magnesium pyrophosphate
diphosphoric acid magnesium salt (1:2)
 
Notes:
None found
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CAS Number: 13446-24-7Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg: 236-595-0
FDA UNII: AL34Y660JV
MDL: MFCD00049482
Molecular Weight: 222.55192400
Formula: Mg2 O7 P2
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Category: leavening agents, acidity regulators
 
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DG SANTE Food Additives: magnesium dihydrogen diphosphate
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Physical Properties:
Food Chemicals Codex Listed: No
Specific Gravity: 2.56000 @  25.00 °C.
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
Santa Cruz Biotechnology
For experimental / research use only.
Magnesium Pyrophosphate
Sigma-Aldrich: Aldrich
For experimental / research use only.
Magnesium Pyrophosphate
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Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: leavening agents, acidity regulators
Recommendation for magnesium pyrophosphate usage levels up to:
 not for fragrance use.
 
Recommendation for magnesium pyrophosphate flavor usage levels up to:
 not for flavor use.
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Safety References:
European Food Safety Authority (EFSA) reference(s):
Re-evaluation of phosphoric acid–phosphates – di-, tri- and polyphosphates (E 338–341, E 343, E 450–452) as food additives and the safety of proposed extension of use
View page or View pdf
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EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 122213
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 3
 dimagnesium phosphonato phosphate
Chemidplus: 0013446247
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References:
 dimagnesium phosphonato phosphate
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 122213
Pubchem (sid): 135076866
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
HMDB (The Human Metabolome Database): Search
Export Tariff Code: 2835.39.5000
FDA Listing of Food Additive Status: View
ChemSpider: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
 dimagnesium phosphonato phosphate
 diphosphoric acid magnesium salt (1:2)
 magnesium dihydrogen diphosphate
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Articles:
PubMed: Demonstration of a very inexpensive, turbidimetric, real-time, RT-LAMP detection platform using shrimp Laem-Singh virus (LSNV) as a model.
PubMed: Layer-by-Layer Assembled Antisense DNA Microsponge Particles for Efficient Delivery of Cancer Therapeutics.
PubMed: A microfluidic system integrated with buried optical fibers for detection of Phalaenopsis orchid pathogens.
PubMed: Monitoring the progression of loop-mediated isothermal amplification using conductivity.
PubMed: RNAi-microsponges form through self-assembly of the organic and inorganic products of transcription.
PubMed: Low-tech detection methods for amplification products.
PubMed: Determination of phosphate phases in sewage sludge ash-based fertilizers by Raman microspectroscopy.
PubMed: Determination of phosphorus fertilizer soil reactions by Raman and synchrotron infrared microspectroscopy.
PubMed: Embryo sexing and sex chromosomal chimerism analysis by loop-mediated isothermal amplification in cattle and water buffaloes.
PubMed: Oxidation desensitizes actomyosin to magnesium pyrophosphate-induced dissociation.
PubMed: Struvite pyrolysate recycling combined with dry pyrolysis for ammonium removal from wastewater.
PubMed: Temperature-dependent phosphorus precipitation and chromium removal from struvite-saturated solutions.
PubMed: Combination of struvite pyrolysate recycling with mixed-base technology for removing ammonium from fertilizer wastewater.
PubMed: Development of a loop-mediated isothermal amplification assay for detection of Phytophthora sojae.
PubMed: A multiphysics model of in vitro transcription coupling enzymatic reaction and precipitation formation.
PubMed: Evaluation of certain food additives.
PubMed: Rapid detection of the most common high-risk human papillomaviruses by loop-mediated isothermal amplification.
PubMed: Detection of shrimp Taura syndrome virus by loop-mediated isothermal amplification using a designed portable multi-channel turbidimeter.
PubMed: Chemical composition and microstructure of uroliths associated with the feeding of high-level cottonseed meal diet to sheep.
PubMed: Insights into the importance of hydrogen bonding in the gamma-phosphate binding pocket of myosin: structural and functional studies of serine 236.
