isobutyramide, 563-83-7

Articles:

PubMed:	Templated assembly of albumin-based nanoparticles for simultaneous gene silencing and magnetic resonance imaging.
PubMed:	Liquid-liquid extraction of uranyl by an amide ligand: interfacial features studied by MD and PMF simulations.
PubMed:	Cytotoxic (A549) and antimicrobial effects of Methylobacterium sp. isolate (ERI-135) from Nilgiris forest soil, India.
PubMed:	Protein capsules assembled via isobutyramide grafts: sequential growth, biofunctionalization, and cellular uptake.
PubMed:	Hyperbranched polymers with thermoresponsive property highly sensitive to ions.
PubMed:	Bromoisobutyramide as an intermolecular surface binder for the preparation of free-standing biopolymer assemblies.
PubMed:	Cloning and characterization of a novel amidase from Paracoccus sp. M-1, showing aryl acylamidase and acyl transferase activities.
PubMed:	Thermodynamics of hyperbranched poly(ethylenimine) with isobutyramide residues during phase transition: an insight into the molecular mechanism.
PubMed:	Thermosensitive molecular assemblies from poly(amidoamine) dendron-based lipids.
PubMed:	A new acylamidase from Rhodococcus erythropolis TA37 can hydrolyze N-substituted amides.
PubMed:	Exploring the neuroleptic substituent in octoclothepin: potential ligands for positron emission tomography with subnanomolar affinity for α(1)-adrenoceptors.
PubMed:	Establishment of steady-state metabolism of ethanol in perfused rat liver: the quantitative analysis using kinetic mechanism-based rate equations of alcohol dehydrogenase.
PubMed:	The effects of stressful stimuli and hypothalamic-pituitary-adrenal axis activation are reversed by the melanin-concentrating hormone 1 receptor antagonist SNAP 94847 in rodents.
PubMed:	R-stereoselective amidase from Rhodococcus erythropolis No. 7 acting on 4-chloro-3-hydroxybutyramide.
PubMed:	Me-talnetant and osanetant interact within overlapping but not identical binding pockets in the human tachykinin neurokinin 3 receptor transmembrane domains.
PubMed:	Synthesis and SAR investigations for novel melanin-concentrating hormone 1 receptor (MCH1) antagonists Part 1. The discovery of arylacetamides as viable replacements for the dihydropyrimidinone moiety of an HTS hit.
PubMed:	Structural evidence for a ligand coordination switch in liver alcohol dehydrogenase.
PubMed:	A novel thermostable nitrilase superfamily amidase from Geobacillus pallidus showing acyl transfer activity.
PubMed:	Cloning and nucleotide sequence of carbaryl hydrolase gene (cahA) from Arthrobacter sp. RC100.
PubMed:	Metabolism, pharmacokinetics, tissue distribution, and excretion of [14C]CP-424391 in rats.
PubMed:	Discovery and SAR of 2-aminothiazole inhibitors of cyclin-dependent kinase 5/p25 as a potential treatment for Alzheimer's disease.
PubMed:	Rendering poly(amidoamine) or poly(propylenimine) dendrimers temperature sensitive.
PubMed:	Purification and properties of an enantioselective and thermoactive amidase from the thermophilic actinomycete Pseudonocardia thermophila.
PubMed:	Isobutyramide activates transcription of human fetal gamma- and murine embryonic epsilon(y)-globin genes.
PubMed:	[Isobutyramide activates transcription of human fetal gamma-globin gene selectively].
PubMed:	Induction of fetal hemoglobin expression by the histone deacetylase inhibitor apicidin.
PubMed:	Enantioselective synthesis of 2-substituted 2-phenylethylamines by lithiation-substitution sequences: synthetic development and mechanistic pathway.
PubMed:	A New Structural Class of Bisindole Alkaloids from the Seeds of Catharanthus roseus: Vingramine and Methylvingramine.
PubMed:	Overexpression of Bcl-2 regulates sodium butyrate- and/or docetaxel-induced apoptosis in human bladder cancer cells both in vitro and in vivo.
PubMed:	Induction of the apolipoprotein AI gene by fasting: a relationship with ketosis but not with ketone bodies.
PubMed:	Oral isobutyramide reduces transfusion requirements in some patients with homozygous beta-thalassemia.
PubMed:	Enzymatic kinetic resolution of piperidine atropisomers: synthesis of a key intermediate of the farnesyl protein transferase inhibitor, SCH66336.
PubMed:	Effects of ketoacidosis on rat apolipoprotein A1 gene expression: a link with acidosis but not with ketones.
PubMed:	Oral isobutyramide therapy in patients with thalassemia intermedia: results of a phase II open study.
PubMed:	A combination of hydroxyurea and isobutyramide to induce fetal hemoglobin in transgenic mice is more hematotoxic than the individual agents.
PubMed:	Acyl transfer activity of an amidase from Rhodococcus sp. strain R312: formation of a wide range of hydroxamic acids.
PubMed:	Butyrate trials.
PubMed:	Butyrate analogue, isobutyramide, inhibits tumor growth and time to androgen-independent progression in the human prostate LNCaP tumor model.
PubMed:	Optical spectroscopy of nicotinoprotein alcohol dehydrogenase from Amycolatopsis methanolica: a comparison with horse liver alcohol dehydrogenase and UDP-galactose epimerase.
PubMed:	The protein conformation of Cd-substituted horse liver alcohol dehydrogenase and its metal-site coordination geometry in binary and ternary inhibitor complexes.
