Articles:
cellulose, 2-hydroxypropyl ether
Notes:
component of contact lens wetting solutions. Hydroxypropyl cellulose (cellulose, 2-hydroxypropyl ether) is a derivative of cellulose with both water solubility and organic solubility. Hydroxypropyl cellulose acts to stabilize and thicken the precorneal tear film and prolong the tear film breakup time which is usually accelerated in patients with dry eye states. Hydroxypropyl cellulose also acts to lubricate and protect the eye. Hydroxypropyl cellulose usually reduces the signs and symptoms resulting from moderate to severe dry eye syndromes, such as conjunctival hyperemia, corneal and conjunctival staining with rose bengal, exudation, itching, burning, foreign body sensation, smarting, photophobia, dryness and blurred or cloudy vision. Progressive visual deterioration which occurs in some patients may be retarded, halted, or sometimes reversed.
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BOC Sciences Best of Chemicals Supplier Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services. BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies. Email: Marketing US Email: Marketing Email: Sales US Email: Sales Voice: 1-631-485-4226 Fax: 1-631-614-7828 US Voice: 1-631-485-4226 US Fax: 1-631-614-7828 Europe 44-203-286-1088 Facebook Twitter Linkedin Blog Get the App! Product(s): 9004-64-2 Hydroxypropyl Cellulose
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ECSA Chemicals Human Chemistry ECSA Chemicals has been active since 1913 in the trading and international commerce of raw materials. With an organisation divided into industrial segments managed by specialists, it has become one of the largest distributors worldwide. ECSA Chemicals is the largest Swiss-owned company in terms of warehouses for the distribution of chemical products. We have been distributing chemical products for over 100 years and we have a special interest in protecting the environment and in the safety of our facilities and collaborators. Established in 1913 as a small grocery store, in its over 100 years of activity ECSA Chemicals has become one of the most important Swiss-owned distributors of chemical products. The company, which is active in international distribution and trading, is organised into industrial segments that are managed by teams of specialists and experts. They guarantee professional and customised consultancy and services. With our experience, we can rapidly and safely connect you with the best suppliers on the market, providing you with a complete search, consulting and assistance service. The focus of our approach and operations is you, our customers. We strive every day to find the best products that satisfy your needs as quickly as possible. Your satisfaction is our greatest success. WHY CHOOSE ECSA? EXPERIENCE We have been working for 100 years. QUALITY We have obtained many certifications (ISO, SQAS, GDP, Responsible Care, Bio-Inspecta, RSPO, etc.). We guarantee full compliance with the current laws and continuous training for our staff. SAFETY We constantly carry out risk analyses for each infrastructure, defining safety levels and implementing corrective measures promptly wherever they are needed. WIDESPREAD DISTRIBUTION We have warehouses in strategic locations to supply goods to Switzerland and to the rest of the world. STORAGE CAPACITY The 3 ECSA-owned warehouses guarantee considerable storage area and capacity in each warehouse, with full availability of products (base chemicals and speciality chemicals). SPEED Presence all over the country, staff dedicated to sourcing raw materials and considerable storage capacity guarantee that goods are rapidly obtained and supplied. CONSULTANCY Our specialists - in-depth knowledge of the market and products allows us to provide full consulting services, from the purchase to the supply of raw materials. Email: Info Email: Sales Email: Trading Email: Maintenance Email: Energy Voice: +41 91 695 88 00 Fax: +41 91 695 88 01 Linkedin Youtube RSS Feed ECSA Trade ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY Products List: View Product(s): MP-030335 KLUCEL NUTRA D