PubMed: Optimisation of reverse transcriptase loop-mediated isothermal amplification assay for rapid detection of Macrobrachium rosenbergii noda virus and extra small virus in Macrobrachium rosenbergii.
PubMed: Evaluation of trends in urolith composition and characteristics of dogs with urolithiasis: 25,499 cases (1985-2006).
PubMed: Real-time reverse transcription loop-mediated isothermal amplification for rapid detection of yellow head virus in shrimp.
PubMed: Rapid, sensitive and simple detection method for koi herpesvirus using loop-mediated isothermal amplification.
PubMed: Rapid and sensitive detection of Lophophora williamsii by loop-mediated isothermal amplification.
PubMed: Enhanced uridine diphosphate N-acetylglucosamine production using whole-cell catalysis.
PubMed: Sensitive and rapid detection of peach latent mosaic viroid by the reverse transcription loop-mediated isothermal amplification.
PubMed: State-dependent modulation of CFTR gating by pyrophosphate.
PubMed: Colorimetric detection of loop-mediated isothermal amplification reaction by using hydroxy naphthol blue.
PubMed: Detection of Ralstonia solanacearum by loop-mediated isothermal amplification.
PubMed: Examination of intrinsic sulfonamide resistance in Bacillus anthracis: a novel assay for dihydropteroate synthase.
PubMed: Rapid identification of Curcuma longa and C. aromatica by LAMP.
PubMed: Evaluation of trends in urolith composition in cats: 5,230 cases (1985-2004).
PubMed: Rapid detection of Actinobacillus actinomycetemcomitans using a loop-mediated isothermal amplification method.
PubMed: ATP as effector of inorganic pyrophosphatase of Escherichia coli. Identification of the binding site for ATP.
PubMed: Binding of substrate at the effector site of pyrophosphatase increases the rate of its hydrolysis at the active site.
PubMed: X-ray crystal structure of aristolochene synthase from Aspergillus terreus and evolution of templates for the cyclization of farnesyl diphosphate.
PubMed: Rapid and sensitive detection of heat-labile I and heat-stable I enterotoxin genes of enterotoxigenic Escherichia coli by Loop-Mediated Isothermal Amplification.
PubMed: Rapid detection of Macrobrachium rosenbergii nodavirus (MrNV) and extra small virus (XSV), the pathogenic agents of white tail disease of Macrobrachium rosenbergii (De Man), by loop-mediated isothermal amplification.
PubMed: Detection of canine parvovirus in fecal samples using loop-mediated isothermal amplification.
PubMed: The determination of phosphorus containing compounds in dental casting investment products by 31P solid-state MAS-NMR spectroscopy.
PubMed: Sensitive and rapid detection of infectious hypodermal and hematopoietic necrosis virus (IHHNV) in shrimps by loop-mediated isothermal amplification.
PubMed: Removal of aqueous ammonium with magnesium phosphates obtained from the ammonium-elimination of magnesium ammonium phosphate.
PubMed: [A cationic cluster of amino acid residues of inorganic pyrophosphatase from Escherichia coli as a possible site of effector binding].
PubMed: Kinetic studies of yeast polyA polymerase indicate an induced fit mechanism for nucleotide specificity.
PubMed: Metal-free PPi activates hydrolysis of MgPPi by an Escherichia coli inorganic pyrophosphatase.
PubMed: Detection of periodontal pathogen Porphyromonas gingivalis by loop-mediated isothermal amplification method.
PubMed: [Principle of LAMP method--a simple and rapid gene amplification method].
PubMed: Rapid detection of a fish iridovirus using loop-mediated isothermal amplification (LAMP).
PubMed: Real-time turbidimetry of LAMP reaction for quantifying template DNA.
PubMed: Detection of Japanese yam mosaic virus by RT-LAMP.
PubMed: Use of loop-mediated isothermal amplification of the IS900 sequence for rapid detection of cultured Mycobacterium avium subsp. paratuberculosis.
