products. We have been distributing chemical products for over 100 years and we have a special interest in protecting the environment and in the safety of our facilities and collaborators.
      Established in 1913 as a small grocery store, in its over 100 years of activity ECSA Chemicals has become one of the most important Swiss-owned distributors of chemical products. The company, which is active in international distribution and trading, is organised into industrial segments that are managed by teams of specialists and experts. They guarantee professional and customised consultancy and services. With our experience, we can rapidly and safely connect you with the best suppliers on the market, providing you with a complete search, consulting and assistance service. The focus of our approach and operations is you, our customers. We strive every day to find the best products that satisfy your needs as quickly as possible. Your satisfaction is our greatest success. WHY CHOOSE ECSA? EXPERIENCE We have been working for 100 years. QUALITY We have obtained many certifications (ISO, SQAS, GDP, Responsible Care, Bio-Inspecta, RSPO, etc.). We guarantee full compliance with the current laws and continuous training for our staff. SAFETY We constantly carry out risk analyses for each infrastructure, defining safety levels and implementing corrective measures promptly wherever they are needed. WIDESPREAD DISTRIBUTION We have warehouses in strategic locations to supply goods to Switzerland and to the rest of the world. STORAGE CAPACITY The 3 ECSA-owned warehouses guarantee considerable storage area and capacity in each warehouse, with full availability of products (base chemicals and speciality chemicals). SPEED Presence all over the country, staff dedicated to sourcing raw materials and considerable storage capacity guarantee that goods are rapidly obtained and supplied. CONSULTANCY Our specialists - in-depth knowledge of the market and products allows us to provide full consulting services, from the purchase to the supply of raw materials.
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      ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY
      Products List: View
      Product(s):
      RE-411385 THIOGLYCOLIC ACID 80% RPE-FOR ANALYSIS, ML 5
       
  • Glentham Life Sciences
  • Penta International
    • Penta International Corporation
      Chemistry innovation
      At Penta, our products and services help businesses do business better.
      For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes.
      US Email: Technical Services
      US Email: Sales
      US Voice: (973) 740-2300
      US Fax: (973) 740-1839
      Product(s):
      13-15400 MERCAPTOACETIC ACID
       
  • TCI AMERICA
    • TCI AMERICA
      Moving Your Chemistry Forward
      We continuously strive to advance our technology.
      With East & West Coast distribution centers, count on TCI to deliver products quickly and reliably. Over 30,000 Reagents available today in benchtop to bulk quantities. We also offer custom synthesis solutions. Sign up for a TCI account today for fast and free shipping!
      Tokyo Chemical Industry Co., Ltd. (TCI) is a leading worldwide manufacturer of specialty organic chemicals founded in 1946. TCI provides organic laboratory chemicals as well as pharmaceutical, cosmetic and functional materials. More than 70 years of synthesis experience and multi-purpose plants enable TCI to offer more than 30,000 products as well as custom synthesis.
      US Email: Sales
      Email: Technical Support
      Voice: 1-800-423-8616
      Fax: 1- 888-520-1075
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      Product(s):
      M0052 Thioglycolic Acid >98.0%(T)
       