PubMed:	Pharmacokinetics and safety of single oral doses of VX-366 (isobutyramide) in healthy volunteers.
PubMed:	Isobutyramide therapy in patients with sickle cell anemia.
PubMed:	Discordant effects of butyrate analogues on erythroleukemia cell proliferation, differentiation and histone deacetylase.
PubMed:	Nanosecond time-resolved circular polarization of fluorescence: study of NADH bound to horse liver alcohol dehydrogenase.
PubMed:	Analysis of equilibrium binding data obtained by linear-response spectroscopic techniques.
PubMed:	Isobutyramide, an orally bioavailable butyrate analogue, stimulates fetal globin gene expression in vitro and in vivo.
PubMed:	Purification and characterization of an amidase from an acrylamide-degrading Rhodococcus sp.
PubMed:	Increased fetal hemoglobin production in patients receiving valproic acid for epilepsy.
PubMed:	Butyrate derivatives. New agents for stimulating fetal globin production in the beta-globin disorders.
PubMed:	Butyrate-induced reactivation of the fetal globin genes: a molecular treatment for the beta-hemoglobinopathies.
PubMed:	The importance of alcohol dehydrogenase in regulation of ethanol metabolism in rat liver cells.
PubMed:	Extremely long protection by pyrazole derivatives against chemically induced gastric mucosal injury.
PubMed:	Room temperature phosphorescence of Trp-314 as a monitor of subunit communications in alcohol dehydrogenase from horse liver.
PubMed:	Tryptophan luminescence from liver alcohol dehydrogenase in its complexes with coenzyme. A comparative study of protein conformation in solution.
PubMed:	Degradation of Acetonitrile by Pseudomonas putida.
PubMed:	Analysis of the inactivation of liver alcohol dehydrogenase during storage in Aerosol-OT/isooctane microemulsions.
PubMed:	Deuterium isotope effects on ethanol oxidation in perfused rat liver and in rats and rabbits in vivo: application to determine the contribution of various pathways.
PubMed:	Deuterium isotope effects as a tool in the study of ethanol oxidation in rat liver microsomes.
PubMed:	Classical Raman spectroscopic studies of NADH and NAD+ bound to liver alcohol dehydrogenase by difference techniques.
PubMed:	Active-site cobalt(II)-substituted horse liver alcohol dehydrogenase: characterization of intermediates in the oxidation and reduction processes as a function of pH.
PubMed:	Reductases for carbonyl compounds in human liver.
PubMed:	Kinetics of inhibition of ethanol metabolism in rats and the rate-limiting role of alcohol dehydrogenase.
PubMed:	Steady-state kinetics of horse-liver alcohol dehydrogenase with a covalently bound coenzyme analogue.
PubMed:	Inactivation of horse liver alcohol dehydrogenase by modification of cysteine residue 174 with 3-bromopropionic acid.
PubMed:	Binding of NADH to horse liver alcohol dehydrogenase: dependence on concentration of benzaldehyde and benzyl alcohol.
PubMed:	Involvement of histidine residues in the activity of horse liver alcohol dehydrogenase.
PubMed:	Physiological function and kinetic mechanism of human liver alcohol dehydrogenase as 5 beta-cholestane-3 alpha,7 alpha,12 alpha,26-tetrol dehydrogenase.
PubMed:	Alcohol dehydrogenase from the fruitfly Drosophila melanogaster. Inhibition studies of the alleloenzymes AdhS and AdhUF.
PubMed:	pH variation of isotope effects in enzyme-catalyzed reactions. 2. Isotope-dependent step not pH dependent. Kinetic mechanism of alcohol dehydrogenase.
PubMed:	Spectral evidence for tyrosine ionization linked to a conformational change in liver alcohol dehydrogenase ternary complexes.
PubMed:	The interaction of liver alcohol dehydrogenase with NADH as studied by differential protein denaturation.
PubMed:	The role of acetaldehyde in mediating the deleterious effect of ethanol on pyridoxal 5'-phosphate metabolism.
PubMed:	Circular dichroic properties and conformation of thionicotinamide dinucleotides bound to horse-liver alcohol dehydrogenase.
PubMed:	Water and nonelectrolyte permeability of lipid bilayer membranes.
PubMed:	Dissociation and rate constants of some human liver alcohol dehydrogenase isoenzymes.
PubMed:	Nuclear magnetic resonance studies of substrate interaction with cobalt substituted alcohol dehydrogenase from liver.
PubMed:	Kinetic equivalence of the active sites of alcohol dehydrogenase from horse liver.
PubMed:	The membrane action of antidiuretic hormone (ADH) on toad urinary bladder.
PubMed:	Chemical relaxation studies on the system liver alcohol dehydrogenase, NADH and imidazole.
PubMed:	Magnetic resonance studies of the geometry of bound nicotinamide adenine dinucleotide and isobutyramide on spin-labeled alcohol dehydrogenase.
PubMed:	Temperature dependence of nonelectrolyte permeation across red cell membranes.
PubMed:	Protein fluorescence of nicotinamide nucleotide-dependent dehydrogenases.
PubMed:	Heterogeneity of liver alcohol dehydrogenase on starch-gel electrophoresis.
PubMed:	Crystallization of binary and ternary complexes of horse liver alcohol dehydrogenase with DPNH and with DPNH and isobutyramide.
PubMed:	On the ternary complex of liver alcohol dehydrogenase with reduced coenzyme and isobutyramide. Effect of p-chloromercuriphenyl sulfonate and stability of the complex.