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Glentham Life Sciences Ltd The Chemical, Biochemical & Research Essentials Supplier Glentham Life Sciences is a supplier of fine chemicals and raw materials with warehousing, laboratories and packaging facilities in the UK. With a Glentham Life Sciences account you can view more product details, request quotes and order products online. Email: Info Email: Sales Email: Tech Support Voice: +44 (0) 1225 667798 Fax: +44 (0) 2033 978909 Facebook Twitter Linkedin Google+ News Distribution Products List: View Product(s): GC4566 Hydroxypropyl cellulose
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TCI AMERICA Moving Your Chemistry Forward We continuously strive to advance our technology. With East & West Coast distribution centers, count on TCI to deliver products quickly and reliably. Over 30,000 Reagents available today in benchtop to bulk quantities. We also offer custom synthesis solutions. Sign up for a TCI account today for fast and free shipping! Tokyo Chemical Industry Co., Ltd. (TCI) is a leading worldwide manufacturer of specialty organic chemicals founded in 1946. TCI provides organic laboratory chemicals as well as pharmaceutical, cosmetic and functional materials. More than 70 years of synthesis experience and multi-purpose plants enable TCI to offer more than 30,000 products as well as custom synthesis. US Email: Sales Email: Technical Support Voice: 1-800-423-8616 Fax: 1- 888-520-1075 Facebook Twitter Instagram Linkedin Product(s): H0386 Hydroxypropyl Cellulose (150-400mPa·s, 2% in Water at 20°C)
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| CAS Number: | 9004-64-2 | |
| Other(deleted CASRN): | 1374408-53-3 | |
| FDA UNII: | 2165RE0K14 | |
| MDL: | MFCD00132688 | |
| Formula: | C3 H8 O2.x-unspecified | |
Category: multipurpose additives, foam promoter, mouthfeel, stabilizer
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Perfumer and Flavorist: | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
| FDA/DG SANTE Petitions, Reviews, Notices: | |
| FR DOC # 2011-17928 | Food Additives Permitted for Direct Addition to Food for Human Consumption; Hydroxypropyl Cellulose Pages 41687 - 41689 View - petition PDF |
| JECFA Food Additive: | Hydroxypropyl Cellulose |
| GSFA Codex: | Hydroxypropyl cellulose (463) |
| DG SANTE Food Additives: | hydroxypropyl cellulose |
| DG SANTE Food Contact Materials: | hydroxypropyl cellulose |
| FDA Mainterm (SATF): | 9004-64-2 ; HYDROXYPROPYL CELLULOSE |
| FDA Regulation: | |
| FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION Subpart I--Multipurpose Additives Sec. 172.870 Hydroxypropyl cellulose. FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS Subpart B--Substances for Use as Basic Components of Single and Repeated Use Food Contact Sec. 177.1200 Cellophane. FDA PART 73 -- LISTING OF COLOR ADDITIVES EXEMPT FROM CERTIFICATION Subpart B--Drugs Sec. 73.1001 Diluents in color additive mixtures for drug use exempt from certification. | |
Physical Properties:
| Appearance: | white to pale yellow powder (est) |
| Assay: | 95.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
Organoleptic Properties:
| Odor Description: at 100.00 %. | odorless |
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| CosIng: | cosmetic data |
| Cosmetic Uses: |
binding agents emulsion stabilisers film formers surfactant - emulsifying viscosity controlling agents |
Suppliers:
| Achiewell |
| For experimental / research use only. |
| Hydroxypropyl Cellulose (HPC) |
| Ashland |
| AeroWhip™ hydroxypropylcellulose
Odor: odorless Use: AeroWhip 630 hydroxypropylcellulose (HPC) is an optimized grade of HPC for stabilizing dairy and nondairy whipped toppings. In nondairy whipped toppings, AeroWhip 630 HPC creates stiff foams, increases overrun and controls syneresis. For dairy whipping creams, the amount of milk fat can be reduced significantly, leading to a healthier and more cost-effective product with a creamy mouthfeel. AeroWhip 630 HPC is compatible with common emulsifier and stabilizer ingredients. |
| Ashland |
| Klucel™ hydroxypropylcellulose