Synonyms   Articles   Notes   Search
CAS Number: 68-11-1Picture of molecule3D/inchi
Other(deleted CASRN): 57755-20-1
ECHA EINECS - REACH Pre-Reg: 200-677-4
FDA UNII: 7857H94KHM
Nikkaji Web: J4.856I
Beilstein Number: 0506166
MDL: MFCD00004876
XlogP3: 0.10 (est)
Molecular Weight: 92.11728000
Formula: C2 H4 O2 S
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome or firefox)
Category: cosmetic agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
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Physical Properties:
Appearance: colorless to pale yellow clear liquid (est)
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Specific Gravity: 1.32500 @  25.00 °C.
Melting Point: -16.50 °C. @ 760.00 mm Hg (est)
Boiling Point: 225.48 °C. @ 760.00 mm Hg (est)
Vapor Pressure: 0.031000 mmHg @ 25.00 °C. (est)
Vapor Density: 3.18 ( Air = 1 )
Flash Point: > 230.00 °F. TCC ( > 110.00 °C. )
logP (o/w): 0.090
Soluble in:
 water, 1.00E+06 mg/L @ 25 °C (exp)
 water, 2.558e+005 mg/L @ 25 °C (est)
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: antioxidants
depilatories
hair straightening agents
hair waving agents
reducing agents
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Suppliers:
Arkema
TGA
Odor: characteristic
Use: Thioglycolic acid forms powerful complexes with metals that gives it specific characteristics sought after for the assisted recovery of ore as well as for cleaning and corrosion inhibition.
BRUNO BOCK
Thioglycolic Acid
Odor: characteristic
Use: TGA's unique reducing properties make it an ideal candidate for a wide variety of chemical reactions including addition, elimination, or cyclization reactions. TGA's thiol group (-SH) will react in the presence of bases, acids, ketone groups or organic halogens. In the presence of alcohols or amines, the carboxylic group will react preferentially.
ECSA Chemicals
THIOGLYCOLIC ACID 80% RPE-FOR ANALYSIS, ML 5
ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY
EMD Millipore
For experimental / research use only.
Thioglycolic Acid
Glentham Life Sciences
Thioglycolic acid
Penta International
MERCAPTOACETIC ACID
Santa Cruz Biotechnology
For experimental / research use only.
Thioglycolic acid
Sigma-Aldrich
For experimental / research use only.
Thioglycolic acid ≥98%
TCI AMERICA
For experimental / research use only.
Thioglycolic Acid >98.0%(T)
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Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-guinea pig LD50  157 mg/kg
Zeitschrift fuer die Gesamte Hygiene und Ihre Grenzgebiete. Vol. 20, Pg. 575, 1974.

oral-guinea pig LD50  126 mg/kg
"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 586, 1969.

oral-mammal (species unspecified) LD50  250 mg/kg
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 39(4), Pg. 86, 1974.

intraperitoneal-mouse LD50  138 mg/kg
Arzneimittel-Forschung. Drug Research. Vol. 31, Pg. 1713, 1981.

intravenous-mouse LD50  145 mg/kg
Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 60, Pg. 278, 1964.

oral-mouse LD50  242 mg/kg
Zeitschrift fuer die Gesamte Hygiene und Ihre Grenzgebiete. Vol. 20, Pg. 575, 1974.

intravenous-rabbit LD50  100 mg/kg
Biochemical Journal. Vol. 41, Pg. 325, 1947.

oral-rabbit LD50  119 mg/kg
Zeitschrift fuer die Gesamte Hygiene und Ihre Grenzgebiete. Vol. 20, Pg. 575, 1974.

intraperitoneal-rat LD50  70 mg/kg
Zeitschrift fuer die Gesamte Hygiene und Ihre Grenzgebiete. Vol. 20, Pg. 575, 1974.

oral-rat LD50  114 mg/kg
Zeitschrift fuer die Gesamte Hygiene und Ihre Grenzgebiete. Vol. 20, Pg. 575, 1974.

Dermal Toxicity:
skin-mouse LD50 47 mg/kg
BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Science Reports of the Research Institutes, Tohoku University, Series C: Medicine. Vol. 36(1-4), Pg. 10, 1989.

skin-rabbit LDLo 300 mg/kg
SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 13(1), Pg. 48, 1969.

Inhalation Toxicity:
inhalation-mouse LCLo 7 mg/m3/2H
"Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 111, 1982.

inhalation-rat LC50 210 mg/m3/4H
LUNGS, THORAX, OR RESPIRATION: CHANGES IN LUNG WEIGHT LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: FOOD INTAKE (ANIMAL)
National Technical Information Service. Vol. OTS0554077

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Safety in Use Information:
Category: cosmetic agents
Recommendation for thioglycolic acid usage levels up to:
 not for fragrance use.
 