PubMed: Detection of tomato yellow leaf curl virus by loop-mediated isothermal amplification reaction.
PubMed: Detection of loop-mediated isothermal amplification reaction by turbidity derived from magnesium pyrophosphate formation.
PubMed: Structural characterization of the enzyme-substrate, enzyme-intermediate, and enzyme-product complexes of thiamin phosphate synthase.
PubMed: A transition-state analogue reduces protein dynamics in hypoxanthine-guanine phosphoribosyltransferase.
PubMed: Crystal structures of Giardia lamblia guanine phosphoribosyltransferase at 1.75 A(,).
PubMed: Mechanism of Ca2+-induced inhibition of Escherichia coli inorganic pyrophosphatase.
PubMed: The 2.0 A structure of human hypoxanthine-guanine phosphoribosyltransferase in complex with a transition-state analog inhibitor.
PubMed: Transition-state analogs as inhibitors of human and malarial hypoxanthine-guanine phosphoribosyltransferases.
PubMed: Motional dynamics of the catalytic loop in OMP synthase.
PubMed: Bacillus subtilis ORF yybQ encodes a manganese-dependent inorganic pyrophosphatase with distinctive properties: the first of a new class of soluble pyrophosphatase?
PubMed: Purification, properties, and multiple forms of a manganese-activated inorganic pyrophosphatase from Bacillus subtilis.
PubMed: The Role of Magnesium, Pyrophosphate, and Their Complexes as Substrates and Activators of the Vacuolar H+-Pumping Inorganic Pyrophosphatase (Studies Using Ligand Protection from Covalent Inhibitors).
PubMed: Catalysis by Escherichia coli inorganic pyrophosphatase: pH and Mg2+ dependence.
PubMed: The importance of conserved residues in human liver UDPglucose pyrophosphorylase.
PubMed: Cross-bridge binding to actin and force generation in skinned fibers of the rabbit psoas muscle in the presence of antibody fragments against the N-terminus of actin.
PubMed: X-ray structure of the magnesium(II)-pyrophosphate complex of the truncated head of Dictyostelium discoideum myosin to 2.7 A resolution.
PubMed: Location and properties of pyrophosphate-binding sites in Escherichia coli F1-ATPase.
PubMed: Interactions of calcium and magnesium with the mitochondrial inorganic pyrophosphatase from Saccharomyces cerevisiae.
PubMed: Localization of two myosin-subfragment-1 binding contacts in the 96-132 region of actin subdomain-1.
PubMed: State-dependent radial elasticity of attached cross-bridges in single skinned fibres of rabbit psoas muscle.
PubMed: Inorganic pyrophosphatase from bovine retinal rod outer segments.
PubMed: Kinetics of the Vacuolar H-Pyrophosphatase : The Roles of Magnesium, Pyrophosphate, and their Complexes as Substrates, Activators, and Inhibitors.
PubMed: Crystal chemistry of Mg2P2O7.nH2O, n = 0, 2 and 6: magnesium-oxygen coordination and pyrophosphate ligation and conformation.
PubMed: Effects of magnesium pyrophosphate on mechanical properties of skinned smooth muscle from the guinea pig taenia coli.
PubMed: Two pathways of pyrophosphate hydrolysis and synthesis by yeast inorganic pyrophosphatase.
PubMed: Steady-state kinetics of the schistosomal hypoxanthine-guanine phosphoribosyltransferase.
PubMed: The molecular origin of birefringence in skeletal muscle. Contribution of myosin subfragment S-1.
PubMed: Effect of ionic strength on skinned rabbit psoas fibers in the presence of magnesium pyrophosphate.
PubMed: Effect of nucleotides, actin and temperature on thermolysin digestion of myosin subfragment-1.
PubMed: Properties of a polycation-stimulated protein kinase associated with purified Avena phytochrome.
PubMed: Comparative studies on the electrical properties of the H+ translocating ATPase and pyrophosphatase of the vacuolar-lysosomal compartment.