Odor: odorless Use: Klucel hydroxypropylcellulose (HPC) is a nonionic water-soluble cellulose ether with a remarkable combination of properties. It combines organic solvent solubility, thermoplasticity and surface activity with the aqueous thickening and stabilizing properties characteristic of other water-soluble cellulose polymers available from Ashland. Klucel HPC films are flexible without plasticizers and non-tacky at high humidity. |
| Ashland |
| PrimaFlo™ HP22 polymer solution
Odor: odorless Use: PrimaFlo HP22 polymer solution is an aqueous solution of hydroxypropylcellulose (HPC) developed specifically for use as a film-former in personal care formulations. It is fully compatible with hydro-alcoholic systems. Typical use levels are 2 to 5 percent (wet basis). The benefit of PrimaFlo HPC versus Klucel™ hydroxypropylcellulose is that PrimaFlo is ready to use, saving the time and cost of dissolving. |
| BOC Sciences |
| For experimental / research use only. |
| Hydroxypropyl Cellulose |
| ECSA Chemicals |
| KLUCEL NUTRA D |
| ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY |
| Glentham Life Sciences |
| Hydroxypropyl cellulose |
| Kraft Chemical |
| HydroxyPropylCellulose |
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| Hydroxypropyl Cellulose |
| Sigma-Aldrich: Aldrich |
| For experimental / research use only. |
| Hydroxypropyl cellulose
average Mw ∼80,000, average Mn ∼10,000, powder, 20 mesh particle size (99% through) |
| TCI AMERICA |
| For experimental / research use only. |
| Hydroxypropyl Cellulose (150-400mPa·s, 2% in Water at 20°C) |
Safety Information:
| Preferred SDS: View | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
|
oral-rat LD50 10200 mg/kg FAO Nutrition Meetings Report Series. Vol. 46A, Pg. 131, 1969. intravenous-rat LD50 250 mg/kg Oyo Yakuri. Pharmacometrics. Vol. 4, Pg. 1013, 1970. intraperitoneal-rat LD50 > 25000 mg/kg Oyo Yakuri. Pharmacometrics. Vol. 4, Pg. 1013, 1970. oral-mouse LD50 > 5000 mg/kg Oyo Yakuri. Pharmacometrics. Vol. 4, Pg. 1013, 1970. intravenous-mouse LD50 > 500 mg/kg Oyo Yakuri. Pharmacometrics. Vol. 4, Pg. 1013, 1970. intraperitoneal-mouse LD50 > 25000 mg/kg Oyo Yakuri. Pharmacometrics. Vol. 4, Pg. 1013, 1970. | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | multipurpose additives, foam promoter, mouthfeel, stabilizer | ||
| Recommendation for hydroxypropyl cellulose usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for hydroxypropyl cellulose flavor usage levels up to: | |||
| not for flavor use. | |||
Safety References:
| European Food Safety Authority (EFSA) reference(s): | |
| Re-evaluation of celluloses E 460(i), E 460(ii), E 461, E 462, E 463, E 464, E 465, E 466, E 468 and E 469 as food additives View page or View pdf | |
| Safety of low-substituted hydroxypropyl cellulose (L-HPC) to be used as a food additive in food supplements in tablet form View page or View pdf | |
| Safety and efficacy of hydroxypropyl cellulose for all animal species View page or View pdf | |
| ClinicalTrials.gov: | search |
| Daily Med: | search |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA Substance Registry Services (TSCA): | 9004-64-2 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 1 |
| Chemidplus: | 0009004642 |
| RTECS: | NF9050000 for cas# 9004-64-2 |
References:
| Canada Domestic Sub. List: | 9004-64-2 |
| Pubchem (sid): | 135020743 |
Other Information:
| FDA Substances Added to Food (formerly EAFUS): | View |
| FDA Indirect Additives used in Food Contact Substances: | View |
| HMDB (The Human Metabolome Database): | HMDB32337 |
| FooDB: | FDB009612 |
| Export Tariff Code: | 3912.39.0000 |
| FDA Listing of Food Additive Status: | View |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| binding agents | ||
| emulsion stabilisers | ||
| film formers | ||
| gel forming agents for perfumes | ||
| viscosity controlling agents |
Occurrence (nature, food, other): note
| not found in nature |
Synonyms:
| cellulose 2-hydroxypropyl ether | |
| cellulose hydroxypropyl ether | |
| cellulose, 2-hydroxypropyl ether | |
| 2- | hydroxypropyl cellulose |
| hydroxypropyl ether of cellulose | |
| hydroxypropylcellulose | |
| oxy | propylated cellulose |