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Category: dietary supplements
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | white crystalline powder (est) |
| Assay: | 98.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Melting Point: | 254.00 to 255.00 °C. @ 760.00 mm Hg
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| Boiling Point: | 897.00 to 898.00 °C. @ 760.00 mm Hg (est)
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| Flash Point: | 925.00 °F. TCC ( 496.30 °C. ) (est)
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| logP (o/w): | 3.945 (est) |
| Soluble in: |
| | acetone | | | alcohol | | | water, 0.2853 mg/L @ 25 °C (est) |
| Insoluble in: |
| | water |
Organoleptic Properties:
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-rat LD50 > 20000 mg/kg Oyo Yakuri. Pharmacometrics. Vol. 14(5), Pg. 741, 1977.
intravenous-rat LD50 268 mg/kg Drugs in Japan Vol. 6, Pg. 77, 1982.
intraperitoneal-rat LD50 > 10000 mg/kg Oyo Yakuri. Pharmacometrics. Vol. 14(5), Pg. 741, 1977.
oral-mouse LD50 > 30000 mg/kg Oyo Yakuri. Pharmacometrics. Vol. 7, Pg. 149, 1973.
intravenous-mouse LD50 345 mg/kg Drugs in Japan Vol. 6, Pg. 77, 1982.
intraperitoneal-mouse LD50 6400 mg/kg LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) Oyo Yakuri. Pharmacometrics. Vol. 7, Pg. 149, 1973.
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| Dermal Toxicity: |
subcutaneous-rat LD50 1180 mg/kg Drugs in Japan Vol. 6, Pg. 77, 1982.
subcutaneous-mouse LD50 > 5000 mg/kg Oyo Yakuri. Pharmacometrics. Vol. 14(5), Pg. 741, 1977.
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | dietary supplements |
| Recommendation for inositol niacinate usage levels up to: | | | not for fragrance use.
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| Recommendation for inositol niacinate flavor usage levels up to: |
| | not for flavor use.
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Safety References:
| European Food Safety Authority (EFSA) reference(s): |
Inositol hexanicotinate (inositol hexaniacinate) as a source of niacin (vitamin B3) added for nutritional purposes in food supplements View page or View pdf |
Scientific Opinion on the substantiation of a health claim related to the combination of artichoke leaf dry extract standardised in caffeoylquinic acids, monacolin K in red yeast rice, sugar-cane derived policosanols, OPC from French maritime pine bark, garlic dry extract standardised in allicin, d-a-tocopheryl hydrogen succinate, riboflavin and inositol hexanicotinate in Limicol® and reduction of blood LDL-cholesterol concentrations pursuant to Article 14 of Regulation (EC) No 1924/2006 View page or View pdf |
| EPI System: | View |
| Daily Med: | search |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 3720 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 2 |
| | [2,3,4,5,6-pentakis(pyridine-3-carbonyloxy)cyclohexyl] pyridine-3-carboxylate |
| Chemidplus: | 0006556112 |
| RTECS: | NM7535400 for cas# 6556-11-2 |
References:
| | [2,3,4,5,6-pentakis(pyridine-3-carbonyloxy)cyclohexyl] pyridine-3-carboxylate |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 3720 |
| Pubchem (sid): | 135264266 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | cyclohexane-1,2,3,4,5,6-hexayl hexanicotinate | | | cyclohexane-1,2,3,4,5,6-hexayl hexapyridine-3-carboxylate | | | hexanicotinoyl inositol | | | inositol hexanicotinate | | | inositol nicotinate | | | inositol, hexanicotinate, myo- | | | inositoli nicotinas | | | mesonex | | 2,3,4,5,6- | pentakis((3-pyridinylcarbonyl)oxy)cyclohexyl nicotinate | | [2,3,4,5,6- | pentakis(pyridine-3-carbonyloxy)cyclohexyl] pyridine-3-carboxylate | | 3- | pyridinecarboxylic acid, 1,2,3,4,5,6-cyclohexanehexayl ester |
Articles:
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