PubMed: [Introduction of an enzyme method for determining pyrophosphate in urine--a comparative study between patients with calculi and normal probands].
PubMed: [The effect of pyrophosphate on the rigor fibers of rabbit m. psoas fibers].
PubMed: The effect of pyrophosphate on the reaction of myosin with 2,4,6-trinitrobenzene sulphonate.
PubMed: Energetics of the actomyosin bond in the filament array of muscle fibers.
PubMed: Manganese complexes and the generation and scavenging of hydroxyl free radicals.
PubMed: The medical and metabolic consequences of administration of sodium acetate.
PubMed: The effects of pyrophosphate on myosin heads and on fiber stiffness.
PubMed: Possible cooperativity in crossbridge detachment in muscle fibers having magnesium pyrophosphate at the active site.
PubMed: Effect of glycosaminoglycans on calcium pyrophosphate crystal formation in collagen gels.
PubMed: Proximity and ligand-induced movement of interdomain residues in myosin subfragment 1 containing trapped MgADP and MgPPi probed by multifunctional cross-linking.
PubMed: Ca2+-sensitive cross-bridge dissociation in the presence of magnesium pyrophosphate in skinned rabbit psoas fibers.
PubMed: The myosin filament. XII. Effect of MgATP on assembly.
PubMed: Stiffness of skinned rabbit psoas fibers in MgATP and MgPPi solution.
PubMed: Actin-attached and detached crossbridges in myofibrils: segregation into two populations according to their sensitivity to proteolytic digestion of myosin heavy chain.
PubMed: Resolution of the competitive inhibitory effects of lithium and AMPPNP on the beat frequency of ATP-reactivated, demembranated, sea urchin sperm flagella.
PubMed: The quaternary structure of E. coli inorganic pyrophosphatase is not required for catalytic activity.
PubMed: Tryptic digestion of rabbit skeletal myofibrils: an enzymatic probe of myosin cross-bridges.
PubMed: Investigation of the role of the substrate metal ion in the yeast inorganic pyrophosphatase reaction.
PubMed: Stepwise changes in crossbridge state and sarcomere length: do lattice constraints play a critical role?
PubMed: Kinetic anticooperativity in pre-steady-state formation of tryptophanyl adenylate by tryptophanyl-tRNA synthetase from beef pancreas. A consequence of the tryptophan anticooperative binding.
PubMed: The stereochemical course of nucleotidyl transfer catalyzed by ATP sulfurylase.
PubMed: [Some features of methylpyrophosphate hydrolysis by yeast inorganic pyrophosphatase].
PubMed: Calcium and ATP regulation of the oscillatory torsional movement in a triton model of Physarum plasmodial strands.
PubMed: Inorganic pyrophosphatase activity in oral streptococci: purification and properties of the enzyme from Streptococcus salivarius.
PubMed: The effect of calcium and magnesium ions on calcium pyrophosphate crystal formation in aqueous solutions.
PubMed: Reactive lysyl of myosin subfragment 1: location on the 27K fragment and labeling properties.
PubMed: Calcium pyrophosphate crystal formation in aqueous solutions.
PubMed: Internal motions in myosin.
PubMed: Kinetic studies of the interaction of uranyl ions with inorganic pyrophosphatase from baker's yeast.
PubMed: Immobilized ATP and actin columns as a tool for the characterization and separation of different myosins and active myosin fragments.
PubMed: Purification and characterization of myosin from the clonal rat glial cell strain C-6.
PubMed: Determination of phosphorus in phosphazenes and phosphines.
PubMed: Inhibitor of spinach chloroplast fructose-1,6-diphosphatase by MgATP--,MgADP-and magnesium pyrophosphate (MgP207--).
PubMed: Interactions between magnesium, pyrophosphate, and the contractile elements.
PubMed: The relation between the magnesium-pyrophosphate complex and the actomyosin reaction to adenosinetriphosphate.
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