Recommendation for thioglycolic acid flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
NIOSH International Chemical Safety Cards: search
NIOSH Pocket Guide: search
Chemical Carcinogenesis Research Information System: Search
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA Substance Registry Services (TSCA): 68-11-1
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 1133
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 1
 2-sulfanylacetic acid
Chemidplus: 0000068111
EPA/NOAA CAMEO: hazardous materials
RTECS: 68-11-1
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References:
 2-sulfanylacetic acid
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 68-11-1
Pubchem (cid): 1133
Pubchem (sid): 134971045
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEBI: View
CHEMBL: View
KEGG (GenomeNet): C02086
HMDB (The Human Metabolome Database): Search
Export Tariff Code: 2930.90.4910
ChemSpider: View
Wikipedia: View
Formulations/Preparations:
•in widely avail commercial cold-wave prepn for waving hair there is as a rule no free thioglycolic acid. instead these prepn contain ammonium, sodium, or calcium thioglycolate at mildly alkaline ph, commonly ph 9.5 & are far less dangerous to the eye than is free thioglycolic acid. •commercial forms of mercaptoacetic acid are the 99% acid and the 80% acid. •available commercially as an anhydrous powder or an aqueous solution containing 70-80% active matter. •thioglycolic acid is marketed as pure product or at 80-85% wt% aqueous solution.
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
 depilating agents 
 reducing agents 
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
 acetic acid, 2-mercapto-
 acetic acid, mercapto-
 glycolic acid, 2-thio-
 glycolic acid, thio-
 mercaptoacetic acid
2-mercaptoacetic acid
alpha-mercaptoacetic acid
 mercaptoethanoic acid
2-mercaptoethanoic acid
 sulfanylacetic acid
2-sulfanylacetic acid
2-thioglycolic acid
 thioglycolic acid-
 thioglycollic acid
 thiovanic acid
Synonyms   Articles   Notes   Search   Top
Articles:
PubMed: Efficient fluorescence resonance energy transfer between oppositely charged CdTe quantum dots and gold nanoparticles for turn-on fluorescence detection of glyphosate.
PubMed: Discovery of the highly potent fluoroquinolone-based benzothiazolyl-4-thiazolidinone hybrids as antibacterials.
PubMed: Determination of thioglycolic acid in cosmetics by capillary electrophoresis.
PubMed: Characterization of proanthocyanidins in stems of Polygonum multiflorum Thunb as strong starch hydrolase inhibitors.
PubMed: Gold nanoparticles-peptide based gas sensor arrays for the detection of food aromas.
PubMed: Sensitive fluorescent detection of melamine in raw milk based on the inner filter effect of Au nanoparticles on the fluorescence of CdTe quantum dots.
PubMed: Enhanced fluorescence sensing of melamine based on thioglycolic acid-capped CdS quantum dots.
PubMed: Profiles and α-amylase inhibition activity of proanthocyanidins in unripe Manilkara zapota (chiku).
PubMed: Rapid determination of melamine in milk using water-soluble CdTe quantum dots as fluorescence probes.
PubMed: An electrochemiluminescence sensor for determination of durabolin based on CdTe QD films by layer-by-layer self-assembly.
PubMed: Effects of thioglycolic acid on progesterone-induced maturation of Xenopus oocytes.
PubMed: New insights into the biodegradation of thiodiglycol, the hydrolysis product of Yperite (sulfur mustard gas).
PubMed: Thioglycolic acid inhibits mouse oocyte maturation and affects chromosomal arrangement and spindle configuration.
PubMed: Interference of condensed tannin in lignin analyses of dry bean and forage crops.
PubMed: Polyphenol oxidase activity and differential accumulation of polyphenolics in seed coats of pinto bean (Phaseolus vulgaris L.) characterize postharvest color changes.
PubMed: Application of a modified Haug and Lantzsch method for the rapid and accurate photometrical phytate determination in soybean, wheat, and maize meals.
PubMed: Thin self-assembled monolayer for voltammetrically monitoring nicotinic acid in food.
PubMed: Detection of deoxynivalenol based on a single-chain fragment variable of the antideoxynivalenol antibody.
PubMed: Synthesis and fungicidal activity of novel 4,4'-bis(2' '-aryl-5' '-methyl/unsubstituted-4' '-oxo-thiazolidin-3' '-yl) bibenzyl.
PubMed: A new micellar electrokinetic capillary chromatography method for separation of the components of the aminoglycoside antibiotics.
PubMed: Molecular cloning of a laccase isozyme gene from Pleurotus sajor-caju and expression in the heterologous Pichia pastoris host.
PubMed: Hydrogen peroxide is required for poly(phenolic) domain formation during wound-induced suberization.
PubMed: Development of a new medium for the isolation of Arcobacter spp.
PubMed: Inhibitory effect of diet related sulphydryl compounds on the formation of carcinogenic nitrosamines.
PubMed: Amino acid analysis for meat protein evaluation.
PubMed: Inactivation of aflatoxin B1 mutagenicity by thiols.
PubMed: High pressure liquid chromatographic determination of thioglycolic acid in cold wave fluids and depilating creams.
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