Articles:
9H-pyrido[3,4-b]indole, 7-methoxy-1-methyl-, hydrochloride (1:1)
Notes:
alkaloid isolated from seeds of peganum harmala l., zygophyllaceae. it is identical to banisterine, or telepathine, from banisteria caapi and is one of the active ingredients of hallucinogenic drinks made in the western amazon region from related plants. it has no therapeutic use, but (as banisterine) was hailed as a cure for postencephalitic parkinson disease in the 1920's.
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Penta International Corporation Chemistry innovation At Penta, our products and services help businesses do business better. For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes. US Email: Technical Services US Email: Sales US Voice: (973) 740-2300 US Fax: (973) 740-1839 Product(s): 08-00800 HARMINE HYDROCHLORIDE
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| CAS Number: | 343-27-1 |  3D/inchi
|
| ECHA EINECS - REACH Pre-Reg: | 206-443-8 | |
| FDA UNII: | T89I34ODAA | |
| MDL: | MFCD00012641 | |
| Molecular Weight: | 248.71181000 | |
| Formula: | C13 H13 Cl N2 O | |
| BioActivity Summary: | listing | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: pharmaceuticals / chemical synthisis
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
Physical Properties:
| Assay: | 95.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Melting Point: | 264.00 to 266.00 °C. @ 760.00 mm Hg |
| Boiling Point: | 421.40 °C. @ 760.00 mm Hg (est) |
| Vapor Pressure: | 0.000001 mmHg @ 25.00 °C. (est) |
| Flash Point: | 284.00 °F. TCC ( 139.80 °C. ) (est) |
| logP (o/w): | 3.173 (est) |
| Soluble in: | |
| water, 13.66 mg/L @ 25 °C (est) | |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| None found |
Suppliers:
| BOC Sciences |
| For experimental / research use only. |
| Harmine Hydrochloride >98%
Odor: characteristic Use: Harmine hydrochloride has potent anti-cancer effects in glioblastoma cells, which is at least partially via inhibition of Akt phosphorylation |
| Coompo |
| For experimental / research use only. |
| Harmine Hydrochloride from Plants ≥98% |
| Penta International |
| HARMINE HYDROCHLORIDE |
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| Harmine hydrochloride ≥98% |
| Sigma-Aldrich: Sigma |
| For experimental / research use only. |
| Harmine Hydrochloride ∼98% |
| TCI AMERICA |
| For experimental / research use only. |
| Harmine Hydrochloride >98.0%(HPLC)(T) |
Safety Information:
| Preferred SDS: View | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
|
intravenous-mouse LD50 38 mg/kg Journal of Pharmacology and Experimental Therapeutics. Vol. 79, Pg. 127, 1943. | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | pharmaceuticals / chemical synthisis | ||
| Recommendation for harmine hydrochloride hydrate usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for harmine hydrochloride hydrate flavor usage levels up to: | |||
| not for flavor use. | |||
Safety References:
| EPI System: | View |
| Chemical Carcinogenesis Research Information System: | Search |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA GENetic TOXicology: | Search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 5359389 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 3 |
| 7-methoxy-1-methyl-9H-pyrido[3,4-b]indole;hydrochloride | |
| Chemidplus: | 0000343271 |
| RTECS: | MG9450000 for cas# 343-27-1 |
References:
| 7-methoxy-1-methyl-9H-pyrido[3,4-b]indole;hydrochloride | |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 5359389 |
| Pubchem (sid): | 134974819 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| CHEMBL: | View |
| HMDB (The Human Metabolome Database): | Search |
| Export Tariff Code: | 2939.99.0000 |
| VCF-Online: | VCF Volatile Compounds in Food |
| ChemSpider: | View |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| None Found |
Occurrence (nature, food, other): note
| rue wild rue seeds Search Trop Picture |
Synonyms:
| harmine hydrochloride | |
| harmine monohydrochloride | |
| harmine, hydrochloride | |
| 7- | methoxy-1-methyl-9H-pyrido(3,4-b)indole hydrochloride |
| 7- | methoxy-1-methyl-9H-pyrido[3,4-b]indole hydrochloride |
| 7- | methoxy-1-methyl-9H-pyrido[3,4-b]indole;hydrochloride |
| 7- | methoxy-1-methylbeta-carboline, chloride |
| 9H- | pyrido(3,4-b)indole, 7-methoxy-1-methyl-, monohydrochloride |
| 9H- | pyrido[3,4-b]indole, 7-methoxy-1-methyl-, hydrochloride (1:1) |
| 9H- | pyrido[3,4-b]indole, 7-methoxy-1-methyl-, monohydrochloride |